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Frontiers of Environmental Science & Engineering 2016年第3期10卷 458-466页

作者： Nanli QIAO Xin ZHANG Chi HE Yang LI Zhongshen ZHANG jie cheng Zhengping HAO Department of Environmental Nano-materials and Technologies Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China Department of Environmental Science and Engineering School of Energy and Power Engineering Xi'an Jiaotong University Xi'an 710049 China

A series of hierarchical macro-/mesoporous silica supports （MMSs） were successfully synthesized using dual-templating technique employing polystyrene （PS） spheres and the Pluronic P123 surfactant. Pd was next loaded on the hierarchical silica supports via colloids precipitation method. Physicochemical properties of the synthesized samples were characterized by various techniques and all catalysts were tested for the total oxidation of o-xylene. Among them, the Pd/MMS-b catalyst with tetraethoxysilane/polystyrene weight ratio of 1.0 exhibited superior catalytic activity, and under a higher gas hourly space velocity （GHSV） of 70000 h^-1, the 90% conversion of o-xylene has been obtained at around 200℃. The BET and SEM results indicated that Pd/MMS- b catalyst possesses high surface area and large pore volume, and well-ordered, interconnected macropores and 2D hexagonally mesopores hybrid network. This novel ordered hierarchical porous structure was highly beneficial to the dispersion of active sites Pd nanoparticles with less aggregation, and facilitates diffusion of reactants and products. Furthermore, the Pd/MMS-b catalyst possessed good stability and durability.

关键词： hierarchical macro-/mesoporous silica palladium VOCs catalytic oxidation

吲哚布芬联合氯吡格雷对急性心肌梗死患者PCI术后疗效的临床研究

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中国临床药理学杂志 2024年第4期40卷 497-500页

作者：程辉彭杰成伍万仕胡兴兵苏家凤安徽医科大学附属安庆第一人民医院心血管内科安徽安庆246000

目的探讨吲哚布芬联合氯吡格雷对急性心肌梗死(AMI)患者经皮冠状动脉介入治疗(PCI)术后疗效及血小板活性和凝血功能的影响。方法将AMI患者按照队列法分为试验组和对照组,对照组接受阿司匹林0.1 g(qd)+氯吡格雷75 mg(qd)口服治疗;试验... 详细信息

目的探讨吲哚布芬联合氯吡格雷对急性心肌梗死(AMI)患者经皮冠状动脉介入治疗(PCI)术后疗效及血小板活性和凝血功能的影响。方法将AMI患者按照队列法分为试验组和对照组,对照组接受阿司匹林0.1 g(qd)+氯吡格雷75 mg(qd)口服治疗;试验组接受吲哚布芬片0.1 g(bid)+氯吡格雷75 mg(qd)口服治疗,2组均服用1个月。比较2组疗效、治疗前后血小板计数(PLT)、平均血小板体积(MPV)、凝血酶原时间(PT)、纤维蛋白原(FIB)、D-二聚体(D-D)和药物不良反应发生率。结果试验组38例,对照组43例。治疗后,试验组和对照组的疗效分别为97.37%和86.05%,在统计学上差异无统计学意义(P>0.05)。治疗后,试验组和对照组PLT分别为(167.89±43.62)×10^(9)·L^(-1)和(183.73±49.81)×10^(9)·L^(-1);MPV分别为(11.86±2.31)和(10.97±2.16)fl;FIB分别为(2.53±0.61)和(2.78±0.72)g·L^(-1);D-D分别为(0.20±0.06)和(0.22±0.07)mg·L^(-1);PT分别为(12.82±2.35)和(12.26±2.28)s,在统计学上差异均无统计学意义(均P>0.05)。试验组和对照组的药物不良反应发生率分别为2.63%和11.63%,在统计学上差异有统计学意义(P<0.001)。结论吲哚布芬联合氯吡格雷的治疗效果与阿司匹林基本一致,均具有较好的抗血小板聚集作用,且吲哚布芬安全性更高,推荐作为AMI患者PCI术后的用药方案。

关键词：吲哚布芬氯吡格雷急性心肌梗死经皮冠状动脉介入治疗临床疗效血小板活性凝血功能

两种从场地调查数据中分离土壤环境背景数据方法的比较

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生态与农村环境学报 2024年第5期40卷 718-728页

作者：吴运金夏菲洋杨敏胡洁潘成杰邓绍坡王荐生态环境部南京环境科学研究所江苏南京210042 江苏滨海经济开发区沿海工业园管委会江苏盐城224555

地块土壤环境背景值在我国土壤环境管理中具有重要作用,土壤环境背景含量数据可采用间接方法从土壤污染状况调查数据中分离获得。采用稳健正态概率Q-Q图法和标准阈值法两种间接方法,从研究案例数据和模拟数据中分离土壤环境背景数据,并... 详细信息

地块土壤环境背景值在我国土壤环境管理中具有重要作用,土壤环境背景含量数据可采用间接方法从土壤污染状况调查数据中分离获得。采用稳健正态概率Q-Q图法和标准阈值法两种间接方法,从研究案例数据和模拟数据中分离土壤环境背景数据,并对两种方法的有效性和适用性进行比较分析。案例地块土壤钴(Co)含量数据呈现双峰分布,来源于两个不同总体。模拟数据M_(1)和M_(2)来源于背景数据(B)和非背景数据(N_(1)或N_(2)),M_(1)由B和N_(1)组成,两者之间重叠较多,M_(2)由B和N_(2)组成,两者之间重叠较少。研究结果显示,对于案例地块数据,利用稳健正态Q-Q图法和标准阈值法分离出的土壤环境背景数据之间差异较小,且与采用背景参考区法获得的土壤环境背景数据具有相似的统计特征。对于模拟数据,采用标准阈值法和稳健Q-Q图法都可以有效地从模拟数据M_(1)和M_(2)中分离出背景数据,两种方法分离出的背景数据之间及其与B之间均没有显著差异,且模拟数据的不同重叠程度对分离背景数据的影响较小。但是由于采用标准阈值法分离出的背景数据与B更相近,且方法简单易操作,更适用于土壤环境背景数据的分离。该研究可为地块土壤环境背景数据的获取提供方法上的借鉴。

关键词：土壤环境背景稳健正态概率Q-Q图法标准阈值法分离

Response of Escherichia coli to hydrogen nanobubbles:an in vitro evaluation using synchrotron infrared spectroscopy

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2021年第11期22卷 966-970页

作者： Jinfang LU Jin ZHENG Yadi WANG jie cheng Xueling LI Jun HU Bin LI Junhong Lü CAS Key Laboratory of Interfacial Physics and Technology Shanghai Institute of Applied PhysicsChinese Academy of SciencesShanghai 201800China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201203China College of Pharmacy Binzhou Medical UniversityYantai 264003China National Engineering Research Center for Nanotechnology Shanghai 201318China University of Chinese Academy of Sciences Beijing 100049China

Hydrogen(H2)-rich water,an apparent source of molecular H2,is an emerging functional drink with many purported benefits for human health(Yang et al.,2020;Ostojic,2021).The preventive and therapeutic effects of H2 on various pathological processes have been intensively investigated in numerous clinical trials;it is commonly believed that the beneficial effects are mainly attributed to its selective antioxidant and antiinflammatory properties(Lee et al.,2015;Ohta,2015;LeBaron et al.,2019;Qiu et al.,2020).In recent years,a handful of rodent studies revealed that exogenous H2 can afifect the gut microbiota(Sha et al.,2018;Valdes et al.,2018).

关键词： hydrogen attributed apparent

糖转运蛋白SlSWEET12c负向调控番茄对细菌性叶斑病的抗性

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园艺学报 2024年第2期51卷 321-334页

作者：邢亚男程杰刘欣吕书文吴媛媛姜晶沈阳农业大学园艺学院沈阳110866 辽宁省农业科学院蔬菜研究所沈阳110161

根据番茄表达数据库(http://ted.***.cornell.edu/cgi-bin/)及实时定量分析发现,糖转运蛋白(sugars will eventually be exported transporters)基因SlSWEET12c在番茄感病品种和抗病品种中表达差异最明显。以番茄(Solanum lycopersicum)栽培品种‘中蔬6号’为试材,获得了稳定遗传的SlSWEET12c沉默(RNAi)和过表达(OE)植株。进一步接种细菌性叶斑病病菌丁香假单胞菌(Pst DC3000)后,通过对叶片中细菌生长量、Fv/Fm变化,可溶性糖和淀粉含量、活性氧积累及防御酶活性和PR蛋白相关基因表达情况的分析,明确SWEET12c在番茄抵御PstDC3000过程中的作用。与野生型相比,RNAiSlSWEET12c植株接种Pst DC3000后叶片中的细菌生长量、病斑数明显减少,对Pst DC3000的抗性增强,而OE-SlSWEET12c的叶片发病更严重,细菌菌落数及褐色病斑数增多。RNAi-SlSWEET12c植株在接菌后蔗糖和淀粉含量明显高于野生型,活性氧积累少于野生型,防御酶(POD、SOD、APX)活性和PR蛋白相关基因(NPR1、PR1、PR2、PR5)表达明显升高,而OE-SlSWEET12c植株蔗糖和淀粉含量低于野生型,活性氧积累高于野生型,防御酶活性和PR蛋白相关基因表达明显低于野生型。以上结果表明SlSWEET12c通过影响叶片中糖分的组成,负向调控番茄对细菌性叶斑病的抗性。

关键词：番茄糖转运蛋白细菌性叶斑病 SlSWEET12c

Identification of three members of the Bmp family from yellow catfish Pelteobagrus fulvidraco and their transcriptional responses to a high fat diet

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Aquaculture and Fisheries 2021年第1期6卷 63-68页

作者： Zhipeng Tai Shicheng Ling jie cheng Xiaoying Tan Key Laboratory of Freshwater Animal Breeding Ministry of AgricultureFishery CollegeHuazhong Agricultural UniversityWuhan430070China

In this study,three members of the Bmp family were cloned and characterized in yellow catfish Pelteobagrus fulvidraco,including Bmp2a,Bmp4 and Bmp9.The predicted amino acid sequences of P.fulvidraco Bmp2a,Bmp4 and Bmp9 showed the characteristic domains of the Bmp family,including an N-terminal signal peptide,Arg-X-XArg site,TGF-β family signature and seven conserved cysteines,indicating that function is likely to have been conserved during evolution.mRNAs of the three Bmp genes had a variable level of expression in tissues.Compared to the control diet,a high fat diet tended to down-regulate the mRNA expression of Bmp2a,Bmp4 and Bmp9 in mesenteric fat,liver and ovary,while it tended to up-regulate their mRNA levels in muscle and kidney.The responses to dietary lipid status and the potential role in lipid metabolism have not previously been reported and reinforces the idea of their multiple functions.Our findings provide the first data about the potential role of the Bmp family in lipid metabolism in teleost.

关键词： Bmp family Gene characterization Tissue expression Pelteobagrus fulvidraco High fat diet

Suggestions on Curriculum Reform of Food Major in the Context of Educational Reform

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Agricultural Biotechnology 2023年第2期12卷 133-137页

作者： jie cheng Ruiqi CAO Lili JI Bo HOU Dayu LIU Jiamin ZHANG Meat Processing Key Laboratory of Sichuan Province College of Food and BioengineeringChengdu UniversityChengdu 610106China

The food major is an application-oriented major that involves a wide range of professional knowledge and disciplines,and provides applied talents with food production,inspection,and sales skills to the society.With the rapid development of society,the demand of social employers for talents also shows a diversified trend.For the cultivation of food professionals in the new era,it is necessary to improve their innovative spirit and practical ability,in order to adapt to the diverse development needs of society.Under the background of education reform,this paper briefly analyzed the teaching strategies of food major,and put forward specific reform suggestions,hoping to promote education reform to effectively promote the sustainable development of food major,and effectively improve the quality of education.

关键词： Education reform Food Major Teaching innovation Teaching methods

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超高速管道磁浮系统通道规划研究

铁道标准设计 2024年第2期68卷 1-6,14页

作者：张云娇王修华范丁元程婕中铁工程设计咨询集团有限公司北京100055 中国国际工程咨询有限公司北京100048

以超高速管道磁浮系统在我国通道规划布局研究为目的,通过对标民航、高铁两大高速运输系统的发展趋势和特征,深入剖析超高速管道磁浮系统的必要性和发展定位;同时,以我国综合立体交通规划纲要为依据,提出超高速低真空管道磁悬浮的“四... 详细信息

以超高速管道磁浮系统在我国通道规划布局研究为目的,通过对标民航、高铁两大高速运输系统的发展趋势和特征,深入剖析超高速管道磁浮系统的必要性和发展定位;同时,以我国综合立体交通规划纲要为依据,提出超高速低真空管道磁悬浮的“四阶段”发展战略:建设工程试验线、中短距离商业示范线、长距离快运通道和超高速交通管道系统网;采用“面、点、线”分析法通过人口分布、经济发展、城镇化格局、规划方向等因素研究路网通道构建。研究建议近期建设京津冀—长三角、京津冀—粤港澳、长三角—粤港澳、长三角—成渝,远期建设京津冀—成渝、粤港澳—成渝、京津冀—哈长、大陆桥、长三角—滇中通道,形成由9条通道组成的“钻石+放射”型规划方案,构建超级城市群两小时快速通达圈、相邻城市群一小时经济生活圈、区域性中心城市间半小时同城圈的超高速交通系统通道网络。

关键词：超高速磁浮系统通道规划高速铁路民航发展战略通达时效目标市场

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气动3-UPU型机器人位姿控制

液压与气动 2024年第6期48卷 56-64页

作者：刘昱陶春龙吕佳洋程杰北京石油化工学院信息工程学院北京102617

对于气动伺服系统而言,活塞的运动、参数时变以及建模的不确定都进一步增加了高精度位置控制的难度。针对气动3-UPU机器人系统建立三阶数学模型,为控制算法提供参考模型;提出基于自抗扰(Auto-disturbance Rejection Controller, ADRC)... 详细信息

对于气动伺服系统而言,活塞的运动、参数时变以及建模的不确定都进一步增加了高精度位置控制的难度。针对气动3-UPU机器人系统建立三阶数学模型,为控制算法提供参考模型;提出基于自抗扰(Auto-disturbance Rejection Controller, ADRC)的高精度位姿控制算法,以非线性PID为基础,结合跟踪微分器安排快速且平稳的过渡过程,将气缸内泄漏流量作为扰动设计扩张状态观测器,构建适用于高精度气动3-UPU机器人的ADRC控制器。结果表明:自抗扰控制器具有较强的鲁棒性,稳态控制精度约为0.45 mm, 0.2 Hz时动态跟踪均方误差小于10.0 mm。

关键词：位姿控制自抗扰 3-UPU机器人气动系统建模

Effects of electroacupuncture at Zusanli (ST 36) on neurons in the colonic myenteric plexus in rats with irritable bowel syndrome with constipation

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Neural Regeneration Research 2011年第33期6卷 2605-2609页

作者： Liting Zhu Zhonghan Li Bin Xu Chen Xia jie cheng Xiaoren Xiang Yi Zhu Department of Acupuncture and Massage Second Clinical College Nanjing University of Traditional Chinese Medicine Nanjing 210046 Jiangsu Province China National Key Laboratory of Acupuncture and Medicine of China Nanjing 210029 Jiangsu Province China Department of Acupuncture and Rehabilitation Jiangsu Province Chinese Medicine Hospital Nanjing 210029 Jiangsu Province China

We studied the effects of electroacupuncture at Zusanli （ST 36） on neurons in the colonic myenteric plexus and on defecation in rats with irritable bowel syndrome with constipation （IBS-C）. We also used intragastric administration of pinaverium bromide as a positive control treatment to reveal the pathway mediating the onset of IBS-C. Both electroacupuncture and pinaverium bromide greatly improved defecation in rats with IBS-C. Immunohistochemical staining of the enteric nervous system neuronal marker protein gene product 9.5 in the colonic myenteric plexus showed that electroacupuncture by itself, or in combination with pinaverium bromide, increased the number of neurons and the staining intensity of protein gene product 9.5 in the colonic myenteric plexus. We conclude that visceral hypersensitivity is likely to be a primary cause of constipation in IBS-C rats.

关键词： electroacupuncture irritable bowel syndrome with constipation colonic myenteric plexus neurons pinaverium bromide defecation neural regeneration