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Flexible,high-density,laminated ECoG electrode array for high spatiotemporal resolution foci diagnostic localization of refractory epilepsy

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Bio-Design and Manufacturing 2024年第4期7卷 388-398页

作者： Yafeng Liu Zhouheng Wang Yang jiao Ying Chen Guangyuan Xu Yinji Ma Xue Feng Applied Mechanics Laboratory Department of Engineering MechanicsTsinghua UniversityBeijing 100084China Laboratory of Flexible Electronics Technology Tsinghua UniversityBeijing 100084China College of Artificial Intelligence Southwest UniversityChongqing 400715China Institute of Flexible Electronics Technology of THU Jiaxing 314000China Qiantang Science and Technology Innovation Center Hangzhou 310016China School of Artificial Intelligence Beijing University of Posts and TelecommunicationsBeijing 100876China

High spatiotemporal resolution brain electrical signals are critical for basic neuroscience research and high-precision focus diagnostic localization,as the spatial scale of some pathologic signals is at the submillimeter or micrometer *** entails connecting hundreds or thousands of electrode wires on a limited *** study reported a class of flexible,ultrathin,highdensity electrocorticogram(ECoG)electrode *** challenge of a large number of wiring arrangements was overcome by a laminated structure design and processing technology *** flexible,ultrathin,high-density ECoG electrode array was conformably attached to the cortex for reliable,high spatial resolution electrophysiologic *** minimum spacing between electrodes was 15μm,comparable to the diameter of a single *** hundred electrodes were prepared with an electrode density of 4444 mm^(-2).In focal epilepsy surgery,the flexible,high-density,laminated ECoG electrode array with 36 electrodes was applied to collect epileptic spike waves inrabbits,improving the positioning accuracy of epilepsy lesions from the centimeter to the submillimeter *** flexible,high-density,laminated ECoG electrode array has potential clinical applications in intractable epilepsy and other neurologic diseases requiring high-precision electroencephalogram acquisition.

关键词： Electrocorticogram(ECoG)electrode Epilepsy High density High resolution Laminated structure

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Development of multi-functional anchorage support dynamic-static coupling performance test system and its application

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International Journal of Mining Science and Technology 2024年第3期34卷 339-349页

作者： Qi Wang Shuo Xu Bei Jiang Chong Zhang Zhe Sun Jingxuan Liu Cailin jiao State Key Laboratory for Tunnel Engineering China University of Mining&Technology-BeijingBeijing 100083China Research Center of Geotechnical and Structural Engineering Shandong UniversityJinan 250061China

In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses and strong disturbances and construction conditions such as the application of high *** is essential to study the support components performance under dynamic-static coupling *** on this,a multi-functional anchorage support dynamic-static coupling performance test system(MAC system)is developed,which can achieve 7 types of testing functions,including single component performance,anchored net performance,anchored rock performance and so *** bolt and cable mechanical tests are conducted by MAC system under different prestress *** results showed that compared to the non-prestress condition,the impact resistance performance of prestressed bolts(cables)is significantly *** the prestress range of 50–160 k N,the maximum reduction rate of impact energy resisted by different types of bolts is 53.9%–61.5%compared to non-prestress *** the prestress range of 150–300 k N,the impact energy resisted by high-strength cable is reduced by76.8%–84.6%compared to non-prestress *** MAC system achieves dynamic-static coupling performance test,which provide an effective means for the design of anchorage support system.

关键词： Anchorage support system Development of test system Dynamic-static coupling test Combined stress

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A column-shared histogramming TDC with pixel-to-pixel coincidence detection and compact analog counters for Flash LiDAR sensor

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Science China(Information Sciences) 2024年第8期67卷 345-346页

作者： Haoran WU Kaiming NIE Jiangtao XU Qinglong LIN Yingying jiao School of Microelectronics Tianjin University Tianjin Key Laboratory of Imaging and Sensing Microelectronic Technology

In recent years, Flash LiDAR sensors based on direct timeof-flight(DToF) have been playing an increasingly important role in various 3D imaging fields. In order to perform a histogram on the chip to reduce the data rate, it is inevitable to use a large-size histogramming time-to-digital converter(hTDC) in a Flash LiDAR sensor. However, a large-size hTDC limits the spatial resolution of the sensor.

关键词： Pixels

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Physiological,transcriptome and gene functional analysis provide novel sights into cadmium accumulation and tolerance mechanisms in kenaf

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Journal of Environmental Sciences 2024年第3期137卷 500-514页

作者： Shan Cao Meng Wang jiao Pan Dengjie Luo Samavia Mubeen Caijin Wang jiao Yue Xia Wu Qijing Wu Hui Zhang Canni Chen Muzammal Rehman Sichen Xie Ru Li Peng Chen Guangxi Key Laboratory of Agro-environment and Agric-products safety Key Laboratory of Plant Genetics and BreedingCollege of AgricultureGuangxi UniversityNanning 530004China State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources College of Life Science and TechnologyGuangxi UniversityNanning 530004China

Kenaf is considered to have great potential for remediation of heavy metals in ***,studies on molecular mechanisms of root Cd accumulation and tolerance are still *** this study,two differently tolerant kenaf cultivars were selected as materials and the physiological and transcriptomic effects were evaluated under Cd *** study showed that 200μmol/L CdCl_(2) treatment triggered the reactive oxygen species(ROS)explosion and membrane lipid *** with the Cd-sensitive cultivar‘Z',the Cd-tolerant cultivar‘F'was able to resist oxidative stress in cells by producing higher antioxidant enzyme activities and increasing the contents of ascorbic acid(AsA)and glutathione(GSH).The root cell wall of‘F'exhibited higher polysaccharide contents under Cd treatment,providing more Cd-binding *** were 3,439 differentially expressed genes(DEGs)that were co-regulated by Cd treatment in two *** biosynthesis and plant hormone signal transduction pathways were significantly enriched by functional annotation *** associated with pectin,cellulose,and hemi-cellulose metabolism were involved in Cd chelation of root cell wall;V-ATPases,ABCC3 and Narmp3 could participated in vacuolar compartmentalization of Cd;PDR1 was responsible for Cd effux;the organic acid transporters contributed to the absorption of Cd in *** genes might have played key roles in kenaf Cd tolerance and Cd ***,HcZIP2 was identified to be involved in Cd uptake and transport in *** findings provide a deeper understanding of the molecular pathways underlying Cd accumulation and detoxification mechanisms in kenaf.

关键词： Kenaf Cd stress Physiological Transcriptome HcZIP2

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Antibodies elicited by Newcastle disease virus-vectored H7N9 avian influenza vaccine are functional in activating the complement system

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Journal of Integrative Agriculture 2024年第6期23卷 2052-2064页

作者： Zenglei Hu Ya Huang jiao Hu Xiaoquan Wang Shunlin Hu Xiufan Liu Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China Yangzhou UniversityYangzhou 225009China Animal Infectious Disease Laboratory School of Veterinary MedicineYangzhou UniversityYangzhou 225009China Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses Yangzhou UniversityYangzhou 225009China

H7N9 subtype avian influenza virus poses a great challenge for poultry *** disease virus(NDV)-vectored H7N9 avian influenza vaccines(NDV_(vec)H7N9)are effective in disease control because they are protective and allow mass *** note,these vaccines elicit undetectable H7N9-specific hemagglutination-inhibition(HI)but high IgG antibodies in ***,the molecular basis and protective mechanism underlying this particular antibody immunity remain ***,immunization with an NDV_(vec)H7N9 induced low anti-H7N9 HI and virus neutralization titers but high levels of hemagglutinin(HA)-binding IgG antibodies in *** residues(S150,G151 and S152)in HA of H7N9 virus were identified as the dominant epitopes recognized by the NDV_(vec)H7N9 immune *** transferred NDV_(vec)H7N9 immune serum conferred complete protection against H7N9 virus infection in *** NDV_(vec)H7N9 immune serum can mediate a potent lysis of HA-expressing and H7N9 virus-infected cells and significantly suppress H7N9 virus *** activities of the serum were significantly impaired after heat-inactivation or treatment with complement inhibitor,suggesting the engagement of the complement ***,mutations in the 150-SGS-152 sites in HA resulted in significant reductions in cell lysis and virus neutralization mediated by the NDV_(vec)H7N9 immune serum,indicating the requirement of antibody-antigen binding for complement ***,antibodies induced by the NDV_(vec)H7N9 can activate antibody-dependent complement-mediated lysis of H7N9 virus-infected cells and complement-mediated neutralization of H7N9 *** findings unveiled a novel role of the complement in protection conferred by the NDV_(vec)H7N9,highlighting a potential benefit of engaging the complement system in H7N9 vaccine design.

关键词： H7N9 subtype avian influenza virus NDV vector vaccine antibody immunity complement protection

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Analysis on unit maximum capacity of orthogonal multiple watermarking for multimedia signals in B5G wireless communications

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Digital Communications and Networks 2024年第1期10卷 38-44页

作者： Mianjie Li Senfeng Lai jiao Wang Zhihong Tian Nadra Guizani Xiaojiang Du Chun Shan School of Electronics and Information Guangdong Polytechnic Normal UniversityGuangzhou510665China Cyberspace Institute of Advanced Technology Guangzhou UniversityGuangzhou510006China Schoolof Electrical Engineering and Computer Science Washington State UniversityPullmanWA99164USA Department of Computer and Information Science Temple UniversityPhiladelphiaPA19122USA

Beyond-5G(B5G)aims to meet the growing demands of mobile traffic and expand the communication *** that intelligent applications to B5G wireless communications will involve security issues regarding user data and operational data,this paper analyzes the maximum capacity of the multi-watermarking method for multimedia signal hiding as a means of alleviating the information security problem of *** multiwatermarking process employs spread transform dither *** the watermarking procedure,Gram-Schmidt orthogonalization is used to obtain the multiple spreading ***,multiple watermarks can be simultaneously embedded into the same position of a multimedia ***,the multiple watermarks can be extracted without affecting one another during the extraction *** analyze the effect of the size of the spreading vector on the unit maximum capacity,and consequently derive the theoretical relationship between the size of the spreading vector and the unit maximum capacity.A number of experiments are conducted to determine the optimal parameter values for maximum robustness on the premise of high capacity and good imperceptibility.

关键词： B5G Multimedia information security Spread transform dither modulation Spreading vector measurement Unit maximum capacity

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Runoff change in the Yellow River Basin of China from 1960 to 2020 and its driving factors

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Journal of Arid Land 2024年第2期16卷 168-194页

作者： WANG Baoliang WANG Hongxiang jiao Xuyang HUANG Lintong CHEN Hao GUO Wenxian School of Water Conservancy North China University of Water Resources and Electric PowerZhengzhou 450046China College of Water Resources North China University of Water Resources and Electric PowerZhengzhou 450046China

Analysing runoff changes and how these are affected by climate change and human activities is deemed crucial to elucidate the ecological and hydrological response mechanisms of *** Indicators of Hydrologic Alteration and the Range of Variability Approach(IHA-RVA)method,as well as the ecological indicator method,were employed to quantitatively assess the degree of hydrologic change and ecological response processes in the Yellow River Basin from 1960 to *** Budyko's water heat coupling balance theory,the relative contributions of various driving factors(such as precipitation,potential evapotranspiration,and underlying surface)to runoff changes in the Yellow River Basin were quantitatively *** results show that the annual average runoff and precipitation in the Yellow River Basin had a downwards trend,whereas the potential evapotranspiration exhibited an upwards trend from 1960 to *** approximately 1985,it was reported that the hydrological regime of the main stream underwent an abrupt *** degree of hydrological change was observed to gradually increase from upstream to downstream,with a range of 34.00%-54.00%,all of which are moderate ***,significant differences have been noted among different ecological indicators,with a fluctuation index of 90.00%at the outlet of downstream hydrological stations,reaching a high level of *** the mutation,the biodiversity index of flow in the middle and lower reaches of the Yellow River was generally lower than that in the base *** research results also indicate that the driving factor for runoff changes in the upper reach of the Yellow River Basin is mainly precipitation,with a contribution rate of 39.31%-54.70%.Moreover,the driving factor for runoff changes in the middle and lower reaches is mainly human activities,having a contribution rate of 63.70%-84.37%.These results can serve as a basis to strengthen the protection and restoration efforts in the Yellow River Basin

关键词： Budyko theory hydrological regime attribution analysis ecological responses Yellow River climate change human activity runoff

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New Hybrid CHP System Integrating Solar Energy and Exhaust Heat Thermochemical Synergistic Conversion with Dual-Source Energy Storage

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Journal of Thermal Science 2024年第3期33卷 970-984页

作者： QIN Yuanlong LIU Taixiu LI Peijing ZHAO Kai jiao Fan PEI Gang LIU Qibin Department of Thermal Science and Energy Engineering University of Science and Technology of ChinaHefei230027China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100049China School of Energy Power and Mechanical EngineeringNorth China Electric Power UniversityBeijing102206China

For the efficient use of solar and fuels and to improve the supply-demand matching performance in combined heat and power(CHP)systems,this paper proposes a hybrid solar/methanol energy system integrating solar/exhaust thermochemical and thermal energy *** proposed system includes parabolic trough solar collectors(PTSC),a thermochemical reactor,an internal combustion engine(ICE),and hybrid storage of thermal and chemical energy,which uses solar energy and methanol fuel as input and outputs power and *** methanol thermochemical decomposition reaction,mid-and-low temperature solar heat and exhaust heat are upgraded to chemical energy for efficient power *** thermal energy storage(TES)stores surplus thermal energy,acting as a backup source to produce heat without emitting CO_(2).Due to the energy storage,time-varying solar energy can be used steadily and efficiently;considerable supply-demand mismatches can be avoided,and the operational flexibility is *** the design condition,the overall energy efficiency,exergy efficiency,and net solar-to-electric efficiency achieve 72.09%,37.65%,and 24.63%,*** fuel saving rate(FSR)and the CO_(2) emission reduction(ER_(CO_(2)))achieve 32.97%and 25.33%,*** research findings provide a promising approach for the efficient and flexible use of solar energy and fuels for combined heat and power.

关键词： hybrid energy system solar thermochemical exhaust heat energy storage operational flexibility

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Radial growth in Qinghai spruce is most sensitive to severe drought in the Qilian Mountains of Northwest China

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Journal of Forestry Research 2024年第3期35卷 73-86页

作者： Xuge Wang Liang jiao Ruhong Xue Peng Zhang Dashi Du Mengyuan Wei Qian Li College of Geography and Environmental Science Northwest Normal UniversityNo.967Anning East RoadLanzhou 730070People's Republic of China Key Laboratory of Resource Environment and Sustainable Development of Oasis Northwest Normal UniversityLanzhou 730070Gansu ProvincePeople's Republicof China

Global warming and frequent extreme drought events lead to tree death and extensive forest decline,but the underlying mechanism is not *** drought years,cambial development is more sensitive to climate change,but in different phenological stages,the response rela-tionship is ***,the dynamic relationship between tree radial growth and climatic/environmental fac-tors needs to be *** thus continuously monitored radial growth of Qinghai spruce(Picea crassifolia Kom.)and environmental factors from January 2021 to November 2022 using point dendrometers and portable meteorological weather stations in the central area of the Qilian *** relationship and stability between the radial growth of Qinghai spruce and environmental factors were compared for different levels of drought in 2021 and *** year 2022 had higher temperatures and less precipitation and was drier than *** with 2021,the growing period in 2022 for Qinghai spruce was 10 days shorter,maximum growth rate(Grmax)was 4.5μm·d^(-1) slower,and the initiation of growth was 6 days *** of Qinghai spruce was always restricted by drought,and the stem radial increment(SRI)was more sensitive to precipitation and air relative *** changes in cumulative radial growth were divided into four phenological stages according to the time of growth onset,cessation,and maximum growth rate(Grmax)of Qinghai *** responses of SRI to climate change were stronger in Stage 3 and Stage 4 of 2021 and stronger in Stage 1(initiation growth stage)and Stage 3 of *** results provide important information on the growth of the trees in response to drought and for specific managing forests as the climate warms.

关键词： Picea crassifolia Radial growth dynamics Severe drought Response stability Point dendrometer

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Design of an aircraft autonomous traction taxiing system based on hydraulic secondary control

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Chinese Journal of Aeronautics 2024年第6期37卷 348-359页

作者： Xiaochao LIU Zhongyi QIU Hao ZHANG Pengyuan QI Zhenyu WANG Yaoxing SHANG Zongxia jiao Research Institute for Frontier Science Beihang UniversityBeijing 100083China School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100083China Ningbo Institute of Technology Beihang UniversityNingbo 315800China Tianmushan Laboratory Xixi Octagon CityYuhang DistrictHangzhou 310023China Science and Technology on Aircraft Control Laboratory Beihang UniversityBeijing 100083China Beijing Tianma Intelligent Control Technology Co. Ltd.Beijing 101399China China Coal Research Institute Beijing 100013China

At present,aircraft taxiing at ground airports needs to be provided with a thrust by the main *** taxiing process is inefficient,has high fuel consumption and serious pollution,and is prone to safety *** this paper,a new configuration of aircraft autonomous traction taxiing system is proposed based on the principle of hydraulic secondary control,in which a hydraulic motor drive device is installed at the front wheels of the aircraft to drive the wheels to rotate forward or *** on this,autonomous taxiing can be realized without relying on the main engines,thus greatly improving airport operation ***,this paper analyzes the influencing factors of the autonomous traction taxiing process,and investigates the parameter matching design of the new configuration ***,this paper develops the ground principle prototype,designs the aircraft longitudinal bonding force observer and the aircraft wheel disturbance moment observer,and proposes the speed control method of the aircraft front wheel autonomous traction taxiing by considering the ground bonding force saturation ***,the ground taxiing test is conducted,and the results show that the new configuration proposed in this paper presents a new solution for aircraft autonomous traction taxiing.

关键词： Autonomous traction taxi-ing Hydraulic secondary control Hydraulic motors Saturation characteristics Disturbance observation Speed control

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