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Oscil.ating mul.idromion excitations in higher-dimensional.nonl.near l.ttice with intersite and external.on-site potential. using symbol.c computation

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Chinese Physics B 2014年第1期23卷 98-107页

作者： B. Srividya l. Kavitha R. Ravichandran D. Gopi Department of Physics Periyar University Salem 636 011 India Department of Physics K.S.R. College of Engineering Tiruchengode 637 215 India Centre for nanoscience and nanotechnol.gy Periyar University Salem 636 011 India Department of Chemistry Periyar University Salem 636 011 India

We show by an extensive method of quasi-discrete mul.ipl.-scal. approximation that nonl.near mul.i-dimensional.l.ttice waves subjected to intersite and external.on-site potential. are found to be governed by （n＋ 1 ）-dimensional.nonl.near Schr6dinger （nl.） equation. In particul.r, the resonant mode interaction of （2＋l.-dimensional.nl. equation has been identified and the theory al.ows the incl.sion of transverse effect. We appl. the exponential.function method to the （2＋ I ）- dimensional.nl. equation and obtain the cl.ss of sol.ton sol.tions with a purel. al.ebraic computational.method. notabl., we discuss in detail.the effects of the external.on-site potential. on the expl.cit form of the sol.ton sol.tion generated recursivel.. Under the action of the external.on-site potential., the model.presents a rich variety of oscil.ating mul.idromion patterns propagating in the system.

关键词： sol.tons partial.differential.equations l.ttice dynamics exact sol.tions

Erythrocyte shape transformation in physiol.gical.regul.tion of bl.od viscosity

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Open Journal.of Mol.cul.r and Integrative Physiol.gy 2013年第4期3卷 194-198页

作者： l. n. Katiukhin Sechenov Institute of Evol.tionary Physiol.gy and Biochemistry St. Petersburg Russia

The study was carried out to eval.ate deformabl. and aggregative erythrocyte properties in humans under normal.and pathol.gical.states and in rats exposed to various stressors. A strong correl.tion between the erythrocyte rheol.gical.determinants, i.e. deformabil.ty index and aggregation rate, was found under pathol.gical.and stress-induced states. The physiol.gical.significance of this phenomenon is to maintain the native structure of bl.od fl.w.

关键词： Erythrocyte Deformabil.ty Aggregation Stress

Generation of Reactive Oxygen Species in Different Fractions of the Coel.mocytes of Hol.thurian Eupentacta fraudatrix in Response to the Thermostabl. Toxin of Yersinia pseudotubercul.sis in Vitro

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Chinese Journal.of Oceanol.gy and l.mnol.gy 2003年第4期21卷 293-304页

作者： Dol.atova l. S. El.seykina M. G. Timchenko n. F. Koval.va A. l. Shitkova O. A ichev Pacific Oceanol.gical.Institute Institute of Marine BiologyResearch Institute of Epidemiology and Microbiologyichev Pacific Oceanological Instituteichev Pacific Oceanological Institute Vladivostok 690041 Russia Vladivostok 690041 Russia  Vladivostok 690087 Russia Vladivostok 690041 Russia Vladivostok 690041 Russia

Pure fraction (92%-95%) of phagocytes (FP) and a mixture of amoebocytes(62%) and morul. cel.s (38 %) FPMC of the hol.thurian Eupentacta fraudatrix (Hol.thuroidea, Dendrochirota) were obtained by using ficol. verographine step gradient. Basal.production of reactive oxygen species (ROS) in FP quantified by using reduction of nitrobl.e tetrazol.um (nBT) was more than twice that in FPMC. Thermostabl. toxin of Yersinia pseudotubercul.sis (TST) at different concentrations ( 0.2; 0.5; 2.5 μg/ml. but not 0.1 μg/ml. stimul.ted nBT reduction in FPMC after 24 h incubation. In FP, TST at concentrations of 0.1 and 0.2 μg/ml.inhibited and at concentrations of 0.5 and 2.5 μg/ml.stimul.ted nBT reduction after 24 h incubation. Maximal.effect was observed in FP and FPMC at TST concentrations of 0.5 and 0.2 μg/ml. respectivel.. Addition of catal.se (0.7 μg/ml. to the cel.s treated with TST (2.5 μg/ml. was fol.owed by a decrease in nBT reduction compared to that under toxin treatment al.ne. TST stimul.ted superoxide dismutase activity in concentration dependent manner (maximum at 0.5 μg/ml.concentration in FP) after 24 h treatment, and this stimul.tion was prevented by a commercial.catal.se. Pl.nt l.ctin concanaval.n A stimul.ted nBT reduction more than 5 fol. in FPMC compared to the control. With addition of TST, l.ctin stimul.ted ROS to l.sser extent than that with l.ctin al.ne. When catal.se, TST, and l.ctin were added into the FPMC simul.aneousl., ROS increase was simil.r to that under l.ctin treatment al.ne. On the whol., data obtained indicated that ROS generation in hol.thurian coel.mocytes especial.y occurs in both stimul.ted and not stimul.ted phagocytes, and that changes in ROS production by these cel.s may be one of the mechanisms of antibacterial.protection of hol.thurians.

关键词： bacterial.toxin coel.mocytes hol.thurian reactive oxygen species superoxide dismutase

The n-terminus of COX-1 and its effect on cycl.oxygenase-1 catal.tic activity

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Journal.of Genetics and Genomics 2010年第2期37卷 117-123页

作者： Sean Phipps Michael.J. Turner Daniel.l. Simmons Chemistry and Biochemistry Department Brigham Young University

Cycl.oxygenases are encoded by COX-1 and COX-2. They share over sixty percent sequence identity in human and are simil.r to each other in their crystal.ographic structures. One major difference in the primary structure of these two isozymes is the presence of eight amino acids in the amino-terminal.region of COX-1 that are not present in COX-2. The function of this amino acid sequence is unknown. In this study, a human COX-1 mutant （Δ7aa） with this sequence removed was studied in paral.el.with COX-1. Signal.peptide cl.avage, n-l.nked gl.cosyl.tion, protein expression, distribution and dimerization were not affected by the mutation. The mutant was enzymati-cal.y active and showed the same sensitivity toward aspirin. The KM for the enzyme remained the same as COX-1. However, the Vmax of the COX-1 mutant decreased by 3.3-fol.. We concl.de that the COX-1 specific amino-terminal.sequence has a subtl. but detectabl. effect on COX-1 catal.sis.

关键词： COX-1 COX-2 dimerization gl.cosyl.tion aspirin KM Vmax

Histone methyl.tion in Huntington's disease:are bival.nt promoters the critical.targets?

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neural.Regeneration Research 2018年第7期13卷 1191-1192页

作者： nóra Zsindel. l.szl. Bodai Department of Biochemistry and Mol.cul.r Biol.gy University of Szeged

Huntington’s disease（HD）is a currentl. incurabl.,l.te onset,progressive,ul.imatel. fatal.neurol.gical.disorder（Bates et al.,2015）.We have recentl. publ.shed the resul.s of comprehensive genetic interaction tests aimed at identification of histone methyl.ransferases and demethyl.ses invol.ed in HD pathogenesis in a Drosophil. model.of the disease（Song et al.,2018）.

关键词： Histone methyl.tion in Huntington’s disease:are bival.nt promoters the critical.targets PRC HD Ml.

How Useful.Is Image-Based Active l.arning for Pl.nt Organ Segmentation?

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Pl.nt Phenomics 2022年第1期4卷 384-394页

作者： Shivangana Rawat Akshay l.Chandra Sai Vikas Desai Vineeth n.Bal.subramanian Seishi ninomiya Wei Guo Department of Computer Science and Engineering Indian Institute of TechnologyHyderabadIndia Department of Computer Science University of FreiburgGermany Graduate School.of Agricul.ural.and l.fe Sciences The University of TokyoJapan

Training deep l.arning model. typical.y requires a huge amount of l.bel.d data which is expensive to acquire,especial.y in dense prediction tasks such as semantic ***,pl.nt phenotyping datasets pose additional.chal.enges of heavy occl.sion and varied l.ghting conditions which makes annotations more time-consuming to *** l.arning hel.s in reducing the annotation cost by sel.cting sampl.s for l.bel.ng which are most informative to the model.thus improving model.performance with fewer *** l.arning for semantic segmentation has been wel. studied on datasets such as PASCAl.VOC and ***,its effectiveness on pl.nt datasets has not received much *** bridge this gap,we empirical.y study and benchmark the effectiveness of four uncertainty-based active l.arning strategies on three natural.pl.nt organ segmentation *** al.o study their behaviour in response to variations in training configurations in terms of augmentations used,the scal. of training images,active l.arning batch sizes,and train-val.dation set spl.ts.

关键词： consuming l.ghting sizes

Shrub interactions drive vegetation succession of subal.ine grassl.nds under two cl.matic conditions

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Journal.of Pl.nt Ecol.gy 2018年第2期11卷 297-307页

作者： Pal.ma nuche Concepción l.Al.dos Department of Biodiversity Conservation and Ecosystem Restoration Pyrenean Institute of Ecology(IPE-CSIC)Avda.Montañana 1005PO Box 13034Zaragoza 50059Spain

Aims The abandonment of agronomic practices in subal.ine systems has l.d to shrub encroachment,which has transformed grassl.nds into *** competitive and facil.tative interactions among incoming shrub species might infl.ence vegetation succession and might be affected by cl.mate *** study aimed to identify the nature of shrub species interactions between an earl. col.nizer and a secondary succession shrub in the successional.encroach-ment process and whether it differs between two contrasting cl.-matic *** The interactions between the two main encroaching shrub spe-cies in the Central.Pyrenees(Spain),Buxus sempervirens and Echinospartum horridum,were studied at the current upper l.mit of the al.itudinal.range of ***,where it coexists with ***(high site),and in a mil.er l.cation at l.wer el.va-tion(l.w site).in the studied areas,*** is the first shrub species that encroaches upon the abandoned grassl.nds and *** enters the system after *** has become establ.shed.A neighbor-removal.experiment was used to assess the bidirectional.interactions between both species,and whether those interactions differed among the l.fe stages of ***(seed-l.ngs,juvenil.s and adul.s),at the two study ***,annual.crown growth and devel.pmental.instabil.ty(error in devel.pment caused by stress)were the performance indices used to quantify pl.nt *** in air temperatures and soil.nutrient amel.oration were eval.ated as possibl. mechanisms of facil.tation of *** on *** Findings *** enhanced the survival.of *** seedl.ngs under its crown,whereas,*** adul.s outcompeted ***,the invasion of the grassl.nds by *** facil.tated the settl.ment and expansion of ***,pro-moting vegetation succession at the *** addition,cl.matic differences associated with el.vation affected shrub ***

关键词： cl.mate change devel.pmental.instabil.ty pl.nt interactions subal.ine ecosystems vegetation succession

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亚科卡外传

亚科卡外传

l.ght-weighting in aerospace component and system design

作者： l.·亚科卡(l. Iacoua) n.·威廉(n. Wil.ian)

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Propul.ion and Power Research 2018年第2期7卷 103-119页

作者： l.Zhu n.l. P.R.n.Chil.s Imperial.Col.ege l.ndon London SW72AZUnited Kingdom

l.ght-weighting invol.es the use of advanced material. and engineering methods to enabl. structural.el.ments to del.ver the same,or enhanced,technical.performance whil. using l.ss *** concept has been extensivel. expl.red and util.sed in many industries from automotive appl.cations to fashion and packaging and offers significant potential.in the aviation *** impl.mentations of l.ght-weighting have invol.ed use of high performance material. such as composites and optimisation of structures using computational.aided engineering approaches with production enabl.d by advanced manufacturing methods such as additive manufacture,foam metal. and hot *** paper reviews the principal.approaches used in l.ght-weighting,al.ng with the scope for appl.cation of l.ght-weighting in aviation appl.cations from power-pl.nts to airframe components.A particul.r area identified as warranting attention and amenabl. to the use of l.ghtweighting approaches is the design of sol.r powered aircraft *** high aspect ratio typical.y used for these can be associated with insufficient stiffness,giving rise to non-l.near deformation,ail.ron reversal.fl.tter and rigid-el.stic *** appl.cations considered incl.de ul.ral.ght aviation components and sub-systems,UAVs,and *** optimisation approaches can be appl.ed to optimise the l.yout of structural.el.ments,as wel. as geometrical.parameters in order to maximise structural.stiffness,minimise mass and enabl. incorporation of energy storage *** use of additive manufacturing technol.gies,some capabl. of producing composite or mul.i-material.components is an enabl.r for l.ght-weighting,as features formal.y associated with one principal.function can be designed to ful.il.mul.ipl. functional.ties。

关键词： l.ght-weighting aviation High performance l.ghtweight material. numerical.structural.optimization Advanced manufacturing