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Efficient micrometer-scale thick-film perovskite solar cells with superior stability

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Rare Metals 2024年第4期43卷 1647-1657页

作者： jian-Fei Hu Gang Chen Shun-zhang yu yue-Xin Lin Kai-yu Wang Zong-Wei Li guo-Dong zhang Teng-Fei Pan Ya-Jing Li Ming-jie Li Ying-Dong xia Yi-Fan Lv Yong-Hua Chen Key Laboratory of Flexible Electronics(KLoFE)and Institute of Advanced Materials(IAM) School of Flexible Electronics(Future Technologies)Nanjing Tech University(NanjingTech)Nanjing211816China Department of Applied Physics The Hong Kong Polytechnic UniversityHong Kong999077China Shenzhen Research Institute The Hong Kong Polytechnic UniversityShenzhen518057China Optics Valley Laboratory Hubei430074China

It is essential to enhance the thickness of the absorber layer for perovskite solar cells(PSCs)to improve device performance and reduce industry ***,thick perovskite films(>1μm)are difficult to be fabricated by employing traditional solvents,such as N,N-dimethylformamide(DMF),dimethyl sulfoxide(DMSO).Besides,it is a challenge to fabricate thick-film perovskite owing to the deteriorated surface morphology and serious defect ***,a simple method was reported to deposit uniform pinhole-free perovskite films with a thickness of more than 2μm utilizing the methylamine acetate(MAAc)ionic liquid as the *** with methylammonium chloride(MACl)as an additive,thick-film perovskite with~2μm in grain size and few grain boundaries(GBs)was prepared,which dramatically improved the perovskite crystal quality and enhanced carrier transport *** final PSCs exhibited a power conversion efficiency(PCE)of 20.16%.The device showed improved stability with 95%of its initial efficiency in a nitrogen environment over 5000 *** work provides an alternative strategy to produce extremely efficient and stable thick-film *** can be believed that this device has great potential in the application of large areas and laminated PSCs.

关键词： Perovskite solar cells Thick-film Stability Ionic liquid

A von-Neumann-like photonic processor and its application in studying quantum signature of chaos

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Light(Science & Applications) 2024年第4期13卷 672-681页

作者： Shang yu Wei Liu Si-Jing Tao Zhi-Peng Li Yi-Tao Wang Zhi-Peng Zhong Raj BPatel yu Meng yuan-Ze Yang zhao-An Wang Nai-jie guo xiao-Dong Zeng Zhe Chen Liang Xu Ning zhang xiao Liu Mu Yang Wen-Hao zhang Zong-Quan Zhou Jin-Shi Xu jian-Shun Tang Yong-jian Han Chuan-Feng Li Guang-Can guo CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China. CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China. Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China. Research Center for Quantum Sensing Zhejiang LabHangzhou 310000China. Quantum Optics and Laser Science Blackett LaboratoryImperial College LondonPrince Consort RdLondon SW72AZUK. Clarendon Laboratory Department of PhysicsOxford UniversityParks Road OX13PUOxfordUK

Photonic quantum computation plays an important role and offers unique *** decades after the milestone work of Knill-Laflamme-Milburn,various architectures of photonic processors have been proposed,and quantum advantage over classical computers has also been *** is now the opportune time to apply this technology to real-world ***,at current technology level,this aim is restricted by either programmability in bulk optics or loss in integrated optics for the existing architectures of processors,for which the resource cost is also a *** we present a von-Neumann-like architecture based on temporal-mode encoding and looped structure on table,which is capable of multimode-universal programmability,resource-efficiency,phasestability and *** order to illustrate these merits,we execute two different programs with varying resource requirements on the same processor,to investigate quantum signature of chaos from two aspects:the signature behaviors exhibited in phase space(13 modes),and the Fermi golden rule which has not been experimentally studied in quantitative way before(26 modes).The maximal program contains an optical interferometer network with 1694 freely-adjustable *** current state-of-the-art,our architecture stands as the most promising candidate for real-world applications.

关键词： quantum signature chaos

Neoadjuvant camrelizumab(an anti-PD-1 antibody)plus chemotherapy or apatinib(a VEGFR-2 inhibitor)for initially unresectable stage II–III non-small-cell lung cancer:a multicentre,two-arm,phase 2 exploratory study

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Signal Transduction and Targeted Therapy 2024年第7期9卷 3015-3023页

作者： Haoran xia Han zhang Zheng Ruan Huibiao zhang Liangdong Sun Hezhong Chen Yongxin Zhou Lele zhang Dongliang Bian Xinsheng Zhu Jing zhang Fenghuan Sun Huansha yu Nan Song xiaogang Liu yuming Zhu Haiping zhang Wenxin He jian Chen jie Yang guohan Chen Shiliang Xie Dongfang Tang xiaomiao zhang Liang Duan Deping zhao Qinchuan Li Peng zhang Gening jiang Department of Thoracic Surgery Shanghai Pulmonary HospitalTongji University School of MedicineShanghaiChina Department of Thoracic Surgery Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Thoracic Surgery Huadong Hospital Affiliated to Fudan UniversityShanghaiChina Department of Thoracic Surgery Changhai HospitalNaval Medical UniversityShanghaiChina Department of Thoracic-Cardiovascular Surgery Tongji HospitalTongji University School of MedicineShanghaiChina Central Laboratory Shanghai Pulmonary HospitalTongji University School of MedicineShanghaiChina Experimental Animal Center Shanghai Pulmonary HospitalTongji University School of MedicineShanghaiChina Department of Oncology Shanghai Pulmonary HospitalTongji University School of MedicineShanghaiChina Department of Thoracic Surgery Shanghai East HospitalTongji University School of MedicineShanghaiChina

This multicentre,two-arm,phase 2 study aimed to explore the efficacy and safety of neoadjuvant camrelizumab plus chemotherapy or apatinib in patients with initially unresectable stage II–III non-small-cell lung cancer(NSCLC).Eligible patients regardless of PD-L1 expression received neoadjuvant camrelizumab 200 mg and platinum-doublet chemotherapy every 3 weeks(arm A)or those with PD-L1-positive tumors received neoadjuvant camrelizumab and apatinib 250 mg once daily(arm B),for 2–4 cycles,followed by *** primary endpoint was major pathological response(MPR)*** patients in arm A and 21 in arm B were *** rates were 50.0%(15/30)in arm A and 42.9%(9/21)in arm B,with all patients achieving R0 *** these patients,the MPR and pathological complete response rates were both 20.0%(95%CI 4.3–48.1)in arm A and were 55.6%(95%CI 21.2–86.3)and 11.1%(95%CI 0.3–48.2)in arm B,*** corresponding objective response rates were 33.3%(95%CI 11.8–61.6)and 55.6%(95%CI 21.2–86.3).With a median follow-up of 22.4 months(95%CI 19.0–26.0),the median event-free survival was not reached(NR;95%CI 13.6-NR)in arm A and 16.8 months(95%CI 8.6-NR)in arm *** 3 or above treatment-related adverse events occurred in eight(26.7%)patients in arm A and three(14.3%)in arm *** analysis showed baseline TYROBP expression was predictive of treatment response in arm *** camrelizumab plus chemotherapy or apatinib exhibits preliminary efficacy and manageable toxicity in patients with initially unresectable stage II–III NSCLC.

关键词： Surgery chemotherapy treatment

10B-doped MCP detector developed for neutron resonance imaging at Back-n white neutron source

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Nuclear Science and Techniques 2024年第8期35卷 58-68页

作者： Qiang Li Li‑Jiao Wang Jing‑yu Tang xiang‑Biao Qiu Zhen Chen Mao‑yuan zhao Chang‑Jun Ning Kai Pan Wei Xu Tao Li Su‑Peng Lu Han Yi Rui‑Rui Fan Chang‑Qing Feng Rong zhang xiao‑Yang Sun Qi An Hao‑Fan Bai jiang‑Bo Bai jie Bao Ping Cao Qi‑Ping Chen Yong‑Hao Chen Zeng‑Qi Cui An‑Chuan Fan Fan‑Zhen Feng Min‑Hao Gu Chang‑Cai Han Zi‑jie Han guo‑Zhu He Yong‑Cheng He Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei jiang Zhi‑jie jiang Zheng‑Yao Jin Ling Kang Bo Li Gong Li xiao Li Yang Li jie Liu Rong Liu Shu‑Bin Liu Yi‑Na Liu Guang‑yuan Luan jie Ren Zhi‑Zhou Ren Xi‑Chao Ruan zhao‑Hui Song Kang Sun Zhi‑Xin Tan Sheng‑Da Tang Jin‑Cheng Wang Peng‑Cheng Wang zhao‑Hui Wang Zhong‑Wei Wen xiao‑Guang Wu Xuan Wu Cong xia Yong‑Ji yu guo‑Hui zhang Hang‑Chang zhang Lin‑Hao zhang Qi‑Wei zhang xian‑Peng zhang yu‑Liang zhang yue zhang Zhi‑Yong zhang Zhi‑Hao Zhou Ke‑Jun Zhu Chong Zou Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China North Night Vision Science and Technology(Nanjing)Research Institute Co.Ltd Nanjing 211106China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China China Academy of Engineering Physics Institute of Nuclear Physics and ChemistryMianyang 621900China USTC archaeometry lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China China Shipbuilding Trading Co. LtdBeijing 100044China

Neutron resonance imaging(NRI)has recently emerged as an appealing technique for neutron *** complexity surpasses that of conventional transmission imaging,as it requires a high demand for both a neutron source and ***,the progression of NRI technology has been sluggish since its inception in the 1980s,particularly considering the limited studies analyzing the neutron energy range above *** white neutron source(Back-n)at the China Spallation Neutron Source(CSNS)provides favorable beam conditions for the development of the NRI technique over a wide neutron energy range from eV to ***-sensitive microchannel plates(MCP)have emerged as a cutting-edge tool in the field of neutron detection owing to their high temporal and spatial resolutions,high detection efficiency,and low *** this study,we report the development of a 10B-doped MCP detector,along with its associated electronics,data processing system,and NRI experiments at the *** heavy elements such as gold,silver,tungsten,and indium can be easily identified in the transmission images by their characteristic resonance peaks in the 1–100 eV energy range;the more difficult medium-weight elements such as iron,copper,and aluminum with resonance peaks in the 1–100 keV energy range can also be *** particular,results in the neutron energy range of dozens of keV(Aluminum)are reported here for the first time.

关键词： Neutron resonance imaging 10B doped MCP detector White neutron source Sample nuclide identification

Characterization of a pangolin SARS-CoV-2-related virus isolate that uses the human ACE2 receptor

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Science China(Life Sciences) 2024年第7期67卷 1502-1513页

作者： Luo-yuan xia Xue-Feng Wang xiao-Ming Cui Yi-Ming zhang Zhen-Fei Wang En-Tao Li Chang-Fa Fan Ke Song yuan-guo Li Run-Ze Ye Fang-Xu Li Dai-yun Zhu jie zhang Zhuang-Zhuang Shi Ming-Zhu zhang Liang-Jing Li Shi-Jing Shen Song Jin Ya-Wei zhang Wei-Guang Fu Lin zhao Wen-Hao Wang Tie-Cheng Wang You-Chun Wang Jia-Fu jiang Yan-Ling Hu Na Jia yu-Wei Gao Wu-Chun Cao Institute of EcoHealth School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012China Changchun Veterinary Research Institute Changchun 130122China State Key Laboratory of Pathogen and Biosecurity Beijing Institute of Microbiology and EpidemiologyBeijing 100071China Division of Animal Model Research Institute for Laboratory Animal ResourcesNational Institutes for Food and Drug ControlBeijing 102629China National Institutes for Food and Drug Control Beijing 102629China Life Sciences Institute Guangxi Medical UniversityNanning 530020China College of Life Sciences Shandong Normal UniversityJinan 250014China Research Unit of Discovery and Tracing of Natural Focus Diseases Chinese Academy of Medical SciencesBeijing 100071China

Various SARS-CoV-2-related coronaviruses have been increasingly identified in pangolins,showing a potential threat to *** we report the infectivity and pathogenicity of the SARS-CoV-2-related virus,PCoV-GX/P2V,which was isolated from a Malayan pangolin(Manis javanica).PCoV-GX/P2V could grow in human hepatoma,colorectal adenocarcinoma cells,and human primary nasal epithelial *** replicated more efficiently in cells expressing human angiotensin-converting enzyme 2(hACE2)as SARS-CoV-2 *** intranasal inoculation to the hACE2-transgenic mice,PCoV-GX/P2V not only replicated in nasal turbinate and lungs,but also caused interstitial pneumonia,characterized by infiltration of mixed inflammatory cells and multifocal alveolar *** population immunity established by SARS-CoV-2 infection and vaccination may not protect people from PCoV-GX/P2V *** findings further verify the hACE2 utility of PCoV-GX/P2V by in vivo experiments using authentic viruses and highlight the importance for intensive surveillance to prevent possible cross-species transmission.

关键词： pangolin SARS-CoV-2-related virus infectivity pathogenicity human cell lines human ACE2 receptor hACE2-transgenic mice

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番茄苗期叶位色素含量高光谱检测及可视化研究

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光谱学与光谱分析 2024年第2期44卷 386-391页

作者：赵建贵王国梁张宇赵丽洁陈宁王文俊杜慧玲李志伟山西农业大学农业工程学院山西太谷030801 山西农业大学谷子研究所山西长治046000 山西农业大学基础部山西太谷030801

叶片色素含量是表征作物栽培基质营养元素和生理状态的重要指标;快速、精准获取色素含量及叶位分布规律是设施农业水肥精准化管理的基础。以番茄苗期不同叶位叶绿素a(Chla)、叶绿素b(Chlb)、叶绿素(Chll)和类胡萝卜素(Caro)为研究指标,... 详细信息

叶片色素含量是表征作物栽培基质营养元素和生理状态的重要指标;快速、精准获取色素含量及叶位分布规律是设施农业水肥精准化管理的基础。以番茄苗期不同叶位叶绿素a(Chla)、叶绿素b(Chlb)、叶绿素(Chll)和类胡萝卜素(Caro)为研究指标,用营养液配制10个氮素浓度;根据叶片位置摘取1710片(285个样本)用于可见光-近红外高光谱采集;运用卷积平滑(S-G)、标准正态变量变换(SNV)和多元散射校正(MSC)对光谱数据预处理。首先采用竞争自适应加权算法(CARS)对特征波段“粗”提取,然后利用迭代和保留信息变量算法(IRIV)判断“粗”提取波段的重要性,并对强弱波段组逆向消除“精”提取最优波段集合,建立偏最小二乘回归(PLSR)模型。结果表明:(1)营养液氮素浓度为302.84 mg·L^(-1),叶片色素含量最大,且高浓度的抑制作用高于低浓度,叶位色素含量呈上叶位>中叶位>低叶位分布规律;(2)采用CARS-IRIV-PLSR算法“粗-精”特征波段筛选策略分别对Chla、Chlb、Chll和Caro提取了4、4、10和11条特征波段,其Rp为0.7722、0.7321、0.8471和0.8587;(3)结合最优模型色素定量反演图像可视化表达,Chla、Chlb和Chll分布规律一致,而Caro与Chll分布规律相反,该结论与植物生理特征和测定结果相吻合。采用高光谱成像技术能够实现对叶片色素含量进行无损检测及可视化表达,为设施农业植物叶片色素分布、养分亏缺和施肥决策等提供数据支撑和理论依据。

关键词：高光谱叶位色素含量特征波段可视化

Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China:A national multicenter survey of 35,566 individuals

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan Liu Rui-xia Ma xian-Bao Cao Hua zhang Shui-Hong Zhou Wei-Hong jiang Yan jiang Jing-Wu Sun Qin-Tai Yang Xue-Zhong Li Ya-Nan Sun Li Shi Min Wang Xi-Cheng Song Fu-Quan Chen xiao-Shu zhang Hong-Quan Wei Shao-Qing yu Dong-Dong Zhu Luo Ba Zhi-Wei Cao Xu-Ping xiao Xin Wei Zhi-Hong Lin Feng-Hong Chen Chun-Guang Shan Guang-Ke Wang Jing Ye Shen-Hong Qu Chang-Qing zhao Zhen-Lin Wang Hua-Bin Li Feng Liu xiao-Bo Cui Sheng-Nan Ye Zheng Liu yu Xu xiao Cai Wei Huang Ru-Xin zhang yu-Lin zhao guo-Dong yu Guang-Gang Shi Mei-Ping Lu Yang Shen yu-Tong zhao Jia-Hong Pei Shao-Bing Xie Long-Gang yu Ye-Hai Liu Shao-Wei Gu yu-Cheng Yang Lei Cheng jian-Feng liu Graduate School of Beijing University of Chinese Medicine BeijingChina Department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina Department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina Department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina Department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina Department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina Department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and Prevention LanzhouChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 28,2022,and February 21,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.29 and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12 days,respectively,with 0.5%of patients having symptoms lasting for more than 28 *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2 virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2 vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

利用质子能损诊断部分电离等离子体靶中的束缚电子密度

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物理学报 2024年第7期73卷 144-151页

作者：陈燕红王昭周泽贤陶科伟金雪剑史路林王国东喻佩雷瑜吴晓霞程锐杨杰中国科学院近代物理研究所兰州730000 中国科学院大学北京100049 西北师范大学物理与电子工程学院兰州730070 先进能源科学与技术广东省实验室惠州516000

部分电离等离子体是惯性约束聚变燃料及天体等离子体中的重要组成部分,该等离子体的输运及流体力学等性质受到束缚电子的显著影响,然而当前基于光谱学的技术手段难以对其进行高精度诊断.本文基于中国科学院近代物理研究所低能离子束与... 详细信息

部分电离等离子体是惯性约束聚变燃料及天体等离子体中的重要组成部分,该等离子体的输运及流体力学等性质受到束缚电子的显著影响,然而当前基于光谱学的技术手段难以对其进行高精度诊断.本文基于中国科学院近代物理研究所低能离子束与等离子体相互作用实验平台,精确测量了100 ke V质子束穿过部分电离氢等离子体靶后的能损,该能损是质子同靶区内自由电子与束缚电子碰撞共同作用的结果.利用已有的能损理论模型,结合激光干涉诊断获得的自由电子密度信息,最终得到了部分电离氢等离子体靶中沿离子路径上的束缚电子密度,并给出了该等离子体的离化度参数.该离子束诊断技术具有在线、原位、分辨率高等优势,为解决部分电离等离子体内部束缚电子密度的诊断问题提供了新的途径.

关键词：束缚电子密度质子能损自由电子密度离化度

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静脉内平滑肌瘤病57例临床分析

中国实用妇科与产科杂志 2024年第6期40卷 653-656页

作者：苏克张也蔡玉洁张艳艳赵孟玲郭瑞霞郑州大学第一附属医院妇科河南郑州450052 河南省妇科肿瘤生育力保护工程研究中心河南郑州450052

目的探讨静脉内平滑肌瘤病(intravenous leiomyomatosis,IVL)的临床特点、治疗方法和预后。方法回顾性分析郑州大学第一附属医院2013年1月至2023年1月收治的病理确诊为IVL57例患者的临床资料和随访情况。结果患者年龄(45.2±5.5)岁。有... 详细信息

目的探讨静脉内平滑肌瘤病(intravenous leiomyomatosis,IVL)的临床特点、治疗方法和预后。方法回顾性分析郑州大学第一附属医院2013年1月至2023年1月收治的病理确诊为IVL57例患者的临床资料和随访情况。结果患者年龄(45.2±5.5)岁。有子宫肌瘤剔除史11例(19.3%),有子宫切除史6例(10.5%)。常见的临床症状包括:经量增多、经期延长30例(52.6%),腹胀11例(19.3%),心悸、胸闷6例(10.5%),下肢水肿5例(8.8%)。根据肿瘤侵袭范围将IVL分为4期,Ⅰ期:肿瘤局限于盆腔33例;Ⅱ期:肿瘤扩展至腹腔16例;Ⅲ期:肿瘤侵袭至心脏7例;Ⅳ期:肿瘤侵袭至肺动脉1例。全部患者均行手术治疗,术后定期随访,3例患者术后复发,其中1例再次手术。结论IVL好发于生育期和围绝经期女性,缺乏特异性临床症状。治疗方法以手术治疗为主,要根据病变累及范围决定手术方案,术后需定期复查,严密随访。

关键词：静脉内平滑肌瘤病子宫平滑肌瘤子宫肿瘤血管肿瘤