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Frontiers of Earth Science 2018年第3期12卷 600-610页

作者： Yang PU Jihong JIA jicheng cao School of Geographical Sciences Nanjing University of Information Science & Technology Nanjing 210044 China

As part of an investigation of the sources of aliphatic hydrocarbons to the sediments of alpine Lake Ximencuo, leaves of the eight dominant vascular plants were collected and their hydrocarbon contents were analyzed. A series of unsaturated aliphatic hydrocarbons were identified in the plant leaves; in particular, Festuca sp. contain a series of n-alkadienes that have rarely been reported in previous studies. The comparison of n-alkane proxies （ACL27 33, ACLT, Paq, and CPI） and δ13Corg among plant leaves, surface soils, and lake sediments suggests that organic proxies have been altered to varying degrees during the transport and burial process of organic materials. It is believed that microbial reworking and source changes have great impacts on organic proxies in the alpine lake system. In addition, the cluster analysis for plant leaves depending on n-alkane compositions and the ACLT proxy generates similar results. Accordingly, we postulate that the average chain length of plant waxes might be a potential indicator of plant classification in regions such as the Qinghai-Tibet Plateau.

关键词： plant leaves alpine lake n-alkanes n-alka-dienes Qinghai-Tibet Plateau (QTP)

An Empirical Application of User-Guided Program Analysis

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China Communications 2024年第7期21卷 325-333页

作者： Wang Jigang Cheng Shengyu cao jicheng He Meihua State Key Laboratory of Mobile Network and Mobile Multimedia Shenzhen 518055China Department of Cyberspace Security ZTE CorporationShenzhen 518057China

Although static program analysis methods are frequently employed to enhance software quality,their efficiency in commercial settings is limited by their high false positive *** EUGENE tool can effectively lower the false positive ***,in continuous integration(CI)environments,the code is always changing,and user feedback from one version of the software cannot be applied to a subsequent ***,people find it difficult to distinguish between true positives and false positives in the analytical *** this study,we developed the EUGENE-CI technique to address the CI problem and the EUGENE-rank lightweight heuristic algorithm to rate the reports of the analysis output in accordance with the likelihood that they are true *** the three projects ethereum,go-cloud,and kubernetes,we assessed our *** to the trial findings,EUGENE-CI may drastically reduce false positives while EUGENE-rank can make it much easier for users to identify the real positives among a vast number of *** paired our techniques with GoInsight~1 and discovered a *** also offered a patch to the community.

关键词： continuous integration report ranking static program analysis

Pharmacokinetics and safety of Morinidazole in patients with impaired hepaticfunction compared with healthy volunteers

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Pharmacokinetics and safety of Morinidazole in patients with...

Effects of different magnetic flux densities on microstructure and magnetic properties of molecular-beam-vapor-deposited nanocrystalline Fee4Ni36 thin films

第十三次全国临床药理学学术大会

作者： Xiaojie Wu,Zhao chen,Jufang Wu,Guoying cao,jicheng Yu,Yaoguo Shi,Yingyuan Zhang,Jing Zhang~* Institute of Antibiotics,Huashan Hospital,Fudan University,Shanghai 200040 Key Laboratory of Clinical Pharmacology of Antibiotics,Ministry of Health,Shanghai 200040

Background A *** study was performed to assess whether hepatic impairment has an effect on the pharmacokinetics of morinidazole and its metabolite *** In a parallel controlled study,a single dose of morinidazole was administered by intravenous infusion to the patients with moderate hepatic impairment(Child-Pugh class B)(n=12)and health controls(n=12)matched for age,gender,weight and height. Blood and urine samples for morinidazole and its N-oxidative metabolite M2 assay were collected predose and at frequent intervals up to 48 hours *** There was no statistical significance in age,gender,weight,

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Frontiers of Materials Science 2015年第2期9卷 163-169页

作者： Yongze cao Qiang WANG Guojian LI Yonghui MA Jiaojiao DU jicheng HE Key Laboratory of Electromagnetic Processing of Materials (Ministry of Education) Northeastern University Shenyang 110819 China

The nanocrystalline Fe64Ni36 thin films were prepared by molecular-beam- vapor deposition under different magnetic flux densities. The microstructure and magnetic properties of thin films were examined by AFM, TEM, HRTEM and VSM. The results show that with the increase of magnetic flux densities, the changing trend of the average particle size is the same as the coercive force except 6 T. Under 6 T condition, the thin film became the mixture of bcc and fcc phases, which leads to slight increase of the coercive force. In addition, the HRTEM result shows the short-range ordered clusters （embryos） or nucleation rate of thin films increase with increasing magnetic flux densities.

关键词： magnetic field intensity microstructure soft magnetic property coerciveforce crystallinity

Renal tubule-targeted dexrazoxane suppresses ferroptosis in acute kidney injury by inhibiting ACMSD

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Nano Research 2023年第7期16卷 9701-9714页

作者： Yunjing Zhang jicheng Wu Quanlin An Huanhuan Zhu Xinwan Su Ying Wang Xishao Xie Jian Zhang Xi Yao Chunhua Weng Shi Feng Jianhua Mao Xianghui Fu Fei Han Xin cao Ben Wang Weiqiang Lin International Institute of Medicine The Fourth Affiliated HospitalZhejiang University School of MedicineJinhua 322000China Institute of Translational Medicine Zhejiang UniversityHangzhou 310029China Cancer Institute(Key Laboratory of Cancer Prevention and Intervention China National Ministry of Education)The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Zhongshan Hospital Institute of Clinical Science Fudan UniversityShanghai 200032China Kidney Disease Center the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Key Laboratory of Kidney Disease Prevention and Control Technology Zhejiang ProvinceHangzhou 310003China Department of Nephrology The Children's HospitalZhejiang University School of Medicine and National Clinical Research Center for Child HealthHangzhou 310000China Division of Endocrinology and Metabolism National Clinical Research Center for GeriatricsState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610041China

Acute kidney injury(AKI)is a heterogeneous clinical complication with no existing definite or particular ***,molecular mechanisms and approaches for treating acute kidney injury are in urgent ***,we demonstrated that dexrazoxane(DXZ),a *** and Drug Administration(FDA)-approved cardioprotective drug,can both functionally and histologically attenuate cisplatin or ischemia-reperfusion injury-induced AKI in vitro and in vivo via inhibiting ferroptosis *** effect is characterized by decreasing lipid peroxidation,shown by the biomarker of oxidative stress 4-hydroxynonenal(HNE)and prostaglandinendoperoxide synthase 2(Ptgs2),while reversing the downregulation of glutathione peroxidase 4(GPX4)and ferritin 1(FTH-1).Mechanistically,the results revealed that DXZ targeted at the renal tubule significantly inhibits ferroptosis by suppressingα-amino-β-carboxymuconate-ε-semialdehyde decarboxylase(ACMSD).Furthermore,the conjugation of dexrazoxane and polysialic acid(DXZ-PSA)is specifically designed and utilized to enhance the therapeutic effect of DXZ by long-term effect in the kidney,especially retention and targeting in the renal *** study provides a novel therapeutic approach and mechanistic insight for AKI by inhibiting ferroptosis through a new type drug DXZPSA with the enhanced renal distribution.

关键词： dexrazoxane dexrazoxane-polysialic acid acute kidney injury ischemia-reperfusion injury ferroptosis α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase(ACMSD)

Teaching Research and Reform of Higher Vocational Medical Education in Guizhou Province of China

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Journal of Advances in Medicine Science 2019年第2期2卷 1-7页

作者： Wan Ding jicheng Lin Jianhui Yang Xianming cao Fang cao Shaomei Lu Qiannan Medical College for Nationalities Duyun Guizhou 558000 China

With the development of Guizhou’s economy and society, higher vocational medical education in Guizhou has developed rapidly, making it its mission to cultivate practical and skilled talents oriented to the grassroots and serving for frontline. However, due to the social environment, policy environment and insufficient funding, many difficulties and problems are faced. It is necessary to have a unified management throughout the province, rationally lay out higher vocational colleges and specialties, and promote the healthy and rapid development of medical higher vocational education in Guizhou with advanced concepts, proper policies, and sufficient funds in place, making higher vocational medical education in Guizhou enter a benign development period.

关键词： Higher vocational medical education in Guizhou Development status Reform Countermeasure research

Health benefits from the rapid reduction in ambient exposure to air pollutants after China's clean air actions:progress in efficacy and geographic equality

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National Science Review 2024年第2期11卷 103-113页

作者： Tao Xue Ruohan Wang Meng Wang Yanying Wang Dan Tong Xia Meng Conghong Huang Siqi Ai Fangzhou Li Jingyuan cao Mingkun Tong Xueqiu Ni Hengyi Liu Jianyu Deng Hong Lu Wei Wan jicheng Gong Shiqiu Zhang Tong Zhu Institute of Reproductive and Child Health National Health Commission Key Laboratory of Reproductive Health/Department of Epidemiology and Biostatistics Ministry of Education Key Laboratory of Epidemiology of Major Diseases(PKU) School of Public Health Peking University Health Science Centre State Environmental Protection Key Laboratory of Atmospheric Exposure and Health Risk Management and Center for Environment and Health Peking University Advanced Institute of Information Technology Peking University Department of Epidemiology and Environmental Health School of Public Health and Health ProfessionsUniversity at Buffalo State Key Joint Laboratory of Environment Simulation and Pollution Control College of Environmental Sciences and EngineeringPeking University Department of Earth System Science Tsinghua University School of Public Health Key Laboratory of Public Health Safety of the Ministry of Education and Key Laboratory of Health Technology Assessment of the Ministry of HealthFudan University College of Land Management Nanjing Agricultural University National&Local Joint Engineering Research Center for Rural Land Resources Use and Consolidation Clean Air Asia

Clean air actions （CAAs） in China have been linked to considerable benefits in public ***,whether the beneficial effects of CAAs are equally distributed geographically is *** high-resolution maps of the distributions of major air pollutants (fine particulate matter[PM2.5]and ozone[O3]) and population,we aimed to track spatiotemporal changes in health impacts from,and geographic inequality embedded in,the reduced exposures to PM2.5and O3from 2013 to *** used a method established by the Global Burden of Diseases *** analyzing the changes in loss of life expectancy（LLE） attributable to PM2.5and O3,we calculated the gain of life expectancy （GLE） to quantify the health benefits of the air-quality ***,we assessed the geographic inequality embedded in the GLE using the Gini index （GI）.Based on risk assessments of PM2.5and O3,during the first stage of CAAs（2013 to 2017）,the mean GLE was 1.87 *** of the sum of the GLE was disproportionally distributed in about one quarter of the population exposed （GI 0.44）.During the second stage of CAAs（2017 to 2020）,the mean GLE increased to 3.94 months and geographic inequality decreased （GI 0.18）.According to our assessments,CAAs were enhanced,from the first to second stages,in terms of not only preventing premature mortality but also ameliorating health *** enhancements were related to increased sensitivity to the health effects of air pollution and synergic control of PM2.5and *** findings will contribute to optimizing future CAAs.

关键词： clean air action public health inequality fine particulate matter ozone

克尔介质中双模纠缠相干光与贝尔态原子相互作用系统的光子统计特性

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光学学报 2007年第4期27卷 727-734页

作者：林继成曹卓良何龙庆南京晓庄学院物理系南京210017 安庆师范学院物理与电气工程学院安庆246011

运用全量子理论并结合数值计算方法,研究了克尔介质腔中处于贝尔态的两个全同二能级纠缠原子与双模纠缠相干光场相互作用系统的光子统计特性。讨论了双原子体系的初态、初始光场的平均光子数、双模纠缠相干光场的纠缠程度以及克尔介质... 详细信息

运用全量子理论并结合数值计算方法,研究了克尔介质腔中处于贝尔态的两个全同二能级纠缠原子与双模纠缠相干光场相互作用系统的光子统计特性。讨论了双原子体系的初态、初始光场的平均光子数、双模纠缠相干光场的纠缠程度以及克尔介质与双模光场的耦合强度对光子统计特性的影响。结果表明:忽略克尔介质的作用时,只有当双原子体系的初态为0β1〉或1β1〉时,在一定的条件下才可出现光子的反聚束效应,而当双原子体系的初态为β00〉、1β0〉时,光场在其演化过程中不出现光子的反聚束效应。而当考虑克尔介质的作用时,四种初态下光场演化过程中均有可能出现光子的反聚束效应。光子的反聚束效应出现的次数、时间和深度极其敏感地依赖于初始光场的平均光子数和克尔介质与双模光场的耦合强度,同时也受到双模纠缠光场的纠缠程度的影响。

关键词：量子光学光子统计克尔介质贝尔态双模纠缠相干光场

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梳棉机刺辊速度对刺辊落棉质量的影响

棉纺织技术 2017年第5期45卷 35-38页

作者：于吉成曹继鹏于学智辽东学院辽宁丹东118003

研究了刺辊速度变化对刺辊落棉质量的影响问题。在不同的刺辊速度条件下,运用USTER AFIS单纤维测试仪对梳棉机的刺辊落棉和盖板花的各项指标进行了检测对比。结果显示,刺辊速度为800r/min时,刺辊落棉中排除短绒和杂质最多;刺辊速度为1 0... 详细信息

研究了刺辊速度变化对刺辊落棉质量的影响问题。在不同的刺辊速度条件下,运用USTER AFIS单纤维测试仪对梳棉机的刺辊落棉和盖板花的各项指标进行了检测对比。结果显示,刺辊速度为800r/min时,刺辊落棉中排除短绒和杂质最多;刺辊速度为1 000r/min时,刺辊落棉中排除的棉结和带籽屑棉结最多;刺辊速度为1 200r/min时,刺辊落棉中排除未成熟纤维最多。认为:合理选择刺辊速度有利于提高梳棉除杂效率和节约用棉。

关键词：刺辊速度刺辊落棉落棉率棉结杂质未成熟纤维

凹面光栅衍射效率测量值的影响因素及补偿方法研究

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光谱学与光谱分析 2013年第11期33卷 3162-3166页

作者：曹海霞巴音贺希格崔继承潘明忠陈少杰中国科学院长春光学机密机械与物理研究所吉林长春130033 中国科学院大学北京100049

通过仪器获得的凹面光栅的衍射效率是相对值,其测量值的精度受测量过程和补偿方法的影响。为使效率测量值的测量精度得到进一步提高,有必要对测量值产生影响的主要因素进行深入研究。该文进一步考察了影响衍射效率测量精度的主要因素,... 详细信息

通过仪器获得的凹面光栅的衍射效率是相对值,其测量值的精度受测量过程和补偿方法的影响。为使效率测量值的测量精度得到进一步提高,有必要对测量值产生影响的主要因素进行深入研究。该文进一步考察了影响衍射效率测量精度的主要因素,针对待测凹面光栅根据待测波长的测试要求进行旋转造成光束截面变化而产生的问题,适当补充原理性方案,并在此基础上推导出了适用于凹面光栅的光束截面变化因子k(θ)的解析表达式。基于影响测量精度因素与理论值之间的非线性关系,提出采用二次非线性回归分析的方法对测量结果进行补偿,给出了提高衍射效率测量精度的补偿公式。实验结果表明,对光栅衍射效率的测量值进行进一步补偿后,使得补偿值与理论值之间的整体误差范围由±2.5%缩小为±0.3%以内,与线性回归分析方法相比,显著缩小了补偿值与理论值之间的差距,进一步保证了衍射效率的准确测量。将补偿过程嵌入测量程序,该方法能够实时补偿测量结果,满足仪器准确测量的要求。

关键词：凹面光栅衍射效率二次非线性回归分析