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Content analysis of systematic reviews on effectiveness ofTraditional Chinese Medicine

Journal of Traditional Chinese Medicine 2013年第2期33卷 156-163页

作者： Junwen Wang meng Cui Hongguan Jiao Yuanyuan Tong Jun Xu Yingkai Zhao Mei Han jianping Liu Institute of Information onTraditional Chinese Medicine China Academy of Chinese Medical SciencesCACMS Center for Evidence Based Chinese Medicine Beijing University of Chinese Medicine

OBJECTIVE:To evaluate evidence for the efficacy of Traditional Chinese Medicine(TCM) in systematic ***:Chinese(TCM Periodical Literature Database,Chinese Biological Medicine database,Chinese Medical Current Contents,China Hospital Knowledge Database journal fulltext database,Virtual Machining and Inspection System,and Wanfang) and English(Cochrane Database of Systematic Reviews,PubMed and Embase) databases were ***:Three thousand,nine hundred and fifty-five articles were initially identified,606 of which met the inclusion criteria,including 251 in English(83 from the Cochrane Database) and 355 in *** number of articles published each year increased between 1989 and *** disease was the most studied target *** measures included TCM preparations(177 articles),acupuncture(133 articles) and combinations of TCM and Western Medicine(38 articles).Control measures included positive medical(177 articles),basic treatment(100 articles),placebo(219 articles),and blank and mutual(107 articles).All articles included at least one reference;the greatest number was *** of 10 articles with high quality references demonstrated curative effectsagainst target diseases including upper respiratory tract infection,dementia and *** that were not recommended were tripterygium for rheumatoid arthritis and TCM syndrome differentiation for pediatric *** 10.4% of the studies,the authors concluded that the intervention had a curative *** assessors agreed with the authors' conclusions in 88.32% of cases,but rejected 8.94%(54 articles).CONCLUSION:1) Training in systematic review methods,including topic selection,study design,methods and technology,should be improved.2) Upper respiratory tract infection,dementia and depression may become the predominant diseases treated by TCM,and the corresponding interventions could be developed into practical applications.3) Use of non-recommended inter

关键词： Evidence-based medicine Systematicreview Traditional Chinese Medicine Curative ef-fect Content analysis

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Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

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Frontiers of Medicine 2015年第2期9卷 139-145页

作者： jianping Ye Antioxidant and Gene Regulation Laboratory Pennington Biomedical Research Centel Louisiana State University System Baton Rouge LA70808 USA

In obesity, chronic inflammation is believed to induce insulin resistance and impairs adipose tissue function. Although this view is supported by a large body of literature, it has been challenged by growing evidence that pro-inflammatory cytokines may favor insulin sensitivity through induction of energy expenditure. In this review article, interleukin 15 （IL-15） is used as a new example to explain the beneficial effects of the pro- inflammatory cytokines. IL-15 is secreted by multiple types of cells including macrophages, neutrophils and skeletal muscle cells. IL-15 expression is induced in immune cells by endotoxin and in muscle cells by physical exercise. Its transcription is induced by transcription factor NF-KB. IL-15 binds to its receptor that contains three different subunits （~, [5 and 1,） to activate JAK/STAT, PI3K/Akt, IKK/NF-KB and JNK/API pathways in cells. In the regulation of metabolism, IL-15 reduces weight gain without inhibiting food intake in rodents. IL-15 suppresses lipogenesis, stimulates brown fat function, improves insulin sensitivity through weight loss and energy expenditure. In human, circulating IL-15 is negatively associated with body weight. In the immune system, IL-15 stimulates proliferation and differentiation of T cells, NK cells, monocytes and neutrophils. In the anti-obesity effects of IL-15, T cells and NK cells are not required, but leptin receptor is required. In summary, evidence from human and rodents supports that the pro-inflammatory cytokine IL-15 may enhance energy expenditure to protect the body from obesity and type 2 diabetes. The mechanism of IL-15 action remains to be fully uncovered in the regulation of energy expenditure.

关键词： inflammation obesity cytokine energy expenditure insulin resistance

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Task-Space Tracking Control of Robotic Manipulator Via Intermittent Controller

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Journal of Systems Science & Complexity 2022年第6期35卷 2248-2262页

作者： MA Mihua CAI jianping School of Mathematics and Statistics Minnan Normal UniversityZhangzhou 363000China

An intermittent controller for robotic manipulator in task space was developed in this *** task space,for given a desired time-varying trajectory,the robot end-effector can track the desired target under the designed intermittent *** from most of the existing works on control of robotic manipulator,the intermittent control for robotic manipulator is discussed in task space instead of joint ***,the desired trajectory can be time-varying and not limited to *** a direct application,the authors implemented the proposed controller on tracking of a two-link robotic manipulator in task *** simulations demonstrate the effectiveness and feasibility of the proposed intermittent control strategy.

关键词： Intermittent controller robotic manipulator task-space tracking

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富血小板血浆来源的血小板细胞外囊泡分离技术与应用

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中国组织工程研究 2025年第1期29卷 156-163页

作者：李娇李晓丰李剑平辽宁省血液中心辽宁省输血医学研究所辽宁省沈阳市110044 中国医科大学药学院辽宁省沈阳市110122 哈尔滨市血液中心黑龙江省哈尔滨市150056 中国科学院苏州生物医学工程技术研究所江苏省苏州市215000

背景:血小板细胞外囊泡是循环中最丰富的囊泡,富含丰富的生物活性分子、遗传物质及蛋白质等信息分子,参与细胞通讯和物质交换,不仅具有良好的促凝活性,还具有促进组织修复和再生的巨大潜力,在再生医学具有广泛的应用前景。目的:从血小... 详细信息

背景:血小板细胞外囊泡是循环中最丰富的囊泡,富含丰富的生物活性分子、遗传物质及蛋白质等信息分子,参与细胞通讯和物质交换,不仅具有良好的促凝活性,还具有促进组织修复和再生的巨大潜力,在再生医学具有广泛的应用前景。目的:从血小板细胞外囊泡的分泌机制、在再生医学领域的应用及临床转化的限制因素进行阐述,为血小板细胞外囊泡的临床转化提供一些理论支撑。方法:应用计算机检索2005年1月至2023年8月PubMed数据库与血小板细胞外囊泡有关的文章,英文检索词为“platelet-derived,plateletrich plasma,extracellular vesicles,isolated,microvesicles exosomes,applications”,最后纳入符合主题标准的文献62篇进行综述分析。结果与结论:(1)活化的血小板细胞外囊泡可产生血小板微囊泡和血小板外泌体两种类型的囊泡,前者的分泌可能与肌动蛋白细胞骨架的不对称性相关,后者的分泌可能与H^(+)-ATP酶的调节相关。(2)血小板细胞外囊泡是血小板浓缩物和血小板本身的潜在效应物,可能通过促进血管生成、影响细胞行为、促凝与止血以及发挥炎症作用等几方面影响组织再生。(3)血小板细胞外囊泡在组织损伤、肌肉再生、软骨再生、骨关节炎等再生医学领域已有临床前报道,作为伤口愈合的潜在治疗方法已有临床试验数据,但血小板细胞外囊泡的分离方法、样本来源以及激活剂的种类等因素限制了血小板细胞外囊泡在再生医学领域的临床转化。(4)未来血小板细胞外囊泡可能成为再生医学中替代富血小板血浆的无细胞疗法,其临床转化还需要积极寻找鉴别血小板细胞外囊泡和血小板外泌体的特异性标志物,在激活剂刺激血小板细胞外囊泡产生的机制以及血小板细胞外囊泡的最佳收集方式、最佳储存方法、保质期限、临床应用的推荐剂量和最佳临床适应证还需要继续深入研究。

关键词：血小板来源富血小板血浆血小板裂解液细胞外囊泡微泡外泌体分离治疗组织损伤应用

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Subduction and retreating of the western Pacific plate resulted in lithospheric mantle replacement and coupled basin-mountain respond in the North China Craton

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Science China Earth Sciences 2018年第4期61卷 406-424页

作者： jianping ZHENG Hongkun DAI School of Earth Sciences State Key Laboratory of Geological Processes and Mineral Resources China University of GeosciencesWuhan

The North China Craton(NCC) witnessed Mesozoic vigorous tectono-thermal activities and transition in the nature of deep lithosphere. These processes took place in three periods:(1) Late Paleozoic to Early Jurassic(~170 Ma);(2) Middle Jurassic to Early Cretaceous(160-140 Ma);(3) Early Cretaceous to Cenozoic(140 Ma to present). The last two stages saw the lithospheric mantle replacement and coupled basin-mountain response within the North China Craton due to subduction and retreating of the Paleo-Pacific plate, and is the emphasis in this paper. In the first period,the subduction and closure of the PaleoAsian Ocean triggered the back-arc extension, syn-collisional compression and then post-collisional extension accompanied by ubiquitous magmatism along the northern margin of the NCC. Similar processes happened in the southern margin of the craton as the subduction of the Paleo-Tethys ocean and collision with the South China Block. These processes had caused the chemical modification and mechanical destruction of the cratonic margins. The margins could serve as conduits for the asthenosphere upwelling and had the priority for magmatism and deformation. The second period saw the closure of the Mongol-Okhotsk ocean and the shear deformation and magmatism induced by the drifting of the Paleo-Pacific slab. The former led to two pulse of N-S trending compression(Episodes A and B of the Yanshan Movement) and thus the pre-existing continental marginal basins were disintegrated into sporadically basin and range pro vince by the Mesozoic magmatic plutons and NE-SW trending *** the anticlockwise rotation of the Paleo-Pacific moving direction, the subduction-related magmatism migrated into the inner part of the craton and the Tanlu fault became normal fault from a sinistral one. The NCC thus turned into a back-arc extension setting at the end of this period. In the third period, the refractory subcontinental lithospheric mantle(SCLM) was firstly remarkably eroded and thin

关键词： Paleo-Pacific slab Subduction and retreating Mantle replacement Mountain-basin coupling North China Craton Deep processes and shallow response Yanshan Movement

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Importance of identifying tropical cyclone tornadoes in typhoon warning and defense systems

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Science Bulletin 2019年第3期64卷 143-145页

作者： Dan Yao Xudong Liang Qing meng Jian Li Chong Wu Zhengshuai Xie Dandan Chen jianping Guo State Key Laboratory of Severe Weather Chinese Academy of Meteorological Sciences

Tornadoes are highly localized severe weather phenomena and have been of increasing concern in China [1] in recent years, especially after the sinking of the Oriental Star in 2015 [2] and severe tornado damage in Yancheng in 2016 (3)Tornadoes induced by tropical cyclones, however, have received little attention.A recent study has shown that a large number of tornado-scale vortices can be produced at the inner edge of the intense eyewallconvection of tropical cyclones [4].

关键词： tropical cyclone defense systems UAV LST

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Clustering-based maintainability demonstration for complex systems with a mixed maintenance time distribution

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Journal of Systems Engineering and Electronics 2019年第6期30卷 1260-1271页

作者： WU Zhenya HAO jianping Department of Equipment Command and Management Shijiazhuang Campus of Army Engineering University

During maintainability demonstration,the maintenance time for complex systems consisting of mixed technologies generally conforms to a mixture *** existing maintainability standards and guidance do not explain explicitly how to deal with this *** paper develops a comprehensive maintainability demonstration method for complex systems with a mixed maintenance time *** of all,a K-means algorithm and an expectation-maximization(EM)algorithm are used to partition the maintenance time data for all possible *** Bayesian information criterion(BIC)is then used to choose the optimal *** this,the clustering results for equipment are obtained according to their degree of *** degree of similarity for the maintainability of different kinds of equipment is then determined using the projection *** using a Bootstrap method,the prior distribution is obtained from the maintenance time data for the most similar ***,a test method based on Bayesian theory is outlined for the maintainability ***,the viability of the proposed approach is illustrated by means of an example.

关键词： complex system maintainability demonstration mix ture distribution model Bayesian test.

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Microwave photonics

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Science China(Information Sciences) 2022年第12期65卷 49-112页

作者： jianping YAO Jose CAPMANY Microwave Photonics Research Laboratory School of Electrical Engineering and Computer Science University of Ottawa ITEAM Research Institute Universitat Politècnica de València iPronics Programmable Photonics

Microwave photonics, an interdisciplinary field that combines microwave engineering and photonic technology for the generation, transmission, processing, and control of microwave signals, to take advantage of the broad bandwidth, high frequency, and low loss offered by modern photonics, has been intensively researched for the last few decades, and numerous solutions have been proposed and demonstrated. In this article, an overview about microwave photonics is provided which covers the basic concepts of microwave photonics, photonic-assisted microwave signal generation, photonic-assisted microwave signal processing, and true time delay beamforming. The implementation of microwave photonic systems based on photonic integrated circuits is also reviewed, including the design, fabrication, and material platforms, application-specific photonic integrated circuits for microwave photonics, and programmable integrated microwave *** challenges and future applications of microwave photonics are also discussed.

关键词： microwave photonics photonic integrated circuits microwave photonic link microwave photonic signal processor optoelectronic oscillator radio over fiber

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Synthesis-free directional modulation for retrodirective frequency diverse array

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Science China(Information Sciences) 2020年第10期63卷 152-173页

作者： Sheng KE jianping AN Shuai WANG School of Information and Electronics Beijing Institute of Technology

Combination of directional modulation(DM) and frequency diverse array(FDA) provides a novel opportunity for enabling physical layer security because of the enhanced ability of distance ***, in the existing studies, the time-varying nature of the FDA pattern is usually ignored. In this paper, a modified model of FDA-DM is proposed, in which the ignored time factor in the previous studies is taken into consideration for providing a new and more accurate perspective on evaluating the security of FDA-DM. Furthermore, we reveal that FDA-DM can achieve angle-dependent and directional-time-coupleddependent security. After that, based on the retrodirective FDA(RFDA) with a new structure, a novel synthesis-free FDA-DM scheme is proposed for both overcoming the limitations of the FDA-DM scheme and allowing self-tracking the position of the pilot signal without any prior knowledge. Meanwhile, a new set of nonlinear frequency offsets, defined as rearranged linear frequency offsets(RLFOs), is also proposed for both combining the advantages of the linear/nonlinear frequency offsets and bringing conveniences to practical implementation. In addition, the closed-form expression of the average signal-to-artificial-noise-ratio(SANR)is given out for evaluating the security performance of the proposed scheme. Finally, numerical results are presented to verify both the accuracy of the proposed theoretical analysis and the superiority of the RFDADM scheme.

关键词： secure transmission frequency diverse array (FDA) frequency offsets (FOs) retrodirective array average SANR distribution

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Metal-carbene unit: a universal tool towards high-efficient photochemical reaction in solution

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Science China Chemistry 2019年第6期62卷 655-656页

作者： Chen Cao jianping Lang College of Chemistry Chemical Engineering and Materials Science Soochow University

Topochemically-controlled stereoselective [2+2] photocycloadditions are now well-established in the literatures. The construction of cyclobutane rings has attracted considerable attention due to the existence of this structural motif in natural products and synthetic medicines. Furthermore, cyclobutane derivatives appended with pyridyl or carboxylic groups exhibit intriguing properties in some advanced formation of metallo-supramolecular assemblies and materials. Generally, the photochemical [2+2] cycloaddition reactions are reported to take place in the solid state.

关键词： materials state place

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