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Dietary adenosine supplementation improves placental angiogenesis in IUGR piglets by up-regulating adenosine A2a receptor

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Animal Nutrition 2023年第2期13卷 282-288页

作者： Zifang Wu Jiawei Nie Deyuan Wu Shuangbo Huang Jianzhao Chen Huajin Liang Xiangyu Hao Li Feng Hefeng Luo Chengquan Tan Guangdong Provincial Key Laboratory of Animal Nutrition Control National Engineering Research Center for Breeding Swine IndustryInstitute of Subtropical Animal Nutrition and FeedCollege of Animal ScienceSouth China Agricultural UniversityGuangzhouGuangdong 510642China Dekon Food and Agriculture Group ChengduChina

Abnormal placental angiogenesis is associated with the occurrence of intrauterine growth restriction(IUGR)in piglets,and effective treatment strategies against this occurrence remain to be explored.Adenosine has been reported to play an important role in angiogenesis,but its role in placental angio-genesis is still unknown.Here,we investigated the effect of dietary adenosine supplementation on IUGR occurrence in piglets by analyzing the role of adenosine in placental angiogenesis for Normal and IUGR piglets.Specifically,88 sows were allotted to 2 treatments(n=44)and fed a basal diet supplemented with 0%or 0.1%of adenosine from day 65 of gestation until farrowing,followed by collecting the placental samples of Normal and IUGR piglets,and recording their characteristics.The results showed that adenosine supplementation increased the mean birth weight of piglets(P<0.05)and placental efficiency(P<0.05),while decreasing the IUGR piglet rate(P<0.05).Expectedly,the placenta for IUGR neonates showed a down-regulated vascular density(P<0.05)and angiogenesis as evidenced by the expression level of vascular cell adhesion molecule-1(VCAM1)(P<0.05).Notably,dietary adenosine supplementation promoted angiogenesis(P<0.05)both in the Normal and IUGR placenta.More importantly,the expression level of adenosine A2a receptor(ADORA2A)was lower(P<0.05)in the IUGR placenta than in Normal placenta,whereas adenosine treatment could significantly increase ADORA2A expression,and also had an interaction effect between factors IUGR and Ado.Collectively,placentae for IUGR piglets showed impaired angiogenesis and down-regulated expression level of ADORA2A,while dietary adenosine supplementation could activate ADORA2A expression,improve the placental angio-genesis,and ultimately decrease the occurrence of IUGR in piglets.

关键词： Angiogenesis IUGR Placenta Adenosine ADORA2A

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“十七年红色经典”小说评书改编得与失

晋城职业技术学院学报 2024年第3期17卷 79-84页

作者：聂家伟昭通学院人文学院云南昭通657000

《林海雪原》《烈火金钢》《敌后武工队》等“十七年红色经典”小说,由于其传奇性书写,不仅读者众多,很多更是被改编成评书作品。评书中,由于语体的改变和叙事结构的调整,使得改编后对话场景更加生动,故事线索更加清晰,而相关情节的扩... 详细信息

《林海雪原》《烈火金钢》《敌后武工队》等“十七年红色经典”小说,由于其传奇性书写,不仅读者众多,很多更是被改编成评书作品。评书中,由于语体的改变和叙事结构的调整,使得改编后对话场景更加生动,故事线索更加清晰,而相关情节的扩充或删减也都服务于人物的塑造和故事情节的渲染。但也存在改编后破坏主体效果、打乱叙事节奏、前后情节紊乱的问题。本文据此对“十七年红色红典”小说改编的得失与价值进行探讨,以期对“红色经典”小说的当代传播提供借鉴。

关键词：红色经典评书改编语体叙事情节

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浅析工业含铊废水治理技术的研究进展

皮革制作与环保科技 2023年第23期4卷 15-17页

作者：聂佳伟南昌市环保技术服务中心有限公司江西南昌330038

工业废水中的铊污染日益严重,对环境和人类健康构成威胁。本文综述了工业含铊废水治理技术的研究进展,探讨了物理、化学和生物方法在去除铊污染方面的应用。物化联合法和生化联合法等综合技术在工程应用中展现出潜力。同时,膜技术、纳... 详细信息

工业废水中的铊污染日益严重,对环境和人类健康构成威胁。本文综述了工业含铊废水治理技术的研究进展,探讨了物理、化学和生物方法在去除铊污染方面的应用。物化联合法和生化联合法等综合技术在工程应用中展现出潜力。同时,膜技术、纳米材料的引入也为铊污染的治理提供了新思路。然而,多污染物协同效应、实际应用成本等问题仍需克服,所以智能化治理技术和资源化利用被视为未来发展方向,持续研究和创新对于解决工业废水铊污染至关重要。

关键词：工业含铊废水治理技术综合方法环境保护

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激光辐照下CFRP层合板的烧蚀与强度分析

力学季刊 2022年第4期43卷 771-781页

作者：熊刘结王家伟聂国华同济大学航空航天与力学学院上海200092 西北核技术研究院激光与物质相互作用国家重点实验室陕西西安710024

本文以激光辐照下(Carbon Fiber Reinforced Polymer)层合板的烧蚀为基础,进行了激光-机械载荷联合作用下层合板的破坏与强度分析.建立了激光烧蚀模型,确定了在不同强度激光辐照下层合板前后表面以及沿厚度方向的温度场,并通过激光辐照... 详细信息

本文以激光辐照下(Carbon Fiber Reinforced Polymer)层合板的烧蚀为基础,进行了激光-机械载荷联合作用下层合板的破坏与强度分析.建立了激光烧蚀模型,确定了在不同强度激光辐照下层合板前后表面以及沿厚度方向的温度场,并通过激光辐照实验验证了有限元模拟的精度.进一步,根据烧蚀模型和桥联模型,编写了基于Abaqus平台的UMAT子程序,计算获得了激光辐照下CFRP层合板的破坏时间以及拉伸应力应变关系,预测了激光强度和辐照时间等对CFRP层合板拉伸强度的影响规律.本文提出的模型和计算方法对于激光辐照引起烧蚀的复合材料层合结构的强度分析和结构设计具有重要参考价值.

关键词：碳纤维增强复合材料激光烧蚀温度场桥联模型拉伸强度

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回译的类型与意义探究

西南石油大学学报（社会科学版） 2019年第5期21卷 98-105页

作者：聂家伟云南大学文学院

回译有狭义和广义之分,狭义的回译仅指回到原文,而广义的回译还指回到文化。不是所有的翻译都可以纳入到回译范畴,只有汉学著作的翻译和异语原文化写作的翻译涉及到回译。对汉学著作的翻译和异语原文化写作进行回译时会出现三种状况:有... 详细信息

回译有狭义和广义之分,狭义的回译仅指回到原文,而广义的回译还指回到文化。不是所有的翻译都可以纳入到回译范畴,只有汉学著作的翻译和异语原文化写作的翻译涉及到回译。对汉学著作的翻译和异语原文化写作进行回译时会出现三种状况:有本可至译,即可以回译成原语;无本无至译,即只可回译成源语,无原语而只有文化作参照;有本难至译,即本可以回译成原语,但未能找出对应原文,故暂且回译成源语。回译对于语言研究、翻译研究以及教学方法都有辅助作用,但是回译的最大意义却在于文化的馈赠,即:通过回译汉学著作,可以接受西方文化对东方文化的可能馈赠;通过回译异语原文化写作,可以看到东方文化给予西方文化以可能的馈赠。

关键词：有本回译无本回译汉学著作文化馈赠语言研究

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也谈“诗经六义”

语文学刊 2018年第2期38卷 84-90页

作者：聂家伟昭通卫生职业学院云南昭通657000

因其魅力,与《诗经》有关的许多问题争议至今。"诗经六义",历来有三类解释,不过,将"风"、"雅"、"颂"解释为《诗经》的三种体裁,将"赋"、"比"、"兴"解释为三种表现手法,这应该是一个最为可靠的解释。关于"诗经六义"的解读,争议最大的还数... 详细信息

因其魅力,与《诗经》有关的许多问题争议至今。"诗经六义",历来有三类解释,不过,将"风"、"雅"、"颂"解释为《诗经》的三种体裁,将"赋"、"比"、"兴"解释为三种表现手法,这应该是一个最为可靠的解释。关于"诗经六义"的解读,争议最大的还数"赋"、"比"、"兴",朱熹的解读较为合理,只是显得单薄。本文综合各家之言,以期提出一种较为可信的解释。

关键词：诗经六义毛诗序朱熹兴中之比

量测随机丢失下基于容积卡尔曼滤波的厚尾噪声处理方法

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重庆邮电大学学报（自然科学版） 2024年第3期36卷 572-581页

作者：李帅永聂嘉炜郭成春重庆邮电大学工业物联网与网络化控制教育部重点实验室重庆400065

针对量测随机丢失和厚尾量测噪声条件下的非线性状态估计易发散问题,提出了一种新的非线性卡尔曼滤波方法。引入服从Gamma分布的辅助参数,将厚尾量测噪声建模为Student’s t分布,以解决厚尾噪声导致的状态估计易发散问题,并采用服从Benr... 详细信息

针对量测随机丢失和厚尾量测噪声条件下的非线性状态估计易发散问题,提出了一种新的非线性卡尔曼滤波方法。引入服从Gamma分布的辅助参数,将厚尾量测噪声建模为Student’s t分布,以解决厚尾噪声导致的状态估计易发散问题,并采用服从Benroulli分布的随机变量来描述量测信号随机丢失的现象;在量测随机丢失下,基于目标状态和未知参数建立联合后验分布,并使用变分贝叶斯方法,联合估计系统状态、量测丢失概率和未知的厚尾噪声。非线性目标跟踪仿真实验表明,提出的算法可自适应估计未知的量测丢失概率,在野值概率为5%的条件下,算法目标跟踪的位置、速度和转动速率均方根误差分别为对比算法的37%、28%和60%;在野值概率为10%的条件下,其他算法均出现了发散现象,而提出的算法依然能够以较低的误差跟踪目标,体现了所提算法良好的鲁棒性和优越性。

关键词：非线性状态估计量测随机丢失厚尾噪声 Student’s t分布变分贝叶斯

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液氧煤油发动机伺服机构回路频率提升研究

Aerospace China 2023年第3期24卷 18-25页

作者： WANG Ke HE Jiang LI Miaoting nie jiawei Xi’an Aerospace Propulsion Institute Xi’an 710100

In order to suppress the low-frequency resonance phenomenon in the engine-servo loop during the development of the 1200 kN LOX/kerosene engine,the inherent characteristics of the loop were analyzed by finite element simulation and experiment.Based on the method of finite element simulation,the modal analysis of the engine-servo loop was carried out,and the finite element model was modified according to the results of modal test,so that the results of finite element simulation were in agreement with the results of the modal test.On this basis,various sensitive factors were analyzed with the finite element software.The results show that the stiffness of the bearing and gimbal mount as well as the stiffness and dip angle of the pull rod have great influence on the natural frequency of the engine.Based on these conclusions,the structure of the engine was improved.The modal analysis of the improved single-engine and double-engine structures was carried out using numerical simulation and modal test.The results show that the low-order frequency of the improved single-engine and double-engine structures was significantly improved,and the effectiveness of the improved scheme was verified,which provides a solution to improve the low-order natural frequency in the engine-servo loop.

关键词： LOX/kerosene engine engine-servo loop low-order frequency characteristics modal analysis

液氧煤油发动机伺服机构回路频率提升研究（英文）

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Aerospace China 2023年第3期 18-25页

作者： WANG Ke HE Jiang LI Miaoting nie jiawei Xi’an Aerospace Propulsion Institute

In order to suppress the low-frequency resonance phenomenon in the engine-servo loop during the development of the 1200 k N LOX/kerosene engine, the inherent characteristics of the loop were analyzed by finite element simulation and experiment. Based on the method of finite element simulation, the modal analysis of the engine-servo loop was carried out, and the finite element model was modified according to the results of modal test, so that the results of finite element simulation were in agreement with the results of the modal test. On this basis, various sensitive factors were analyzed with the finite element software. The results show that the stiffness of the bearing and gimbal mount as well as the stiffness and dip angle of the pull rod have great influence on the natural frequency of the engine. Based on these conclusions, the structure of the engine was improved. The modal analysis of the improved single-engine and double-engine structures was carried out using numerical simulation and modal test. The results show that the low-order frequency of the improved single-engine and double-engine structures was significantly improved, and the effectiveness of the improved scheme was verified, which provides a solution to improve the low-order natural frequency in the engine-servo loop.

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