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Nano Research 2023年第8期16卷 10803-10809页

作者： Yumei Liu Tiantian wu Hongfei Cheng jiawen wu Xiaodong Guo Hong Jin Fan College of Chemical Engineering Sichuan UniversityChengdu 610065China School of Physical and Mathematical Sciences Nanyang Technological UniversitySingapore 637371Singapore School of Chemistry Xi’an Key Laboratory of Sustainable Energy Materials ChemistryState Key Laboratory of Electrical Insulation and Power EquipmentXi’an Jiaotong UniversityXi’an 710049China Institute of Materials Research and Engineering A*STAR2 Fusionopolis WaySingapore 138634Singapore

Formic acid is considered one of the most economically viable products for electrocatalytic CO_(2)reduction reaction(CO_(2)RR).However,developing highly active and selective electrocatalysts for effective CO_(2)conversion remains a grand challenge.Herein,we report that structural modulation of the bismuth oxide nanosheet via Zn^(2+)cooperation has a profound positive effect on exposure of the active plane,thereby contributing to high electrocatalytic CO_(2)RR performance.The obtained Zn-Bi_(2)O_(3)catalyst demonstrates superior selectivity towards formate generation in a wide potential range;a high Faradaic efficiency of 95%and a desirable partial current density of around 20 mA·cm^(-2)are obtained at−0.9 V(vs.reversible hydrogen electrode(RHE)).As proposed by density functional theory calculations,Zn substitution is the most energetically feasible for forming and stabilizing the key OCHO*intermediate among the used metal ions.Moreover,the more negative adsorption energy of OCHO*and the relatively low energy barrier for the desorption of HCOOH*are responsible for the enhanced activity and selectivity.

关键词： electrocatalytic CO_(2)reduction Bi_(2)O_(3)catalyst active plane modulation Zn substitution high selectivity

Bilirubin inhibits lung carcinogenesis by up-regulating cystatin A expression in tumor-infiltrating macrophages

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Genes & Diseases 2023年第6期10卷 2222-2225页

作者： Qingtian Huang Na Zhang Jiangtuan Wang Hua Xu Leyi Yao Qianqian Yang Ding Yan Xi Chen Qian Xue Min Xiao jiawen wu Xueheng wu Qin Liu Daolin Tang Xin Chen Xiaofen Li Jinbao Liu Affiliated Cancer Hospital&Institute of Guangzhou Medical University GuangzhouGuangdong 510095China Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation School of Basic Medical SciencesGuangzhou Medical UniversityGuangzhouGuangdong 511436China Institute of Digestive Disease The Sixth Affiliated Hospital of Guangzhou Medical UniversityQingyuan People's HospitalQingyuanGuangdong 511518China Department of Pathology Dongguan People's Hospital Affiliated to Southern Medical UniversityDongguanGuangdong 523059China Department of Surgery UT Southwestern Medical CenterDallasTX 75390USA

As one of the leading causes of cancer deaths worldwide,the pathogenesis of lung cancer is still not completely understood.Bilirubin,a product of heme metabolism,has long been considered a waste product of the body.Increasing evidence suggests that bilirubin has additional antioxidant,anti-inflammatory,and proteasome inhibitory activities.However,the specific role of bilirubin in the formation and development of lung cancer has not been elucidated.

关键词： lung metabolism cancer

Evaluation of the performance of alternative assessment configurations to account for the spatial heterogeneity in age-structure: a simulation study based on Indian Ocean albacore tuna

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Acta Oceanologica Sinica 2019年第10期38卷 9-19页

作者： Wenjiang Guan jiawen wu Siquan Tian College of Marine Sciences Shanghai Ocean UniversityShanghai 201306China Key Laboratory of Sustainable Exploitation of Oceanic Fisheries Resources Ministry of EducationShanghai 201306China

Various population structures or spatial heterogeneities in population distribution have been an important source of model misspecification and have had an impact on estimation performance in fisheries stock assessment.In this study,we simulated the Indian Ocean albacore spatial heterogeneity in age-structure using Stock Synthesis according to the stage-dependent migration rate and region-dependent fishing mortality rate and generated the stock assessment data.Based on these data,we investigated the performances of different spatial configurations,selectivity curves and selections of CPUE(catch per unit effort)indices of the assessment models which were used to account for spatial heterogeneity.The results showed:(1)although the spatially explicit configurations,which exactly matched the operating model,provided unbiased and accurate estimates of relative spawning biomass,relative fishing mortality rate and maximum sustainable yield in all simulation scenarios,their performance may be very poor if there were mismatches between them and the operating model due to gaps in knowledge and data;(2)for spatially explicit assessment configuration,the correct boundary was required,but for non-spatially explicit assessment configuration,it seemed more important for analysts to partition the area to properly reflect the transition in field data and to effectively account for the impacts of ignoring the spatial structure by using the additional spatially referenced parameters;(3)although the areas-as-fleets methods and flexible time-varying selectivity curves could be used as better alternative approaches to account for spatial structure,these configurations could not completely eliminate the impacts of model misspecification and the quality of estimates of different quantities from the same assessment model may be inconsistent or the performance of the same assessment configuration may fluctuate significantly between simulation scenarios;(4)although the worst estimates could generally be avoided by using multiple CPUE indic

关键词： spatial structure simulation stock assessment Indian Ocean Thunnus alalunga

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乡村生态振兴法治保障的困境与出路

肇庆学院学报 2024年第1期45卷 7-12页

作者：侯军亮吴家文广东理工学院马克思主义学院广东肇庆526100

在中国式现代化和乡村振兴战略背景下,推进乡村全面依法治理是时代必然。乡村生态振兴是乡村振兴的重要环节,亦是落实习近平生态文明思想的应有之义。我国推进乡村生态振兴具有深厚的思想渊源与理论基础,但这需要法治的保障。当前在乡... 详细信息

在中国式现代化和乡村振兴战略背景下,推进乡村全面依法治理是时代必然。乡村生态振兴是乡村振兴的重要环节,亦是落实习近平生态文明思想的应有之义。我国推进乡村生态振兴具有深厚的思想渊源与理论基础,但这需要法治的保障。当前在乡村生态环境方面存在生态立法不够完备,执法权责模糊,司法能动不足,监督体系不严等问题。因此,未来需要通过强化法治自觉,落实法治行动,深化法治担当,提升法治理念,来完善乡村生态振兴立法体系,严格乡村生态振兴执法规范,发挥乡村生态振兴司法能动性为乡村生态振兴注入新动能提供法治保障。

关键词：法治思想乡村振兴生态保护法治保障

中国居民预防性储蓄与财富积累研究——基于2010-2016年CFPS数据

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湖北师范大学学报（哲学社会科学版） 2024年第2期44卷 19-30页

作者：杨灿武嘉文湖北师范大学经济管理与法学院湖北黄石435002

利用CFPS2010-2016年数据分析收入不确定性对中国城乡家庭财富积累的影响,结果证实了预防性储蓄动机的存在。为了进一步探究预防性储蓄对家庭财富积累的贡献度,本文从数理模型推导上得出收入不确定性对家庭财富积累的贡献度,并对预防性... 详细信息

利用CFPS2010-2016年数据分析收入不确定性对中国城乡家庭财富积累的影响,结果证实了预防性储蓄动机的存在。为了进一步探究预防性储蓄对家庭财富积累的贡献度,本文从数理模型推导上得出收入不确定性对家庭财富积累的贡献度,并对预防性储蓄的重要性进行量化分析,结果发现预防性储蓄占家庭金融性财产的18%-28%。并从财产水平和生命周期两个视角探究预防性储蓄对家庭财富积累的作用机制。

关键词：预防性储蓄财富积累永久性收入收入不确定性

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中国式现代化话语体系的审思与建构

江苏科技大学学报（社会科学版） 2024年第1期24卷 8-14页

作者：吴佳雯李效东北京交通大学马克思主义学院北京100044

在推进中国式现代化进程中,中国式现代化话语体系的建构是实现现代化强国目标的题中要义,是把握好“两个大局”的必然要求,是发展中国家现代化的重要参照。中国式现代化话语体系建构面临西方话语霸权的窠臼与偏见、话语内容要素的滞后... 详细信息

在推进中国式现代化进程中,中国式现代化话语体系的建构是实现现代化强国目标的题中要义,是把握好“两个大局”的必然要求,是发展中国家现代化的重要参照。中国式现代化话语体系建构面临西方话语霸权的窠臼与偏见、话语内容要素的滞后与区隔和话语表达手段的零散与单一的现实困境。因此必须形塑话语内容,创新话语表达,改善话语环境,聚合话语力量,推动中国式现代化话语体系的建构和完善。

关键词：中国式现代化话语体系话语建构

初中化学“物质分离与提纯”的项目式教学设计——保护滇池母亲湖争做小小水质检测员

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云南化工 2024年第2期51卷 209-215页

作者：刘清清吴琦吴嘉雯李睿云南师范大学化学化工学院云南昆明650500

以滇池水质的检测和净化为项目核心,开展初中化学关于物质分离与提纯的教学。通过“取水、确定检测指标”“探究如何降低滇池水的色度”“探索如何降低滇池水的电导率”等三个子项目来帮助学生构建物质分离和提纯的思维模型。利用手持... 详细信息

以滇池水质的检测和净化为项目核心,开展初中化学关于物质分离与提纯的教学。通过“取水、确定检测指标”“探究如何降低滇池水的色度”“探索如何降低滇池水的电导率”等三个子项目来帮助学生构建物质分离和提纯的思维模型。利用手持技术数字化实验,测定了滇池水质指标,并与蒸馏水进行对比,从定性和定量两个角度来探究滇池水质净化的效果。学生从滇池水质的检测到净化过程中解决了一系列复杂的问题,在此过程中发展了“结构—性质—用途”的重要化学观念、科学思维、科学探究与实践,以及“树立生态文明理念”的科学态度与责任等化学学科核心素养。

关键词：项目式教学滇池水检测与净化物质分离提纯

GPU-BASED FLUID SIMULATION WITH FAST COLLISION DETECTION ON BOUNDARIES

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International Journal of Modeling, Simulation, and Scientific Computing 2012年第1期3卷 137-148页

作者： jiawen wu FENGQUAN ZHANG XUKUN SHEN State Key Laboratory of Virtual Reality Technology and System Beihang University 100191 BeijingChina

In this paper,we present a method for fluid simulation based on smoothed particle hydrodynamic(SPH)with fast collision detection on boundaries on GPU.The major goal of our algorithm is to get a fast SPH simulation and rendering on GPU.Additionally,our algorithm has the following three features:At first,to make the SPH method GPU-friendly,we introduce a spatial hash method for neighbor search.After sorting the particles based on their grid index,neighbor search can be done quickly on GPU.Second,we propose a fast particle-boundary collision detection method.By precomputing the distance field of scene boundaries,collision detection’s computing cost arrived as O(n),which is much faster than the traditional way.Third,we propose a pipeline with fine-detail surface reconstruction,and progressive photon mapping working on GPU.We experiment our algorithm on different situations and particle numbers of scenes,and find out that our method gets good results.Our experimental data shows that we can simulate 100K particles,and up to 1000K particles scene at a rate of approximately 2 times per second.

关键词： SPH simulation fast collision detection GPU progressive photon mapping

超级微波消解-电感耦合等离子体质谱法测定婴幼儿奶粉中钙和磷的含量

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中国乳品工业 2024年第2期52卷 55-58,64页

作者：陈晓敏吴嘉文胡雯艳陈韵郑灿松广州市食品检验所广州511400

建立超级微波消解-电感耦合等离子体质谱法测定婴幼儿奶粉中钙和磷含量的方法。样品采用超级微波消解前处理,利用碰撞反应技术和在线内标法优化检测方法,通过标准物质、加标回收试验和方法比对等手段进行方法学验证。结果表明,钙的线性... 详细信息

建立超级微波消解-电感耦合等离子体质谱法测定婴幼儿奶粉中钙和磷含量的方法。样品采用超级微波消解前处理,利用碰撞反应技术和在线内标法优化检测方法,通过标准物质、加标回收试验和方法比对等手段进行方法学验证。结果表明,钙的线性范围为0~150 mg/L,磷的线性范围为0~100 mg/L,相关系数均大于0.9995,钙和磷的方法检出限分别为0.527 mg/kg和0.232 mg/kg,方法定量限分别为1.75 mg/kg和0.774 mg/kg,相对标准偏差分别为1.17%和0.67%;质控样品钙和磷的测定结果均在特定值区间内,且加标回收率的范围为96.3%~104.4%;并对市售的多个奶粉进行方法比对,结果不存在显著性差异。试验表明该方法能减少基质干扰,能简单、快速、准确、稳定地同时检测婴幼儿奶粉中钙和磷的含量,为今后婴幼儿奶粉中钙和磷含量同时测定提供方法参考。

关键词：电感耦合等离子体质谱法婴幼儿奶粉钙磷超级微波消解

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中医药调控肺癌辐射治疗作用机制研究进展

中国实验方剂学杂志 2024年第8期30卷 253-261页

作者：王玉张露汤磊磊于东东蒋文静吴家文陆婷婷安徽中医药大学中西医结合学院合肥230012 安徽中医药大学第一附属医院合肥230031 安徽中医药大学新安医学教育部重点实验室合肥230031 安徽省中医药科学院中医呼吸病防治研究所合肥230031

肺癌是全球范围内发病率和死亡率增长最快的癌症类型,对于人群生命健康构成巨大威胁。辐射治疗是肺癌治疗的主要方法之一,肺癌的局部控制率与辐射剂量呈明显的剂量-效应学关系,但肺为辐射剂量受限器官,肺癌组织的辐射抵抗和正常组织的... 详细信息

肺癌是全球范围内发病率和死亡率增长最快的癌症类型,对于人群生命健康构成巨大威胁。辐射治疗是肺癌治疗的主要方法之一,肺癌的局部控制率与辐射剂量呈明显的剂量-效应学关系,但肺为辐射剂量受限器官,肺癌组织的辐射抵抗和正常组织的辐射损伤限制了肺癌辐射疗效。肺癌中医病机为正气先虚,邪气内侵,渐积而成。肺癌辐射治疗后,机体正气愈虚,痰凝气滞、瘀血阻络更甚,导致肺癌组织辐射抗性产生并增强。因此,使用药物提升肺癌细胞的辐射敏感性和改善正常肺组织的辐照耐受性是显著提高肺癌患者辐射治疗临床疗效的关键问题。中医药作为辐射增敏剂,通过调节细胞周期增加辐射敏感期细胞比例、促进促凋亡基因上调及抗凋亡基因下调诱导细胞凋亡、增强辐照引起的脱氧核糖核酸(DNA)损伤和抑制损伤修复、改善血液循环及组织供氧等机制提高肿瘤细胞对辐照的敏感性,放大辐射对肿瘤组织的损伤。中医药也可作为辐射防护剂,通过抑制细胞损伤、调节细胞因子和免疫平衡、减少炎症因子和纤维化因子释放及抑制相关信号通路激活等方面发挥防治放射性肺损伤的作用。该文对近年来中医药肺癌辐射增敏及辐射防护相关研究成果进行系统梳理,旨在阐明中医药调控肺癌辐射治疗作用机制,为中医药参与肺癌辐射治疗改善肺癌患者预后提供更多的理论和实践依据。

关键词：中医药肺癌辐射增敏辐射防护放射性肺损伤