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Chemical Research in Chinese Universities 2019年第2期35卷 209-215页

作者： GUO Donggang NI liang WANG liang SHAO Li School of the Environment and Safety Engineering School of Chemistry and Chemical EngineeringJiangsu UniversityZhenjiang 212013R R. China Key Laboratory of Preparation and Application of Environmental Friendly Materials Jilin Normal UniversityMinistry of EducationChangchun 130103P. RChina

A green and sensitive sample separation and purification method coupled with high-perfomiance liquid chromatography(HPLC)was developed for the analysis of chioramphenicol(CAP).One element small molecule alcohol-salt aqueous two-phase system(ATPS)can't effectively adjust the polarity of the system,but binary small molecule alcohol-salt ATPS can adjust the polarity and improve the extraction efficiency of antibiotics.A binary aqueous two-phase system based on 1-propanol+2-propanol and NaH2PO4 system was formed and applied to the separation and purification of trace CAP in real *** influence factors on partition behaviors of CAP were discussed,including the types and mass of salts,the volume ratio of alcohol,the pH,temperature and the standing *** optimal condition was found at pH=5.0,2.5 g of NaH2PO4,3.0 mL of 1-propanol and 2-propanol(volume ratio 1:1)and 30℃by using response surface *** this optimal condition,the extraction efficiency of CAP reached 98.91%,and partition coefficient of CAP was 17.31.

关键词： Binary small molecule alcohol aqueous two-phase system Partition behavior Chloramphenicol Extraction efficiency

Endogenous/exogenous dual stimulation“ROS engineering”amplification combined with autophagy-augmented for efficient ferroptosis therapy

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Nano Research 2025年第1期18卷 597-606页

作者： Pengye Du Pengpeng Lei Yuan liang Ran An Yi Wei Shuyu Liu Jianhao Zheng Hongjie Zhang State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Department of Chemistry Tsinghua UniversityBeijing 100084China

“Reactive oxygen species(ROS)engineering”is one of the most promising anti-tumor treatments developed in recent *** explosion of ROS will cause oxidative stress,thereby inducing tumor cell ***,ROS accumulation in tumor cells is eliminated by endogenous cellular self-regulation *** this work,a kind of endogenous/exogenous dual stimulation nanoagent noted as UMZC is *** reaction occurs between NH_(2)-MIL-88B(Fe)contained in UMZC and the overexpression of endogenous H_(2)O_(2)to generate ROS,amplified by endogenous H_(2)S of colon tumor *** addition,NH_(2)-MIL-88B(Fe)also functions to deplete glutathione(GSH)for stopping it from consuming *** nanoparticles at the core of UMZC convert near-infrared into visible light,which excites zinc phthalocyanine to initiate the photochemical reaction that generates more ROS,thus alleviating the lack of tissue penetration depth for visible *** agonist chitosan oligosaccharides induce enhancement of cellular autophagy for disrupting cellular metabolic stress and the resistance to oxidative stress of tumor cells,allowing“ROS engineering”to fully exert anti-tumor *** of ROS generation,GSH depletion,and induced cellular autophagy caused by nanoagents have promoting effects on the occurrence of ***,the nanoagents show the ability to effectively treat colon tumors.

关键词： reactive oxygen species(ROS)engineering upconversion nanoparticles cellular autophagy ferroptosis tumor therapy

An Anisotropic Biomimetic Lemongrass Flexible Piezoelectric Actuator-Inhibitory Regression

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Journal of Bionic Engineering 2024年第4期21卷 1817-1829页

作者： Tianwei liang Yunhong liang Jiru Wang Hu Huang Zhi Xu Hongwei Zhao Key Laboratory of CNC Equipment Reliability Ministry of EducationJilin UniversityChangchun130022China School of Mechanical and Aerospace Engineering Jilin UniversityChangchun130022China Institute of Structured and Architected Materials Liaoning Academy of MaterialsShenyang110167China The Key Laboratory of Bionic Engineering Ministry of EducationJilin UniversityChangchun130025China

At present,the existing piezoelectric stick-slip actuators have an inherent back-slip problem,which greatly limits the development and application of stick-slip *** order to inhibit the regression phenomenon,a new bionic lemongrass stickslip actuator was prepared by using polymer PDMS to replicate natural biological *** surface microstructure of the grass was copied by PDMS,and the PDMS film was *** rigid and flexible bionic friction pair was further prepared,and the flexible anisotropic PDMS stick slip actuator was *** was found that the anisotropic friction characteristics of the surface microstructure of the grass inhibited the anti-sliding motion,and the elastic potential energy of the PDMS film improved the output characteristics of the *** adjusting the input voltage to control the contact between the drive foot and the rotor,the rigid and flexible hybrid drive can be realized and the backsliding phenomenon can be *** actuator is compact,lightweight and can achieve high speed and high resolution output without preloading force,which has important application value in the field of fast and accurate positioning with load limitation.

关键词： Piezoelectric actuator Bionic surface Friction Surface friction Flexible film

Enhanced photocatalytic activities of Nd-doped TiO2 under visible light using a facile sol-gel method

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Journal of Rare Earths 2020年第2期38卷 148-156页

作者： Jicai liang Jingya Wang Kexian Song Xiaofeng Wang Kaifeng Yu Ce liang Key Laboratory of Automobile Materials Ministry of Educationand College of Materials Science and EngineeringJilin UniversityChangchun 130025China Roll Forging Research Institute Jilin UniversityChangchun 130025China State Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of ChemistryJilin UniversityChangchun 130025China

Titanium dioxide nanoparticles modified with neodymium in the range of 1 mol% to 5 mol% were prepared with template-free sol-gel *** structures of obtained samples were characterized by X-ray powder diffraction analysis.X-ray photoelectron spectroscopy,scanning electron microscopy,transmission electron microscopy and diffuse reflectance *** photocatalytic activity of the obtained samples was evaluated by photodegradation of methyl orange in aqueous solution under ultraviolet-visible(λ> 350 nm) and visible(λ> 420 nm) *** experimental results show that the 1 mol% Nd-doped TiO2 exhibits the highest photocatalytic activity,of which the degradation can reach to 96.5% under visible *** to the XRD results,the pristine samples are combined with anatase TiO2 and rutile *** the Nd-doped TiO2 samples are anatase TiO2 *** transformation has made an obvious promotion of photocatalyst activity after modification.

关键词： Nd-doped titanium dioxide Sol-gel method Visible light photocatalyst Mechanism of up-conversion Rare earths

Optimal Design and Mechanical Simulation of Rubber bushing with Convex Hull Structure Based on Bionics

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Journal of Bionic Engineering 2023年第5期20卷 2018-2029页

作者： Ce liang Min Li Jicai liang Shaoqiang Wang Qigang Han Yi Li Key Laboratory of Automobile Materials Ministry of Educationand College of Materials Science and EngineeringJilin UniversityChangchun130025China Roll Forging Research Institute Jilin UniversityChangchun130025China School of Computer Science and Technology Changchun UniversityChangchun130022China

Inspired by the safe landing of cats falling from high altitudes,a bionic flexible rubber bushing structure is proposed and its motion characteristics are systematically studied to explore its potential application in the suppression of *** convex hull structure on the bushing surface is abstracted from the cat’s claw pad,and the hyper-viscoelastic model is selected as the constitutive model of the rubber *** addition,the design with the best vibration damping effect is finally obtained by reasonably adjusting the amount of radial compression and distribution of bionic ***,under the same conditions,the test results of the dynamic characteristics of the bushing verify the accuracy of the simulation *** results show that the convex hull bionic structure designed in this paper can effectively change the motion characteristics of the rubber bushing under various working conditions,which provides new inspiration or potential possibility for the design of rubber bushing in the future.

关键词： Rubber bushing Bionic design Finite element analysis Vibration isolator Radial compression

Effects of heat shock protein-antigen peptide complexes (HACs) in melanoma B16 cell line on transplanted tumor development in mice

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白求恩医科大学学报 2001年第5期27卷 457-460页

作者： GONG Shou liang,YANG Ying,LI Xiu juan,FU Shi bo,SUN Zu yue,CHEN Sha li,LI Xiu yi (MH Radiobiology Research Unit,jilin University,Changchun 130021 China)

目的 :建立黑色素瘤 B16细胞热休克蛋白 -抗原肽复合物 (HACs)的制备方法并测其抑瘤效应。方法 :应用 Sephacryl S- 2 0 0凝胶过滤制备 HAC粗提物 ,应用 SDS- PAGE纯化 HACs,并测其抑瘤效应。结果 :应用 SDS- PAGE纯化的 HAC6 0、 HAC75... 详细信息

目的 :建立黑色素瘤 B16细胞热休克蛋白 -抗原肽复合物 (HACs)的制备方法并测其抑瘤效应。方法 :应用 Sephacryl S- 2 0 0凝胶过滤制备 HAC粗提物 ,应用 SDS- PAGE纯化 HACs,并测其抑瘤效应。结果 :应用 SDS- PAGE纯化的 HAC6 0、 HAC75和 HAC97不同程度地降低肿瘤发生率 ,延迟肿瘤发生时间和减慢肿瘤生长速度。结论 :6 0 0 0 0～ 970 0 0

关键词：黑色素瘤 B16细胞热休克蛋白-抗原肽复合物 HACs 抑瘤效应

AN APPLICATION OF THE NEURAL NETWORK IN THE NEAR-FIELD ACOUSTIC HOLOGRAPHY

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AN APPLICATION OF THE NEURAL NETWORK IN THE NEAR-FIELD ACOUS...

2006年中国机械工程学会年会暨中国工程院机械与运载工程学部首届年会

作者： GAO Yinhan, SONG Dan, liang Jie, ZHOU Xiaohua Center of Test Science of jilin University, jilin University Changchun 130022 China

The near-field acoustic holography (NAH) is an effective and useful noise measurement method. There are many methods for reconstruction of the sound source, but the measurement circumstance is limited

关键词： Neural network near-field acoustic holography noise source random noise.

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极端酶的研究进展

生物化学与生物物理进展 2002年第6期29卷 847-850页

作者：翁樑冯雁吉林大学分子酶学工程实验室长春130023

极端酶具有超常的生物学稳定性 ,能够在极端温度、pH、压力和离子强度下表现出生物学活性 ,因此极端酶为生物催化和生物转化提供了良机 .新的极端物种的发现、基因组序列的确定及基因工程技术的应用 ,加快了发现和制备新酶的进程 .蛋白... 详细信息

极端酶具有超常的生物学稳定性 ,能够在极端温度、pH、压力和离子强度下表现出生物学活性 ,因此极端酶为生物催化和生物转化提供了良机 .新的极端物种的发现、基因组序列的确定及基因工程技术的应用 ,加快了发现和制备新酶的进程 .蛋白质工程和定向进化技术进一步改善酶的活性和特异性 ,促进了极端酶的工业应用 .对极端酶的研究加深了人们对酶稳定性机制的理解。

关键词：极端酶研究进展异源表达生物催化

Recent progress on dense nuclear matter in skyrmion approaches

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Science China(Physics,Mechanics & Astronomy) 2017年第3期60卷 1-24页

作者： Yong liang Ma Mannque Rho Center of Theoretical Physics and College of Physics Jilin University Institut de Physique Th'eorique CEA Saclay

The Skyrme model provides a novel unified approach to nuclear physics. In this approach, single baryon, baryonic matter and medium-modified hadron properties are treated on the same footing. Intrinsic density dependence(IDD) reflecting the change of vacuum by compressed baryonic matter figures naturally in the approach. In this article, we review the recent progress on accessing dense nuclear matter by putting baryons treated as solitons, namely, skyrmions, on crystal lattice with accents on the implications in compact stars.

关键词： Skyrme model hidden symmetries skyrmion crystal holographic nucleon BPS nuclei compact stars

AN IMPROVEMENT OF THE RECURSIVE CLOSED-FORM ALGORITHM FOR NON-MINIMUM PHASE FIR SYSTEM IDENTIFICATION

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Journal of Electronics(China) 1993年第2期10卷 188-192页

作者：梁应敞王树勋戴逸松 jilin University of Technology Changchun 130022

An improved algorithm which is based on the recursive closed-form algorithm fornon-minimum phase FIR system identification via higher order statistics is *** order toincrease the parametric estimation accuracy,the improved algorithm uses the optimal iterativemethod to seek the nonlinear least-square ***,the simulation examples are alsogiven.

关键词： Non-minimum phase FIR system Higher order statistics Parameter estimation Iterative method