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Asian Pacific Journal of Tropical Medicine 2016年第5期9卷 456-459页

作者： Ying Kuang Ying-jie nie Central Lab Guizhou Provincial People's Hospital

Objective: To study the regulatory effects of miR-21 on breast cancer cell line proliferation and invasion as well as the downstream target genes. Methods: Breast cancer cell lines MCF-7 were cultured and transfected with miR-21 mimics and the corresponding negative control mimics(NC mimics), and then MTS kits were used to detect cell viability. Transwell experiment was used to detect cell invasion ability, and fluorescence quantitative PCR was used to detect the expression of proliferation and invasion-related genes in cells. Results: 24 h after transfection of miR-21 mimics and NC mimics, cell OD value and the number of invasive cells of miR-21 group were significantly higher than those of NC group, and m RNA contents of PDCD-4, Fas L, PTEN, Rho B, Maspin, TIMP3 and RECK in cells were significantly lower than those of NC group. Conclusion: miR-21 can promote the proliferation and invasion of breast cancer cell lines, and its downstream target genes include PDCD-4, Fas L, PTEN, Rho B, Maspin, TIMP3 and RECK.

关键词： Breast cancer Micro RNA Proliferation Invasion

Controlled Secure Quantum Dialogue Using a Pure Entangled GHZ States

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Communications in Theoretical Physics 2007年第5X期48卷 841-846页

作者： XIA Yan SONG jie nie Jing SONG He-Shan School of Physics and Optoelectronic Technology Dalian University of Technology Dalian 116024 China

We present a controlled secure quantum dialogue protocol using a non-maximally （pure） entangled Greenberger-Horne-Zeibinger （GHZ） states at first, and then discuss the requirements for a real quantum dialogue. We show that the authorized two users can exchange their secret messages after purifying the non-maximally entangled GHZ states quantum channel unconditionally securely and simultaneously under the control of a third party.

关键词： controlled secure quantum dialogue eavesdropper non-maximally entangled GHZ state

A lock-free approach to parallelizing personalized PageRank computations on GPU

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Frontiers of Computer Science 2023年第1期17卷 219-220页

作者： Zhigang WANG Ning WANG jie nie Zhiqiang WEI Yu GU Ge YU Faculty of Information Science&Engineering Ocean University of ChinaQingdao 266100China School of Computer Science and Engineering Northeastern UniversityShenyang 110819China

1 Introduction Personalized PageRank(PPR)is a classic topology-based proximity measure and it is most widely computed by Forward *** is,given a starting vertex in graph,it iteratively computes the importance score of any vertex in with respect to,and then broadcasts the new score as messages to’s neighboring *** process converges until all scores hold ***,Graphical Processing Units(GPU)with massive threads has been extensively used to parallelize such compute-intensive *** yields performance improvement but also involves two atomic locks for *** locks are practically inefficient and become a new performance *** paper proposes a separation technique to partially eliminate atomic protections,termed as Lightweight Forward Push.A Forward Pull solution is further devised to support lock-free PPR computations but also causes useless *** best performance,a new Hybrid Framework is then designed to adaptively balance locking costs and reading costs.

关键词： PageRank GPU Push

Study on the transverse structures across Taiwan Strait

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Science China Earth Sciences 2002年第12期45卷 1114-1126页

作者： MA Zongjin (马宗晋) WANG Chien-Ying (王乾盈) XU jie (徐杰) nie Fengjun (聂逢君) ZHANG Jin (张进) Institute of Geology China Seismological Bureau Beijing 100029 China Institute of Geophysics National Central University Taibei 32054 China Institute of Geology China Seismological Bureau Beijing 100029 China Institute of Geology China Seismological Bureau Beijing 100029 China Institute of Geology China Seismological Bureau Beijing 100029 China

The mountain ranges are almost NE- or NNE-trending in mainland and Taiwan island across the strait. But a number of correspondent transverse structures across Taiwan Strait have been identified on the basis of morphology, surface structure, deep seismic survey and gravity field etc. Moreover, it is inferred from the square or/and rectangular shape of the isoseist maps of 8 M≥6 earthquakes occurring in the western foothill plain of Taiwan that there is an apparent segmentation of the Taiwan Island along the N-S orientation. This has been verified from the GPS's results of the ground motions measured during the Chi-Chi earthquake in 1999. As a matter of fact, the transverse structures within the Taiwan Island could be correlated with more salient NW- and EW-trending structures in the mainland of Fujian than in Taiwan. The investigation of the transverse structures across Taiwan Strait is conducive to realizing the geology within the strait. Hence, the tectonic sketch map of the strait as well as mainland and island drawn in this context shows NW- and EW-trending structures for the study area.

关键词： Taiwan Strait, transverse structure, Chi-Chi earthquake, GPS.

An efficient data-driven global sensitivity analysis method of shale gas production through convolutional neural network

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Petroleum Science 2024年第4期21卷 2475-2484页

作者： Liang Xue Shuai Xu jie nie Ji Qin Jiang-Xia Han Yue-Tian Liu Qin-Zhuo Liao State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China Department of Oil-Gas Field Development Engineering College of Petroleum EngineeringChina University of Petroleum(Beijing)Beijing102249China Chuanqing Drilling Engineering Co.Ltd. China National Petroleum CorporationChengdu610051SichuanChina

The shale gas development process is complex in terms of its flow mechanisms and the accuracy of the production forecasting is influenced by geological parameters and engineering ***,to quantitatively evaluate the relative importance of model parameters on the production forecasting performance,sensitivity analysis of parameters is *** parameters are ranked according to the sensitivity coefficients for the subsequent optimization scheme design.A data-driven global sensitivity analysis(GSA)method using convolutional neural networks(CNN)is proposed to identify the influencing parameters in shale gas *** CNN is trained on a large dataset,validated against numerical simulations,and utilized as a surrogate model for efficient sensitivity *** approach integrates CNN with the Sobol'global sensitivity analysis method,presenting three key scenarios for sensitivity analysis:analysis of the production stage as a whole,analysis by fixed time intervals,and analysis by declining *** findings underscore the predominant influence of reservoir thickness and well length on shale gas ***,the temporal sensitivity analysis reveals the dynamic shifts in parameter importance across the distinct production stages.

关键词： Shale gas Global sensitivity Convolutional neural network Data-driven

Verification of a self-developed CFD-based multi-physics coupled code MPC-LBE for LBE-cooled reactor

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Nuclear Science and Techniques 2021年第5期32卷 84-100页

作者： Zhi-Xing Gu Qing-Xian Zhang Yi Gu Liang-Quan Ge Guo-Qiang Zeng Mu-Hao Zhang Bao-jie nie College of Nuclear Technology and Automation Engineering Chengdu University of TechnologyChengdu 610059China Sino-French Institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China

To perform an integral simulation of a pool-type reactor using CFD code,a multi-physics coupled code MPC-LBE for an LBE-cooled reactor was proposed by integrating a point kinetics model and a fuel pin heat transfer model into self-developed CFD *** code verification,a code-to-code comparison was employed to validate the CFD ***,a typical BT transient benchmark on the LBE-cooled XADS reactor was selected for verification in terms of the integral or system *** on the verification results,it was demonstrated that the MPC-LBE coupled code can perform thermal-hydraulics or safety analyses for analysis for processes involved in LBE-cooled pool-type reactors.

关键词： LBE-cooled pool-type reactor Computational fluid dynamics Multi-physics coupling code Safety analysis code Verification

Gastrotracheal fistula:Treatment with a covered self-expanding Y-shaped metallic stent

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World Journal of Gastroenterology 2015年第3期21卷 1032-1035页

作者： Fei Wang Hong Yu Ming-Hui Zhu Quan-Peng Li Xian-Xiu Ge Jun-jie nie Lin Miao Institute of Digestive Endoscopy and Medical Center for Digestive Diseases Second Affiliated Hospital of Nanjing Medical University Department of Gastroenterology People’s Hospital of Jingjiang

A 67-year-old man had a sev-ere cough and pulmonary infection for 1 wk before seeking evaluation at our *** had undergone esophagectomy with gastric pull-up and radiotherapy for esophageal cancer 3 years *** admission to our hospital,gastroscopy and bronchoscopy revealed a fistulous communication between the posterior tracheal wallnear the carina and the upper residual *** measured the diameter of the trachea and bronchus and determined the site and size of the fistula using multislice computed tomography and gastroscopy.A covered self-expanding Y-shaped metallic stent was implanted into the trachea and ***,the fistula was closed *** patient tolerated the stent well and had good palliation of his symptoms.

关键词： Gastrotracheal fistula Y-shaped metallic stent Eso

Study on inhomogeneous cooling behavior of extruded profile with unequal and large thicknesses during quenching using thermo-mechanical coupling model

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Transactions of Nonferrous Metals Society of China 2020年第5期30卷 1211-1226页

作者： Zhi-wen LIU jie YI Shi-kang LI Wen-jie nie Luo-xing LI Guan WANG School of Mechanical Engineering University of South ChinaHengyang 421001China State Key Laboratory of Advanced Design and Manufacture for Vehicle Body Hunan UniversityChangsha 410082China College of Mechanical Engineering Ningxia UniversityYinchuan 750021China

The interfacial heat transfer coefficient between hot profile surface and cooling water was determined by using inverse heat conduction model combined with end quenching experiment. Then, a Deform-3 D thermo-mechanical coupling model for simulating the on-line water quenching of extruded profile with unequal and large thicknesses was developed. The temperature field, residual stress field and distortion of profile during quenching were investigated systematically. The results show that heat transfer coefficient increases as water flow rate increases. The peak heat transfer coefficient with higher water flow rates appears at lower interface temperatures. The temperature distribution across the cross-section of profile during quenching is severe nonuniform and the maximum temperature difference is 300 ℃ at quenching time of 3.49 s. The temperature difference through the thickness of different parts of profile first increases sharply to a maximum value, and then gradually decreases. The temperature gradient increases obviously with the increase of thickness of parts. After quenching, there exist large residual stresses on the inner side of joints of profile and the two ends of part with thickness of 10 mm. The profile presents a twisting-type distortion across the cross-section under non-uniform cooling and the maximum twisting angle during quenching is 2.78°.

关键词： aluminum profile unequal and large thicknesses water quenching heat transfer coefficient thermo-mechanical coupling model

Framework for distributed video surveillance in heterogeneous environment

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通讯和计算机（中英文版） 2009年第2期6卷 25-28页

作者： FU Xiang ZENG jie-xian nie Yun-feng School of Computer Nanchang Hangkong University Nanehang 330063 China

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压水堆核电厂核岛机械设备在役检查规则研究

核科学与工程 2016年第4期36卷 449-458页

作者：蔡杰聂勇核动力运行研究所湖北武汉430223

压水堆核电厂核岛机械设备在役检查规则研究是修订和编制我国相关核电在役检查标准的基础和前提。本文简介了在役检查规则研究目标、方法、主要内容和结果以及在役检查规则制定依据,简述了规则研究相关主要问题的处理方法和结果,对比分... 详细信息

压水堆核电厂核岛机械设备在役检查规则研究是修订和编制我国相关核电在役检查标准的基础和前提。本文简介了在役检查规则研究目标、方法、主要内容和结果以及在役检查规则制定依据,简述了规则研究相关主要问题的处理方法和结果,对比分析了依据研究结果编制的NB/T 20312标准与EJ/T 1041标准在役检查规则的主要不同点,给出了准确理解和正确应用NB/T 20312标准有关在役检查规则的提示和说明,为有效应用该标准在役检查规则提供重要参考。

关键词：压水堆标准在役检查机械设备规则研究