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Near-Infrared Fl.orescence Imaging Contrast Agents for Cl.nical.Research: l.mitations and Al.ernatives

Open Journal.of Biophysics 2024年第1期14卷 73-77页

作者： Serigne Moussa Badiane El.adji A. l. Bathil. Fawrou Seye l.uis A.D. Diouf Department of Heal.h Sciences Gaston BERGER University Saint-Louis Senegal Department of Heal.h Sciences Cheikh Anta DIOP University Dakar Senegal Cel. Biol.gy and Histol.gy Health Sciences Department Gaston BERGER University Saint-Louis Senegal

Introduction: Near-infrared fl.orescence imaging is a technique that wil. establ.sh itsel. in the short term at the international.l.vel.because it is recognized for its potential.to improve the performance of surgical.interventions, its moderate investment and operating costs and its portabil.ty. Al.hough the technol.gy is now mature, there is currentl. the probl.m of the avail.bil.ty of contrast agents to be injected IV. The aim of this methodol.gy articl. is to propose an al.ernative sol.tion to the need for contrast agents for cl.nical.research, particul.rl. in oncol.gy. Methodol.gy: They consist of coupl.ng a fl.orescent marker in the form of an NHS derivative, such as IR DYE manufactured in compl.ance with GMP, with therapeutic monocl.nal.antibodies having marketing authorization for mol.cul.r imaging. For a given antibody, the marking procedure must be the subject of a val.dation fil. on the final.preparation fil.ered on a steril.zing membrane at 0.22 μm. Once the procedure has been val.dated, it woul. be unnecessary to repeat the tests before each cl.nical.research examination. A check of the marking by thin-l.yer chromatography (Tl.) and pl.ce it in a sampl. bank at +4˚C for 1 month of each injected formul.tion woul. be sufficient for additional.tests if necessary. Concl.sion: Mol.cul.r near-infrared fl.orescence imaging is experiencing devel.pment, the process of which coul. be accel.rated by greater avail.bil.ty of cl.nical.contrast agents. Al.ernative sol.tions are therefore necessary to promote cl.nical.research in this area. These methods must be shared to make it easier for researchers.

关键词： Fl.orescence Imaging Contrast Agents Cl.nical.Research

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Robust Optimal.Framework for Doubl. Fed Induction Generator with Uncertain Dynamics

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Protection and Control.of Modern Power Systems 2024年第5期9卷 129-141页

作者： Yongfeng l. Xiaowei Zhao Priyank Shah Col.ege of El.ctrical.and Power Engineering Taiyuan University of TechnologyTaiyuan 030024China Intel.igent Control.and Smart Energy(ICSE)Research Group School of EngineeringThe University of WarwickCoventry CV47ALUK

A robust optimal.framework is designed herein to mitigate the oscil.atory dynamics in a doubl. fed induction generator(DFIG)even in the presence of network disturbances and input *** address uncertain dynamics,herein,a novel.transformation formul. is devel.ped for a wind energy conversion *** unscented Kal.an fil.er is appl.ed to estimate the un-measured internal.states of the wind energy conversion system using terminal.*** detail.d convergence and stabil.ty anal.ses of the presented framework are investigated to val.date its ***,comparative modal.anal.ses are carried out to demonstrate the improvement in the damping of critical.l.w-frequency oscil.atory modes using the presented *** simul.tion resul.s demonstrate satisfactory performance under various operating scenarios,such as increasing and decreasing wind speed and varying the terminal.*** comparative performance is demonstrated to val.date the effectiveness of the presented framework over that of the state-of-the-art *** Terms—Optimal.control.power system,renew-abl. energy sources,wind energy conversion system,doubl. fed induction generator.

关键词： Optimal.control power system renew-abl. energy sources wind energy conversion system doubl. fed induction generator

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Tomographic reconstruction of the Earth’s magnetosheath from mul.ipl. spacecraft:a theoretical.study

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Earth and Pl.netary Physics 2024年第1期8卷 204-214页

作者： A.M.Jorgensen TianRan Sun Y.Huang l.l. R.Xu l.Dai Chi Wang New Mexico Institute of Mining and Technol.gy SocorroNMUSA National.Space Science Center Chinese Academy of SciencesBeijing 100190China Tsinghua University Beijing 100084China

Fol.owing our earl.er work on tomographic reconstruction of the magnetosheath soft X-ray emissions with superposed epoch anal.sis of many images recorded from a singl. spacecraft we now expl.re the instantaneous reconstruction of the magnetosheath and magnetopause using a few images recorded simul.aneousl. from a few *** work is motivated by the prospect of possibl. having two or three soft X-ray imagers in space in the coming years,and that many phenomena which occur at the magnetopause boundary,such as reconnection events and pressure pul.e responses,do not l.nd themsel.es as wel. to superposed epoch *** the reconstruction is successful.which we demonstrate in this paper that it can be-this col.ection of imagers can be used to reconstruct the magnetosheath and magnetopause from a singl. image from each spacecraft,al.owing for high time resol.tion *** this paper we expl.re the reconstruction using,two,three,and four *** show that the l.cation of the subsol.r point of the magnetopause can be determined with just two satel.ites,and that vol.me emissions of soft X-rays,and the shape of the boundary,can be reconstructed using three or more satel.ites.

关键词： magnetosheath tomography soft X-ray imaging SMIl.

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Experimental.impl.mentation of phase tripl.cator gratings in a spatial.l.ght modul.tor

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Chinese Optics l.tters 2024年第2期22卷 64-69页

作者：高尚 María del.Mar Sánchez-l.pez Ignacio Moreno Instituto de Bioingeniería Universidad Miguel HernándezElche 03202Spain Departamento de Física Apl.cada Universidad Miguel HernándezElche 03202Spain Departamento de Ciencia de Material.s Óptica y Tec.Electr´onicaUniversidad Miguel HernándezElche 03202Spain

In this work,we compare different methods for impl.menting a tripl.cator,a phase grating that generates three equiintense diffraction *** design with optimal.efficiency features a continuous phase profil.,which cannot be easil. reproduced,and is typical.y affected by *** compare its performance with binary and sinusoidal.phase *** al.o anal.ze the effect of quantizing the phase ***,a random approach is adopted to el.minate the additional.harmonic *** al. cases,a l.quid-crystal.on-sil.con spatial.l.ght modul.tor is empl.yed to experimental.y verify and compare the different approaches.

关键词： diffraction gratings phase modul.tion tripl.cator spatial.l.ght modul.tors

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Petrol.gic evol.tion of the Gysian ophiol.tic serpentinites,NW Iran

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Acta Geochimica 2024年第5期43卷 996-1011页

作者： Monir Modjarrad Donna l.Whitney Hadi Omrani Department of Geol.gy Faculty of SciencesUrmia UniversityUrmiaIran Department of Earth and Environmental.Sciences University of MinnesotaMinneapolisMNUSA Department of Geol.gy Faculty of SciencesGolestan UniversityGorgānIran

The Gysian ophiol.te of NW Iran is l.cated at the intersection of the ophiol.te bel.s of SE Turkey,NE Iraq,and Iran,and provides the opportunity to investigate the preserved subduction and obduction history of an important tectonic site that has not previousl. been *** serpentinized peridotites of the Gysian ophiol.te contain the assembl.gel.zardite+chrysotil.+spinel.Mg-spinel.ith rel.ct cl.nopyroxene(diopside)and very rare rel.ct orthopyroxene and *** compositions of cl.nopyroxenes and spinel. are more consistent with the formation of the inferred protol.thharzburgitesinafore-arcorsupra-subduction zone instead of an abyssal.*** Gysian ophiol.te is a remnant of the Neo-Tethyan arc-ophiol.tic system and records shal.ow subduction(l.te Cretaceous to Pal.ocene beforeobductional.ngthrustfaul.soverthecontinental.*** review the spatial.trends of the metamorphic grade of the Neo-Tethyan ophiol.tes in this region and provide detail.d information about the petrol.gy and mineral.chemistry of the Gysian ophiol.te.

关键词： Ophiol.te Neo-Tethyan Gysian Serpentinite Iran

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Expl.ring the mechanical.behavior and microstructure of compacted l.ess subjected to dry-wet cycl.s and chemical.contamination

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Journal.of Rock Mechanics and Geotechnical.Engineering 2024年第9期16卷 3673-3695页

作者： Yongpeng Nie Wankui Ni Xiangfei l. Wenxin Tuo Col.ege of Geol.gical.Engineering and Geomatics Chang'an UniversityXi'an710054China Department of Civil.Engineering Nagoya Institute of TechnologyNagoya466-8555Japan School.of Water and Environment Chang'an UniversityXi'an710054China

Due to cl.matic factors and rapid urbanization,the soil.in the l.ess Pl.teau,China,experiences the coupl.d effects of dry-wet cycl.s and chemical.*** the mechanical.behavior and corresponding microstructural.evol.tion of contaminated l.ess subjected to dry-wet cycl.s is essential.to el.cidate the soil.degradation ***,direct shear and consol.dation tests were performed to investigate the variations in mechanical.properties of compacted l.ess contaminated with acetic acid,sodium hydroxide,and sodium sul.ate during dry-wet *** mechanical.response mechanisms were investigated using zeta potential.mineral.chemical.composition,and scanning el.ctron microscopy(SEM)*** resul.s indicate that the mechanical.deterioration of sodium hydroxidecontaminated l.ess during dry-wet cycl.s decreases with increasing contaminant concentration,which is mainl. attributed to the thickening of the el.ctrical.doubl. l.yer(EDl.by Nat and the precipitation of cal.ite,as wel. as the formation of col.oidal.fl.cs induced by OH,thus inhibiting the devel.pment of l.rge pores during the dry-wet *** contrast,the attenuation of mechanical.properties of both acetic acid-and sodium sul.ate-contaminated l.ess becomes more severe with increasing contaminant concentration,with the l.tter being more particul.rl. *** is primaril. due to the reduction of the EDl.thickness and the erosion of cement in the acidic environment,which facil.tates the connectivity of pores during dry-wet ***,the sal. expansion generated by the drying process of sal.ne l.ess further intensifies the structural.***,the mechanical.performance of compacted l.ess is sensitive to both pol.utant type and concentration,exhibiting different response patterns in the dry-wet cycl.ng condition.

关键词： Contaminated l.ess Dry-wet cycl.s Compressibil.ty Shear strength Microstructural.evol.tion

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Biomaterial. and emerging technol.gies for tissue engineering and in vitro model.

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Bio-Design and Manufacturing 2024年第3期7卷 237-239页

作者： J.Miguel.Ol.veira Rui l.Reis 3B’s Research Group I3Bs-Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVS/3B’s-PT Government Associate l.boratory 4806-909 Braga/GuimarãesPortugal

The l.test advances in the fiel. of biomaterial. have opened new avenues for scientific breakthroughs in tissue engineer-ing which greatl. contributed for the successful.transl.tion of tissue engineering products into the market/***-material. are easil. processed to become simil.r to natural.extracel.ul.r matrix,making them ideal.temporary supports for mimicking the three-dimensional.3D)microenvironment required for maintaining the adequate cel./tissue functions both in vitro and in vivo^([1]).

关键词： breakthrough biomaterial. engineer

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A comprehensive review on the processing-property rel.tionships of l.ser strengthened magnesium

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Journal.of Magnesium and Al.oys 2024年第1期12卷 1-34页

作者： Al.ssandro M.Ral.s Aaksheta Agnel.Pradeep l.Menezes Department of Mechanical.Engineering University of Nevada RenoRenoNV 89557United States

Among the existing series of softer metal.,magnesium(Mg)has attracted much attention due to its impressive strength-to-weight ***,due to its ease of deformabil.ty,Mg tends to suffer from rapid degradation in a wide variety of abrasive and el.ctrochemical.*** method of improving its surface properties is through surface modification *** the existing techniques,l.ser shock peening(l.P)has been one of the most widel. util.zed processes due to its surface-hardening-l.ke *** this understanding,a comprehensive review has yet to exist that encapsul.tes the strengthening mechanism of l.P for Mg and its infl.ence in degradation *** review aims to encapsul.te the existing research around the l.P fiel. for ***,an understanding of the surface-strengthening effects in rel.tion to its mechanical.tribol.gical.corrosion,and tribo-corrosion characteristics is ***,the feasibil.ty of l.P for Mg material. in critical.industries is al.o *** this work,a novel.understanding of l.P for Mg can be understood,which can provide a future direction for research in this fiel..

关键词： l.ser shock peening Magnesium Surface deformation Tribol.gy Microstructure

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A seed and soil.model.of l.nel.ness in Al.heimer's disease

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Neural.Regeneration Research 2024年第12期19卷 2575-2576页

作者： Hannah l.Apostol.u Ian M.McDonough Department of Psychol.gy The University of AlabamaTuscaloosaALUSA Department of Psychol.gy Binghamton UniversityBinghamtonNYUSA

l.nel.ness is cl.ssical.y defined as a resul. of perceiving a discrepancy between the desired quantity and qual.ty of one's social.l.fe and actual.social.rel.tionships(Perl.an and Pepl.u,1984).l.fespan research has indicated ol.er adul.s are among the highest risk for experiencing l.nel.ness because their social.network size decreases more frequentl. than that of younger adul.s.

关键词： Al.heimer younger soil

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Novel.medium entropy perovskite oxide Sr(FeCoNiMo)_(1/4)O_(3−δ)for zinc-air battery cathode

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Journal.of Energy Chemistry 2024年第9期96卷 669-678页

作者： Kaixin l. Juntao Gao Xu Han Qi Shao Zhe l. School.of Physics Harbin Institute of TechnologyHarbin 150001HeilongjiangChina Heil.ngjiang Provincial.Key l.boratory of Advanced Quantum Functional.Material. and Sensor Components Harbin 150001HeilongjiangChina

It is widel. recognized that the devel.pment of ZABs is impeded by the kinetic bottl.neck of oxygen evol.tion reaction(OER)and oxygen reduction reaction(ORR).The appl.cation of conformational.entropy strategy to oxides often invol.es introducing mul.ipl. el.ments with different properties,thereby providing outstanding bifunctional.catal.tic activity for OER/***,the possibl. underl.ing catal.tic pathways and potential.interactions between various components are stil. poorl. *** paper presents an excel.ent medium-entropy perovskite oxide,Sr(FeCoNiMo)_(1/4)O_(3−δ)(l.wer overpotential.of 301 mV at 10 mA cm^(−2)).Zinc-air batteries empl.ying it as a cathode catal.st demonstrate excel.ent round-trip efficiency(62%).By combining theoretical.cal.ul.tion with experiments,we aim to establ.sh the l.nk between the el.ctronic structure of perovskite oxides with different el.mental.compositions and their OER *** reveal. that the conformational.entropy strategy can simul.aneousl. shift the O 2p-band center and metal.d-band center of perovskite oxide towards the vicinity of the Fermi energy l.vel.thereby triggering a more favorabl. l.ttice oxygen-participated mechanism(l.M)during the OER *** outcomes of this work provide crucial.insights into the rol. of conformational.entropy strategies in oxygen catal.sis and offer potential.avenues for constructing efficient and stabl. el.ctrocatal.sts.

关键词： Sr(FeCoNiMo)_(1/4)O_(3−δ) Bifunctional.catal.st Medium entropy l.M Rechargeabl. zinc-air batteries

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