检索结果-南通市图书馆

Genetically modified pigs with CD163 point mutation are resistant to HP-PRRSV infection

Zoological Research 2024年第4期45卷 833-844页

作者： Ying Liu Lin Yang Hong-Yong Xiang Ming Niu Jia-Cheng Deng Xue-Yuan Li wen-jie hao Hong-Sheng Ou-Yang Tong-Yu Liu Xiao-Chun Tang Da-Xin Pang Hong-Ming Yuan State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Animal Genome Editing Technology Innovation CenterCollege of Animal SciencesJilin UniversityChangchunJilin 130062China Chifeng Best Genetics Technology Co. Ltd.ChifengNei Mongol 024000China Chongqing Jitang Biotechnology Research Institute Co. Ltd.Chongqing 400015China

Porcine reproductive and respiratory syndrome(PRRS)is a globally prevalent contagious disease caused by the positive-strand RNA PRRS virus(PRRSV),resulting in substantial economic losses in the swine *** the CD163 SRCR5 domain,either through deletion or substitution,can eff1ectively confer resistance to PRRSV infection in ***,large fragment modifications in pigs inevitably raise concerns about potential adverse effects on growth *** the impact of genetic modifications on normal physiological functions is a promising direction for developing PRRSV-resistant *** the current study,we identified a specific functional amino acid in CD163 that influences PRRSV *** infection experiments conducted on Marc145 and PK-15CD163 cells illustrated that the mE535G or corresponding pE529G mutations markedly inhibited highly pathogenic PRRSV(HP-PRRSV)proliferation by preventing viral binding and ***,individual viral challenge tests revealed that pigs with the E529G mutation had viral loads two orders of magnitude lower than wild-type(WT)pigs,confirming effective resistance to *** of the physiological indicators and scavenger function of CD163 verified no significant differences between the WT and E529G *** findings suggest that E529G pigs can be used for breeding PRRSV-resistant pigs,providing novel insights into controlling future PRRSV outbreaks.

关键词： PRRSV CD163 Point mutation E529G Pigs

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

新媒体语境下大学生体育行为的现状、特征及其提升路径

引用

重庆工商大学学报（社会科学版） 2024年第4期41卷 180-188页

作者：胡磊揭浩文重庆工商大学体育学院重庆400067

新媒体迅速发展增加了体育信息传播的途径和范围。为探究新媒体语境下信息时代的体育传播对大学生体育行为的影响,本文对重庆市4所高校的大学生参与体育活动形式、获取传媒信息的渠道以及体育行为需求等情况进行调查,通过文献资料整理... 详细信息

新媒体迅速发展增加了体育信息传播的途径和范围。为探究新媒体语境下信息时代的体育传播对大学生体育行为的影响,本文对重庆市4所高校的大学生参与体育活动形式、获取传媒信息的渠道以及体育行为需求等情况进行调查,通过文献资料整理、问卷调查、数理统计等研究方法,对新媒体语境下信息传播对重庆市大学生体育理念和行为、特征等问题进行研究,为大学生形成科学合理的锻炼方式、养成良好的体育行为等提供参考,为新媒体信息在新时代高校体育工作的应用提供理论依据。

关键词：新媒体语境大学生体育行为体育意识

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Relapsing polychondritis causing breathlessness: Two case reports

引用

World Journal of Clinical Cases 2022年第23期10卷 8360-8366页

作者： Song-Yu Zhai Yu-hao Zhang Ru-Yan Guo jie-wen hao Shu-Xin wen Department of Otorhinolaryngology Head and Neck Surgery Xi’an Fourth HospitalXi’an 710004Shaanxi ProvinceChina Department of Otorhinolaryngology Head and Neck Surgery Shanxi Bethune HospitalTaiyuan 030000Shanxi ProvinceChina Department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of NanyangNanyang 473000Henan ProvinceChina Department of Otorhinolaryngology Head and Neck Surgery The Third Clinical College of Shanxi Medical UniversityTaiyuan 030000Shanxi ProvinceChina

BACKGROUND Relapsing polychondritis is a rare multisystem autoimmune disease that mainly involves systemic cartilage and proteoglycan-rich *** the larynx and trachea are involved,the patient’s condition deteriorates *** relapsing polychondritis becomes more advanced,the airways collapse and treatment is difficult,rendering a poor ***,the diagnosis method,treatment strategy and prognosis of relapsing polychondritis with larynx and trachea involvement need to be elucidated to improve clinicians’awareness of the *** SUMMARY A man and a woman were admitted because of *** polychondritis was diagnosed after a series of accessory *** were both treated with glucocorticoids and immunosuppressants,and underwent tracheotomy as their breathing difficulties could not be relieved by the *** The two cases highlight the importance of the timely diagnosis,full evaluation and initiating individualized treatment of relapsing polychondritis with larynx and trachea ***,bronchoscopy and pathological examination are helpful in diagnosis of this disease.

关键词： Relapsing polychondritis Larynx Trachea Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Determinants of saturation magnetic flux density in Fe-based metallic glasses: insights from machine-learning models

引用

Rare Metals 2024年第10期43卷 5256-5267页

作者： jie Xiong Bo-wen Bai hao-Ran Jiang Angeles Faus-Golfe Materials Genome Institute Shanghai University Institute of Special Environments Physical Sciences Harbin Institute of Technology Laboratoire de Physique des 2 Infinis Irene Joliot-Curie (IJCLab) CNRS-IN2P3Universite′Paris-Saclay

Fe-based metallic glasses have garnered significant attention due to their low coercivity force and core loss. Enhancing the saturation magnetic flux density(Bs) of Fe-based metallic glasses is crucial for their industry applications. This work constructed a dataset comprising330 training data and 157 test data. The support vector regression model surpassed the tree-based ensemble models in the test set and demonstrated comparable accuracy to the tree-based ensemble models in the training set. Additionally, we proposed an indicator for Bsbased on symbolic regression. This newly proposed indicator exhibits a Pearson correlation coefficient exceeding 0.92 with Bs. The present work provides a simple and accurate formula for predicting the Bsof Fe-based amorphous alloys, demonstrating the effectiveness of machine learning approaches in discovering novel soft magnetic materials.

关键词： Fe-based metallic glasses Machine learning Saturation magnetic flux density Symbolic regression

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

The Crystallization Behavior of L-Poly(lactic acid)/Polypropylene Blends:The Acceleration for Both L-Poly(lactic acid)and Polypropylene

引用

Chinese Journal of Polymer Science 2024年第6期42卷 775-786页

作者： Shuang-Cheng Li Wei-Jia Zhou wen-jie Wu Jun Shao Shui-Liang Chen hao-Qing Hou Sheng Xiang College of Chemistry&Chemical Engineering and Nanofiber Engineering Center of Jiangxi Province Jiangxi Normal UniversityNanchang330022China National Engineering Research Center for Carbohydrate Synthesis/Key Lab of Fluorine and Silicon for Energy Materials and Chemistry of Ministry of Education Jiangxi Normal UniversityNanchang330022China wenzhou Institute University of Chinese Academy of SciencesWenzhou325001China

For a polymer/polymer dismissible blend with two crystallizable components,the crystallization behavior of different components and the reciprocal influences between different crystals are interesting and important,but did not investigate in *** this study,the L-poly(lactic acid)/polypropylene(PLLA/PP)blends with different weight ratios were prepared by melt mixing and the crystallization behavior of the blends were *** showed that the crystalline structures of PLLA and PP were not altered by the *** the crystallization of PLLA,both the diffusion of chain segments and crystallization rate were enhanced under the existence of PP *** the crystallization of PP,its crystallization rate was depressed under the existence of amorphous PLLA molecular *** the PP crystallized from the existence of PLLA crystals,although the diffusion rate of PP was reduced by PLLA crystals,the nucleation positions were obviously enhanced,which accelerated the formation of PP *** investigation would supply more basic data for the application of PLLA/PP blend.

关键词： L-poly(lactic acid) Polypropylene Blends Crystalization behavior Crystallization acceleration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Isotopic insights on quantitative assessments of interaction of eco-hydrological processes in multi-scale karst watersheds

引用

International Soil and Water Conservation Research 2024年第1期12卷 156-170页

作者： Zhuo hao Yang Gao Qingwen Zhang wen wen Agricultural Clean Watershed Research Group Institute of Environment and Sustainable Development in AgricultureCAASBeijing100081China Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources ResearchCASBeijing100101China School of Humanities and Social Sciences Beijing Institute of TechnologyBeijing100081China

The dynamics of hydrological processes and the storage mechanisms of karst water resources are the most important issues in karst *** impact of environmental changes on water quantity,and the evaluation and quantification of eco-hydrological processes remain poorly *** this study,high-frequency continuous monitoring in multi-scale karst watersheds in Southwest China combined the approaches of water isotopes and the hybrid single-particle lagrangian integrated trajectory(HYSPLIT)model to identify the recharge mechanisms between atmospheric vapor,rainfall,surface water,and groundwater,and to reveal the interaction of eco-hydrological *** dominant moisture sources in Puding(PD)County were the Indian Ocean(43-69%)and local moisture(24-33%).Theδ^(18)O and deuterium excess(d-excess)values showed a positive correlation indicating that secondary or sub-cloud evaporation was prominent in the wet *** water line-conditioned excess(lc-excess)indicated that karst water interacted with recent precipitation,groundwater,and evaporation across *** to its specific hydrogeological structure,surface water and rainwater have a higher contribution rate to groundwater *** Chenqi stream replenished the Houzhai River mainly in the form of groundwater,with percentages ranging from 38.1 to 93.5%in the wet season,and 47.8-80.1%in the dry *** the Houzhai outlet,surface water and groundwater interconverted frequently with a percentage of 45.6-49.1%.We believe this is the first systematic study to quantify the supply relationship between water vapor transport,rainfall,surface water and groundwater in the Chinese karst zone,making a significant move forward in the field of karst hydrological processes and improving the efficiency of water resource evaluation and management.

关键词： Stable isotope Moisture sources Water cycle Karst watersheds

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Decomposition of pre-existing Au–P clusters induced in situ a-Fe grains uniformization in Fe–P-based nanocrystalline alloys

引用

Rare Metals 2024年第10期43卷 5242-5255页

作者： Min-hao Han Cheng Sun Guo-Guo Xi Yang Meng Qiang Luo Xue-Qian Yu wen-Feng Zhang hao Liu Hong-jie Xu Tao Zhang Key Laboratory of Aerospace Materials and Performance(Ministry of Education) School of Materials Science and EngineeringBeihang University Laboratory of Functional Fiber Materials Institute of Bast Fiber CropsChinese Academy of Agricultural Science School of Materials Science and Engineering Jiangsu Key Laboratory for Advanced Metallic MaterialsSoutheast University Institute for Advanced Materials North China Electric Power University Center for Advanced Analysis and Computational Science Zhengzhou University

In Fe-based amorphous-/nanocrystalline ribbons,the uniformization and refinement of a-Fe grains are key aspects for optimizing their soft magnetic and mechanical ***,the Fe–P–C–B nanocrystalline alloy system was selected for *** produced as-spun ribbons with pre-existing nanocrystals through melt-quenching and then obtained a well-distributed a-Fe nanocrystalline structure through annealing below the first crystallization onset temperature （633 K）resulting in excellent magnetic properties (saturation magnetization of 1.65 T and coercivity of 1.6 A·m-1)ultra-wide annealing temperature window （from 613 to 733 K）,and extremely high annealing stability （up to 480 min at 633 K）.Furthermore,we propose a new in situ two-step mechanism for the uniformization of a-Fe nanocrystals,which is separately induced by the decomposition of the Au–P clusters and the pre-existing a-Fe nanocrystals during *** work underscores the crucial significance of micro-alloying via metastable clusters primarily influenced by metal-phosphide interactions in the process of refining a-Fe ***,i introduces a new principle for optimizing the comprehensive properties of Fe-based amorphous/nanocrystalline alloys.

关键词： Fe-based nanocrystalline alloys In-situ nano-crystallization Micro-alloying Soft magnetic property

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Weakly Approximate Diagonalization of Homomorphisms into Finite von Neumann Algebras

引用

Acta Mathematica Sinica,English Series 2024年第9期40卷 2187-2194页

作者： wen Hua QIAN Jun hao SHEN wen Ming WU School of Mathematical Sciences Chongqing Normal UniversityChongqing 401331P.R.China Department of Mathematics and Statistics University of New HampshireDurhamNH 03824USA

Let A be a unital C^(∗)-algebra and B a unital C^(∗)-algebra with a faithful traceτ.Let n be a positive *** give the definition of weakly approximate diagonalization(with respect toτ)of a unital homomorphismφ:A→Mn(B).We give an equivalent characterization of McDuff Ⅱ_(1) *** show that,if A is a unital nuclear C^(∗)-algebra and B is a type Ⅱ_(1) factor with faithful traceτ,then every unital^(∗)-homomorphism φ:A→M_(n)(B)is weakly approximately *** B is a unital simple infinite dimensional separable nuclear C^(∗)-algebra,then any finitely many elements in Mn(B)can be simultaneously weakly approximately diagonalized while the elements in the diagonals can be required to be the same.

关键词： Weakly approximately diagonalizable McDuff factors nuclear hyperfinite

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact of initial fluctuations and nuclear deformations in isobar collisions

引用

Nuclear Science and Techniques 2024年第6期35卷 155-162页

作者： Jian-Fei Wang hao-jie Xu Fu-Qiang Wang Department of Modern Physics University of Science and Technology of ChinaHefei 230026China School of Science Huzhou UniversityHuzhou 313000China Strong-Coupling Physics International Research Laboratory(SPiRL) Huzhou UniversityHuzhou 313000China Department of Physics and Astronomy Purdue UniversityWest LafayetteIN 47907USA

Relativistic isobar^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zrcollisions have revealed intricate differences in their nuclear size and shape,inspiring unconventional studies of nuclear structure using relativistic heavy ion *** this study,we investigate the relative differences in the mean multiplicityR_()and the secondR_(ε2)and third-order eccentricityR_(ε3)between isobar collisions using initial state Glauber *** is found that initial fluctuations and nuclear deformations have negligible effects on R_()in most central collisions,while both are important for the R_(ε2)and R_(ε3),the degree of which is sensitive to the underlying nucleonic or sub-nucleonic degree of *** features,compared to real data,may probe the particle production mechanism and the physics underlying nuclear structure.

关键词： Relativistic isobar collisions Initial fluctuations Nuclear deformation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ZnO/ZnS heterostructure in N-doped porous carbon for anchoring-diffusion-conversion of polysulfides for high-performance lithium-sulfur batteries

引用

Rare Metals 2024年第8期43卷 3661-3676页

作者： Fei Wang Rong-Wei Huang wen-Chang Han Chun-Man Yang wen-hao Yang Peng Dong Chao-Ling Wu Yi-Yong Zhang Xue Li Ying-jie Zhang National Local Joint Engineering Research Center for LithiumIon Batteries and Materials Preparation Technology Key Laboratory of Advanced Batteries Materials of Yunnan ProvinceFaculty of Metallurgical and Energy EngineeringKunming University of Science and TechnologyKunming 650093China Engineering Research Center of Alternative Energy Materials and Devices Sichuan UniversityMinistry of EducationChengdu 610065China

The shuttle effect of polysulfides is one of the key factors hindering the commercialization of lithiumsulfur batteries(LSBs).Owing to their high conductivity and advantageous structure,heterostructures can be used in sulfur fixation and catalysis of *** this study,a flower-shaped ZnO/ZnS heterostructure on a nitrogendoped porous carbon(NPC) sulfur host was *** ZnO/ZnS heterostructure regulates the electronic structure of the material and exhibits higher metal-like ***,the ZnO/ZnS heterostructure combines the strong adsorption property of ZnO and the high catalytic ability of ZnS to realize the anchoring-diffusionconversion of lithium poly sulfides(LiPSs).Results reveal that the developed ZnO/ZnS@NPC/S cathode has excellent electrochemical performance in LSBs,achieving a high discharge specific capacity of 1365.3 mAh·g^(-1) at 0.1C and excellent rate capability(719 mAh·g^(-1) at 2C;the capacity decay rate is only 0.042% per cycle after 1000 cycles).Even under a high sulfur loading-E/S(electrolyte/sulfur)ratio of 5.1 mg·cm^(-2)-6 μl·mg^(-1),a high specific capacity of 723.7 mAh·g^(-1) is maintained after 60 *** study provides a new strategy for a multifunctional sulfur host that can effectively alleviate the shuttle effect of LiPSs and improve the utilization of sulfur active substances.

关键词： ZnO/ZnS heterostructure Lithium-sulfur batteries Density functional theory Anchor Conversion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：