检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

纳米材料在病毒检测中的应用研究进展

材料导报 2023年第6期37卷 36-46页

作者：李佳炜朱宏伟清华大学材料学院新型陶瓷与精细工艺国家重点实验室北京100084

病毒的快速、灵敏和特异性检测是医学领域备受关注的关键问题。自2020年以来,新型冠状病毒肺炎疫情在全球范围内的爆发对快捷灵敏的病毒检测方法提出了更高要求。随着新材料尤其是纳米材料的不断发展,很多材料显示出优异的物理、化学与... 详细信息

病毒的快速、灵敏和特异性检测是医学领域备受关注的关键问题。自2020年以来,新型冠状病毒肺炎疫情在全球范围内的爆发对快捷灵敏的病毒检测方法提出了更高要求。随着新材料尤其是纳米材料的不断发展,很多材料显示出优异的物理、化学与力学性能,在病毒检测中展现出应用潜力。纳米材料从结构上可分为零维材料、一维材料与二维材料。本文从病毒检测基本方法入手,围绕纳米材料的分类,结合纳米材料的最新进展,综述了各类纳米材料在病毒探测领域的应用,对其未来发展趋势进行了展望。

关键词：纳米材料病毒检测生物传感器化学传感器

Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 533-547页

作者： Yanli Zhang Tian li Jie Miao Zhina Zhang Mingxuan Yang Zhuoran Wang Bo Yang jiawei Zhang Haiting li Qiang Su Junhong Guo Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina Department of Physiology Key Laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Hernia and Abdominal Wall Surgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine of Fenyang College Shanxi Medical UniversityFenyangShanxi ProvinceChina

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial ***,the functional role of GGT5 in the development of Alzheimer’s disease remains *** study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying *** observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse ***,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive ***,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 *** effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa *** findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 *** findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β APP/PS1 mice cerebrovascular endothelial cells cognitive deficits gamma-glutamyl transferase 5 neurovascular unit nuclear factor‐kappa B synaptic plasticity β-site APP cleaving enzyme 1

Point attention network for point cloud semantic segmentation

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2022年第9期65卷 99-112页

作者： Dayong REN Zhengyi WU jiawei li Piaopiao YU Jie GUO Mingqiang WEI Yanwen GUO National Key Lab for Novel Software Technology Nanjing University School of Computer Science and Technology Nanjing University of Aeronautics and Astronautics

We address the point cloud semantic segmentation problem through modeling long-range dependencies based on the self-attention mechanism. Existing semantic segmentation models generally focus on local feature aggregation. By comparison, we propose a point attention network(PA-Net) to selectively extract local features with long-range dependencies. We specially devise two complementary attention modules for the point cloud semantic segmentation task. The attention modules adaptively integrate the semantic inter-dependencies with long-range dependencies. Our point attention module adaptively integrates local features of the last layer of the encoder with a weighted sum of the long-range dependency features. Regardless of the distance of similar features, they are all correlated with each other. Meanwhile, the feature attention module adaptively integrates inter-dependent feature maps among all local features in the last layer of the encoder. Extensive results prove that our two attention modules together improve the performance of semantic segmentation on point clouds. We achieve better semantic segmentation performance on two benchmark point cloud datasets(i.e., S3DIS and Scan Net). Particularly, the Io U on 11 semantic categories of S3DIS is significantly boosted.

关键词： point cloud semantic segmentation self-attention mechanism deep learning long-range dependencies

同方期刊数据库

Development of Features for Early Detection of Defects and Assessment of Bridge Decks

在线全文

学校读者我要写书评

暂无评论

Structural Durability & Health Monitoring 2023年第4期17卷 257-281页

作者： Ahmed Silik Xiaodong Wang Chenyue Mei Xiaolei Jin Xudong Zhou Wei Zhou Congning Chen Weixing Hong jiawei li Mingjie Mao Yuhan liu Mohammad Noori Wael A.Altabey Nanjing Zhixing Information Technology Co. Ltd.NanjingChina Jiangsu Advance Transportation Institute NanjingChina Suzhou Highway Development Center SuzhouChina Guangdong Communications Group Co. Ltd.GuangzhouChina Department of Mechanical Engineering California Polytechnic State UniversitySan Luis ObispoCA93405USA School of Civil Engineering University of LeedsLeedsLS29JTUK Department of Civil Engineering Faculty of Engineering SciencesNyala UniversityNyala092Sudan Department of Mechanical Engineering Faculty of EngineeringAlexandria UniversityAlexandria21544Egypt

Damage detection is an important area with growing interest in mechanical and structural *** of the critical issues in damage detection is how to determine indices sensitive to the structural damage and insensitive to the surrounding environmental *** damage identification indices commonly focus on structural dynamic characteristics such as natural frequencies,mode shapes,and frequency *** study aimed at developing a technique based on energy Curvature Difference,power spectrum density,correlation-based index,load distribution factor,and neutral axis shift to assess the bridge deck *** addition to tracking energy and frequency over time using wavelet packet transform,in order to further demonstrate the feasibility and validity of the proposed technique for bridge condition assessment,experimental strain data measured from two stages of a bridge in the different intervals were *** comparative analysis results of the bridge in first and second stage show changes in the proposed feature *** is concluded,these changes in the values of the proposed features can be used to assess the bridge deck performance.

关键词： Structural health monitoring strain monitoring distribution factor wavelet packet transform

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

星地相干光通信中的自适应光学系统带宽研究

中国激光 2016年第8期43卷 242-247页

作者：李佳蔚陈卫标中国科学院上海光学精密机械研究所空间激光信息传输与探测技术重点实验室上海201800 中国科学院大学北京100049

针对星地相干激光通信,研究了自适应光学的系统带宽对通信性能的影响。对于特定校正阶数的自适应光学系统,得到了系统需求的控制带宽,并对比了同步轨道(GEO)卫星对地链路和低地轨道(LEO)卫星对地链路。结果显示低轨卫星链路所需的控制... 详细信息

针对星地相干激光通信,研究了自适应光学的系统带宽对通信性能的影响。对于特定校正阶数的自适应光学系统,得到了系统需求的控制带宽,并对比了同步轨道(GEO)卫星对地链路和低地轨道(LEO)卫星对地链路。结果显示低轨卫星链路所需的控制带宽远大于同步卫星链路,原因来自于低轨卫星和地面站的高速相对运动产生的垂直链路风速,同时低轨卫星对地链路对自适应光学的带宽需求和天顶角是成反比关系的。分析了低轨卫星对地相干激光通信链路混频效率和自适应系统带宽以及校正阶数的关系,结果表明,200 Hz的闭环带宽完全可以满足需求,当达到100Hz带宽之后,增加变形镜单元数对混频效率的提升更为有效。

关键词：光通信自适应光学大气湍流控制带宽混频效率

Influences of the Preparation Techniques on Glass Forming Ability of Fe–P–B–Si–C Amorphous Alloys

在线全文

学校读者我要写书评

暂无评论

Influences of the Preparation Techniques on Glass Forming Ab...

经验的出场:本雅明对历史唯物主义的最初接受

第十一届中国钢铁年会

作者： Zhang Jijun Dong Yaqiang Bie Luyang li Qiang li jiawei Wang Xinmin Key Laboratory of Magnetic Materials and Devices Ningbo Institute of Materials Technology & EngineeringChinese Academy of Sciences Zhejiang Province Key Laboratory of Magnetic Materials and Application Technology Ningbo Institute of Materials Technology & Engineering Chinese Academy of Sciences University of Chinese Academy of Sciences School of Physics Science and Technology Xinjiang University

In contrast to the ultrahigh cooling rate that is required to for glass formation, larger glass forming ability(GFA) is achieved at lower cooling rate in FeP(BSiC) synthesized in argon *** rods with diameters of 1 to 2 mm are prepared by water quenching without flux treatment, Cu-mold injection casting and Cu-mold suction casting, *** influences of the preparation techniques with different cooling rates on GFA, thermal property and nucleation/growth behavior are *** critical diameter of FeP(BSiC) amorphous alloys is 1.7 mm for water quenchingwhile smaller than 1 mm for injection *** analysis indicates that the crystallization and solidification processes are quite different between the water-quenched and the injection casted *** finding provides fundamental understanding on the relationship between the cooling rate, techniques and glass forming ability of Fe-based amorphous alloys.

关键词： Fe-based amorphous alloys preparation techniques glass forming ability crystallization behaviors

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

教学与研究 2022年第3期 107-116页

作者：李佳玮中国人民大学哲学院北京100872

本雅明作为西方马克思主义重要的思想家之一对历史唯物主义的阐释做出了重要贡献,丰富了历史唯物主义的理论活力。但是长期以来,由于他的神学阐释方式和思想中的神学因素,使其马克思主义者的身份形象晦暗不明,本文尝试着眼于本雅明的思... 详细信息

本雅明作为西方马克思主义重要的思想家之一对历史唯物主义的阐释做出了重要贡献,丰富了历史唯物主义的理论活力。但是长期以来,由于他的神学阐释方式和思想中的神学因素,使其马克思主义者的身份形象晦暗不明,本文尝试着眼于本雅明的思想转型的关键节点对这一问题给予回答。从本雅明接触历史唯物主义开始到对其做出新的阐释中间经历了一段理论成长期,经验概念在这段时期扮演了极为重要的角色,而他在早期围绕经验概念所做的相关论述更是其与历史唯物主义最早产生思想交集的关键证据。通过早期关于经验问题的两个文本群可以分析出本雅明与历史唯物主义发生关联的思想契机和神学语言观中潜存的历史唯物主义感知模式,找到本雅明理解和阐释历史唯物主义的观念来源,从而进一步澄明本雅明的思想形象,理解本雅明与马克思主义之间的关系,重新定义本雅明在西方马克思主义理论谱系中的地位。

关键词：马克思主义历史唯物主义本雅明经验青年

在线全文

学校读者我要写书评

暂无评论

“全球南方”概念的规范价值及其限度分析

国际论坛 2024年第3期26卷 119-137,159,160页

作者：李嘉伟中国人民大学国际关系学院北京100872

相比于作为实体的发展中国家群体性兴起,“全球南方”这一术语本身的兴起是新近出现的经验现象。“全球南方”是一个带有规范价值的术语,但其规范意义常被忽视,而“全球南方”兴起的限度,也在于其规范价值所呈现的愿景与现实的张力。“... 详细信息

相比于作为实体的发展中国家群体性兴起,“全球南方”这一术语本身的兴起是新近出现的经验现象。“全球南方”是一个带有规范价值的术语,但其规范意义常被忽视,而“全球南方”兴起的限度,也在于其规范价值所呈现的愿景与现实的张力。“全球南方”的自主性价值体现在,“全球南方”突出了全球化时代发展中国家对依附状态的反抗,追求独立自主的愿景;其限度在于,“全球南方”中的多数中小国家在国际体系中无法实现完全的“自助”,发展上受依附式发展的限制,安全上受全球联盟体系的约束。“全球南方”的变革性价值体现在,“全球南方”不局限于行为体之间的关系,而是要求变革西方主导下的等级制世界秩序;其限度在于,一些全球南方国家的行为与反对等级制的愿景相违背,在全球层面进行零和性质的地位追求,在地区层面试图建立地区等级制。“全球南方”的集体性价值体现在,“全球南方”以反帝反殖民的共同命运为基础,在成员之间构建集体身份、实现集体行动;其限度在于,“全球南方”与群体外“北方”的趋同和群体内的分异。明晰“全球南方”这一术语的规范价值及其限度,在学理上可以更好地区分“全球南方”与相似概念并从规范的视角看待其兴起的价值及其限制;在现实上有助于我国应对美西方将中国排除出“全球南方”的图谋,更好地团结广大全球南方国家,推动全球正义的实现和国际秩序进一步平等化。

关键词：全球南方发展中国家国际等级制规范价值

极端事件真的能塑造投资者预期?——基于“坏β”“好β”资产定价理论的实证检验

在线全文

学校读者我要写书评

暂无评论

经济学（季刊） 2013年第4期12卷 151-174页

作者：李家伟国海证券股份有限公司

本文发现Campbell and Vuolteenaho(2004)的"坏β""好β"理论对价值异象的解释具有很强的样本依赖性。我们在现有文献的基础上构建了具有经济直觉的理论假设和基于市场的经验方法,检验了这种样本敏感性问题的理论合理性。结果显示,该样... 详细信息

本文发现Campbell and Vuolteenaho(2004)的"坏β""好β"理论对价值异象的解释具有很强的样本依赖性。我们在现有文献的基础上构建了具有经济直觉的理论假设和基于市场的经验方法,检验了这种样本敏感性问题的理论合理性。结果显示,该样本敏感性问题不具备理论上的合理性,从而原文中经验发现的可靠性是值得怀疑的。本文进一步的研究结果显示,原文基于VAR信息分解方法的"坏β""好β"模型也不能很好地解释股票回报的横切面。

关键词：资产定价极端事件价值异象