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锥头航行体高速斜入水的空泡流动特性数值研究

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中国造船 2024年第1期65卷 63-74页

作者：舒亮辛建建冯涛刘翔宇桂琴琴宁波大学船舶与海洋工程系宁波315211

数值研究弹体高速斜入水过程,考察空泡、流体动力特性和运动稳定性的变化规律。数值模型采用基于Realizable k-ε湍流模型的雷诺平均方法(RANS),并与模型试验结果进行对比,验证了该数值模型的精度。基于该方法模拟不同倾角下锥头弹体高... 详细信息

数值研究弹体高速斜入水过程,考察空泡、流体动力特性和运动稳定性的变化规律。数值模型采用基于Realizable k-ε湍流模型的雷诺平均方法(RANS),并与模型试验结果进行对比,验证了该数值模型的精度。基于该方法模拟不同倾角下锥头弹体高速斜入水过程,考察弹体入水从初始撞击、开空泡的形成与发展、颈缩、表面闭合和溃灭等多个阶段。研究表明:空泡表面闭合时间随倾角的增大而提前;在撞击水面瞬间,弹体表面承受巨大砰击载荷,在弹头形成局部高压,其峰值随倾角的增大而增大。随着入水倾角增大,弹体偏转角和横向位移减小,具有更好的弹道稳定性。

关键词：锥头弹体高速入水空泡流斜倾角数值模拟

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政治“自保”视域下明清官员的“隐语”现象

历史教学问题 2024年第1期 34-41,98,204,205页

作者：崔健健中国社会科学院大学历史学院 102488

明清时期封建专制皇权高度集中,官员、党派、政治集团之间斗争激剧,官场犯罪与反犯罪持续进行。此种政治环境下,官员行文时频繁使用的“隐语”,已逐渐脱离文字游戏的范畴,成为一种政治“自保”的常规手段。他们巧妙利用“隐语”之“遁... 详细信息

明清时期封建专制皇权高度集中,官员、党派、政治集团之间斗争激剧,官场犯罪与反犯罪持续进行。此种政治环境下,官员行文时频繁使用的“隐语”,已逐渐脱离文字游戏的范畴,成为一种政治“自保”的常规手段。他们巧妙利用“隐语”之“遁辞隐意”的秘密性和“谲譬指事”的指代性,来规避君主的禁忌文字、防范政敌的蓄意构陷以及遮掩自身的犯罪事实,反映的是一种畸形的官场生态。

关键词：明清官员 “隐语” “自保”

DMD模型鼠mdx小鼠线粒体损伤的研究进展

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中国实验动物学报 2024年第6期32卷 793-798页

作者：高天董健健喻绪恩安徽中医药大学神经病学研究所合肥230038 安徽中医药大学神经病学研究所附属医院合肥230061

Duchenne肌营养不良(Duchenne muscular dystrophy,DMD)是一种由编码抗肌萎缩蛋白的Dystrophin基因突变导致的致死性、进行性、X连锁隐性遗传肌肉疾病。目前,DMD尚无治愈手段,临床研究进展缓慢,动物模型的建立对DMD的实验研究作用越来... 详细信息

Duchenne肌营养不良(Duchenne muscular dystrophy,DMD)是一种由编码抗肌萎缩蛋白的Dystrophin基因突变导致的致死性、进行性、X连锁隐性遗传肌肉疾病。目前,DMD尚无治愈手段,临床研究进展缓慢,动物模型的建立对DMD的实验研究作用越来越重要。结合研究发现,mdx小鼠具有DMD患者相同的发病机制,广泛应用于DMD病理机制和新药开发的研究中。线粒体损伤是DMD重要的病理机制之一,对线粒体的保护是DMD的潜在治疗靶点,因此探讨mdx小鼠与线粒体损伤的关系具有重要意义。本文就近年来DMD模型鼠mdx小鼠线粒体损伤的研究进展进行综述,为相关实验提供参考。

关键词： Duchenne肌营养不良线粒体损伤动物模型 mdx小鼠

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畜禽呼吸测热装置的研究进展

动物营养学报 2024年第1期36卷 124-140页

作者：张建建王丽杨雪芬李平广东省农业科学院动物科学研究所猪禽种业全国重点实验室农业农村部华南动物营养与饲料重点实验室广东省畜禽育种与营养研究重点实验室岭南现代农业科学与技术广东省实验室茂名分中心广州510640

近年来随着呼吸测热装置的不断发展,不仅可应用于畜禽能量代谢,也在反刍动物温室气体测定等方面得到广泛应用。本文综述了呼吸测热装置的研究概况、呼吸面罩及呼吸室等的设计原理、装置构造和使用注意事项等方面的进展及其应用情况,以... 详细信息

近年来随着呼吸测热装置的不断发展,不仅可应用于畜禽能量代谢,也在反刍动物温室气体测定等方面得到广泛应用。本文综述了呼吸测热装置的研究概况、呼吸面罩及呼吸室等的设计原理、装置构造和使用注意事项等方面的进展及其应用情况,以期为畜禽能量代谢测定研究提供参考。

关键词：呼吸测热装置呼吸面罩呼吸室

Research on equipment fault diagnosis method based on random stochastic adaptive particle swarm optimization

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The Journal of China Universities of Posts and Telecommunications 2020年第4期27卷 17-25,42页

作者： Yang jianjian Zhang Qiang Wang Xiaolin Du Yibo Wang Chao Wu miao Department of Mechanical Electrical and Information EngineeringChina University of Mining and Technology(Beijing)Beijing 100083China Tian Di Science&Technology Co. LtdBeijing 100013China

The traditional fault diagnosis method of industrial equipment has low accuracy and poor applicability. This paper proposes a equipment fault diagnosis method based on random stochastic adaptive particle swarm optimization(RSAPSO). The entire model is validated by using the data of healthy bearings collected by Case Western Reserve University. Different gradient descent algorithms and standard particle swarm optimization(PSO) algorithms in a back propagation(BP) network are compared experimentally. The results show that the RSAPSO algorithm has a higher accuracy of weight threshold updating than the gradient descent algorithm and does not easily fall into a local optimum. Compared with PSO, it has a faster optimization speed and higher accuracy. Finally, the RSAPSO algorithm is validated with the data of bearings collected from the laboratory rotating machinery test bench and motor data collected from the tower reflux pump. The average recognition rate of the four kinds of bearing data constructed is 97.5%, and the average recognition rate of the two kinds of motor data reaches 100%, which prove the universality of the method.

关键词： fault diagnosis BP network gradient descent PSO algorithm

CNN coal and rock recognition method based on hyperspectral data

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International Journal of Coal Science & Technology 2022年第5期9卷 59-70页

作者： jianjian Yang Boshen Chang Yuchen Zhang Wenjie Luo Shirong Ge miao Wu School of Mechatronics and Information Engineering China University of Mining and Technology-BeijingBeijing 100083China Key Laboratory of Intelligent Mining and Robotics Ministry of Emergency ManagementBeijingChina

Aiming at the problem of coal gangue identifcation in the current fully mechanized mining face and coal washing,this article proposed a convolution neural network(CNN)coal and rock identifcation method based on hyperspectral ***,coal and rock spectrum data were collected by a near-infrared spectrometer,and then four methods were used to flter 120 sets of collected data:frst-order diferential(FD),second-order diferential(SD),standard normal variable transformation(SNV),and multi-style *** coal and rock refectance spectrum data were pre-processed to enhance the intensity of spectral refectance and absorption characteristics,as well as efectively remove the spectral curve noise generated by instrument performance and environmental factors.A CNN model was constructed,and its advantages and disadvantages were judged based on the accuracy of the three parameter combinations(i.e.,the learning rate,the number of feature extraction layers,and the dropout rate)to generate the best CNN classifer for the hyperspectral data for rock *** experiments show that the recognition accuracy of the one-dimensional CNN model proposed in this paper reaches 94.6%.Verifcation of the advantages and efectiveness of the method were proposed in this article.

关键词： Hyperspectral data Data pre-processing 1D-CNN Coal gangue identifcation

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统战工作的元问题与底层逻辑

上海市社会主义学院学报 2024年第4期210卷 98-107页

作者：姚俭建上海市社会主义学院上海200237

习近平总书记关于人心与统战工作关系的重要论述深刻阐发了“得民心者得天下,失民心者失天下”“人心向背定兴衰”的铁律,揭示了统战工作的元问题、底层逻辑及其本质要求。其中,一致性与多样性之间错综复杂关系的演进建构起了统战工作... 详细信息

习近平总书记关于人心与统战工作关系的重要论述深刻阐发了“得民心者得天下,失民心者失天下”“人心向背定兴衰”的铁律,揭示了统战工作的元问题、底层逻辑及其本质要求。其中,一致性与多样性之间错综复杂关系的演进建构起了统战工作底层逻辑;基于建构共同思想政治基础的大团结大联合则体现了统战工作底层逻辑的本质要求。

关键词：统战工作底层逻辑大团结大联合人心政治

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Chinese expert consensus on the diagnosis and treatment of balanoposthitis

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Chinese Medical Journal 2024年第13期137卷 1519-1521页

作者： Li Zhang Amer A.A.Abdulrahman Hao Guo Jia’an Zhang Xinghua Gao Weihua Pan Gang Wang Jinhua Xu Yuling Shi Liuqing Chen Hongxiang Chen Songmei Geng Yuping Ran Hongwei Wang Xiaoyong Man Jianmin Chang Furen Zhang Litao Zhang Guangwen Yin Jianzhong Zhang Wei Lai Zhibin Niu Hongkun Jiang Haibo Liu Yaolong Chen jianjian Wang Department of Dermatology The First Hospital of China Medical UniversityShenyangLiaoning 110001China Key Laboratory of Immunodermatology Ministry of Education and NHCNational Joint Engineering Research Center for Theranostics of Immunological Skin DiseasesShenyangLiaoning 110001China Department of Dermatology Chinese Academy of Medical Science and Peking Union Medical CollegeNanjingJiangsu 210042China Department of Dermatology Second Affiliated Hospital of Naval Medical UniversityShanghai 200003China Department of Dermatology Xijing HospitalFourth Military Medical UniversityXi’anShaanxi 710032China Department of Dermatology Huashan HospitalFudan UniversityShanghai 200040China Department of Dermatology Shanghai Skin Disease HospitalTongji University School of MedicineShanghai 200443China Department of Dermatology Wuhan No.1 HospitalWuhanHubei 430022China Department of Dermatology Huazhong University of Science and Technology Union Shenzhen HospitalShenzhenGuangdong 518052China Department of Dermatology Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710004China Department of Dermatovenereology West China HospitalSichuan UniversityChengduSichuan 610041China Department of Dermatology Huadong HospitalFudan UniversityShanghai 200040China Department of Dermatology Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310009China Department of Dermatology Beijing HospitalBeijing 100730China Shandong Provincial Hospital for Skin Diseases&Shandong Provincial Institute of Dermatology and Venereology Shandong First Medical University&Shandong Academy of Medical SciencesJinanShandong 250061China Department of Dermatology Tianjin Academy of Traditional Chinese Medicine Affiliated HospitalTianjin 300120China Department of Dermatology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Department of Dermatology Peking University People’s HospitalBeijing 100044 China Department of Dermatology Third Affi

Balanoposthitis(BP),a common male genitalia inflammation,is managed by clinicians from different specialties,including urology,pediatrics,dermatology,and *** to this diverse array of clinicians involved,there exists a lack of consistent,evidence-based recommendations for *** development of the consensus engaged 19 representative hospitals and it adhered to rigorous protocols,encompassing international registration(IPGRP-2021CN003)and the application of evidence grading criteria and recommendation standards[Appendix S1,Supplementary File,http://***/CM9/C42].Over the period from December 2020 to October 2022,consensus on 12 clinical issues was reached through comprehensive evidence searches and two iterations of Delphi surveys[Supplementary File,http://***/CM9/C42].

关键词： Delphi diagnosis rigorous

免疫检查点抑制剂在合并自身免疫性疾病肿瘤患者中的应用进展

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肿瘤研究与临床 2024年第4期36卷 317-320页

作者：刘洋吕建建李绪彤康复大学青岛医院(青岛市市立医院)肿瘤科青岛266071

免疫检查点抑制剂在肿瘤治疗中发挥着越来越重要的作用, 不断改写肿瘤治疗指南。免疫检查点抑制合并自身免疫性疾病的特殊人群中的应用目前尚缺乏明确且统一的治疗建议。文章对免疫检查点抑制剂在合并自身免疫性疾病患者抗肿瘤治疗中的... 详细信息

免疫检查点抑制剂在肿瘤治疗中发挥着越来越重要的作用, 不断改写肿瘤治疗指南。免疫检查点抑制合并自身免疫性疾病的特殊人群中的应用目前尚缺乏明确且统一的治疗建议。文章对免疫检查点抑制剂在合并自身免疫性疾病患者抗肿瘤治疗中的安全性和有效性进行分析及总结, 为临床医生制定治疗决策提供参考。

关键词：肿瘤免疫检查点抑制剂免疫系统疾病药物相关的副作用和不良反应