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A multichannel thermal bubble-actuated impedance flow cytometer with on-chip TIA based on CMOS-MEMS

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Journal of Semiconductors 2024年第5期45卷 41-49页

作者： Shengxun cai jianqing Nie Kun Wang Yimin Guan Demeng Liu School of Microelectronics Shanghai UniversityShanghai 201800China Shanghai AURE Technology Limited Company Shanghai 201800China

Electrochemical impedance spectroscopy(EIS)flow cytometry offers the advantages of speed,affordability,and portability in cell analysis and cytometry ***,the integration challenges of microfluidic and EIS read-out circuits hinder the downsizing of cytometry *** address this,we developed a thermal-bubble-driven impedance flow cytometric application-specific integrated circuit(ASIC).The thermal-bubble micropump avoids external piping and equipment,enabling high-throughput *** a total of 36 cell counting channels,each measuring 884×220μm^(2),the chip significantly enhances the throughput of flow *** cell counting channel incorporates a differential trans-impedance amplifier(TIA)to amplify weak biosensing *** eliminating the parasitic parameters created at the complementary metal-oxidesemiconductor transistor(CMOS)-micro-electromechanical systems(MEMS)interface,the counting accuracy can be *** on-chip TIA can adjust feedback resistance from 5 to 60 kΩto accommodate solutions with different *** chip effectively classifies particles of varying sizes,demonstrated by the average peak voltages of 0.0529 and 0.4510 mV for 7 and 14μm polystyrene beads,***,the counting accuracies of the chip for polystyrene beads and MSTO-211H cells are both greater than 97.6%.The chip exhibits potential for impedance flow cytometer at low cost,high-throughput,and miniaturization for the application of point-of-care diagnostics.

关键词： EIS flow cytometry CMOS-MEMS thermal bubble lab-on-chip

Application of wavelet support vector regression on SAR data de-noising

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Journal of Systems Engineering and Electronics 2011年第4期22卷 579-586页

作者： Yi Lin Shaoming Zhang jianqing cai Nico Sneeuw Research Center of Remote Sensing and Spatial Technology Tongji University Shanghai 200092 P. R. China Institute of Geodesy University of Stuttgart D-70174 Stuttgart Germany

A new filtering method for SAR data de-noising using wavelet support vector regression （WSVR） is developed. On the basis of the grey scale distribution character of SAR imagery, the logarithmic SAR image as a noise polluted signal is taken and the noise model assumption in logarithmic domain with Gaussian noise and impact noise is proposed. Based on the better per- formance of support vector regression （SVR） for complex signal approximation and the wavelet for signal detail expression, the wavelet kernel function is chosen as support vector kernel func- tion. Then the logarithmic SAR image is regressed with WSVR. Furthermore the regression distance is used as a judgment index of the noise type. According to the judgment of noise type every pixel can be adaptively de-noised with different filters. Through an approximation experiment for a one-dimensional complex signal, the feasibility of SAR data regression based on WSVR is con- firmed. Afterward the SAR image is treated as a two-dimensional continuous signal and filtered by an SVR with wavelet kernel function. The results show that the method proposed here reduces the radar speckle noise effectively while maintaining edge features and details well.

关键词： synthetic aperture radar (SAR) support vector regres-sion (SVR) kernel function wavelet analysis function approximation.

Numerical Study on the Mixed Model in the GOCE Polar Gap Problem

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Geo-Spatial Information Science 2011年第3期14卷 216-222页

作者： ZOU Xiancai cai jianqing Nico Sneeuw LI Jiancheng Institute of Geodesy University of Stuttgart Geschwister-Scholl-Str. 24D D-70174 Stuttgart Germany School of Geodesy and Geomatics Wuhan University 129 Luoyu Road Wuhan 430079 China

Gravity gradients acquired by the Gravity field and steady-state Ocean Circulation Explorer(GOCE) do not cover the entire earth because of its sun-synchronous orbit leaving data gaps with a radius of about 6.5° in the polar *** studies showed that the loss of data in the polar regions deteriorates the accuracy of the low order(or near zonal) coefficients of the earth gravity model,which is the so-called polar gap problem in *** order to find a stable solution for the earth gravity model from the GOCE gravity gradients,three models,*** Gauss-Markov model,light constraint model and the mixed model,are compared and evaluated numerically with the gravity gradient simulated with the *** comparison shows that the Best Linear Uniformly Unbiased Estimation(BLUUE) estimator of the mixed model can solve the polar gap problem as effectively as the light constraint model;furthermore,the mixed model is more rigorous in dealing with the supplementary information and leads to a better accuracy in determining the global geoid.

关键词：地球重力模型卫星重力 GOCE 混合模型极的差距问题

Untrained neural network for linear tomographic absorption spectroscopy

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Science China Technological Sciences 2024年第9期67卷 2787-2796页

作者： Chen JingRuo Xu ShiJie Liu HeCong Huang jianqing Liu YingZheng cai WeiWei Key Lab of Education Ministry for Power Machinery and Engineering School of Mechanical EngineeringShanghai Jiao Tong University EMPI Institute for Energy and Materials Processes Reactive FluidsUniversity of Duisburg-Essen Department of Electrical and Electronic Engineering The University of Hong Kong

Linear tomographic absorption spectroscopy(LTAS) is a non-destructive diagnostic technique widely employed for gas *** inverse problem of LTAS represents a classic example of an ill-posed problem. Linear iterative algorithms are commonly employed to address such problems, yielding generally poor reconstruction results due to the incapability to incorporate suitable prior conditions within the reconstruction process. Data-driven deep neural networks(DNN) have shown the potential to yield superior reconstruction results; however, they demand a substantial amount of measurement data that is challenging to *** surmount this limitation, we proposed an untrained neural network(UNN) to tackle the inverse problem of LTAS. In conjunction with an early-stopping method based on running variance, UNN achieves improved reconstruction accuracy without supplementary training data. Numerical studies are conducted to explore the optimal network architecture of UNN and to assess the reliability of the early-stopping method. A comparison between UNN and superiorized ART(SUP-ART) substantiates the exceptional performance of UNN.

关键词： absorption spectroscopy linear tomography untrained neural networks combustion diagnostics

Shor's algorithm does not factor large integers in the presence of noise

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Science China(Information Sciences) 2024年第7期67卷 305-320页

作者： Jin-Yi cai College of Letters and Science University of Wisconsin

We consider Shor's quantum factoring algorithm in the setting of noisy quantum gates. Under a generic model of random noise for(controlled) rotation gates, we prove that the algorithm does not factor integers of the form pq when the noise exceeds a vanishingly small level in terms of n—the number of bits of the integer to be factored, where p and q are from a well-defined set of primes of positive density. We further prove that with probability 1-o(1) over random prime pairs(p, q), Shor's factoring algorithm does not factor numbers of the form pq, with the same level of random noise present.

关键词： random noise Shor's algorithm rotation gates quantum computing prime factorization

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Whittle’s Index Based Sensor Scheduling for Multiprocess Systems Under DoS Attacks

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Journal of Systems Science & Complexity 2024年第1期37卷 329-350页

作者： cai Zai DING Kemi Shenzhen Key Laboratory of Control Theory and Intelligent Systems Southern University of Science and TechnologyShenzhen 518055China.

In this paper,the authors consider how to design defensive countermeasures against DoS attacks for remote state estimation of multiprocess *** each system,a sensor will measure its state and transmits the data packets through an unreliable channel which is vulnerable to be jammed by an *** limited communication bandwidth,only a subset of sensors are allowed for data transmission,and how to select the optimal one to maximize the accuracy of remote state estimation is the focus of the proposed *** authors first formulate this problem as a Markov decision process and investigate the existence of optimal ***,the authors demonstrate the piecewise monotonicity structure of optimal *** the difficulty of obtaining an optimal policy of large-scale problems,the authors develop a suboptimal heuristic policy based on the aforementioned policy structure and Whittle’s ***,a closed form of the indices is derived in order to reduce implementation complexity of proposed scheduling policy and numerical examples are provided to illustrate the proposed developed results.

关键词： DoS attacks Kalman filter remote state estimation Whittle’s index.

Polarized imaging dynamic light scattering for simultaneous measurement of nanoparticle size and morphology

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Particuology 2024年第2期85卷 213-223页

作者： Bingyao Wang Tianyi cai Xiaoshu cai Wu Zhou Zeqi Liu Schoolof Energy and Power Engineering University of Shanghai for Science and TechnologyShanghai200093China Shanghai Key Laboratory of Multiphase Flow and Heat Transfer in Power Engineering Shanghai200093China Jiaxing MeaParTech Instrument Technology Co. LtdZhejiang314000China

The performance of nanoparticles is often affected by particle size and ***,electron microscopy or atomic force microscopy is typically utilized to determine the size and morphology of ***,there are issues such as difficult sample preparation,long processing times,and challenges in quantitative ***,it is of great significance to develop a fast,accu-rate,and statistical method to measure the size and morphology of *** this study,a new method,called polarized imaging dynamic light scattering(PIDLS),is *** nanoparticles are irradiated with a vertical linearly polarized laser beam,and a polarization camera collected the dynamic light scattering images of particles at four different polarization directions(0°,45°,90°,and 135°)at a scattering angle of 90°.The average particle size and distribution are obtained using the imaging dy-namic light scattering method at 0°polarization direction,and the morphology of the particles is ob-tained based on the depolarization patterns of the scattered *** optical sphericityΦis defined based on the degree of linear polarization(DoLP).It is also implemented for the quantitative evaluation of the sphericity of the nanoparticles,including spherical,octahedral,nanoplate,nanorod,and linear *** with the Poincarésphere parameterψ,the morphology of the nanoparticles can be roughly *** addition,PIDLS enables the measurement of particle size and morphology distributions simultaneously for evaluating the uniformity of *** effectiveness of PIDLS is verified by the measurement of five kinds of industrial titanium dioxide as well.

关键词： Imaging dynamic light scattering Polarized light scattering Non-spherical nanoparticles Morphology Online measurement

An ultra-porous g-C_(3)N_(4) micro-tube coupled with MXene(Ti_(3)C_(2)TX)nanosheets for efficient degradation of organics under natural sunlight

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Journal of Environmental Sciences 2024年第3期137卷 258-270页

作者： Zongyang Ya Qiyou Wang Jingjin cai Peng Wang Xinyu Jiang Zhiyin cai Shanglin Xiang Tingwei Wang Dongyu cai College of Materials Science&Engineering Nanjing Tech University30 South PuZhu RoadNanjing 211816China Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)Nanjing Tech University30 South PuZhu RoadNanjing 211816China

It remains as a challenge for realizing efficient photo-responsive catalysts towards largescale degradation of organic pollutants under natural *** work reports a new pore engineering strategy for creating ultra-porous g-C_(3)N_(4) micro-tubes with an unprecedentedly high specific surface area of 152.96 m^(2)/*** is mainly associated with releasing internal vapor pressure in the autoclave where the hydrothermal treatment of the urea/melamine mixture is *** by microscopic observation,porosity measurement and spectroscopic characterization,it is found that releasing the pressure at halfway of hydrothermal process is vital for forming exfoliated rod-like precursors and the de-aggregation of these rods presents substantial benefits on the production of mesopores on g-C_(3)N_(4) microtubes during the calcination of *** offers a large number of reactive sites required by photocatalytic *** these micro-tubes with Ti_(3)C_(2)T_(X) nanosheets via electrostatic interaction yields a 1D/2D heterojunction with a close interfacial *** addition of metallically conductive Ti_(3)C_(2)T_(X) nanosheets accelerates the separation between electrons and holes,and also enhances the light *** these merits of structural design lead to forming a group of highly efficient catalysts demonstrating an excellent photocatalytic degradation rate of k=0.0560 min^(-1)for RhB dyes under 100 mW/cm~2 visible light radiation that micks sunlight *** laboratory valuation is further supported by an outdoor test that shows a fast degradation rate of 0.0744 min^(-1)under natural sunlight.

关键词： Carbon nitride MXene Heterojunction Photocatalysis

Microbial carbon pump shapes chemical signatures of refractory dissolved organic carbon in ocean water column

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Science China Earth Sciences 2024年第7期67卷 2408-2410页

作者： Ruanhong cai Nianzhi JIAO Fujian Key Laboratory of Marine Carbon Sequestration Xiamen UniversityXiamen 361102China Department of Ocean Science The Hong Kong Universityof Science and TechnologyHong Kong SAR 999077China Carbon Neutral Innovation Research Center Xiamen UniversityXiamen 361102China

The global ocean sequesters a great amount of dissolved organic carbon(DOC),which is mainly originated from indigenous microbial activities(such as photosynthesis and chemoautotrophy)in the water column,as well as various exogenous sources such as riverine input,sediment mobilization,aerosol dissolution,hydrothermal vent effusion,and others(cai and Jiao,2023).

关键词： ocean originated aerosol

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