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类风湿性关节炎的影像学表现

实用医学影像杂志 2009年第2期10卷 106-108页

作者：兰剑明崔飞云黄必润张秀兰郑国勤陈解放湖北省荆州市肿瘤医院放射科湖北荆州434002

目的探讨类风湿性关节炎的影像特征,提高其诊断准确率。方法对经临床及实验室确诊的56例类风湿性关节炎患者的影像学表现进行回顾性分析。结果在56例的X线片上,手足小关节附近软组织呈梭形肿胀见于7例。表现为骨质疏松、关节间隙狭窄、... 详细信息

目的探讨类风湿性关节炎的影像特征,提高其诊断准确率。方法对经临床及实验室确诊的56例类风湿性关节炎患者的影像学表现进行回顾性分析。结果在56例的X线片上,手足小关节附近软组织呈梭形肿胀见于7例。表现为骨质疏松、关节间隙狭窄、骨性关节面骨皮质边缘不规整43例。骨质疏松、破坏、缺损、关节半脱位、骨性强直6例。结论类风湿性关节炎的影像学表现具有一定特征,临床、影像、实验室相结合可提高本病的诊断准确率。

关键词：类风湿性关节炎放射学检查体层摄影术,X线计算机磁共振成像

Oscillation-specific nodal alterations in early to middle stages Parkinson’s disease

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Translational Neurodegeneration 2019年第1期8卷 450-465页

作者： Xiaojun Guan Tao Guo Qiaoling Zeng Jiaqiu Wang Cheng Zhou Chunlei Liu Hongjiang Wei Yuyao Zhang Min Xuan Quanquan Gu Xiaojun Xu Peiyu huang Jiali Pu Baorong Zhang Min-Ming Zhang Department of Radiology The Second Affiliated HospitalZhejiang University School of MedicineNo.88 Jiefang RoadShangcheng DistrictHangzhou 310009China Department of Neurology The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Helen Wills Neuroscience Institute University of CaliforniaBerkeleyCAUSA Department of Electrical Engineering and Computer Sciences University of CaliforniaBerkeleyCAUSA

Background:Different oscillations of brain networks could carry different dimensions of brain *** aimed to investigate oscillation-specific nodal alterations in patients with Parkinson’s disease(PD)across early stage to middle stage by using graph theory-based ***:Eighty-eight PD patients including 39 PD patients in the early stage(EPD)and 49 patients in the middle stage(MPD)and 36 controls were recruited in the present *** theory-based network analyses from three oscillation frequencies(slow-5:0.01–0.027 Hz;slow-4:0.027–0.073 Hz;slow-3:0.073–0.198 Hz)were *** metrics(*** degree centrality,betweenness centrality and nodal efficiency)were ***:Our results showed that(1)a divergent effect of oscillation frequencies on nodal metrics,especially on nodal degree centrality and nodal efficiency,that the anteroventral neocortex and subcortex had high nodal metrics within low oscillation frequencies while the posterolateral neocortex had high values within the relative high oscillation frequency was observed,which visually showed that network was perturbed in PD;(2)PD patients in early stage relatively preserved nodal properties while MPD patients showed widespread abnormalities,which was consistently detected within all three oscillation frequencies;(3)the involvement of basal ganglia could be specifically observed within slow-5 oscillation frequency in MPD patients;(4)logistic regression and receiver operating characteristic curve analyses demonstrated that some of those oscillation-specific nodal alterations had the ability to well discriminate PD patients from controls or MPD from EPD patients at the individual level;(5)occipital disruption within high frequency(slow-3)made a significant influence on motor impairment which was dominated by akinesia and ***:Coupling various oscillations could provide potentially useful information for large-scale network and progressive oscillation-specific no

关键词： Parkinson’s disease Network Functional magnetic resonance imaging Oscillation frequency Graph theory analysis Akinesia and rigidity

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男性尿频诊断调查

中国现代医生 2009年第9期47卷 47-48页

作者：黄振国李解方丁平曹友汉刘志文段有军丁韬南华大学附属第一医院泌尿外科湖南衡阳421001

目的了解门诊医师对男性尿频患者的诊断情况。方法对332例以尿频为突出症状的男性患者就诊的病史、体查、检查及诊断结果进行调查,分析诊断中各组数据情况。结果小儿组中无检查比最高,成人组中无体查比最高,不能确定诊断数多,且两组中... 详细信息

目的了解门诊医师对男性尿频患者的诊断情况。方法对332例以尿频为突出症状的男性患者就诊的病史、体查、检查及诊断结果进行调查,分析诊断中各组数据情况。结果小儿组中无检查比最高,成人组中无体查比最高,不能确定诊断数多,且两组中误诊率高,老年组中漏诊率高。结论男性尿频患者诊断中不重视病史、体查和检查,误诊漏诊率较高。

关键词：男性尿频诊断调查

Impact Analysis of the Aging Silicone Oil in the Damper on the Torsional Vibration of the Crankshaft of the Heavy-duty Vehicle Diesel Engine

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Impact Analysis of the Aging Silicone Oil in the Damper on t...

Induction of cell cycle arrest and apoptosis by tubeimoside I isolated from Bolbostemma paniculatum in HeLa cells

2019中国汽车工程学会年会

作者： Zhai Liming Wang Enzhen Xu Weiguo huang Chenghai Yang Zhenguo Engine Business Division of FAW jiefang Automotive Co. Ltd. School of Vehicle and Mobility of Tsinghua University

The silicone-oil damper of the diesel engine has significant effects on reducing the torsional vibration and the torsional stress of the *** nature to maintain viscosity of the silicone oilis an important indicator when we evaluate the reliability of a silicone-oil *** a heavy-dutyvehicle diesel engine which meets China 6 emission standards as an object of research,this paper used AVL EXCITE to establish thetorsional numerical model of the crankshaft which considers coupling effect of the non-linear stiffness and the damping of the silicon-oil damper,and discussed the impacts of the silicon oil in different viscosities on the amplitude of the torsional vibration and the dynamical tangential *** numerical results were also compared with the measurements in the dynamical durability test in which applying the time *** results indicate the measurements in which the diesel engine run 953 hours turn out to be close to the simulation and demonstrate the accuracy of thedynamical numerical *** the viscosity of the silicone oil reduces not more than 40%,its impacts on the torsional vibration and the torsional stress of the crankshaft are ***,with the viscosity increasing to 70%,the 6 th-order vibration amplitude approach to the requirement limit,so that should be taken into *** speaking,the changes of the silicone oil viscosity will not have great impacts on the damper under normal *** optimal performance,there should be the enhanced durability to the silicone oil in the damper and should take some effective measures to avoid the overquickdecrease of the silicone oilviscosity.

关键词： diesel engine torsional vibration silicone-oil damper silicone-oil deterioration simulation

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Induction of cell cycle arrest and apoptosis by tubeimoside ...

第九次全国生物物理大会学术会议

作者： Ma Run-di, Su Wei-ming, Shao Hai-yan, Liao Ming-neng, huang Lai-zhen, He Dong-mei, Yu Li-jian Guangdong Provincial Key Laboratory of Marine Materia Medica, Zhanjiang Ocean University, Zhanjiang 524025, China 1. Project supported by the Natural Science Foundation of Guangdong Province 2. Correspondence to Prof Yu Li-jian: Guangdong Provincial Key Laboratory of Marine Materia Medica, Zhanjiang Ocean University, Zhanjiang jiefang East Avenue 40, 524025, China Phn 86-759-238-2424. Fax 86-759-238-2041. E-mail vwvi@***

＜正＞ In order to study the mechanisms by which tubeimoside I exert its antitumor effect, its effects on cell division cycle and cell death were investigated in HeLa cells. Growth inhibition was measured by MTT assay after 24, 48 and 72h of treatment with tubeimoside Ⅰ. Tubeimoside I displayed strong growth inhibitory effect against HeLa cells with estimated IC50 values of 20.0, 18. 8, 8. 9 μM. Exposure of HeLa cells to tubeimoside I led to the induction of cell cycle arrest at G2/M phase and massive and rapid apoptosis as determined by flow cytometry, fluorescence and electron microscopy, and gel electrophoresis of fragmented DNA.

关键词： Tubeimoside I Cell cycle arrest Apoptosis HeLa cells

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多轴车辆线控液压转向系统设计及转角控制

中国机械工程 2022年第14期33卷 1741-1750页

作者：刘俊石朝欢林贝清黄鹤合肥工业大学汽车与交通工程学院合肥市230009 一汽解放柳州特种汽车有限公司柳州市545000

为减小多轴转向车辆货厢部位的第三轴转向轮转向磨损,要求该车轮与驾驶室部位的前转向轮转角关系满足阿克曼转向原理。针对某型号8×2四轴重型车辆,设计出一种第三轴线控液压转向系统,并建立其动力学模型,设计了基于指数趋近律的滑模控... 详细信息

为减小多轴转向车辆货厢部位的第三轴转向轮转向磨损,要求该车轮与驾驶室部位的前转向轮转角关系满足阿克曼转向原理。针对某型号8×2四轴重型车辆,设计出一种第三轴线控液压转向系统,并建立其动力学模型,设计了基于指数趋近律的滑模控制器对第三轴转向轮转角进行控制,选取典型工况对所设计的控制器进行了仿真分析,并进行实车试验验证。研究结果表明:基于指数趋近律的滑模控制比基于比例切换函数的滑模控制及开环控制响应更快速、趋近目标值时间及超调持续时间更短、稳态差值更小;与采用机械液压转向系统相比,安装基于该控制器的线控液压转向系统不仅能显著提高第三轴轮胎的转向抗磨损性能,同时也改善了整车的转向性能。

关键词：多轴车辆线控液压转向系统滑模控制转向磨损

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ACOUSTIC EMISSION SIGNAL RESPONSE OF PIEZOELECTRIC FIBER COMPOSITES

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ACOUSTIC EMISSION SIGNAL RESPONSE OF PIEZOELECTRIC FIBER COM...

2015全国压电和声波理论及器件技术研讨会

作者： Fan LU Xiu-juan Lin Bo GENG Yang LI Shi-feng huang Shandong Provincial Key Lab.of Preparation and Measurement of Building Materials University of Jinan Department of Qualify Assurance Faw Jiefang Qingdao Automobile Co.Ltd.

Piezoelectric fiber composites（PFCs）were fabricated by cutting-filling methods to be used as acoustic emission（AE）*** AE sources were simulated by pencil lead broken,the AE signals were collected in the test plate and the linear localization of sound source was measured based on acoustic emission *** results showed that the obtained AE signal amplitudes and voltages of PFCs exhibited dependence on the measuring distances and *** AE signal amplitudes were different in the orthogonal direction which indicated that the PFCs exhibited well orthotropic *** attenuation curves showed that the trend of signal attenuation gradually slowed down as the distance *** lead broken signals were acquired by the sensors for each time and the accuracy of linear positioning was above a percentage of 95,which indicated that the PFCs possessed good sensitivity and good signal responses to achieve the purpose of positioning and had high accuracy in the process of linear localization.

关键词： Piezoelectric fiber Acoustic emission Orthotropic property Signal response Linear localization

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重力数据探测地下目标的贝叶斯方法研究

大地测量与地球动力学 2024年第2期44卷 154-159,176页

作者：黄佳喜边少锋纪兵海军工程大学电气工程学院武汉430033 中国地质大学(武汉)地质探测与评估教育部重点实验室武汉430074

针对地下目标空间位置和形状均未知的情况,基于重力数据,分别以区域测量和线测量2种场景进行建模分析,研究贝叶斯推断用于地下目标探测的效果。结果表明,将贝叶斯推断用于重力梯度探测,比微重力探测更具优势,能有效反演出目标的未知参数。

关键词：地下目标探测重力异常重力梯度贝叶斯推断最高密度区间

45钢上堆焊Fe-C-Cr-Nb合金的压缩疲劳行为

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焊接学报 2019年第10期40卷 54-59,I0003页

作者：任振安郑思强黄飞刘武慕吉林大学长春130022 一汽解放汽车有限公司长春130011 东北电力大学吉林132012

针对水泥挤压辊的压缩疲劳工况,采用自行设计的双切口疲劳试样,试验了45钢母材上堆焊六种Fe-CCr-Nb合金的压缩疲劳行为.对疲劳试样表面进行原位观察和激光共聚焦裂纹分析,切口的应力应变集中促进其下方热影响区(HAZ)局部滑移线聚集并形... 详细信息

针对水泥挤压辊的压缩疲劳工况,采用自行设计的双切口疲劳试样,试验了45钢母材上堆焊六种Fe-CCr-Nb合金的压缩疲劳行为.对疲劳试样表面进行原位观察和激光共聚焦裂纹分析,切口的应力应变集中促进其下方热影响区(HAZ)局部滑移线聚集并形成塑性变形区,同时在切口底部边缘萌生疲劳裂纹,穿过堆焊合金扩展进入HAZ.疲劳裂纹还在熔合线萌生并扩展,最后导致疲劳失效.试验结果表明,疲劳试样的a-N曲线近似为直线.堆焊合金基体组织主要为高硬度马氏体时,疲劳裂纹扩展速率大,疲劳寿命仅5万次;基体组织为较软的铁素体或奥氏体时,裂纹扩展速率小,疲劳寿命长达54万次.

关键词：压缩疲劳堆焊合金微观组织疲劳寿命挤压辊