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Journal of Energy Chemistry 2023年第6期81卷 125-131,I0005页

作者： Chunfeng Cheng Tianfu Liu Yi Wang Pengfei Wei jiaqi Sang jiaqi shao Yanpeng Song Yipeng Zang Dunfeng Gao Guoxiong Wang State Key Laboratory of Catalysis Dalian National Laboratory for Clean EnergyiChEM(Collaborative Innovation Center of Chemistry for Energy Materials)Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina University of Chinese Academy of Sciences Beijing 100049China

Simultaneously achieving high activity,selectivity and stability for electrochemical CO_(2)reduction reaction(CO_(2)RR)remains great ***,a phosphorus-modified Sn/Sn Oxcore/shell(P-Sn/SnO_x)catalyst,derived from in situ electrochemical reduction of an amorphous Sn(HPO_(4))_(2) pre-catalyst,exhibits high CO_(2)RR *** total Faradaic efficiency(FE)of C_(1) products is close to 100%in a broad potential range from-0.49 to-1.02 V *** hydrogen electrode,and a total current density of 315.0 m A cm^(-2)is ***,the P-Sn/SnO_(x) catalyst maintains a formate FE of~90%for 120 *** functional theory calculations suggest that the phosphorus-modified Sn/SnO_(x) core/shell structure effectively facilitates formate production by enhancing CO_(2)adsorption and improving free energy profile of formate formation.

关键词： CO_(2)electroreduction Structural evolution Reaction intermediate Phosphorus modification Stability

Application of U-Net and Optimized Clustering in Medical Image Segmentation:A Review

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Computer Modeling in Engineering & Sciences 2023年第9期136卷 2173-2219页

作者： jiaqi shao Shuwen Chen Jin Zhou Huisheng Zhu Ziyi Wang Mackenzie Brown School of Physics and Information Engineering Jiangsu Second Normal UniversityNanjing211200China State Key Laboratory of Millimeter Waves Southeast UniversityNanjing210096China Jiangsu Province Engineering Research Center of Basic Education Big Data Application Nanjing211200China School of Data Science Perdana UniversitySerdangSelangor43400Malaysia

As a mainstream research direction in the field of image segmentation,medical image segmentation plays a key role in the quantification of lesions,three-dimensional reconstruction,region of interest extraction and so *** with natural images,medical images have a variety of ***,the emphasis of information which is conveyed by images of different modes is quite *** it is time-consuming and inefficient to manually segment medical images only by professional and experienced ***,large quantities of automated medical image segmentation methods have been ***,until now,researchers have not developed a universal method for all types of medical image *** paper reviews the literature on segmentation techniques that have produced major breakthroughs in recent *** the large quantities of medical image segmentation methods,this paper mainly discusses two categories of medical image segmentation *** is the improved strategies based on traditional clustering *** other is the research progress of the improved image segmentation network structure model based on *** power of technology proves that the performance of the deep learning-based method is significantly better than that of the traditional *** paper discussed both advantages and disadvantages of different algorithms and detailed how these methods can be used for the segmentation of lesions or other organs and tissues,as well as possible technical trends for future work.

关键词： Medical image segmentation clustering algorithm U-Net

NudCL2 is required for cytokinesis by stabilizing RCC2 with Hsp90 at the midbody

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Protein & Cell 2024年第10期15卷 766-782页

作者： Xiaoyang Xu Yuliang Huang Feng Yang Xiaoxia Sun Rijin Lin Jiaxing Feng Mingyang Yang jiaqi shao Xiaoqi Liu Tianhua Zhou Shanshan Xie Yuehong Yang Department of Cell Biology Institute of Gastroenterology of the Second Affliated HospitalZhejiang University School of MedicineHangzhou 310009China Research Center for Children's Health and Innovation Binjiang Institute of Zhejiang UniversityHangzhou 310053China Department of Biochemistry Purdue UniversityWest LafayetteIN 47907United States Cancer Center Zhejiang UniversityHangzhou 310058China Center for RNA Medicine International Institutes of Medicinethe Fourth Affliated Hospital of Zhejiang University School of MedicineYiwu 322000China Children's Hospital Zhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052China

Cytokinesis is required for faithful division of cytoplasmic components and duplicated nuclei into two daughter ***,a protein-dense organelle that forms at the intercellular bridge,is indispensable for success-ful ***,the regulatory mechanism of cytokinesis at the midbody still remains ***,we unveil a critical role for NudC-like protein 2(NudCL2),a co-chaperone of heat shock protein 90(Hsp90),in cytokinesis regulation by stabilizing regulator of chromosome condensation 2(RCC2)at the midbody in mam-malian ***2 localizes at the midbody,and its downregulation results in cytokinesis failure,multinu-cleation,and midbody *** iTRAQ-based quantitative proteomic analysis,we find that RCC2 levels are decreased in NudCL2 knockout(KO)***,Hsp90 forms a complex with NudCL2 to stabilize RCC2,which is essential for ***2 depletion mirrors phenotypes observed in NudCL2-downregulated ***,ectopic expression of RCC2 rescues the cytokinesis defects induced by NudCL2 deletion,but not vice ***,our data reveal the significance of the NudCL2/Hsp90/RCC2 pathway in cytokinesis at the midbody.

关键词： cytokinesis midbody NudCL2 Hsp90 RCC2

Copper-indium bimetallic catalysts for the selective electrochemical reduction of carbon dioxide

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Chinese Journal of Catalysis 2020年第9期41卷 1393-1400页

作者： jiaqi shao Yi Wang Dunfeng Gao Ke Ye Qi Wang Guoxiong Wang Key Laboratory of Superlight Materials and Surface Technology of Ministry of Education College of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001HeilongjiangChina State Key Laboratory of Catalysis Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina Liaoning Key Materials Laboratory for Railway School of Materials and EngineeringDalian Jiaotong UniversityDalian 116028LiaoningChina

Copper-indium bimetallic catalysts with a dendritic structure are fabricated by a two-step electrodeposition method using a hydrogen evolution template for the CO2 electroreduction reaction(CO2RR).The dendritic Cu-In-30 catalyst electrodeposited for 30 min shows the highest specific surface area and exposes the most active sites,resulting in improved CO2RR *** dendritic Cu-In-30 catalyst exhibits distinctly higher formate partial current density(42.0 m A cm^-2)and Faradaic efficiency(87.4%)than those of the In-30 catalyst without the dendritic structure(the formate partial current density and Faradaic efficiency are 4.6 m A cm^-2 and 57.0%,respectively)at-0.85 V *** hydrogen electrode,ascribed to the increased specific surface *** Cu-In-30 catalyst can maintain stable performance for 12 h during the *** addition,the intrinsic current density of Cu-In-30 with the dendritic structure(4.8 m A cm^-2)is much higher than that of In-30 without the dendritic structure(2.1 m A cm^-2),indicating that the dendritic structure promotes the CO2RR,possibly due to additional coordination unsaturated atoms.

关键词： CO2 electroreduction reaction Copper Indium Electrodeposition Formate

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巨噬细胞力学信号转导通路的研究进展

医用生物力学 2023年第2期38卷 408-414页

作者：邵佳琦李娟林军浙江大学医学院附属第一医院口腔科杭州310003

微环境中的机械力学刺激(如基质刚度、表面形貌、循环牵张),通过细胞膜上受体为巨噬细胞所感知,可沿着黏附蛋白分子链和细胞骨架向细胞核内传递,并转导为生化信号激活基因转录。机械力学刺激驱动巨噬细胞的黏附、增殖、迁移、极化等生... 详细信息

微环境中的机械力学刺激(如基质刚度、表面形貌、循环牵张),通过细胞膜上受体为巨噬细胞所感知,可沿着黏附蛋白分子链和细胞骨架向细胞核内传递,并转导为生化信号激活基因转录。机械力学刺激驱动巨噬细胞的黏附、增殖、迁移、极化等生物学行为,在疾病进展和组织再生中发挥相应作用。本文论述微环境中机械力学刺激对巨噬细胞表型和功能的影响,阐明巨噬细胞机械转导通路的相关机制,为靶向巨噬细胞的免疫调节型生物材料研发提供分子生物力学的新思路。

关键词：生物力学力学转导巨噬细胞极化生物材料

Synergy effects on Sn-Cu alloy catalyst for efficient CO2 electroreduction to formate with high mass activity

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Science Bulletin 2020年第9期65卷 711-719,M0003页

作者： Ke Ye Ang Cao jiaqi shao Gang Wang Rui Si Na Ta Jianping Xiao Guoxiong Wang State Key Laboratory of Catalysis Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China Key Laboratory of Superlight Materials and Surface Technology of Ministry of Education College of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China Shanghai Synchrotron Radiation Facility Zhangjiang LaboratoryShanghai 201204China

To acquire the synergy effects between Sn and Cu for the jointly high Faradaic efficiency and current density,we develop a novel strategy to design the Sn-Cu alloy catalyst via a decorated co-electrodeposition method for CO2 electroreduction to *** Sn-Cu alloy shows high formate Faradaic efficiency of 82.3%±2.1% and total C1 products Faradaic efficiency of 90.0%±2.7% at^-1.14 V *** hydrogen electrode(RHE).The current density and mass activity of formate reach as high as(79.0±0.4)mA cm^-2 and(1490.6±7.5)m A mg^-1 at^-1.14 V *** calculations suggest that Sn-Cu alloy can obtain high Faradaic efficiency for CO2 electroreduction by suppressing the competitive hydrogen evolution reaction and that the formate formation follows the path of CO2→HCOO*→*** stepped(211)surface of Sn-Cu alloy is beneficial towards selective formate production.

关键词： Electrochemical carbon dioxide reduction reaction Synergy effects Sn-Cu alloy Mass activity Formate

线性APD混合飞行时间测距模型及读出电路设计

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红外与激光工程 2023年第9期52卷 86-95页

作者：邵家起陈洪雷丁瑞军中国科学院上海技术物理研究所红外成像材料与器件重点实验室上海200083 上海科技大学信息科学与技术学院上海200120 中国科学院大学北京100049

混合飞行时间测距基于间接飞行时间测距的原理,同时结合直接飞行时间测距的概念,可以实现高精度、高范围的脉冲激光测距。采用两相采集方式,建立了背景光抑制的两段两相混合测距模型,并通过对模型的误差分析确定了电路的相关参数。采用... 详细信息

混合飞行时间测距基于间接飞行时间测距的原理,同时结合直接飞行时间测距的概念,可以实现高精度、高范围的脉冲激光测距。采用两相采集方式,建立了背景光抑制的两段两相混合测距模型,并通过对模型的误差分析确定了电路的相关参数。采用在线性模式下工作的雪崩光电二极管(Linear-Mode APD,LM-APD)作为探测器,设计了与混合测距模型适配的50μm中心距的像素电路以及5×5阵列结构。电路输入级采用电容反馈跨阻放大器结构,输出信号包括模拟信号和低压差分信号。在对APD探测器20 MHz的调制频率下,输出电压达到99.8%以上的线性度,在108.75 m测距范围内达到4.415 cm的平均误差,11.355 cm的最大误差。仿真表明:混合测距兼顾精度和测量范围,适用于激光雷达三维成像领域。

关键词：混合飞行时间测距读出电路线性模式雪崩光电二极管激光雷达

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太阳能无人机线性自抗扰多环路能源控制

航空学报 2023年第10期44卷 271-283页

作者：邵嘉琪张晓辉席涵宇刘子荣北京理工大学宇航学院北京100081

针对太阳能无人机的太阳能/锂电池混合能源系统高能效管理与控制问题,提出了一种基于线性自抗扰控制(LADRC)的多环路控制方法,动态控制能源系统电压/电流,实现太阳能高效利用的同时,避免锂电池过度充电。其核心思想是采用LADRC方法主动... 详细信息

针对太阳能无人机的太阳能/锂电池混合能源系统高能效管理与控制问题,提出了一种基于线性自抗扰控制(LADRC)的多环路控制方法,动态控制能源系统电压/电流,实现太阳能高效利用的同时,避免锂电池过度充电。其核心思想是采用LADRC方法主动消除系统扰动,提高控制器鲁棒性和稳定性,快速稳定响应太阳能无人机机动过程辐照和载荷动态变化;设计最大功率点跟踪(MPPT)环路、稳压环路和限流环路联合控制方法,实现能源管理控制器多个状态量同时控制;通过引入竞争机制,解决控制器工作模式频繁跳变问题。首先,建立了用于MPPT环路控制的LADRC控制器模型,与PI方法进行了动态响应对比测试。然后,搭建了太阳能机翼所受辐照与飞行姿态耦合的太阳能/锂电池混合能源控制试验平台,对所提出的多环路控制方法进行八边形航线飞行模拟测试。最后,试验结果表明:相比于PI方法,基于LADRC方法的多环路控制系统的最大功率点跟踪时间可减少40%~70%,且控制系统更加稳定,瞬态响应加快;在飞行模拟测试过程中,所提多环路控制方法能够根据飞行载荷和电池电量状态平滑切换控制器工作模式,使光伏系统始终以最佳能效输出,研究结果可以为太阳能无人机的高能效飞行提供一种理论基础和工程技术支持。

关键词：太阳能无人机混合动力能源控制策略多环路控制线性自抗扰控制

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气候变化背景下中国玉米生产潜力变化特征

地理科学进展 2020年第3期39卷 443-453页

作者：周美君李飞邵佳琪杨海娟西北大学城市与环境学院西安710127 陕西省地表过程与环境承载力重点实验室西安710127

玉米作为中国第一大粮食作物,探究其生产潜力在气候变化背景下的时空变化特征对中国有效应对气候变化具有重要意义。论文结合全球农业生态区模型、极点对称模态分解方法和集对分析方法,探讨了中国玉米生产潜力的周期性波动特征及长期变... 详细信息

玉米作为中国第一大粮食作物,探究其生产潜力在气候变化背景下的时空变化特征对中国有效应对气候变化具有重要意义。论文结合全球农业生态区模型、极点对称模态分解方法和集对分析方法,探讨了中国玉米生产潜力的周期性波动特征及长期变化趋势,进而分析了其空间格局演变过程。结果表明:1960—2010年间,中国玉米生产潜力呈增加趋势,由1960年代的9.10亿t增至2000年代的9.45亿t左右。在年际尺度上,中国玉米生产潜力主要以准3 a和准5 a的周期进行波动;在年代际尺度上,存在准10 a和准20 a的波动周期。其中,准3 a的周期波动是中国玉米生产潜力长时间变化的最主要特征,这主要是受年降水量变化的影响。从空间格局来看,中国玉米生长适宜区主要集中在加格达奇—锡林浩特—临河—西宁—天水—中甸沿线以东;1960—2000年间,玉米生产潜力界线在中国东北部和临河—西宁沿线发生了较为明显的移动。华北平原、辽河平原、四川盆地等地区的玉米单产潜力变化趋势具有较强的一致性,松嫩平原、三江平原、关中盆地、长江中下游平原等地区的玉米单产潜力变化过程与上述地区恰好相反。在这2类地区,玉米单产潜力的变化均较显著,但变化方向在年代际尺度上具有交替性。

关键词：玉米生产潜力周期性空间格局气候变化中国

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张应力、Runx2表达与髁突发育

口腔医学研究 2022年第11期38卷 1022-1025页

作者：邵佳琪卢海平浙江中医药大学口腔医学院浙江杭州310000

下颌髁突软骨为下颌骨生长发育的重要生长区之一,其生长发育受多种因素影响,研究认为张应力作用可促进髁突软骨内成骨,而Runx2基因表达与髁突软骨内成骨也密切相关。本文就张应力及Runx2表达与髁突发育之间的研究进展做一综述。

关键词：张应力 Runx2 髁突