检索结果-南通市图书馆

Application of Lattice Boltzmann Method to Simulate Forest Edge

在线全文

学校读者我要写书评

暂无评论

Advances in Applied Mathematics and Mechanics 2023年第2期15卷 376-401页

作者： Jie Wei Jianjun wu An Jiang Kun Wan Key Laboratory of Mechanics on Disaster and Environment inWestern China Attached to the Ministry of Education of ChinaLanzhou UniversityLanzhouGansu 730000China College of Civil Engineering and Mechanics Lanzhou UniversityLanzhouGansu 730000China Shenzhen TenFong Technology Co. LtdGuangdongChina ZhongJiao TianHe Machinery Equipment Manufacturing Co.LTD SuzhouJiangsuChina

This study is focused on the forest edge flow by using numerical method.To model the effects of a forest canopy on airflow,source terms are introduced into the governing equations.The lattice Boltzmann method in conjunction with the standard k-εmodel is applied to solve the turbulent wind field.In order to perform the simulation on non-uniform grids,the Taylor series expansion and least square based lattice Boltzmann method(TLLBM)is adopted to improve the accuracy and computational efficiency.The present method and code are verified with an earlier forest edge simulation.A series of forest canopies are established to explore the impacts of canopy morphology on wind field.These canopies cover 3 canopy architectures and the Leaf Area Index(LAI)ranges from 2.0 to 4.0.The further study is carried out by adjusting the canopy foliage amount and the canopy architecture.The present study demonstrates the potential of lattice Boltzmann method to simulate the high Re number forest edge flow.The impacts of canopy morphology on zero plane displacement,aerodynamic roughness length,friction wind velocity,permeability coefficient,wall-shear stress are illustrated in detail.The results show that the canopy sub-layer wind field,especially the wind velocity profiles within and above the forest canopy,are mainly determined by canopy morphology.

关键词： Forest edge lattice Boltzmann method non-uniform grids canopy morphology

An atmosphere-breathing propulsion system using inductively coupled plasma source

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2023年第5期36卷 223-238页

作者： Peng ZHENG Jianjun wu Yu ZHANG Bixuan CHE Yuanzheng ZHAO College of Aerospace Science and Engineering National University of Defense TechnologyChangsha 410073China

CubeSats have attracted more research interest recently due to their lower cost and shorter production time.A promising technology for CubeSat application is atmosphere-breathing electric propulsion,which can capture the atmospheric particles as propulsion propellant to maintain longterm mission at very low Earth orbit.This paper designs an atmosphere-breathing electric propulsion system for a 3 U CubeSat,which consists of an intake device and an electric thruster based on the inductively coupled plasma.The capture performance of intake device is optimized considering both particles capture efficiency and compression ratio.The plasma source is also analyzed by experiment and simulation.Then,the thrust performance is also estimated when taking into account the intake performance.The results show that it is feasible to use atmosphere-breathing electric propulsion technology for CubeSats to compensate for aerodynamic drag at lower Earth orbit.

关键词： Atmosphere-Breathing Electric Propulsion(ABEP) CubeSat Inductively coupled plasma Intake device Very Low Earth Orbit(VLEO)

Superplastic Tension Behavior of Dissimilar TC4/SP700 Laminate through Diffusion Bonding

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 2024年第2期37卷 353-363页

作者： Qianwen Zhang Tianle Li Yanbin Han Wei Zheng Xifeng Li Jianjun wu School of Mechanical Engineering Northwestern Polytechnical UniversityXi’an710072China AVIC Xi’an Aircraft Industry Group Company Ltd Xi’an710089China Institute of Forming Technology and Equipment School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai200030China

Superplastic forming is a practical method to manufacture complex-shaped parts of titanium alloys with large deformation.Laminated parts of dissimilar titanium alloys fabricated by superplastic forming can achieve excellent performance by combining the advantages of components.This work displays the superplastic tension behavior and microstructural evolution of dissimilar TC4/SP700 laminate prepared by the diffusion bonding process.Two titanium alloys can achieve metallurgical bonding at parameters of 800℃/1 h/5 MPa.Except for dynamic recrystallization and grain growth behaviors upon superplastic tension,stress-induced phase transformation plays an important role inαtoβphase transformation apart from the elevated temperature.The superplastic deformation can be attributed to the grain boundary sliding accommodated multiplex motion of dislocations.In addition,the retained strengths of all dissimilar TC4/SP700 laminates after superplastic deformation with different strain rates and temperatures range from 807 to 890 MPa.

关键词： TC4/SP700 laminate Diffusion bonding Microstructure Superplastic tension Strength

Advances in HIV Eradication Strategies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Microbes & Diseases 2022年第2期4卷 64-70页

作者： Qingmin Mei Wei Wang Jianjun wu Yong Gao The First Affiliated Hospital Division of Life Science and MedicineUniversity of Science and Technology of ChinaHefeiAnhuiChina Anhui Provincial Center for Disease Control and Prevention HefeiAnhuiChina

Although the advent of combination antiretroviral therapy can efficiently suppress human immunodeficiency virus(HIV)replication,a complete cure for HIV infection cannot be achieved due to the existence of latent viral reservoirs.In recent years,investigation of HIV cure strategies has become a hot topic in the field.In this article,we review the major barriers to HIV cure,compare the progress and challenges of non-specific and specific latent reversal agents in curing HIV,and discuss possible solutions to the current problems.

关键词： HIV latent reservoir latency reversing agents

A rare presentation of lung squamous cell carcinoma metastasis to the distal phalanx of the little finger:a case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Innovation 2022年第2期1卷 194-196页

作者： Jianjun wu Yinan Zhou Dawei Yang Fan Yang Department of Cardiology The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Key Laboratory of Myocardial Ischemia Ministry of EducationHarbin Medical UniversityHarbinChina Department of Digestive Internal Medicine The First Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Orthopedics The Fourth Affiliated Hospital of Harbin Medical UniversityHarbinChina

Lung cancer is one of the most common malignant tumors worldwide.Early detection is the most important factor that affects the prognosis of lung cancer patients.The distal phalanx is a highly unusual metastatic site of lung cancer,and is often misdiagnosed,especially when accompanied by trauma.Herein,we present the case of a 68‐year‐old male patient who injured his right little finger.We hope this rare case will help clinicians to better diagnosis acral metastases of lung cancer to prolong patient survival.

关键词： acrometastases lung neoplasm micro metastasis pulmonary disease

Reduced K-best sphere decoding algorithm based on minimum route distance and noise variance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2014年第1期25卷 10-16页

作者： Xinyu Mao Jianjun wu Haige Xiang School of Electronics Engineering and Computer Science Peking University

This paper focuses on reducing the complexity of K-best sphere decoding （SD） algorithm for the detection of uncoded multi-ple input multiple output （MIMO） systems. The proposed algorithm utilizes the threshold-pruning method to cut nodes with partial Euclidean distances （PEDs） larger than the threshold. Both the known noise value and the unknown noise value are considered to generate the threshold, which is the sum of the two values. The known noise value is the smal est PED of signals in the detected layers. The unknown noise value is generated by the noise power, the quality of service （QoS） and the signal-to-noise ratio （SNR） bound. Simulation results show that by considering both two noise values, the proposed algorithm makes an efficient reduction while the performance drops little.

关键词： chi-square distribution （CSD） K-best sphere decoding（SD） multiple input multiple output （MIMO） systems.

Stochastic dynamic simulation of railway vehicles collision using data-driven modelling approach

在线全文

学校读者我要写书评

暂无评论

Railway Engineering Science 2022年第4期30卷 512-531页

作者： ShaodiDong Zhao Tang Michelle wu jianjun Zhang State Key Laboratory of Traction Power Southwest Jiaotong UniversityChengdu 610031China National Centre for Computer Animation Bournemouth UniversityDorsetUK

Using stochastic dynamic simulation for railway vehicle collision still faces many challenges,such as high modelling complexity and time-consuming.To address the challenges,we introduce a novel data-driven stochastic process modelling(DSPM)approach into dynamic simulation of the railway vehicle collision.This DSPM approach consists of two steps:(i)process description,four kinds of kernels are used to describe the uncertainty inherent in collision processes;(ii)solving,stochastic variational inferences and mini-batch algorithms can then be used to accelerate computations of stochastic processes.By applying DSPM,Gaussian process regression(GPR)and finite element(FE)methods to two collision scenarios(i.***.lead car colliding with a rigid wall,and the lead car colliding with another lead car),we are able to achieve a comprehensive analysis.The comparison between the DSPM approach and the FE method revealed that the DSPM approach is capable of calculating the corresponding confidence interval,simultaneously improving the overall computational efficiency.Comparing the DSPM approach with the GPR method indicates that the DSPM approach has the ability to accurately describe the dynamic response under unknown conditions.Overall,this research demonstrates the feasibility and usability of the proposed DSPM approach for stochastic dynamics simulation of the railway vehicle collision.

关键词： Dynamic simulation Railway vehicle collision Stochastic process Data-driven stochastic process modelling

Coupling analysis of passenger and train flows for a large-scale urban rail transit system

在线全文

学校读者我要写书评

暂无评论

Frontiers of Engineering Management 2023年第2期10卷 250-261页

作者： Ping ZHANG Xin YANG Jianjun wu Huijun SUN Yun WEI Ziyou GAO State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong UniversityBeijing 100044China Beijing Mass Transit Railway Operation Corp.Ltd. Beijing 100044China

Coupling analysis of passenger and train flows is an important approach in evaluating and optimizing the operation efficiency of large-scale urban rail transit(URT)systems.This study proposes a passenger–train interaction simulation approach to determine the coupling relationship between passenger and train flows.On the bases of time-varying origin–destination demand,train timetable,and network topology,the proposed approach can restore passenger behaviors in URT systems.Upstream priority,queuing process with first-in-first-serve principle,and capacity constraints are considered in the proposed simulation mechanism.This approach can also obtain each passenger’s complete travel chain,which can be used to analyze(including but not limited to)various indicators discussed in this research to effectively support train schedule optimization and capacity evaluation for urban rail managers.Lastly,the proposed model and its potential application are demonstrated via numerical experiments using real-world data from the Beijing URT system(i.e.,rail network with the world’s highest passenger ridership).

关键词： urban rail transit coupling analysis passenger–train interaction large-scale simulation

Small molecule-based immunomodulators for cancer therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2022年第12期12卷 4287-4308页

作者： Yinrong wu Zichao Yang Kui Cheng Huichang Bi jianjun Chen Guangdong Provincial Key Laboratory of New Drug Screening NMPA Key Laboratory for Research and Evaluation of Drug MetabolismSchool of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China

Immunotherapy has led to a paradigm shift in the treatment of cancer.Current cancer immunotherapies are mostly antibody-based,thus possessing advantages in regard to pharmacodynamics(e.g.,specificity and efficacy).However,they have limitations in terms of pharmacokinetics including long half-lives,poor tissue/tumor penetration,and little/no oral bioavailability.In addition,therapeutic antibodies are immunogenic,thus may cause unwanted adverse effects.Therefore,researchers have shifted their efforts towards the development of small molecule-based cancer immunotherapy,as small molecules may overcome the above disadvantages associated with antibodies.Further,small molecule-based immunomodulators and therapeutic antibodies are complementary modalities for cancer treatment,and may be combined to elicit synergistic effects.Recent years have witnessed the rapid development of small molecule-based cancer immunotherapy.In this review,we describe the current progress in small molecule-based immunomodulators(inhibitors/agonists/degraders)for cancer therapy,including those targeting PD-1/PD-L1,chemokine receptors,stimulator of interferon genes(STING),Toll-like receptor(TLR),etc.The tumorigenesis mechanism of various targets and their respective modulators that have entered clinical trials are also summarized.

关键词： Cancer immunotherapy Small molecules Immunomodulators Inhibitors Agonists