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Immunological protection of small bowel by simultaneously transplanted liver graft in pigs

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Hepatobiliary & Pancreatic Diseases International 2009年第4期8卷 363-369页

作者： Yin, Zhen-Yu li, Ning Wang, Xiao-Ming Ni, Xiao-Dong Jiang, Feng li, You-Sheng li, jie-Shou Nanjing Univ Sch Med Jinling Hosp Inst Gen Surg Nanjing 210002 Peoples R China Xiamen Univ Zhongshan Hosp Dept Hepatobiliary Surg Xiamen 361004 Peoples R China

BACKGROUND: A simultaneously transplanted liver shields a bowel graft from immunologic attack in small animals, while the possible immuno-tolerance induced by the liver in liver and small bowel transplantation (LSBT) is uncertain in large animal models. To investigate the clinically suspected beneficial effect of the liver on small bowel allograft, we developed a new model of composite LSBT in the pig. METHODS: Seventy outbred long-white pigs were randomized into four groups. LSBT without immunosuppressive treatment (n=10, group A); LSBT with routine immunosuppressive treatment (n=10, group B); LSBT with a lower dose of immunosuppressive treatment (n=10, group C); and small bowel segment allotransplantation without immunosuppressive treatment (n=10, group D). RESULTS: There was no remarkable difference in survival time between groups A and D (10.33 vs. 12.89 days, P>0.05), but the initial time of acute rejection of the intestinal graft in group A was clearly delayed when compared to group D (8.22 vs. 4.33 days, P0.05), initial acute rejection time (25.40 vs. 22.13 days, P>0.05) or rejection score did not differ between groups B and C within one postoperative month. CONCLUSIONS: Compared to isolated segment small bowel allotransplantation, the intestinal graft in LSBT (group A) had a delayed initial time of acute rejection and a lower postoperative acute rejection score, and a lower dose of immunosuppressive treatment led to persistent graft immuno-tolerance in LSBT. Thus the simultaneously transplanted liver graft may reduce the risk of intestinal

关键词： liver transplantation small bowel transplantation porcine allotransplantation rejection immuno-tolerance

Microstructure and mechanical properties of lightweight AlCrTiV_(0.5)Cu_(x) high-entropy alloys

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Rare Metals 2022年第6期41卷 2016-2020页

作者： Zhen Peng Zai-Bin Luo bao-Wei li Jin-Feng li Heng-Wei Luan Jia-Lun Gu Yuan Wu Ke-Fu Yao School of Materials Science and Engineering Jiangsu Uni versityZhenjiang 212013China Institute of Materials China Academy of Engineering PhysicsMianyang 621908China School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Department of Mechanical Engineering City University of Hong KongHong Kong 999077China State Key Laboratory for Advanced Metals and Materials.University of Science and Technology Beijing Beijing 100083China

High-entropy alloys(HEAs)are an emerging and rapidly developing family of alloys with appealing properties such as lightweight HEAs with excellent mechanical *** this study,to obtain lightweight HEAs with exceptional hardness,we prepared AlCrTiV_(0.5)Cu_(x)(x=0,0.2,0.4,0.6,0.8 and 1.0,denoted as Cu_(0),Cu_(0.2),Cu_(0.4),Cu_(0.6),Cu_(0.8) and Cu_(1.0) alloys,respectively)HEAs and analyzed their microstructure and hardness.

关键词： alloys properties. Microstructure

Carbon footprint and carbon neutrality pathway of green tea in China

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Advances in Climate Change Research 2022年第3期13卷 443-453页

作者： Ming-bao HE Shi-Xiang ZONG Ying-Chun li Ming-Ming MA Xin MA Kuo li Xue HAN Ming-Yue ZHAO li-Ping GUO Yin-Long XU Institute of Environment and Sustainable Development in Agriculture Chinese Academy of Agricultural SciencesBeijing 100081China Beijing Key Laboratory for Forest Pest Control Beijing Forestry UniversityBeijing 100083China

With the rising popularity of the concept of“carbon neutralization”,low-carbon products are likely to gain more *** to this,green tea-an important beverage that is widely consumed in China-along with emissions from planting,processing,and use phase should be given ***,quantifying the carbon footprint(CF)of green tea is an essential task in developing the pathway to carbon *** this study,we quantified the CF and mitigation potential of green tea through life cycle assessment,after which we investigated the pathway toward carbon neutrality in 16 major tea-producing regions(except Hainan and Taiwan)in *** system boundary was divided into six subsystems from cradle to grave:cultivation,processing,transport,packaging,consumption,and *** results showed that the total carbon emissions of green tea reached 44.13 Mt CO_(2)eq in 2019,of which 43%came from consumption and 28%from *** were 18.78 Mt CO_(2)eq emissions from fertilizer production and application,while there was a 7.71 Mt CO_(2)eq carbon sink of tea *** average carbon intensity was 24.30 kg CO_(2)eq kg−1 tea,while Shandong and Guizhou ranked as the top two ***,Hubei,and Yunnan Provinces had the largest amounts of carbon emissions at 6.79,6.14,and 5.96 Mt CO_(2)eq,*** 2030,2050 and 2060,total carbon emissions would be reduced by 46%,63%,and 86%,respectively,under carbon neutrality assumption.A small amount of 6.14 Mt CO_(2)eq carbon emissions was retained to be offset by carbon trading or zero-carbon ***,the results indicate that adopting low-carbon fertilizers and clean energies will be a key entry point for carbon-neutral green tea.

关键词： Carbon neutrality Pathway life cycle assessment Carbon footprint Green tea China

Delay-aware reliable broadcast scheme based on power control for VANETs

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The Journal of China Universities of Posts and Telecommunications 2014年第1期21卷 26-35页

作者： GUO Wei-jie HUANG liu-sheng SUN Quan XU Hong-li ZHANG Hao-ran School of Computer Science and Technology University of Science and Technology of China Suzhou Institute for Advanced Study University of Science and Technology of China

In vehicular Ad-hoc network（VANET）, many multi-hop broadcast schemes are employed to widely propagate the warning messages among vehicles and the key is to dynamically determine the optimal relay vehicle for retransmission. In order to achieve reliable and fast delivery of warning messages, this paper proposes a delay-aware and reliable broadcast protocol（DR-BP） based on transmit power control technique. First, a comprehensive model is derived to evaluate the transmission in vehicle-to-vehicle communications. This model considers the wireless channel fading, transmission delay and retransmissions characters occurring in the physical layer/medium access control（PHY/MAC） layer. Then, a local optimal relay selection mechanism based on the above model is designed. In DR-BP scheme, only the vehicle selected as the optimal relays can forward warning messages and the transmit power is time-varying. Finally, extensive simulations verify the performance of DR-BP under different traffic scenarios. Simulation results show that DR-BP outperforms the traditional slotted 1-persistence（S1P） and flooding scheme in terms of packets delivery ratio and transmission delay.

关键词： transmission range delay-aware reliable power control relay selection VANET

Childhood Adversity Phenotypes and Risky Health Behaviors among Chinese Adolescents: Extending the Concept of Adversity

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Biomedical and Environmental Sciences 2022年第8期35卷 699-710页

作者： WANG Geng Fu YUAN Meng Yuan CHANG Jun jie li Yong Han SU Pu Yu Department of Maternal Child and Adolescent HealthSchool of Public HealthAnhui Medical UniversityHefei 230032AnhuiChina Key Laboratory of Population Health Across life Cycle(Anhui Medical University) Ministry of Education of the People's Republic of ChinaHefei 230032AnhuiChina NHC Key Laboratory of study onabnormal gametes and reproductive tract Hefei 230032AnhuiChina

ObjectiveTo present an approach to phenotyping ACEs and explore the association between ACEs and adolescent health risky behaviors based on the social context of *** Totally,5,726 adolescents aged 12-18 years were investigated about their ACEs in the family,peer,school,and personal domains and the occurrence of six types of risky health behaviors(i.e.,smoking,drinking,sexual intercourse,self-harm,and suicidal ideation and attempts).Latent class analysis(LCA)was used to explore the ACE *** Six latent classes of ACEs were identified,including low adversity,school adversity,school adversity and peer victimization,peer victimization,maltreatment and peer victimization,and high adversity,and associated with risky health behaviors in *** physically punished by a teacher,experiencing sexual abuse,and experiencing family trauma most strongly differentiated from the six AcE classes and were correlated with an increased risk for risky adolescent health *** study supports a positive association between ACEs and risky adolescent health *** victimization,school adversity and associated contexts need to be considered in future ACEstudies.

关键词： Adverse childhood experiences Adolescents Healthy risky behaviors Sexual abuse Peer victimization China

Raman Scattering of Zn_(1-x)Cd_(x)Se/ZnSe Strained Superlattices Under Hydrostatic Pressure

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Chinese Physics Letters 1998年第4期15卷 299-301页

作者： CHI Yuan-bin WANG li-zhong li Yan-mei ZOU Guang-tian li Wen-sen FAN Xi-wu YANG bao-jun State Key Laboratory of Superhard Materials Jilin UniversityChangchun 130023 Changchun Institute of Physics Chinese Academy of SciencesChangchun 130021

The Raman scattering in Zn_(0.74)Cd_(0.26)Se/ZnSe superlattices under hydrostatic pressures up to 4.53 GPa at room temperature has been *** pressure-dependences of the ZnSe-like LO-phonon(LO_(b))and the Zn_(0.74)Cd_(0.26)Se-like LO-phonon(LO_(w))have been *** 2.7GPa,the pressure-coefficients of both LO_(b) and LO_(w) phonon energies increase abruptly The 2LO_(w)-phonon resonance has been observed at 1.82GPa with 488.0nm excitation for the Zn_(0.75)Cd_(0.25)Se/ZnSe superlattices.

关键词： ZnSe scattering phonon

Gastrointestinal bleeding caused by syphilis: A case report

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World Journal of Clinical Cases 2021年第26期9卷 7909-7916页

作者： Dong-jie Sun Hai-Tao li Zhou Ye Bin-Bin Xu Da-Zhou li Wen Wang Department of Digestive Diseases 900th Hospital of Joint Logistics Support ForceFuzhou 350025Fujian ProvinceChina Fuzhou General Clinical Medical College Fujian Medical UniversityFuzhou 350025Fujian ProvinceChina Oriental Hospital Affiliated Xiamen UniversityXiamen 350025Fujian ProvinceChina

BACKGROUND Syphilis is a chronic,classic sexually transmitted disease caused by Treponema pallidum,which can invade almost all organs of the body and produce various symptoms and *** there are some cases of colorectal bleeding caused by syphilis,small intestinal bleeding caused by syphilis is still *** SUMMARY A 58-year-old man had experienced recurrent abdominal pain and melena for 3 *** gastroenteroscopy and computed tomography angiography examinations failed to find bleeding *** the same admission,multiple intestinal ulcers were found by capsule endoscopy,and syphilis was also *** a history of atrial fibrillation and chronic pancreatitis,he had undergone mitral valve replacement and tricuspid valvuloplasty for valvular heart *** anti-syphilis treatment,the melena and abdominal pain disappeared and his hemoglobin gradually *** is considered that gastrointestinal bleeding,chronic pancreatitis,atrial fibrillation,and heart valvular disease may have been caused by *** This case report found that syphilis can mimic systemic disease and cause intestinal *** addition,treatment of the disease requires both sexual partners to be ***,although syphilis is easy to treat,it is more important to consider that bleeding could be caused by syphilis.

关键词： Treponema pallidum Alimentary tract hemorrhage Small intestinal ulcer Gastrointestinal syphilis Infectious diseases Case report

Is combined extra-hepatic bile-duct resection justified for advanced gallbladder carcinoma?

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Gastroenterology Report 2019年第6期7卷 426-433,I0002页

作者： Jun-Ke Wang Wen-jie Ma Zhen-Ru Wu Qin Yang Hai-jie Hu Fei liu Fu-Yu li Department of Biliary Surgery West China HospitalSichuan UniversityChengduSichuanP.R.China Laboratory of Pathology West China HospitalSichuan UniversityChengduSichuanP.R.China

Background:Whether the extra-hepatic bile duct(EHBD)should be routinely resected for gallbladder carcinoma(GBC)remains *** current study aimed to determine the clinical impact of combined EHBD resection during curative surgery for advanced ***:In total,213 patients who underwent curative surgery for T2,T3 or T4 GBC were *** clinicopathological features were compared between the patients treated with EHBD resection and those without EHBD ***,univariable and multivariable Cox-proportional hazards regression models were used to identify risk factors for overall survival(OS).Results:Among the 213 patients identified,87(40.8%)underwent combined EHBD *** with patients without EHBD resection,patients with EHBD resection suffered more post-operative complications(33.3%vs.21.4%,P=0.046).However,the median OS of the EHBD resection group was longer than that of the non-EHBD resection group(25 vs.11 months,P=0.008).Subgroup analyses were also performed according to tumor(T)category and lymph-node *** median OS was significantly longer in the EHBD resection group than in the non-EHBD resection group for patients with T3 lesion(15 vs.7 months,P=0.002),T4 lesion(11 vs.6 months,P=0.021)or lymph-node metastasis(12 vs.7 months,P<0.001).No survival benefit of EHBD resection was observed in GBC patients with T2 lesion or without lymph-node metastasis.T category,lymph-node metastasis,margin status,pre-operative CA19-9 level and EHBD resection were identified as independent prognostic factors for OS of patients with advanced GBC(all P values<0.05).Conclusions EHBD resection can independently affect the OS in advanced *** GBC patients with T3 lesion,T4 lesion and lymph-node metastasis,combined EHBD resection is justified and may improve OS.

关键词： gallbladder carcinoma curative surgery extra-hepatic bile-duct resection overall survival

Effect of seepage-induced erosion on soil macropore structure

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Journal of Mountain Science 2023年第11期20卷 3402-3422页

作者： HUANG Wen-bo HUANG Da GAO Yi-kang liU Yang li Zhao MENG Qiu-jie School of Civil and Transportation Engineering Hebei University of TechnologyTianjin 300401China. College of Geology Engineering and Geomatics Chang’an UniversityXi’an 710054China.

Internal erosion is one of the important factors causing geological *** microstructure of soil can change with seepage erosion,resulting in changes in the hydraulic and mechanical properties of the *** evolution of seepage erosion is investigated with X-ray computed tomography(CT)in this *** change in macropore structure characteristics during the seepage erosion test is quantified and the influence of seepage erosion on soil deformation is ***,a pore network model(PNM)is established for the specimens and the evolution of the connected pore size characteristics is *** results show that the macropore structure is significantly affected by seepage erosion,especially in terms of the porosity and pore geometry *** changes in macropore structure characteristics are most obvious in the lower part of the *** influence of seepage erosion on the pore size distribution(PSD)and soil deformation is heterogeneous and closely dependent on the spatial location of the ***,seepage erosion enhances macropore connectivity and has a directional impact on macropore *** findings can provide a reference for the theoretical modeling and numerical simulation of the seepage erosion and improve the understanding of the seepage erosion evolution in engineering practice.

关键词： Seepage erosion Heterogeneity Macropore structure Pore size distribution Microstructure CT scanning