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不同剪枝量对桃树生长与结果的影响

中国果树 2024年第2期 32-37页

作者：刘晓飞康玲彭佳伟崔梅鹤杨丽陈海江田义河北农业大学园艺学院保定071000 保定市东风公园河北省山区农业技术创新中心国家北方山区农业工程技术研究中心

修剪是促使桃园能够优质、高产最为关键的管理措施之一。以瑞蟠10号和雨花2号两个桃品种为试材,于休眠期分别进行无修剪(0剪枝量,延迟修剪)、轻剪(约50%剪枝量)和正常剪(约70%剪枝量)等3种剪枝量处理,以便探究休眠期不同剪枝量处理对于... 详细信息

修剪是促使桃园能够优质、高产最为关键的管理措施之一。以瑞蟠10号和雨花2号两个桃品种为试材,于休眠期分别进行无修剪(0剪枝量,延迟修剪)、轻剪(约50%剪枝量)和正常剪(约70%剪枝量)等3种剪枝量处理,以便探究休眠期不同剪枝量处理对于树体生长和结果所造成的影响。结果显示:瑞蟠10号桃延迟修剪、轻剪处理在6月底时的短枝比率分别是正常剪处理的2.00、1.90倍,而雨花2号桃延迟修剪、轻剪处理在6月底时的短枝比率分别是正常剪处理的1.19、1.17倍;瑞蟠10号和雨花2号桃轻剪处理667 m2产量均高于正常剪处理和延迟修剪处理,但可溶性固形物、可滴定酸含量均与正常剪处理无显著差异。研究结果对桃生产中的修剪管理具有一定的指导意义。

关键词：桃剪枝量短枝比率果实品质产量

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LMNA基因突变心肌病子代传递阻断1例

中华心血管病杂志 2024年第5期52卷 538-541页

作者：赵晓燕王丹王楚楚徐家伟杜文婷赵静郭雅丽卢艳雨毛云李小威王晓娟郭艺红李凌董建增郑州大学第一附属医院心血管内科郑州450052 郑州大学生命科学学院生物信息学系郑州450000 郑州大学第一附属医院生殖医学中心郑州450052 郑州大学第一附属医院产科郑州450052

LMNA基因编码的核纤层蛋白A/C是核膜的组成成分。该基因的致病性突变可导致家族性扩张型心肌病,遗传方式为常染色体显性遗传;LMNA突变引起的家族性扩张型心肌病常累及心脏传导系统,表现为多种心律失常,包括窦房结功能障碍、心房颤动、... 详细信息

LMNA基因编码的核纤层蛋白A/C是核膜的组成成分。该基因的致病性突变可导致家族性扩张型心肌病,遗传方式为常染色体显性遗传;LMNA突变引起的家族性扩张型心肌病常累及心脏传导系统,表现为多种心律失常,包括窦房结功能障碍、心房颤动、房室传导阻滞、室性心动过速和心室颤动,最终出现心室扩张和心力衰竭,猝死风险高。该文报道1例家族性扩张型心肌病女性患者,基因检测示LMNA c.1489-1G>C突变,通过应用胚胎植入前遗传学检测筛选出不携带致病基因的囊胚进行胚胎移植,成功妊娠并生育健康后代。

关键词：心肌病 LMNA基因突变致病性变异胚胎植入前遗传学检测子代传递阻断常染色体显性遗传基因测序心律失常

Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cells

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Cellular & Molecular Immunology 2021年第9期18卷 2153-2164页

作者： Muxin Yu Hong Pan Nan Che Li Li Cong Wang Yue Wang Ge Ma Mengjia Qian jiawei Liu Mingjie Zheng Hui Xie Lijun ling Yi Zhao Xiaoxiang Guan Qiang Ding Wenbin Zhou Shui Wang Department of Breast Surgery The First Affiliated Hospital of Nanjing Medical University300 Guangzhou RoadNanjing210029China Jiangsu Key Lab of Cancer Biomarkers Prevention and TreatmentJiangsu Collaborative Innovation Center For Cancer Personalized MedicineSchool of Public HealthNanjing Medical UniversityNanjing211166China Department of Rheumatology and Immunology The First Affiliated Hospital of Nanjing Medical University300 Guangzhou RoadNanjing210029China Department of General Surgery Huashan HospitalFudan UniversityShanghai200040China Department of Pathology The First Affiliated Hospital of Nanjing Medical University300 Guangzhou RoadNanjing210029China Department of Oncology The First Affiliated Hospital of Nanjing Medical University300 Guangzhou RoadNanjing210029China

Surgery is essential for controlling the symptoms and complications of stage IV breast ***,locoregional treatment of primary tumors often results in distant progression,including lung metastasis,the most common type of visceral *** a minimally invasive thermal therapy,microwave ablation(MWA)has been attempted in the treatment of breast cancer,but the innate immune response after MWA has not yet been *** two murine models of stage IV breast cancer,we found that MWA of primary breast cancer inhibited the progression of lung metastasis and improved *** cells were activated after MWA of the primary tumor and exhibited enhanced cytotoxic functions,and the cytotoxic pathways of NK cells were *** experiments showed that NK cells but not CD4+or CD8+T cells played a pivotal role in prolonging ***,we found that compared with surgery or control treatment,MWA of the primary tumor induced completely different NK-cell-related cytokine *** were activated after MWA of the primary tumor and produced IL-15 that activated NK cells to inhibit the progression of *** addition,MWA of human breast cancer stimulated an autologous NK-cell *** results demonstrate that MWA of the primary tumor in metastatic breast cancer inhibits metastatic progression via the macrophage/IL-15/NK-cell *** of the primary tumor may be a promising treatment strategy for de novo stage IV breast cancer,although further substantiation is essential for clinical testing.

关键词： breast cancer microwave ablation metastasis NK cells surgery

Niobium carbide(MXene)reduces UHMWPE particle-induced osteolysis

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Bioactive Materials 2022年第2期7卷 435-448页

作者： Kuo-Yang Sun Yizhang Wu Jia Xu Wenfang Xiong Wei Xu jiawei Li Ziying Sun Zhongyang Lv XSWu Qing Jiang Hong-ling Cai Dongquan Shi State Key Laboratory of Pharmaceutical Biotechnology Department of Sports Medicine and Adult Reconstructive SurgeryNanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical School321 Zhongshan RoadNanjing210008JiangsuPR China Collaborative Innovation Center of Advanced Microstructures Laboratory of Solid State Microstructures and School of PhysicsNanjing UniversityNanjing210093China Drum Tower of Clinical Medicine Nanjing Medical UniversityNanjing210008JiangsuPR China Department of Gastroenterology Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical School321 Zhongshan RoadNanjing210008JiangsuPR China

Joint replacement surgery is one of the orthopedic surgeries with high successful rates;however,wear debris generated from prostheses can ultimately lead to periprosthetic osteolysis and failure of the *** implant-derived particulate debris such as ultrahigh molecular weight polyethylene(UHMWPE)can initiate the local immune response and recruit monocytic cells to phagocytose particles for generating reactive oxygen species(ROS).ROS induces osteoclastogenesis and macrophages to secrete cytokines which ultimately promote the development of *** this work,we develop the few-layered Nb_(2)C(FNC)as an antioxidant which possesses the feature of decreasing the production of cytokines and inhibiting osteoclastogenesis by its ROS ***,local injection of FNC attenuates the UHMWPE-induced osteolysis in a mouse calvarial *** sum,our results suggest that FNC can be used for treating osteolytic bone disease caused by excessive osteoclastogenesis.

关键词： Periprosthetic osteolysis MXene Niobium carbide Osteoclastogenesis Reactive oxygen species(ROS)

The effect of aerobic dancing on physical fitness and cognitive function in older adults during the COVID-19 pandemic-a natural experiment

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Sports Medicine and Health Science 2023年第3期5卷 196-204页

作者： Lin Wang Fei Guo Chenxi Zhao Minmin Zhao Chenglei Zhao jiawei Guo Longhai Zhang ling Zhang Zheng'ao Li Wenfei Zhu School of Physical Education Shaanxi Normal University710100Xi'anShaanxi ProvinceChina

During the Coronavirus disease(COVID-19),the physical activity of older adults is at a lower *** study aimed to examine the effectiveness of aerobic dancing on physical fitness and cognitive function in older *** conducted a randomized controlled trial with 34 older adults who were assigned into an aerobic dancing group and a control *** dance sessions weekly for 60min were scheduled for the aerobic dancing group for a total of 12 *** fitness,blood pressure,lipids,glucose,cognitive function were assessed before and after the *** adjusted Analysis of Covariance(ANCOVA)was used to determine whether outcome variables varied between groups at pre-test and *** size(Cohen's d)was calculated to determine the differences between groups from baseline to *** 12 weeks,we found that the aerobic dancing group showed significant improvement in memory(portrait memory:F=10.45,p=0.003,d=1.18).The Limit of Stability(LOS)parameters in the aerobic dancing group displayed a significant increase after the intervention(right angle:F=5.90,p=0.022,d=0.60;right-anterior angle:F=4.23,p=0.049,d=0.12).Some beneﬁcial effects were found on flexibility,grip strength,balance and subjective well-being(sit and reach:F=0.25,p=0.62,d=−0.40;grip strength:F=3.38,p=0.08,d=0.89;one-legged standing with eyes closed:F=1.26,p=0.27,d=0.50)in the aerobic dancing *** dancing training was effective in improving memory and balance ability in older adults during the COVID-19 pandemic in *** the future,aerobic dancing is a promising tool to encourage physical activity in older adults.

关键词： Aerobic dancing Older adults Physical fitness Cognitive function Balance

Changes in the Chinese Population's Fertility Intentions:1980-2011

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Social Sciences in China 2015年第1期36卷 46-63页

作者：侯佳伟 Huang Silin Xin Ziqiang Sun ling Zhang Hongchuan Dou Donghui Zhao Yuanyuan School of Social Development Central University of Finance and Economics

On the basis of the findings of 227 surveys of Chinese fertility intentions over the years 1980-2011, this paper investigates the longitudinal changes in fertility intentions through cross-temporal meta-analysis. It is found that the ideal number of children for the Chinese trended downwards from 1980, but since 2000 the average number has remained basically stable at 1.6 to 1.8. In the 1980s, people＇s fertility levels were higher than their fertility intentions. With economic and educational progress in China, both fertility levels and fertility intentions showed a downward trend, with the former declining faster than the latter. Since 1990, people＇s fertility levels have been lower than their fertility intentions; that is, their actual number of children has been less than their ideal number. This provides an empirical basis for examining the changes in China＇s fertility intentions and fertility levels.

关键词： fertility intentions ideal number of children gender preference fertility level cross-temporal recta-analysis

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子宫内膜癌合并多原发性癌20例临床研究

新医学 1999年第6期30卷 325-326页

作者：何勉黄建昭凌家炜梅卓贤中山医科大学附属第一医院妇产科 510080

目的：提高对子宫内膜癌合并多原发性癌的临床特点的认识。方法：对20例子宫内膜癌合并多原发性癌的临床资料进行回顾性分析。结果：子宫内股癌合并多原发性癌占同期子宫内膜癌的10．9％，其中合并卵巢恶性肿瘤最多见，占50％（10／20... 详细信息

目的：提高对子宫内膜癌合并多原发性癌的临床特点的认识。方法：对20例子宫内膜癌合并多原发性癌的临床资料进行回顾性分析。结果：子宫内股癌合并多原发性癌占同期子宫内膜癌的10．9％，其中合并卵巢恶性肿瘤最多见，占50％（10／20），合并乳腺癌、结／直肠癌者各4例（20％），合并膀胱癌、舌癌各1例。3例多原发性癌发生于子宫内股癌治疗后，6例发生于治疗前，11例同期发生。异期原发癌平均发病间隔时间54个月。结论；子宫内膜癌合并多原发性癌多见于50岁以上患者，生殖系统为其好发部位。

关键词：子宫内膜癌肿瘤多原发性临床研究

Crystal phase-controlled growth of PtCu and PtCo alloys on 4H Au nanoribbons for electrocatalytic ethanol oxidation reaction

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Nano Research 2020年第7期13卷 1970-1975页

作者： Jie Wang Jian Zhang Guigao Liu Chongyi ling Bo Chen Jingtao Huang Xiaozhi Liu Bing Li An-Liang Wang Zhaoning Hu Ming Zhou Ye Chen Hongfei Cheng jiawei Liu Zhanxi Fan Nailiang Yang Chaoliang Tan Lin Gu Jinlan Wang Hua Zhang Department of Chemistry City University of Hong KongHong KongChina Center for Programmable Materials School of Materials Science and EngineeringNanyang Technological University50 Nanyang AvenueSingapore 639798Singapore School of Physics Southeast UniversityNanjing 211189China Institute of Physics Beijing National Laboratory for Condensed Matter PhysicsChinese Academy of SciencesBeijing 100190China Institute of Materials Research and Engineering(IMRE) Agency for Science Technology and Research(A*STAR)Singapore 138634Singapore Hong Kong Branch of National Precious Metals Material Engineering Research Center(NPMM) City University of Hong KongHong KongChina

Crystal phase can greatly affect the physicochemical properties and applications of ***,it stil remains a great challenge to synthesize nanostructures with the same composition and morphology but different phases in order to explore the phase-dependent properties and ***,we report the crystal phase-controlled synthesis of PtCu alloy shells on 4H Au nanoribbons(NRBs),referred to as 4H-Au NRBs,to form the 4H-Au@PtCu core-shell *** tuning the thickness of PtCu,4H-PtCu and face-centered cubic(cc)phase PICu(cc-PtCu)alloy shells are successtully grown on the 4H-Au NRB *** thickness-dependent phase-controlled growth strategy can also be used to grow PtCo alloys with 4H or fcc phase on 4H-Au ***,when used as electrocatalysts for the ethanol oxidation reaction(EOR)in alkaline media,the 4H-Au@4H-PtCu NRBs show much better EOR performance than the 4H-Au@fcc-PtCu NRBs,and both of them possess superior performance compared to the commercial Pt *** study provides a strategy on phase-contolled synthesis of nanomaterials used for crystal phase-dependent applications.

关键词： crystal phase 4H hexagonal face-ce ntered cubic ethanol oxidation reaction phase engineering of nanomaterials

Infectivity of SARS-CoV-2 and protection against reinfection in rats

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Zoological Research 2022年第6期43卷 945-948页

作者： Dandan Yu Yanghaopeng Long ling Xu Jian-Bao Han jiawei Xi Jianlin Xu Lu-Xiu Yang Xiao-Li Feng Qing-Cui Zou Wang Qu Jiangwei Lin Ming-Hua Li Yong-Gang Yao Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650201China Kunming National High-Level Biosafety Research Center for Non-Human Primates Center for Biosafety Mega-ScienceKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China Kunming College of Life Science University of Chinese Academy of SciencesKunmingYunnan 650204China

DEAR EDITOR,The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) pandemic remains an important global public health issue. In this study, we unexpectedly found that wildtype Sprague-Dawley(SD) rats can be infected with the SARS-CoV-2 prototype. Our results showed direct experimental evidence of the infectivity of SARS-CoV-2 infection, subsequent pathogenicity, and protection against reinfection in rats.

关键词： infection rats acute