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绝经后骨质疏松症早期筛查及干预研究进展

中华健康管理学杂志 2024年第2期18卷 146-150页

作者：张亚兰周杰程真师嘉阳陈宗涛陆军军医大学第一附属医院健康管理科重庆400038

绝经后骨质疏松症是绝经后女性发生的以低骨量和骨组织微结构退行性病变为特征的一种全身性骨骼疾病,可导致女性发生骨折、减少寿命。绝经后骨质疏松症临床表现特异性较差,多数患者直到发生疼痛、轻微骨折症状时才被引起重视。因此,早... 详细信息

绝经后骨质疏松症是绝经后女性发生的以低骨量和骨组织微结构退行性病变为特征的一种全身性骨骼疾病,可导致女性发生骨折、减少寿命。绝经后骨质疏松症临床表现特异性较差,多数患者直到发生疼痛、轻微骨折症状时才被引起重视。因此,早期筛查和干预对于绝经后骨质疏松症防治至关重要。近年来,国内外学者研究发现,定量超声检查、骨质疏松症健康风险评估、骨转换标志物检测、生活方式和药物干预等对于骨质疏松症的预测预防有重要作用。本文对相关文献进行综述,以期为绝经后骨质疏松症的早期防治提供思路。

关键词：绝经后骨质疏松症早期筛查早期干预

基于弗兰德斯互动分析法在《健康管理》课程说课比赛中师生语言互动行为效果研究

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中华医学教育探索杂志 2024年第4期23卷 460-464页

作者：师嘉阳陈宗涛陆军军医大学第一附属医院健康管理中心重庆400038

目的采用弗兰德斯互动分析法,研究在健康管理课程说课比赛中师生语言互动行为对教学质量的影响。方法通过对健康管理课程说课比赛中3名参赛教师用弗兰德斯互动分析法模型进行统计收集和分析比赛中师生互动数据,探讨3名教师在课堂互动中... 详细信息

目的采用弗兰德斯互动分析法,研究在健康管理课程说课比赛中师生语言互动行为对教学质量的影响。方法通过对健康管理课程说课比赛中3名参赛教师用弗兰德斯互动分析法模型进行统计收集和分析比赛中师生互动数据,探讨3名教师在课堂互动中的行为、学生的反应以及互动模式的特点。结果说课比赛中发现FIAS矩阵图中,区域E为积极整合格,3名参赛教师的积极整合格与缺陷格频次比远远大于1,3名老师的教学方式都能够缓解课堂紧张气氛,增强师生之间的互动,提高学生的学习效果。C教师与S教师的言语行为分别为91.87%和81.48%,均大于常模;Y教师为52.63%,小于常模,整合教学方式更优于CBL和PBL教学,能更好地帮助学生掌握健康知识和技能,培养健康的生活方式,促进身心健康,并提高健康素养。结论通过使用弗兰德斯互动分析法,教师可以观察和分析与学生之间的互动,评估教学效果,并针对性地提供反馈和改进建议,以提高教学质量和学生学习效果。同时,教师和学生也可以通过观察和分析互动方式,了解自己的优势和不足,并进行相应的授课方式及内容改进,以鼓励学生积极参与课堂互动,提高学习效果和学生满意度。

关键词：弗兰德斯互动分析法健康管理课程说课比赛教师课堂师生语言互动行为

体检人群的健康体适能与代谢性疾病相关指标的相关性研究分析

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健康体检与管理 2024年第3期5卷 218-223,295,M0002页

作者：师嘉阳张亚兰陈宗涛陆军军医大学第一附属医院健康管理中心重庆400038

目的:本研究旨在深入探究体检人群中健康体适能测评指标与代谢性疾病相关指标间的相互关联,为构建体医融合的疾病预防策略及制定个性化的运动干预方案提供科学依据。方法:于2018年1月至2023年12月,以西南地区某体检中心体检人群为研究对... 详细信息

目的:本研究旨在深入探究体检人群中健康体适能测评指标与代谢性疾病相关指标间的相互关联,为构建体医融合的疾病预防策略及制定个性化的运动干预方案提供科学依据。方法:于2018年1月至2023年12月,以西南地区某体检中心体检人群为研究对象,测试肌肉含量、体脂率、握力、坐位体前屈和肺活量等健康体适能指标,采血检测空腹血糖(FPG),血脂指标甘油三酯(TG)、血清总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)等,以及尿酸等代谢性疾病指标,分析体适能测评指标与血糖、血脂和尿酸的关系。结果:坐位体前屈、平衡能力与尿酸、TG和FPG呈负相关(P<0.05),与HDL-C呈正相关(P<0.05);选择反应时与FPG和TC呈负相关(P<0.05),与尿酸呈正相关(P<0.05);握力、心肺耐力与HDL-C呈正相关(P<0.05),与尿酸、TG和FPG水平呈负相关(P<0.05)。结论:体适能测评指标与血脂、血糖和尿酸密切相关,可用于预测人群的健康状况。

关键词：空腹血糖血脂异常体检人群健康体适能尿酸

The risk factors and threshold level of subchronic inhalation exposure of reclaimed water

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Journal of Environmental Sciences 2024年第3期137卷 639-650页

作者： jiayang Kong Yun Lu Yunru Ren Menghao Chen Gang Liu Liangliang shi State Key Joint Laboratory of Environment Simulation and Pollution Control State Environment Protection Key Laboratory of Microorganism Application and Risk ControlSchool of EnvironmentTsinghua UniversityBeijing 100084China

Inhalation of reclaimed water is known to cause lung infammation,and free endotoxins have been shown to be a major risk factor for acute *** exposure has also been shown to induce infammatory responses with visible tissue ***,subchronic risk factors have yet to be identified,and a threshold for the protection of occupational populations during urban reuse is *** this study,potential risk factors in reclaimed water were examined by subchronic exposure with fractionated reclaimed water,and the health risk threshold was tested with a series of diluted reclaimed ***,following a 12-week exposure,macromolecules and microorganisms were found to be two major risk factors in reclaimed water that could cause pulmonary infammation,including increased proportion of polymorphonuclear leukocytes in bronchoalveolar fuid,formation of inducible bronchus-associated lymphoid tissue,and elevation of Immunoglobulin A ***,infammation persisted after a 4-week recovery *** calculated threshold of reclaimed water exposure for mice was 31.8 Endotoxin Unit(EU)/(kg·day)under when exposed to 50%additional relative humidity from reclaimed water at 25℃ for 2 hr/***,the subchronic threshold estimate for humans under the same exposure conditions was found to be 12.2 EU/(kg·day),corresponding to endotoxin levels of 61.7 EU/mL in reclaimed *** threshold level of endotoxin was lower than that in most non-potable reclaimed *** findings of this study suggest that occupational exposure of reclaimed water can serve as a potential risk to workers.

关键词： Reclaimed water Inhalation exposure Risk factor Threshold Infammation Endotoxin

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ABO血型的糖尿病发病风险研究

重庆医学 2024年第9期53卷 1360-1364页

作者：张亚兰王新孙丽师嘉阳程真陈宗涛陆军军医大学第一附属医院健康管理科重庆400038 四川大学华西公共卫生学院成都610041

目的探讨ABO血型的糖尿病发病风险。方法回顾性分析2006—2018年陆军军医大学第一附属医院健康管理科的1306397例健康体检者资料,包括性别、年龄、身高、体重、血糖、血脂和ABO血型等,将其中同时有血型和空腹血糖数据的61296例体检者作... 详细信息

目的探讨ABO血型的糖尿病发病风险。方法回顾性分析2006—2018年陆军军医大学第一附属医院健康管理科的1306397例健康体检者资料,包括性别、年龄、身高、体重、血糖、血脂和ABO血型等,将其中同时有血型和空腹血糖数据的61296例体检者作为研究人群,采用多因素logistic回归分析不同ABO血型的糖尿病发病风险。结果总人群和研究人群中性别、年龄、BMI分布比较,差异有统计学意义(P<0.05)。研究人群中糖尿病、糖尿病前期人数分别为2649例(4.3%)和3979例(6.5%)。不同血型人群的胆固醇、低密度脂蛋白-胆固醇(LDL-C)、糖尿病、糖尿病前期人群分布比较,差异有统计学意义(P<0.05)。多因素logistic回归分析结果显示,与O型血相比,A型血糖尿病发病风险增加(OR=1.38,95%CI:1.02~1.86,P=0.04),而B型血(OR=1.28,95%CI:0.93~1.77,P=0.13)和AB型血(OR=1.33,95%CI:0.83~2.11,P=0.23)不会增加糖尿病的发病风险。结论可对A型血人群进行早期筛查并采取预防性治疗和干预以降低糖尿病的发病率。

关键词：糖尿病糖代谢异常 ABO血型发病风险高危人群

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Control of Bird Feeding Behavior by Tannin1 through Modulating the Biosynthesis of Polyphenols and Fatty Acid-Derived Volatiles in Sorghum

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Molecular Plant 2019年第10期12卷 1315-1324页

作者： Peng Xie jiayang shi Sanyuan Tang Chengxuan Chen Aimal Khan Fengxia Zhang Ying Xiong Chao Li Wei He Guodong Wang Fumin Lei Yaorong Wu Qi Xie State Key Laboratory of Plant Genomics Institute of Genetics and Developmental BiologyThe Innovative Academy of Seed DesignChinese Academy of SciencesBeijing 100101P.R.China University of Chinese Academy of Sciences Beijing 100049P.R.China Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101P.R.China School of Pharmaceutical Sciences Tsinghua UniversityBeijing 100084P.R.China

Bird predation during seed maturation causes great loss to agricultural *** this study,through GWAS analysis of a large-scale sorghum germplasm diversity panel,we identified that Tannin1,which encodes a WD40 protein functioning in the WD40/MYB/bHLH complex,controls bird feeding behavior in *** profiling analysis showed that a group of sorghum accessions preferred by birds contain mutated tan1-a/b alleles and accumulate significantly lower levels of anthocyanins and condensed tannin *** contrast,a variety of aromatic and fatty acid-derived volatiles accumulate at significantly higher levels in these bird-preference *** subsequently conducted both sparrow feeding and sparrow volatile attractant assays,which confirmed,respectively,the antifeedant and attractant functions of these differentially accumulated *** addition,the connection between the biosynthesis pathway of anthocyanin and proanthocyanidin and the pathway of fatty acid–derived volatile biosynthesis was demonstrated by discovering that Tannin1 complex modulates fatty acid biosynthesis by regulating the expression of SbGL2 in sorghum,thus affecting the accumulation of fatty acid-derived *** together,our study identified Tannin1 as the gene underlying the major locus controlling bird feeding behavior in sorghum,illustrating an example of the identification of an ecologically impactful molecular mechanism from field observation and providing significant insights into the chemistry of bird–plant ecological interactions.

关键词： bird damage GWAS metabolism tannin volatiles

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SVG在风力发电系统中的应用

电力大数据 2018年第5期21卷 47-51页

作者：史家洋粤电集团贵州有限公司贵州贵阳550081

风电技术的巨大进步,使得风电的开放和利用占据了新能源的主导地位,但由于风资源的不确定性和风电机组本身的运行特性使风电机组的输出功率是波动的,导致产生出线并网功率因数不合格、电压偏差、电压波动和闪变等问题,给配电系统的电压... 详细信息

风电技术的巨大进步,使得风电的开放和利用占据了新能源的主导地位,但由于风资源的不确定性和风电机组本身的运行特性使风电机组的输出功率是波动的,导致产生出线并网功率因数不合格、电压偏差、电压波动和闪变等问题,给配电系统的电压无功带来了很大的影响。考虑双馈风力发电机自身的无功输出特点,对于大容量风电场接入系统时还存在稳定性问题;同时系统电压的波动也会对风机的正常运行造成影响。上述问题都可以通过合理的配置无功补偿得到改善。本文以解决风电场合理配置无功补偿为目的,详细介绍了SVG的基本原理、控制方法、优缺点,研究了SVG在其电压无功控制时的应用,通过电流直接控制和电流间接控制两种方法,详细探讨了SVG并网时的关键技术点,同时结合具体工程实践介绍了SVG在风电场升压站的工程注意事项以及应用SVG之后电网电能质量的改善情况。实现了电网电压稳定性的要求,改善电压质量,提高供电设备的功率因数,减少输电线路无功消耗。

关键词： SVG 风力发电无功补偿电能质量

D53 represses rice blast resistance by directly targeting phenylalanine ammonia lyases

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Journal of Integrative Plant Biology 2024年第9期66卷 1827-1830页

作者： Haitao Ye Qingqing Hou Haitao Lv Hui shi Duo Wang Yujie Chen Tangshuai Xu Mei Wang Min He Junjie Yin Xiang Lu Yongyan Tang Xiaobo Zhu Lijuan Zou Xuewei Chen jiayang Li Bing Wang Jing Wang State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130China Key Laboratory of Seed Innovation Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China Yazhouwan National Laboratory Sanya 572024China

Phytohormones play important roles in orchestrating plantimmune responses to pathogen ***(SLs),a group of carotenoid-derived phytohormones,modulate diverse biological processes in plants,including shoot branching,plant height,root architecture,leaf senescence,seed germination of parasitic plants,and symbiosis of arbuscular mycorrhizal fungi(Burger and Chory,2020).Recently,increasing evidence has indicated potential roles for SLs in regulating responses against biotic stresses,including defense responses against certain pathogenic fungi and bacteria in roots and leaves(Yi et al.,2023).

关键词： ammonia resistance branching

Adaptive Space Expansion for Fast Motion Planning

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1499-1514页

作者： Shenglei shi Jiankui Chen State Key Laboratory of Digital Manufacturing Equipment and Technology School of Mechanical Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

The sampling process is very inefficient for sam-pling-based motion planning algorithms that excess random sam-ples are generated in the planning *** this paper,we pro-pose an adaptive space expansion(ASE)approach which belongs to the informed sampling category to improve the sampling effi-ciency for quickly finding a feasible *** ASE method enlarges the search space gradually and restrains the sampling process in a sequence of small hyper-ellipsoid ring subsets to avoid exploring the unnecessary ***,for a con-structed small hyper-ellipsoid ring subset,if the algorithm cannot find a feasible path in it,then the subset is ***,the ASE method successively does space exploring and space expan-sion until the final path has been ***,we present a particular construction method of the hyper-ellipsoid ring that uniform random samples can be directly generated in *** last,we present a feasible motion planner BiASE and an asymptoti-cally optimal motion planner BiASE*using the bidirectional exploring method and the ASE *** demon-strate that the computation speed is much faster than that of the state-of-the-art *** source codes are available at https://***/shshlei/ompl.

关键词： Adaptive space expansion(ASE) hyper-ellipsoid ring informed sampling motion planning.