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Current progress of research on heat -resistant Mg alloys: A review

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International Journal of Minerals,Metallurgy and Materials 2024年第6期31卷 1406-1425页

作者： Hong Yang Wenlong Xie jiangfeng song Zhihua Dong Yuyang Gao Bin Jiang Fusheng Pan National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China

With the increasing attention received by lightweight metals,numerous essential fields have increased requirements for mag-nesium(Mg)alloys with good room-temperature and high-temperature mechanical properties.However,the high-temperature mechanic-al properties of commonly used commercial Mg alloys,such as AZ91D,deteriorate considerably with increasing temperatures.Over the past several decades,extensive efforts have been devoted to developing heat-resistant Mg alloys.These approaches either inhibit the gen-eration of thermally unstable phases or promote the formation of thermally stable precipitates/phases in matrices through solid solution or precipitation strengthening.In this review,numerous studies are systematically introduced and discussed.Different alloy systems,includ-ing those based on Mg–Al,Mg–Zn,and Mg–rare earth,are carefully classified and compared to reveal their mechanical properties and strengthening mechanisms.The emphasis,limitations,and future prospects of these heat-resistant Mg alloys are also pointed out and dis-cussed to develop heat-resistant Mg alloys and broaden their potential application areas in the future.

关键词： magnesium alloys mechanical properties heat resistance microstructures high temperatures strengthening mechanisms

Lutein-stevioside nanoparticle attenuates H_(2)O_(2)-induced oxidative damage in ARPE cells

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Food Science and Human Wellness 2024年第3期13卷 1628-1635页

作者： Zhuqing Dai Meimei Nie Ye Chen jiangfeng song Yayuan Xu Zhongyuan Zhang Guodong Zhang Shumo Yan Xing Zhang Dajing Li Institute of Agro-Product Processing Jiangsu Academy of Agricultural SciencesNanjing 210014China Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base Ministry of Science and TechnologyNanjing 210014China Jiangsu Aland Nutrition Co. Ltd.Taizhou 214500China Aland Nutrition Taizhou Co. Ltd.Taizhou 225300China

In order to improve the bioavailability of lutein(LUT),a novel lutein-stevio side nanoparticle(LUT-STE)were prepared previously,but the information about LUT-STE on protecting of eye health was limited.This study investigated the effect of LUT-STE on antioxidant activity of H_(2)O_(2)-induced human retinal pigment epithelial(ARPE)cells.LUT and LUT-STE(final concentration of 5μg/mL)significantly enhanced cell viability from(74.84±5.10)%to(81.92±10.01)%(LUT)and(89.33±4.34)%(LUT-STE),and inhibited the cell apoptosis(P<0.05).After pretreatment with LUT-STE in ARPE cells,the levels of superoxide dismutase(SOD),catalase(CAT)and glutathion peroxidase(GSH-Px)in ARPE cells were significantly increased(P<0.05),the contents of reactive oxygen species(ROS)and malondialdehyde(MDA)were decreased.In addition,the vascular endothelial growth factor(VEGF)levels were inhibited by 13.61%and 17.39%,respectively,pretreatment with LUT and LUT-STE.Western blotting results showed that the pretreatment with LUT-STE inhibited the expression of caspase-9 and caspase-3 and up-regulated Bcl-2/Bax pathway to inhibit H_(2)O_(2)-induced apoptosis.In summary,the novel delivery LUT-STE had more pronounced inhibitory effect on H_(2)O_(2)-induced damage in human ARPE cells.

关键词： Lutein Stevioside Antioxidant Human retinal pigment epithelial cell Mechanism

Targeting complement hyperactivation:a novel therapeutic approach for severe pneumonia induced by influenza virus/staphylococcus aureus coinfection

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Signal Transduction and Targeted Therapy 2024年第1期9卷 51-54页

作者： Leili Jia Haihua Luo Lizhong Li Mingyao Wang jiangfeng Liu Yuan Liang Shan Li Yong Jiang Juntao Yang Hongbin song Institute for Disease Control and Prevention of PLA BeijingChina Guangdong Provincial Key Laboratory of Proteomics State Key Laboratory of Organ Failure ResearchSchool of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515China State Key Laboratory of Common Mechanism Research for Major Diseases Institute of Basic Medical SciencesChinese Academy of Medical Science and Peking Union Medical College100005 BeijingChina

Dear Editor,Infections by the influenza virus are a significant and widespread global health threat,as these infections have an annual death toll ranging from 290,000 to 650,000.1 A significant proportion of these fatalities are attributed to secondary bacterial pneumonia,a severe complication commonly caused by ubiquitous respiratory pathogens such as Staphylococcus aureus(S.aureus).2 Of particular concern is the increased morbidity and mortality rates in individuals infected simultaneously with influenza virus and methicillin-resistant S.aureus(MRSA).3 The concurrent presence of bacteria and influenza virus usually causes acute respiratory distress syndrome(ARDS),which is associated with acute lung injury(ALI),severe lung tissue edema,and widespread inflammation.Nevertheless,determining the complex mechanisms underlying the synergistic interplay will require further investigation with a suitable coinfection mouse model.In our previous study,we utilized different sequential coinfections at various time points to model influenza A virus and MRSA coinfection.

关键词： influenza pneumonia lung

Controllable design of high-efficiency triboelectric materials by functionalized metal–organic frameworks with a large electronwithdrawing functional group

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Nano Research 2022年第10期15卷 9386-9391页

作者： Rongmei Wen Rui Feng Bo Zhao jiangfeng song Liming Fan Junyi Zhai Department of Chemistry College of ScienceNorth University of ChinaTaiyuan 030051China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400China College of Chemistry State Key Laboratory of Elemento-Organic ChemistryNankai UniversityTianjin 300071China

Triboelectric nanogenerator(TENG)can directly convert mechanical energy into electric energy.However,the triboelectric materials are limited to the triboelectric series.Here,for the first time,we choose the isostructural UiO-66-X(X=H,NH_(2),NO_(2),and Br)family as triboelectric materials to investigate the underlying relationships between different functional groups and the triboelectric performance of TENG.Unlike traditional triboelectric material organic polymers,metal–organic frameworks(MOFs)can be oriented design synthesis and functionalized with various functional groups.The results demonstrate that the largest output voltage and current are from UiO-66-NO_(2) TENG,and are about 23.79 V and 0.29μA,which are 3.19 and 4.14 times over that of the UiO-66 TENG,respectively.The working mechanism of the MOF TENG was discussed in depth through experiments and theoretical calculations.This work proves a novel strategy to obtain high output properties by functionalized MOFs with large electron-withdrawing functional groups and promising guidance for the choice of high-efficiency triboelectric materials.

关键词： triboelectric nanogenerator metal-organic frameworks UiO-66 functional group isostructural

Comparison of edge cracking and tensile cracking in in-situ deformation at 150℃of Mg-2Zn-1.5Mn alloy sheet

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Journal of Materials Science & Technology 2022年第17期112卷 24-35页

作者： Qiang Liu jiangfeng song Yuanding Huang Bin Jiang Biquan Xiao Fusheng Pan National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China MagIC-Magnesium innovation Centre Helmholtz-Zentrum GeesthachtMax-Planck-Str.121502 GeesthachtGermany

The Mg-2Zn-1.5Mn alloy(ZM21)sheets were hot-rolled in a single pass at 150℃with different reductions through on-line heating rolling.Microstructures and edge cracking behavior of the rolled sheets were investigated.The in-situ tensile tests at 150℃were also carried out,the crack initiation and propagation were compared with the edge cracking behavior of ZM21 sheets prepared by on-line heating rolling.The results reveal that the edge cracks are most likely to originate in the rolling direction and normal direction(RD-ND)plane due to the secondary tensile stress along RD.Edge cracking becomes more severe with an increasing reduction.The edge cracks mainly initiate and propagate in the fine recrystallized grain areas and the junction of recrystallized grains and sub-grains with hard orientation.The in-situ tensile test indicates that micro-cracks mainly initiate at the triple junction of grain boundaries where grains have hard orientation with low basal Schmid factor(SF).Meanwhile,those cracks are more likely to propagate along the grain boundaries with maximum difference in basal Schmid factor.Besides,the crack initiation and propagation during the in-situ tensile deformation at 150℃are found not to be associated with the recrystallization.

关键词： ZM21 Mg alloy On-line heating rolling In-situ tensile test Edge crack

Research advances of magnesium and magnesium alloys worldwide in 2021

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Journal of Magnesium and Alloys 2022年第4期10卷 863-898页

作者： jiangfeng song Jing Chen Xiaoming Xiong Xiaodong Peng Daolun Chen Fusheng Pan National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China Department of Mechanical and Industrial Engineering Ryerson UniversityTorontoOntario M5B 2K3Canada

More than 4000 papers in the field of Mg and Mg alloys were published and indexed in Web of Science(WoS)Core Collection database in 2021.The bibliometric analyses indicate that the microstructure,mechanical properties,and corrosion of Mg alloys still are the main research focus.Mg ion batteries and hydrogen storage Mg materials have attracted much attention.Significant contributions to the research and development of magnesium alloys were made by Chongqing University,Shanghai Jiaotong University,and Chinese Academy of Sciences in China,Helmholtz Zentrum Hereon in Germany,Ohio State University in the United States,the University of Queensland in Australia,Kumanto University in Japan,and Seoul National University in Korea,University of Tehran in Iran,etc..This review is aimed to summarize the progress in the development of structural and functional Mg and Mg alloys in 2021.Based on the issues and challenges identified here,some future research directions are suggested.

关键词： Magnesium alloys Cast magnesium alloys Wrought magnesium alloys Bio-magnesium alloys Mg based energy storage materials Processing technologies Corrosion and protection

Effect of sodium alginate-based hydrogel loaded with lutein on gut microbiota and inflammatory response in DSS-induced colitis mice

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Food Science and Human Wellness 2023年第6期12卷 2428-2439页

作者： Pengxiang Xu Shuwei Luo jiangfeng song Zhuqing Dai Dajing Li Cai’e Wu Institute of Agro-product Processing Jiangsu Academy of Agricultural SciencesNanjing 210014China College of Light Industry and Food Engineering Nanjing Forestry UniversityNanjing 210037China

In order to effectively deliver lutein to the inflamed colon and better exert its pharmacological activity,this paper constructed a sodium alginate hydrogel-based delivery system loaded with lutein nanoparticles,evaluated the regulation on the expression and secretion of related inflammatory factors in mice with colitis,and its impact on intestinal microbial environment.The results showed that comparing lutein crystal and its nanoparticle,lutein hydrogel alleviated dextran sodium sulfate(DSS)-induced colitis in mice more effectively by adjusting fecal heme content,colon tissue damage,and inflammatory factor levels.Moreover,lutein hydrogel increased the expression of intestinal tight junction proteins zonula occluden-1(ZO-1),claudin-1 and occludin to maintain the integrity of the intestinal-barrier,inhibited the nuclear factor-κB(NF-κB)pathway and reduced expression and secretion of inflammatory factors including tumour necrosis factor-α(TNF-α),inducible nitric oxide synthase(iNOS),NOD-like receptors 3(NLRP3)and interleukin(IL)-1β.In addition,the intestinal microbial environment of mice with colitis was improved by down-regulating the relative abundance of Desulfovibrionaceae and up-regulating the relative abundance of Erysipelotrichaceae and Rikenellaceae.As a slow-release carrier to load lutein nanoparticles,sodium alginate-based hydrogel has potential application prospect.

关键词： Lutein Hydrogel Colitis Intestinal microbiota Inflammation regulation

Comparison on crack propagation under tension at 150℃ of Mg-2Zn-1.5Mn alloy sheets with and without crack notch

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Journal of Magnesium and Alloys 2023年第5期11卷 1536-1548页

作者： Qiang Liu jiangfeng song Qiuyan Shen Liangyin Wu Bin Jiang Weimin Gan Kaihong Zheng Fusheng Pan National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400044China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China GEMS at MLZ Helmholtz-Zentrum HereonGarching D-85748Germany Institute of New Materials Guangdong Academy of SciencesGuangzhou 510650China

Generally,edge crack of rolled magnesium alloy sheets initiates in the RD(rolling direction)-ND(normal direction)plane and then propagate in the RD-TD(transverse direction)plane.Hence,the Mg-2Zn-1.5Mn(ZM21)alloy sheets with and without crack notch were designed to carry out in-situ tensile experiments under 150℃(the same temperature of rolling),with the aim to understand their crack propagation mechanism.The scanning electron microscopy(SEM)and electron backscattered diffraction(EBSD)techniques were utilized to reveal microstructural evolution in real time at designated displacements.The results show that the prismatic slip,basal slip,and extension twining play synergistic role in coordinating strain during the tensile process in ZM21 alloy sheet at 150℃.In both tensile samples with and without crack notch,localized strain is mainly concentrated at relatively fine grain area and the grain boundaries or triple junctions of the grains with large basal Schmid factor(SF)difference,which eventually leads to severe surface roughening and subsequent crack initiation.Compared with the sample without crack notch,the pre-cracked sample exhibits severer deformation at the crack tip due to strain concentration.Strain gradient distribution is observed at the crack tip region in the pre-cracked sample.The crack propagation path of the sample with pre-crack is identified and the underlying mechanism is also discussed.

关键词： ZM21 alloy In-situ tensile test Crack propagation path Crack notch

Development and prospects of degradable magnesium alloys for structural and functional applications in the fields of environment and energy

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Journal of Magnesium and Alloys 2023年第11期11卷 3926-3947页

作者： Yuanding Huang Yaping Zhang jiangfeng song Fusheng Pan Regine Willumeit-Römer Karl Ulrich Kainer Norbert Hort Institute of Metallic Biomaterials Helmholtz-Zentrum hereonMax-Planck-Str.121502 GeesthachtGermany Nano and Heterogeneous Materials Center School of Materials Science and EngineeringNanjing University of Science and TechnologyNanjing210094China National Engineering Research Center for Magnesium Alloys College of Materials Science and EngineeringChongqing UniversityChongqing 400044PR China Chair of Light Elements Engineering Foundry and AutomationWrocław University of Science and Technology50-370 WrocławW.Wyspianskiego 27Poland Institute of Product&Process Innovation Leuphana University LüneburgUniversitätsallee 121335 LüneburgGermany

Magnesium and its alloys have such advantages with lightweight, high specific strength, good damping, high castability and machinability,which make them an attractive choice for applications where weight reduction is important, such as in the aerospace and automotive industries.However, their practical applications are still limited because of their poor corrosion resistance, low high temperature strength and ambient formability. Based on such their property shortcomings, recently degradable magnesium alloys were developed for broadening their potential applications. Considering the degradable Mg alloys for medical applications were well reviewed, the present review put an emphasis on such degradable magnesium alloys for structural and functional applications, especially the applications in the environmental and energy fields. Their applications as fracture ball in fossil energy, sacrificial anode, washing ball, and as battery anodes, transient electronics, were summarized. The roles of alloying elements in magnesium and the design concept of such degradable magnesium alloys were discussed. The existing challenges for extending their future applications are explored.

关键词： Magnesium alloys Alloying Structural applications Degradation Mechanical property Corrosion property Fossil and hydrogen energy Fracture ball Battery anode Transient electronics Hydrogen energy