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Potential Hazards in Smoke-Flavored Fish

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Journal of Ocean University of China 2008年第3期7卷 294-298页

作者： liN hong jiang Jie li Donghua Seafood Safety Lab College of Food Science and Engineering Ocean University of China Qingdao 266003 P. R. China

Smoking is widely used in fish processing for the color and flavor. Smoke flavorings have evolved as a successful alternative to traditional smoking. The hazards of the fish products treated by liquid-smoking process are discussed in this review. The smoke flavoring is one important ingredient in the smoke-flavored fish. This paper gives the definition of smoke flavorings and the hazard of polycyclic aromatic hydrocarbons （PAHs） residue in the smoke flavorings on the market. It gives also an assessment of chemical hazards such as carcinogenic PAHs, especially Benzo-[α]pyrene, as well as biological hazards such as listeria monocytogenes, Clostridium botulinum, histamine and parasites in smoke-flavored fish. The limitations in regulations or standards are discussed. Smoke flavored fish have lower content of PAHs as compared with the traditional smoking techniques if the PAHs residue in smoke flavorings is controlled by regulations or standards.

关键词： smoke-flavored fish hazards smoke flavoring PAHs

Analysis of Graves＇ ophthalmopathy patients＇ tear protein spectrum

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Chinese Medical Journal 2013年第23期126卷 4493-4498页

作者： jiang li-hong WEI Rui-li Department of Ophthalmology Shanghai Changzheng Hospital Affiliated to Shanghai Second Military Medical University Shanghai 200003 China

Background Graves＇ ophthalmopathy/orbitopathy （GO） patients often suffer ocular surface damages and tear fluid proteins play a significant role in maintaining healthy ocular surfaces,while changes in tear protein components reflect the changes ocular surface *** this study proteomics techniques were used to investigate tear protein compositions in GO *** We carried out a case-control study by comparing tear fluid contents of GO patients with that of healthy *** the first step the tears were subjected to SDS-PAGE electrophoresis and then single protein bands were analyzed by to in-gel trypsin digestion and nano-flow liquid mass spectrometry （LC-MS/MS） using a MS *** In tear samples of GO subjects,the protein fractions of inflammation-related protein immunoglobulin kappa chain C region （IgKC） and serum albumin were essentially reduced,whereas a novel isoform of complement component 3 （C3）,which we detected in control subjects,was completely absent in the GO patients＇ *** Reduced protein concentrations of particularly IgKC and complement C3 as well as albumin in the tears of GO patients may contribute to changes in their ocular surfaces via diminished reactive oxygen species （ROS） depletion and adaptive immune *** completely absent of C3 in the GO patients＇ tears,may imply that an important inflammatory signaling pathway is affected,which needs further investigation.

关键词： Graves' ophthalmopathy tears protein spectrum serum albumin complement C3

Transcriptional identification of differentially expressed genes associated with division of labor in Apis cerana cerana

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Insect Science 2021年第2期28卷 457-471页

作者： Yi-Jie Chen Ying-Jiao li Shuang Wu Wen-Chao Yang Jing Miao Shao-Hua Gu jiang-hong li Xiao-Qing Miao Xianchun li College of Bee Science Fujian Agriculture and Forestry UniversityFuzhouChina State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijingChina Department of Entomology and BI05 Institute University of ArizonaTucsonAZUSA

Workers of Apis cerana cerana undergo an in-hive nursing to outdoor foraging transition,but the genes underlying this age-related transition remain largely ***,we sequenced the head transcriptomes of its 7-day-old normal nurses,18-and 22-day-old normal foragers,7-day-old precocious foragers and 22-day-old over-aged nurses to unravel the genes associated with this *** of the sequence reads to Apis mellifera genome showed that the three types of foragers had a greater percentage of reads from annotated exons and intergenic regions,whereas the two types of nurses had a greater percentage of reads from ***-and group-wise comparisons of the five transcriptomes revealed 59 uniquely expressed genes(18 in nurses and 41 in foragers)and 14 nurse-and 15 forager-upregulated *** uniquely expressed genes are usually low-abundance long noncoding RNAs,transcription factors,transcription coactivators,RNA-binding proteins,kinases or phosphatases that are involved in signaling and/or regulation,whereas the nurse-or forager-upregulated genes are often high-abundance downstream genes that directly perform the tasks of nurses or *** together,these results suggest that the nurse-forager transition is coordinated by a social signal-triggered epigenetic shift from introns to exons/intergenic regions and the resulting transcriptional shift between the nurse-and forager-associated genes.

关键词： behavioral transition epigenetic shift IncRNA over-aged nurses precocious foragers signaling genes

Effect of recombinant human endostatin on endometriosis in mice

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Chinese Medical Journal 2007年第14期120卷 1241-1246页

作者： jiang hong-qing li Ya-li ZOU Jie Department of Obstetrics and Gynecology General Hospital of the People＇s Liberation Army Beijing 100853 China

Background Direct and indirect evidences have suggested that angiogenesis is a prerequisite for the development of endometriosis. Aiming at offering experimental evidences for anti-angiogenesis therapy, we transplanted the eutopic endometrium from patient with endometriosis into the severe combined immunodeficiency disease （SCID） mice, to evaluate the effect of the endostatin on the growth and angiogenesis of the established endometriosis lesions in SCID mice model. Methods Eutopic endometrium of women with endometriosis was transplanted into the SCID mice. The mice were randomized into treatment （n= 10） and control groups （n=10）. Two weeks after the implantation of endometrium fragment, the treatment group was injected with recombinant human endostatin YH-16 into the peritoneal cavity （2 mg·kg^-1·d^-1）, whereas the control group received equivalent volume of PBS （200 μl/d）. The volume of endometriotic lesions in SCID mice was measured every three days, and all the treatment lasted for 14 days. Immunohistochemistry was used to determine microvessel density （MVD） and the expression of VEGF. The results were analyzed by t test and X^2 test to value the treating effect. Results Compared with the control group, growth of endometriosis lesion was reduced in the mice treated with YH-16. Statistically significant differences in the volume and weight of the ectopic lesions were observed between the treatment and the control groups （P〈0.05）. Microscopical examination showed that after being treated with YH-16, the volume of the endometrial tissues decreased, the glands depauperated, and the glandular epithelium partially degenerated. Necrotic debris was observed in the endometrial stroma. MVD and expression of VEGF in the treatment group were significantly lower than those in the control group （P〈0.05）.Conclusions Recombinant human endostatin affects the maintenance and growth of endometriotic tissues by inhibiting angiogenesis and reducing the expression of VEGF in ec

关键词： endometriosis recombinant human endostatin animal model

Photochemical properties of hypocrellin A,B and their oxides

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Chinese Journal of Chemistry 1990年第1期8卷 55-60页

作者： ZHAO,Kai-hong jiang,li-Jin Institute of Photographic Chemistry,Academia Sinica,Beijing 100012 Institute of Photographic Chemistry Academia Sinica Beijing 100012

Hypocrellin A and B in methanol were autosensitized and photooxygenated to 1,4,6, 7 and 2,5,8,9 respectively.1 in methanol was photooxygenated to 6 and 7 under the sensitization by HB.1 in methanol was photooxygenated to 7 under the sensitization by Rose bengal.1 in benzene ir- radiated with medium-pressure-mercury lamp was photolyzed to 3 in the presence of iodine.

关键词： HB Photochemical properties of hypocrellin A,B and their oxides

界面相容剂对PE-HD/木粉复合材料力学性能的影响

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高分子材料科学与工程 2005年第2期21卷 204-207页

作者：姜洪丽李斌东北林业大学理学院化学化工系黑龙江哈尔滨150040

用不同的界面相容剂对高密度聚乙烯(PE-HD)/木粉复合材料进行界面处理,研究了界面相容剂的含量、种类对复合体系力学性能的影响。结果表明,界面相容剂的加入使复合体系的力学性能有不同程度的改善,其中MAPE的加入,对体系的拉伸、弯曲强... 详细信息

用不同的界面相容剂对高密度聚乙烯(PE-HD)/木粉复合材料进行界面处理,研究了界面相容剂的含量、种类对复合体系力学性能的影响。结果表明,界面相容剂的加入使复合体系的力学性能有不同程度的改善,其中MAPE的加入,对体系的拉伸、弯曲强度提高最大,在MAPE含量为10%时,复合体系的力学性能达到最大值;经EPDM-MA处理的复合材料,其冲击韧性有明显提高;EVA-MA的加入,使复合材料的性能有所提高;SBS对体系界面粘接力的影响不明显;但MAPE和弹性体SBS复配处理的复合体系,其冲击强度的提高尤为显著,这可能是由于MAPE和SBS在复合体系中发生了协效作用,形成具有柔韧性的中间相所致。

关键词：高密度聚乙烯木粉复合材料界面相容剂力学性能协效作用

Metronomic capecitabine inhibits liver transplant rejection in rats by triggering recipients’T cell ferroptosis

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World Journal of Gastroenterology 2023年第20期29卷 3084-3102页

作者： Hao Wang Zheng-Lu Wang Sai Zhang De-Jun Kong Rui-Ning Yang Lei Cao Jian-Xi Wang Sei Yoshida Zhuo-Lun Song Tao liu Shun-li Fan Jia-Shu Ren jiang-hong li Zhong-Yang Shen hong Zheng The First Central Clinical School Tianjin Medical UniversityTianjin 300190China Department of Organ Transplant Tianjin First Central HospitalSchool of MedicineNankai UniversityTianjin 300190China Key Laboratory of Transplant Medicine Chinese Academy of Medical SciencesTianjin 300190China School of Medicine Nankai UniversityTianjin 300190China Research Institute of Transplant Medicine Nankai UniversityTianjin 300071China Tianjin Key Laboratory for Organ Transplantation Tianjin First Central HospitalSchool of MedicineNankai UniversityTianjin 300071China National Health Commission’s Key Laboratory for Critical Care Medicine Tianjin First Central HospitalTianjin 300071China

BACKGROUND Capecitabine(CAP)is a classic antimetabolic drug and has shown potential antirejection effects after liver transplantation(LT)in clinical *** previous study showed that metronomic CAP can cause the programmed death of T cells by inducing oxidative stress in healthy ***,a newly defined non-apoptotic cell death that occurs in response to iron overload and lethal levels of lipid peroxidation,is an important mechanism by which CAP induces cell ***,ferroptosis may also play an important role in CAP-induced T cell death and play an immunosuppressive role in acute rejection after *** To investigate the functions and underlying mechanisms of antirejection effects of metronomic *** A rat LT model of acute rejection was established,and the effect of metronomic CAP on splenic hematopoietic function and acute graft rejection was evaluated 7 d after *** vitro,primary CD3+T cells were sorted from rat spleens and human peripheral blood,and co-cultured with or without 5-fluorouracil(5-FU)(active agent of CAP).The levels of ferroptosis-related proteins,ferrous ion concentration,and oxidative stress-related indicators were *** changes in mitochondrial structure were observed using electron *** With no significant myelotoxicity,metronomic CAP alleviated graft injury(Banff score 9 vs 7.333,Pliver graft(7.459 vs 3.432,Plism,induced the degradation of the ferritin heavy chain by upregulating nuclear receptor coactivator 4,which caused the accumulation of ferrous *** also inhibited nuclear erythroid 2 p45-related factor 2,heme oxygenase-1,and glutathione peroxidase 4,eventually leading to oxidati

关键词： Capecitabine Ferroptosis T Lymphocytes Immunosuppressive agents Graft rejection liver transplantation

基于线性收缩的大阵列MIMO雷达目标盲检测

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吉林大学学报（工学版） 2017年第3期47卷 973-980页

作者：姜宏李垠吕巍吉林大学通信工程学院长春130012

针对阵元数与快拍数可以相比拟的大阵列MIMO雷达系统,将协方差矩阵估计的收缩算法与大维随机矩阵理论相结合,提出了一种基于线性收缩-标准条件数(LS-SCN)的目标盲检测新方法。通过求解大维系统样本协方差矩阵的优化矩阵,并利用M-P律,推... 详细信息

针对阵元数与快拍数可以相比拟的大阵列MIMO雷达系统,将协方差矩阵估计的收缩算法与大维随机矩阵理论相结合,提出了一种基于线性收缩-标准条件数(LS-SCN)的目标盲检测新方法。通过求解大维系统样本协方差矩阵的优化矩阵,并利用M-P律,推导了检测阈值与收缩系数之间的关系,分别给出了基于LS-SCN的单目标和多目标检测算法。该方法无需已知噪声方差、目标散射矩阵和目标方位等先验信息,对噪声变化不敏感,且适用于大阵列系统。仿真结果表明,在阵元数与快拍数在同一数量级的情况下,与SCN算法和MDL算法相比,显著提高了目标检测性能。

关键词：通信技术雷达工程目标检测大维随机矩阵理论收缩算法大阵列

Exploration of the Facilitative Effects of Music Acquiring Device on Language Acquisition

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Sino-US English Teaching 2014年第2期11卷 119-128页

作者： liU Yu-sha jiang Yu-hong li Fei Southwest University Chongqing China

Music Acquiring Device （or MAD, for short） is proposed to identify the origin and acquisition of human language, and is regarded as preceded Chomsky＇s LAD （Language Acquisition Device）. This paper tries to find the answers to two questions. Firstly, what are the main similarities between music and language？ Secondly, in what aspects can music facilitate language similarities （sound, rhythm, and acquisiti structure on？ By literature reviewing, comparison and contrast, three main ） between music and language are discussed, and then three facilitative effects of MAD on language acquisition are illustrated. They are：（1） MAD lays a foundation for language pronunciation acquisition; （2） MAD accelerates the mastery of language rhythm; and （3） MAD promotes language syntax acquisition. This paper will help teachers who like to use music-assistant language teaching method understand more about the positive effects of music on language teaching and acquisition.

关键词： language and music language acquisition MAD (Music Acquiring Device) facilitative effect