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Ginkgo biloba leaf extract effects on inducible nitric oxide synthase, Bcl-2, and Bax expression in rat models of spinal cord injury

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Neural Regeneration Research 2008年第8期3卷 875-880页

作者： Jiejun jiao Bin du Seventh Area Department of Orthopaedics Yixing People＇s Hospital Yixing 214200 Jiangsu Province China

BACKGROUND：Ginkgo biloba leaf extract exhibits neuroprotective effects in spinal cord injury. However, the mechanisms of action remain unclear. OBJECTIVE： To investigate inducible nitric oxide synthase （iNOS） and Bcl-2/Bax expression in the injured spinal cord, and to explore the neuroprotective mechanisms of ginkgo biloba leaf extract in rats with spinal cord injury. DESIGN, TIME AND SETTING： The randomized, controlled, cell molecular biology experiment was performed at Soochow University, China from March 2007 to March 2008. MATERIALS： A total of 120 healthy, adult Sprague Dawley rats were selected for this study. Rat models of moderate acute thoracic （T9） spinal cord injury were established using the modified Allen method. Shuxuening injection was obtained from Zhenbaodao Pharmaceutical Co., Ltd., China. Methylprednisolone was purchased from North China Pharmaceutical Co., Ltd. METHODS： All rats were equally and randomly divided into four groups. Only the spinal cord was exposed in the sham operation group rats. In the trauma group, rats were not treated with drugs following spinal cord injury. Rats in the hormone group were intraperitoneally injected with 30 mg/kg methylprednisolone following spinal cord injury. Rats in the ginkgo biloba leaf extract group were intraperitoneally infused with a 1.0 mL/kg Shuxuening injection per day. MAIN OUTCOME MEASURES： At 1 hour, as well as 1, 3, 5, 7, and 14 days after spinal cord injury, iNOS- and Bcl-2/Bax-positive cells were quantified with immunohistochemistry. Pathological changes were detected using hematoxylineosin staining under an optical microscope. RESULTS： Spinal cord injury in the ginkgo biloba leaf extract and hormone groups was milder compared with the trauma group. Demyelination was significantly ameliorated and the necrotic cavity was obviously reduced in the injured spinal cord of rats in the ginkgo biloba leaf extract and hormone groups at each time point. iNOS expression was increased in the injured spina

关键词： apoptosis Bcl-2/Bax ginkgo biloba leaf extract inducible nitric oxide synthase methylprednisolone neuroprotection spinal cord injury

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Construction and Count of 1-Resilient Rotation Symmetric Boolean Functions on 4p Variables

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Chinese Journal of Electronics 2017年第6期26卷 1276-1283页

作者： PANG Shanqi XU Wenju du jiao WANG Ying College of Mathematics and Information Science Henan Normal University

This paper studies the properties of orbit matrix and gives a formula to compute the number of these orbit matrices on 4p variables, where p is an odd prime. It has been demonstrated that the construction of 1-resilient Rotation symmetric Boolean functions(RSBFs) on 4p variables is equivalent to solving an equation system. By the proposed method, all 1-resilient RSBFs on 12 variables can be constructed. We present a counting formula for the total number of all 1-resilient RSBFs on 4p variables. As application of our method, some 1-resilient RSBFs on 12 variables are presented.

关键词： Cryptography Rotation symmetric Boolean functions Orbit matrix Resilient functions

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Fabrication of anti-fouling polyamide nanofiltration membrane by incorporating streptomycin as a novel co-monomer

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Chinese Journal of Chemical Engineering 2022年第10期50卷 185-196页

作者： Shujie Guo jiao du Fangzheng Yan Zhi Wang Jixiao Wang Chemical Engineering Research Center School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300350China Tianjin Key Laboratory of Membrane Science and Desalination Technology State Key Laboratory of Chemical EngineeringCollaborative Innovation Center of Chemical Science and EngineeringTianjin UniversityTianjin 300350China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300350China

Polyamide(PA)thin-film composite(TFC)na nofiltration(NF)membrane has extremely broad application prospects in separation of monovalent/diva lent inorganic salts mixed solutio ***,membrane fouling is the main obstacle to the application of PA,TFC and NF ***(SM)is a hydrophilic antibiotic containing a large number of hydroxyl and amino *** this work,the NF membrane was prepared via interfacial polymerization(IP)between trimesoyl chloride(TMC)in the organic phase and SM/piperazine(PIP)mixture in the aqueous *** NF membrane structure and performance were characterized in *** results showed that SM successfully participated in the *** negative charge and hydrophilicity of membrane surface were *** prepared membrane exhibited good anti-adhesion and anti-bacterial performance,Additionally,when the SM concentration was 2%,the prepared membrane exhibited the optimal *** water permeance was 89.4L·m^(-2)·h^(-1)·MPa^(-1).The rejection of NaCl and Na_(2)SO_(4) were 17,17%and 97.84%,*** NaCl/Na_(3)SO_(4) separation factor of the SM2-PIP/TMC membrane in 1000 mg·L^(-1) NaCl and 1000 mg·L^(-1)Na_(2)SO_(4) mixed solution was 40,which was 3.3 times that of PIP/TMC *** indicated that SM2-PIP/TMC demonstrated excellent monovalent/divalent salts separation *** work provided an easy and effective approach to preparing anti-fouling NF membrane while possessing superior monovalent/divalent salts separation performance.

关键词： Streptomycin Polyamide Nanofiltration membrane Anti-adhesion Anti-bacterial

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The Existence of a Class of Balanced Multi-output Rotation Symmetric Boolean Functions

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Chinese Journal of Electronics 2018年第5期27卷 995-1001页

作者： du jiao FU Shaojing QU Longjiang LI Chao PANG Shanqi College of Mathematics and Information Science Henan Normal University Henan Engineering Laboratory for Big Data Statistical Analysis and Optimal Control Henan Normal University College of Computer Science National University of Defense Technology College of Liberal Arts and Science National University of Defense Technology

A new characterization of balanced rotation symmetric（n, m）-functions is presented. Based on the characterization, the nonexistence of balanced rotation symmetric（p;, m）-functions is determined, where p is an odd prime and m ≥ 2. And there exist balanced rotation symmetric（2;, m）-functions for 2 ≤ m ≤ 2;-r. With the help of these results, we also prove that there exist rotation symmetric resilient（2;, m）-functions for 2 ≤ m ≤ 2;-r-1.

关键词： Cryptography Rotation symmetric Orbit matrix Correlation immune Resilient functions

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Construction and Count of 1-Resilient Rotation Symmetric Boolean Functions on pr Variables

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Chinese Journal of Electronics 2014年第4期23卷 816-820页

作者： du jiao PANG Shanqi WEN Qiaoyan LIAO Xin College of Mathematics and Information Science Henan Normal University State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications College of Information Science and Engineering Hunan University

Construction and count of 1-resilient Rotation symmetric Boolean functions(RSBFs) on p r variables are demonstrated. It is proved that constructions of1-resilient RSBFs on p r variables are equivalent to solving an equation system. An accurate enumeration formula of all 1-resilient RSBFs on p r variables is also proposed. Some examples are given, and the exact numbers of 1-resilient RSBFs on 8 and 9 variables are obtained respectively.

关键词： Cryptography Rotation symmetric Support table Correlation-immune Resilient functions

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Construction of a Class of Quantum Boolean Functions Based on the Hadamard Matrix

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Acta Mathematicae Applicatae Sinica 2015年第4期31卷 1013-1020页

作者： jiao du Shan-qi PANG Qiao-yan WEN Jie ZHANG College of Mathematics and Information Science Henan Normal University Henan Engineering Laboratory for Big Data Statistical Analysis and Optimal Control Henan Normal University State Key Laboratory of Networking and Switching Technology Beijing University of Posts and Telecommunications School of Science Beijing University of Posts and Telecommunications

In this study, a new methodology based on the Hadamard matrix is proposed to construct quantum Boolean functions f such that f ： I2n --2P2n, where I2n is an identity matrix of order 2n and P2n is a projective matrix ... 详细信息

关键词： quantum information matrix image quantum boolean function projective matrix

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New constructions of q-variable 1-resilient rotation symmetric functions over Fp

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Science China(Information Sciences) 2016年第7期59卷 240-242页

作者： jiao du Shaojing FU Longjiang QU Chao LI Shanqi PANG College of Science National University of Defense Technology School of Mathematics and Information Science Henan Normal University Henan Engineering Laboratory for Big Data Statistical Analysis and Optimal Control Henan Normal University College of Computer Science National University of Defense Technology

Dear editor,Motivated by Refs.[1–10],we devote to constructing a class of q-variable 1-resilient rotation symmetric functions（RSFs）over the finite field F;={0,1,...,p-1}in this *** this letter,let p and q be differ... 详细信息

关键词： over New constructions of q-variable 1-resilient rotation symmetric functions over F_p

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Correlation of the Appearances of DSA with VEGF Expression and Its Clinical Significance in Patients with Primary Hepatocellular Carcinoma

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The Chinese-German Journal of Clinical Oncology 2006年第4期5卷 257-260页

作者： CHEN Fangman jiao Xudong du Fang Department of Radiology Yijishan Hospital of Wannan Medical College Wuhu 241001 China

Objective： To investigate the relationship between the appearances of digital subtraction angiography （DSA） and the serum level of vascular endothelial growth factor （VEGF） in patients with primary hepatocellular carcinoma （HCC）. Methods： 24 HCC patients, 30 times DSA were examined, serum VEGF level was measured with the quantitative enzyme linked immunosorbent assay （ELISA） in patients and healthy control subjects in this study. Results： Among DSA for 24 patients with HCC, 18 of 24 cases showed hepatic artery blood supply of tumor. Four of 24 cases showed portal vein blood supply of tumor, 1 of 24 cases showed superior mesenteric artery blood supply of tumor and artery-venous shunt formation, and there was no blood supply to tumor in one case. Serum VEGF level in HCC[（χ＋s）194.5±14.2] ng/L was significant elevated to those in patients comparing with those of the normal controls （132.4±47.9） ng/L and marked differences （P〈0.01）. Conclusion： during the cases for plenty blood supply or arteryvenous shunt formation in patients with HCC, serum VEGF level markedly elevated in the patients of HCC. VEGF expression was significantly related to intrahepatic dissemination, recurrence and metastasis in patients with HCC.

关键词： hepatocellular carcinoma (HCC) digital subtraction angiography (DSA) Vascular Endothelial Growth Factor (VEGF)

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Selective extraction of dimethoate from cucumber samples by use of molecularly imprinted microspheres

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Journal of Pharmaceutical Analysis 2015年第3期5卷 200-206页

作者： jiao-jiao du Rui-Xia Gao Hu Yu Xiao-Jing Li Hui Mu Department of Chemistry School of ScienceXi'an Jiaotong University

Molecularly imprinted polymers for dimethoate recognition were synthesized by the precipitation polymerization technique using methyl methacrylate （MMA） as the functional monomer and ethylene glycol dimethacrylate （EGDMA） as the cross-linker. The morphology, adsorption and recognition properties were investigated by scanning electron microscopy （SEM）, static adsorption test, and competitive adsorption test. To obtain the best selectivity and binding performance, the synthesis and adsorption conditions of MIPs were optimized through single factor experiments. Under the optimized conditions, the resultant polymers exhibited uniform size, satisfactory binding capacity and significant selectivity. Furthermore, the imprinted polymers were successfully applied as a specific solid-phase extractants combined with high performance liquid chromatography （HPLC） for determination of dimethoate residues in the cucumber samples. The average recoveries of three spiked samples ranged from 78.5% to 87.9% with the relative standard deviations （RSDs） less than 4.4% and the limit of detection （LOD） obtained for dimethoate as low as 2.3 μg/mL.

关键词： Mol^alarly imprintedpolymer ,Precipitation polymeriza-tion Dimethoate Cucumber HPLC

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Citrinal A,a novel tricyclic derivative of citrinin,from an algicolous fungus Penicillium sp.i-1-1

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Chinese Chemical Letters 2009年第8期20卷 917-920页

作者： Tian jiao Zhu Lin du Peng Fei Hao Zhen Jian Lin Qian Qun Gu Key Laboratory of Marine Drugs Chinese Ministry of Education School of Medicine and Pharmacy Ocean University of China Qingdao 266003 PR China

Citrinal A （1）, a novel tricyclic compound with a rare tetrahydro-2H-benzofuro[7-b] [ 1,4]dioxin-9（3H）-one skeleton, along with two known related compounds, citrinin （2） and 2,3,4-trimethyl-5,7-dihydroxy-2,3-dihydrobenzofuran （3） were isolated from an algicolous fungus Penicillium sp. i-1-1. The structure and stereochemistry of 1 were determined by comprehensive spectral and biogenic analysis. Its cytotoxic effects on the A-549 and HL-60 cell lines were evaluated. ？2009 Qian Qun Gu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Citrinal Algicolous fungus Penicillium

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