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The super-pangenome of Populus unveils genomic facets for its adaptation and diversification in widespread forest trees

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Molecular Plant 2024年第5期17卷 725-746页

作者： Tingting Shi Xinxin Zhang Yukang Hou Changfu Jia Xuming Dan Yulin Zhang Yuanzhong Jiang Qiang Lai Jiajun feng jianju feng Tao Ma Jiali Wu Shuyu Liu Lei Zhang Zhiqin Long Liyang Chen Nathaniel R.Street Par K.Ingvarsson Jianquan Liu Tongming Yin Jing Wang Key Laboratory for Bio-Resources and Eco-Environment of Ministry of Education College of Life SciencesSichuan UniversityChengduSichuanChina College of Horticulture and Forestry Tarim UniversityAlar 843300China Umea Plant Science Centre Department of Plant PhysiologyUmea UniversityUmeaVasterbottenSweden Linnean Centre for Plant Biology Department of Plant BiologyUppsala BioCenterSwedish University of Agricultural SciencesUppsalaSweden The Key Laboratory of Tree Genetics and Biotechnology of Jiangsu Province and Education Department of China Nanjing Forestry UniversityNanjingJiangsuChina

Understanding the underlying mechanisms and links between genome evolution and adaptive innovations stands as a key goal in evolutionary ***,among the world’s most widely distributed and cultivated trees,exhibit extensive phenotypic diversity and environmental *** this study,we present a genus-level super-pangenome comprising 19 Populus genomes,revealing the likely pivotal role of private genes in facilitating local environmental and climate *** the integration of pangenomes with transcriptomes,methylomes,and chromatin accessibility mapping,we unveil that the evolutionary trajectories of pangenes and duplicated genes are closely linked to local genomic landscapes of regulatory and epigenetic architectures,notably CG methylation in gene-body *** comparative genomic analyses have enabled the identification of 142202 structural variants across species that intersect with a significant number of genes and contribute substantially to both phenotypic and adaptive *** have experimentally validated a∼180-bp presence/absence variant affecting the expression of the CUC2 gene,crucial for leaf serration ***,we developed a user-friendly web-based tool encompassing the multi-omics resources associated with the Populus super-pangenome(http://***).Together,the present pioneering super-pangenome resource in forest trees not only aids in the advancement of breeding efforts of this globally important tree genus but also offers valuable insights into potential avenues for comprehending tree biology.

关键词： Populus pangenomes whole-genome duplication structural variation genome evolution

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Research on Applications of Shenmai Injection on Hypertensive ICH Combined with Cerebrocardiac Syndromes

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Journal of Biosciences and Medicines 2021年第5期9卷 79-85页

作者： Gang Yang jianju feng Shaojun Yang Junjie Lv Donghai Yuan Chenbing Wang feng Ding Chao Gu Gaofeng Shao Department of Neurosurgery Zhuji Affiliated Hospital of Shaoxing University Shaoxing China Radiology Department Zhuji Affiliated Hospital of Shaoxing University Shaoxing China

Objective: This study is to observe the therapeutic effects of Shenmai injection on patients with hypertensive ICH and cerebrocardiac syndromes as well as its effects on prognosis. Methods: A total of 72 patients with severe hypertensive ICH and cerebrocardiac syndromes were selected and divided into the control group and the experimental group (Shenmai injection group) randomly, 36 patients in each group. The control group was treated by conventional therapy, while the experimental group was administrated by intravenous drip of the mixture of 50 ml Shenmai injection and 250 ml 5% glucose injection based on the treatment of the control group, once everyday, 2 weeks continuously. Results: Myocardial enzyme indexes of two groups at 3d, 7d and 14d were observed (Table 1). Myocardial enzyme index of the experimental group was improved quickly and significantly. Myocardial enzyme data of two groups at 3d, 7d and 14d were P Conclusions: Shenmai injection has some therapeutic effects on cerebral injuries and myocardial damages. It can treat brain and heart simultaneously, realize the goal of addressing both symptoms and root causes, and improve prognosis of patients with severe hypertensive ICH.

关键词： Hypertensive ICH Cerebrocardiac Syndromes Shenmai Injection

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Research on Correlation between TCM Syndrome Distribution Characteristics and Prognosis of Hypertensive Intracerebral Hemorrhage Operation

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Journal of Biosciences and Medicines 2021年第4期9卷 138-144页

Objective: This study is to analyze correlation between traditional Chinese medicine (TCM) syndrome distribution characteristics and prognosis of hypertensive intracerebral hemorrhage (HICH) operation. Methods: In this study, a total of 150 patients who had received HICH operation from April, 2017 to December, 2020 in our hospital and conformed to inclusion standards were selected. According to classification of TCM syndromes, amount of bleeding of patients was recorded through multiple radiological technologies, baseline information was collected, and prognosis was investigated. The final event was long-term follow-up visit of all-cause mortalities. Moreover, correlation between prognosis and TCM syndromes was analyzed. Results: It found through investigations that there are no statistically significant differences in composition ratio of TCM syndromes among patients with different genders and different age ranges (P > 0.05). Among so many TCM syndromes, bleeding amount of patients with declining vitality and distraction is the highest, while bleeding amount of patients with stirring wind due to yin deficiency is the lowest. With respect NIHSS scores, the patients with declining vitality and distraction show the highest NIHSS scores at admission and 10 d of the course of the disease, followed by patients with upward disturbance of wind-fire. There are statistically significant differences among these two groups (P Conclusions: Evolutionary characteristics of TCM syndromes of HICH are manifested by development from evidence-based symptoms to deficiency syndromes. Different syndromes are correlated with prognosis of patien

关键词： HICH TCM Syndromes Distribution Characteristics Prognosis Correlation

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经颅多普勒超声检查用于脑梗死患者颅内动脉狭窄的诊断价值

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中国基层医药 2022年第3期29卷 369-372页

作者：吴丹冯建钜诸暨市中医医院超声科诸暨311800 诸暨市人民医院放射科诸暨311800

目的评价经颅多普勒超声(TCD)用于诊断脑梗死患者颅内动脉狭窄的临床价值。方法选取2018年12月至2020年12月诸暨市中医医院收治的脑梗死患者120例为研究对象,所有患者均进行CT血管造影检测(CTA)和TCD检测,统计TCD和CTA检测对不同位置颅... 详细信息

目的评价经颅多普勒超声(TCD)用于诊断脑梗死患者颅内动脉狭窄的临床价值。方法选取2018年12月至2020年12月诸暨市中医医院收治的脑梗死患者120例为研究对象,所有患者均进行CT血管造影检测(CTA)和TCD检测,统计TCD和CTA检测对不同位置颅内动脉的狭窄情况的诊断结果,以CTA检测结果为金标准,统计TCD检测对不同位置颅内动脉狭窄的诊断效能指标,评价TCD与CTA检测对不同位置颅内动脉狭窄诊断结果的一致性。结果TCD检测对双侧大脑中动脉狭窄、大脑前动脉、大脑后动脉、基底动脉、双侧椎动脉和颈内动脉虹吸段狭窄的诊断灵敏度分别为89.47%、91.18%、85.00%、90.62%、81.82%和96.55%,TCD检测对不同位置颅内动脉狭窄的诊断特异度分别为87.30%、95.35%、91.25%、94.32%、96.33%和87.88%。TCD与CTA检测对双侧大脑中动脉狭窄、大脑前动脉、大脑后动脉、基底动脉、双侧椎动脉和颈内动脉虹吸段狭窄诊断结果的一致性Kappa值分别为0.766,0.858、0.758、0.833、0.800和0.852。结论TCD检测对于不同位置颅内动脉狭窄的诊断灵敏度和特异度均较高,与CTA检测结果一致性好,具有较高临床应用价值。

关键词：脑梗死颅内动脉疾病超声检查,多普勒,经颅脑血管造影术体层摄影术,X线计算机诊断价值灵敏度特异性一致性

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蓝光调控生物膜关键基因提高大肠杆菌耐酸性

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食品与发酵工业 2024年第15期50卷 1-7页

作者：吴建菊冯守帅江南大学生物工程学院工业生物技术教育部重点实验室江苏无锡214122

发酵过程中的酸胁迫限制了工业微生物的发展,精细调控生物膜形成是提升大肠杆菌耐酸性的有效策略。研究基于EL222蓝光诱导蛋白开发了具有8.6倍调控效率的双质粒调控系统,用于调节生物膜形成关键因子CsgD和二鸟苷酸环化酶M(diguanylate c... 详细信息

发酵过程中的酸胁迫限制了工业微生物的发展,精细调控生物膜形成是提升大肠杆菌耐酸性的有效策略。研究基于EL222蓝光诱导蛋白开发了具有8.6倍调控效率的双质粒调控系统,用于调节生物膜形成关键因子CsgD和二鸟苷酸环化酶M(diguanylate cyclase,DgcM)的表达。结果表明,在pH 5.0和15 mW/cm^(2)蓝光照射条件下,CsgD和DgcM过表达菌株耐酸性分别提高了22.3%和16.4%,生物膜含量分别增加了2.7倍和3.4倍。生物膜组成分析显示,酸性环境下多糖和蛋白质的增加以及可溶性微生物代谢产物的减少促进了细菌聚集,有助于形成更稳定的生物膜结构。实时荧光定量逆转录PCR结果证实生物膜形成相关基因转录水平显著提升。本研究构建的蓝光调控系统通过调控生物膜形成关键基因成功提高了大肠杆菌的耐酸性,这将为微生物的有机酸发酵提供参考和借鉴。

关键词：大肠杆菌蓝光调控生物膜耐酸性实时荧光定量逆转录PCR(RT-qPCR)

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沙棘植物资源的综合利用

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北方园艺 2002年第6期 24-25页

作者：王琳冯建菊蒋学玮塔里木农垦大学植物科技学院新疆阿拉尔843300

依据有关沙棘的研究文献 ,综述了沙棘的形态特征、生物学特征与分布及其生态效益、生化特性、医学用途、饮料、食品、化妆品生产中的应用、饲用价值等。

关键词：沙棘植物资源综合利用生态效益生化特性形态特征生物学特性

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北极新奥尔松地区常见大型真菌物种多样性及区系分析

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极地研究 2022年第2期34卷 139-148页

作者：何晨阳冯健举张涛余利岩中国医学科学院医药生物技术研究所中国药学微生物菌种保藏管理中心北京100050

北极新奥尔松地区(78°55′N,11°56′E)位于北极圈附近的斯瓦尔巴德群岛上,属于高北极地区。至今,对该地区大型真菌独特的物种多样性和生态分布规律研究较少。本研究以2019年(7—8月期间)采集自该地区的48份大型真菌标本为材料,通过形... 详细信息

北极新奥尔松地区(78°55′N,11°56′E)位于北极圈附近的斯瓦尔巴德群岛上,属于高北极地区。至今,对该地区大型真菌独特的物种多样性和生态分布规律研究较少。本研究以2019年(7—8月期间)采集自该地区的48份大型真菌标本为材料,通过形态特征和分子序列分析,鉴定出21种,隶属于1目、7科、10属,其中锈健孔菌(Arrhenia rustica)为斯瓦尔巴德群岛新记录种。此外,结合已报道的文献资料进行区系分析,显示该地区大型真菌物种具有明显的泛北极分布特征,以北温带-北极分布和北寒带分布成分为主。本研究丰富了对北极新奥尔松地区大型真菌物种多样性的认识,为研究气候变化对北极真菌物种多样性的影响提供了基础数据。

关键词：大型真菌物种多样性分子系统演化区系分析

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A novel method for AFRPs burrs removal:Principle of mechanochemo-induced fiber fracture

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Chinese Journal of Aeronautics 2024年第7期37卷 522-538页

作者： Jie XU Bo LI Pingfa feng Qiang WANG feng feng Division of Advanced Manufacturing Tsinghua Shenzhen International Graduate SchoolTsinghua UniversityShenzhen 518055China Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China Changhe Aircraft Industry(Group)Co.Ltd Jingdezhen 333000China

Burrs generated during the machining of Aramid-Fiber-Reinforced Composites(AFRPs)pose a challenge for the production efficiency of aircraft and helicopter housing *** studies have generally attempted to suppress burrs by referring to delamination suppression *** contrast to stratification,burrs are remediable machining *** such,a mechanochemical method with burrs trimming technological strategy are implemented to effectively combat ***,we clarify the mechanism by which aramid fibers cannot be cut off using analytical and numerical *** addition,the mechanism of fiber fracture with Modified Polyurethane Reactive Polymer(M-PUR),and development of anti-burr devices(thermostatic adhesive sealed generator)are ***,the experimental results show that the reduction rate in burr length is 87%-91%through the mechanochemical *** method not only opens a new avenue to solve the burr problem of aramid fibers but also builds an interdisciplinary bridge between polymer science and composite machining.

关键词： Mechanochemical method Burrs Orthogonal cutting Aramid fiber-reinforced composites Milling

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Record-high efficiency perovskite LEDs achieved by accelerating radiative recombination

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Science China Materials 2024年第9期67卷 3039-3040页

作者： feng Gao Department of Physics Chemistry and BiologyLinköping UniversityLinköping58183Sweden

Light-emitting diodes(LEDs)have revolutionized the lighting and displays due to their superior energy *** increasing demand for more efficient and brighter thin-film LEDs in flat-panel displays and solid-state lighting applications has driven extensive research into perovskite materials,which show great promise for high brightness and efficiency.

关键词： lighting radiative high

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Derivation of Expanded Isospectral-Nonisospectral Integrable Hierarchies via the Column-vector Loop Algebra

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 778-800页

作者： Hai-feng WANG Yu-feng ZHANG School of Science Jimei UniversityXiamen 361021China School of Mathematics China University of Mining and TechnologyXuzhou 221116China

A scheme for generating nonisospectral integrable hierarchies is *** on the method,we deduce a nonisospectral hierarchy of soliton equations by considering a linear spectral *** follows that the corresponding expanded isospectral and nonisospectral integrable hierarchies are deduced based on a 6 dimensional complex linear space ■.By reducing these integrable hierarchies,we obtain the expanded isospectral and nonisospectral derivative nonlinear Schr?dinger *** using the trace identity,the biHamiltonian structure of these two hierarchies are also ***,some symmetries and conserved quantities of the resulting hierarchy are discussed.

关键词： expanded isospectral-nonisospectral integrable hierarchies column-vector loop algebra bi-Hamiltonian structure symmetry

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