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World Journal of Gastrointestinal Oncology 2021年第12期13卷 2190-2202页

作者： jiang-min zhou Chen-Yang zhou Xiao-Ping Chen Zhi-Wei Zhang Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina Translational Medicine Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina

BACKGROUND The long-term effect of anatomic resection(AR)is better than that of nonanatomic resection(NAR).At present,there is no study on microvascular invasion(MVI)and liver resection *** To explore whether AR improves long-term survival in patients with hepatocellular carcinoma(HCC)by removing the peritumoral *** A total of 217 patients diagnosed with HCC were enrolled in the *** surgical margin was routinely *** to the stratification of different tumor diameters,patients were divided into the following groups:≤2 cm group,2-5 cm group,and>5 cm *** In the 2-5 cm diameter group,the overall survival(OS)of MVI positive patients was significantly better than that of MVI negative patients(P=0.031).For the MVI positive patients,there was a statistically significant difference between AR and NAR(P=0.027).AR leads to a wider surgical margin than NAR(2.0±2.3 cm vs 0.7±0.5 cm,P5 cm,both AR and NAR fail to obtain wide surgical margin(0.6±1.0 cm vs 0.7±0.4 cm,P=0.491).CONCLUSION For patients with a tumor diameter of 2-5 cm,AR can achieve the removal of peritumoral MVI by obtaining a wide incision margin,reduce postoperative recurrence,and improve prognosis.

关键词： Microvascular invasion Hepatocellular carcinoma Anatomic resection Surgical margin Recurrence Surgery

Correlation between immune-related adverse events and long-term outcomes in pembrolizumab-treated patients with unresectable hepatocellular carcinoma:A retrospective study

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World Journal of Gastrointestinal Oncology 2023年第4期15卷 689-699页

作者： jiang-min zhou Hui-Fang Xiong Xiao-Ping Chen Zhi-Wei Zhang Li-Ping Zhu Biao Wu Department of Hepatobiliary Surgery Wuhan Hospital of Traditional Chinese and Western MedicineWuhan 430030Hubei ProvinceChina Department of Digestive Medicine Dongxihu District People’s HospitalWuhan 430030Hubei ProvinceChina Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina

BACKGROUND Although immune checkpoint inhibitor(ICI)therapy has improved the prognosis of unresectable hepatocellular carcinoma(HCC),it has also resulted in unique immune-related adverse events(irAEs).The relationship between irAE and treatment outcomes in ICI-treated unresectable HCC patients remains *** To elucidate the correlation between immune-related toxic effects and prognosis in patients with unresectable HCC treated with *** From March 2019 to February 2021,a total of 190 unresectable HCC(Barcelona Clinic Liver Cancer C)patients receiving pembrolizumab treatment were retrospectively *** survival(OS)was the primary endpoint,while objective response rate(ORR),disease control rate(DCR),and time to progression(TTP)were secondary evaluation *** assessed demographics,irAEs,and outcomes by retrospective *** One hundred and forty-three males and 47 females were included in the *** ORR and DCR were 12.1%(23/190)and 52.1%(99/190),*** median OS was 376 d[95%confidence interval(CI):340-411 d]and the median TTP was 98 d(95%CI:75-124 d).The overall incidence of treatment-related adverse events was 72.6%(138/190)and 10.0%of them were severe irAEs(grade≥3).Child-Pugh B class,portal vein tumor thrombus,extrahepatic metastasis,and hypothyroidism were the independent risk factors for *** with hypothyroidism showed a longer OS[517 d(95%CI:423-562)vs 431 d(95%CI:412-485),P=0.011]and TTP[125 d(95%CI:89-154)vs 87 d(95%CI:61-98),P=0.004]than those without *** Pembrolizumab-treated patients with unresectable HCC who experienced hypothyroidism have promising ORR and durable ***,an irAE,may be used as a clinical evaluation parameter of response to ICIs in unresectable HCC.

关键词： Hepatocellular carcinoma Immune checkpoint inhibitors Pembrolizumab Immune-related adverse events Overall survival Retrospective study

Deterministic Teleportation in a Switch Network via Probabilistic Channels

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Deterministic Teleportation in a Switch Network via Probabil...

多尺度卷积递归神经网络的RGB-D物体识别

第三十届中国控制会议

作者： jiang min,HUANG Xu,zhou mintong School of Electronics & Information Engineering,Soochow University,Suzhou 215021,P.R.China

＜正＞We present a systematic scheme for deterministic teleportation in a quantum switch network based on probabilistic communication *** this scheme,the burden of terminal agents originally caused by the introduction of auxiliary qubits and the operations of high dimensional unitary gates could be *** such a way,our scheme will bring great convenience to realize deterministic teleportation in quantum probabilistic network for the present purpose.

关键词： Deterministic Teleportation Probabilistic Channel Quantum Network High Dimensional Gates

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计算机应用研究 2017年第9期34卷 2834-2837,2870页

作者：骆健蒋旻刘星周龙武汉科技大学计算机科学与技术学院智能信息处理与实时工业系统湖北省重点实验室武汉430065

为充分利用RGB-D图像提供的潜在特征信息,提出了多尺度卷积递归神经网络算法(multi-scale convolutional-recursive neural networks,Ms-CRNN)。该算法对RGB-D图像的RGB图、灰度图、深度图及3D曲面法线图进行不同尺度分块形成多个通道,... 详细信息

为充分利用RGB-D图像提供的潜在特征信息,提出了多尺度卷积递归神经网络算法(multi-scale convolutional-recursive neural networks,Ms-CRNN)。该算法对RGB-D图像的RGB图、灰度图、深度图及3D曲面法线图进行不同尺度分块形成多个通道,每个通道与相应尺寸的滤波器卷积,提取的特征图经局部对比度标准化和下采样后,作为递归神经网络(recursive neural networks,RNN)层的输入以得到更加抽象的高层特征;融合后的多尺度特征由SVM分类器进行分类。基于RGB-D数据集的仿真实验结果表明,综合利用RGB-D图像的多尺度特征,提出的Ms-CRNN算法在物体识别率上达到88.2%,与先前方法相比有了较大的提高。

关键词：多尺度 3D曲面法线递归神经网络 RGB—D物体识别

Quantum Switching Limited by Nearest-Neighboring Coupling

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Quantum Switching Limited by Nearest-Neighboring Coupling

内服活络效灵丹联合肩关节镜下松解术治疗冻结肩临床观察

第二十九届中国控制会议

作者： jiang min1,zhou Yiming2,WAN min3 1 School of Electronics&Information Engineering,Soochow University,Suzhou 215021,P.R.China2 China academy of space technology,Beijing 100094,P.R.China3 Department of engineering,Zhenjiang watercraft college,Zhenjiang 212003,P.R.China

In this paper,we propose a quantum switching architecture under the nearest coupling *** order to reduce implementation time steps,an efficient quantum shear sorting（QSS）algorithm is *** use of QSS algorithm,the running complexity of the improved quantum switching architecture is polynomial time even under nearest coupling interaction and the implementation complexity is *** improved switching is extremely simple to implement by existing quantum computer candidates.

关键词： Quantum Switching Nearest-neighboring Coupling Quantum Sorting Circuit

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中国中医药现代远程教育 2025年第2期23卷 86-89页

作者：彭健江文勇周敏江西省泰和县中医院骨科江西吉安343700

目的探究内服活络效灵丹联合肩关节镜下松解术治疗冻结肩的临床效果。方法选取2017年7月—2022年11月江西省泰和县中医院骨科收治的46例冻结肩患者,随机分为研究组和对照组,各23例。研究组采取内服活络效灵丹联合肩关节镜下松解术治疗,... 详细信息

目的探究内服活络效灵丹联合肩关节镜下松解术治疗冻结肩的临床效果。方法选取2017年7月—2022年11月江西省泰和县中医院骨科收治的46例冻结肩患者,随机分为研究组和对照组,各23例。研究组采取内服活络效灵丹联合肩关节镜下松解术治疗,对照组采取单纯的肩关节镜下松解术治疗,并进行为期6个月的随访。比较两组治疗前后视觉模拟量表(VAS)、加州大学肩关节评分系统(UCLA)评分、美国肩肘外科医师协会(ASES)评分、Constant-Murley评分与肩关节活动度差异,评价两组患者肩关节活动功能;观察治疗后6个月内患者冻结肩康复情况。结果研究组VAS评分显著低于对照组(P<0.05);研究组UCLA评分、ASES评分、Constant-Murley评分显著高于对照组(P<0.05);研究组肩关节活动程度显著高于对照组(P<0.05)。结论内服活络效灵丹联合肩关节镜下松解术在冻结肩治疗中能取得优良的效果,手术以微创为主,以其创伤小、住院周期短、恢复快的特点使得患者容易接受,再结合中药活络效灵丹内服可起到治病求本的作用,中西医结合,标本兼治,在临床中是值得大范围推崇的一种行之有效的方案,能够解决冻结肩患者肩关节疼痛伴活动受限带来的苦恼。

关键词：肩凝冻结肩活络效灵丹关节镜中西医结合疗法

Variable Selection for Distributed Sparse Regression Under Memory Constraints

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Communications in Mathematics and Statistics 2024年第2期12卷 307-338页

作者： Haofeng Wang Xuejun jiang min zhou Jiancheng jiang Department of Mathematics Harbin Institute of TechnologyHarbinPeople's Republic of China Department of Statistics and Data Science Southerm Univerity of Science and TechnologyShenzhenPeople's Republic of China Beijing Normal University-Hong Kong Baptist University United International College ZhuhaiPeople's Republic of China Department of Mathematics and Statistics University of North Carolina at CharlotteCharlotteUSA

This paper studies variable selection using the penalized likelihood method for dis-tributed sparse regression with large sample size n under a limited memory *** is a much needed research problem to be solved in the big data era.A naive divide-and-conquer method solving this problem is to split the whole data into N parts and run each part on one of N machines,aggregate the results from all machines via averaging,andﬁnally obtain the selected ***,it tends to select more noise variables,and the false discovery rate may not be well *** improve it by a special designed weighted average in *** the alternating direction method of multiplier can be used to deal with massive data in the literature,our proposed method reduces the computational burden a lot and performs better by mean square error in most ***,we establish asymptotic properties of the resulting estimators for the likelihood models with a diverging number of *** some regularity conditions,we establish oracle properties in the sense that our distributed estimator shares the same asymptotic efﬁciency as the estimator based on the full ***,a distributed penalized likelihood algorithm is proposed to reﬁne the results in the context of general ***,the proposed method is evaluated by simulations and a real example.

关键词： Variable selection Distributed sparse regression Memory constraints Distributed penalized likelihood algorithm

Cu-Based Materials for Enhanced C_(2+) Product Selectivity in Photo-/Electro-Catalytic CO_(2) Reduction: Challenges and Prospects

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Nano-Micro Letters 2024年第4期16卷 25-66页

作者： Baker Rhimi min zhou Zaoxue Yan Xiaoyan Cai Zhifeng jiang Institute for Energy Research School of Chemistry and Chemical EngineeringJiangsu UniversityZhenjiang 212013People’s Republic of China School of Materials Science and Physics China University of Mining and TechnologyXuzhou 221116People’s Republic of China

Carbon dioxide conversion into valuable products using photocatalysis and electrocatalysis is an effective approach to mitigate global environmental issues and the energy shortages. Among the materials utilized for catalytic reduction of CO_(2), Cu-based materials are highly advantageous owing to their widespread availability, cost-effectiveness, and environmental sustainability. Furthermore, Cu-based materials demonstrate interesting abilities in the adsorption and activation of carbon dioxide, allowing the formation of C_(2+) compounds through C–C coupling process. Herein, the basic principles of photocatalytic CO_(2) reduction reactions(PCO_(2)RR) and electrocatalytic CO_(2) reduction reaction(ECO_(2)RR) and the pathways for the generation C_(2+) products are introduced. This review categorizes Cu-based materials into different groups including Cu metal, Cu oxides, Cu alloys, and Cu SACs, Cu heterojunctions based on their catalytic applications. The relationship between the Cu surfaces and their efficiency in both PCO_(2)RR and ECO_(2)RR is emphasized. Through a review of recent studies on PCO_(2)RR and ECO_(2)RR using Cu-based catalysts, the focus is on understanding the underlying reasons for the enhanced selectivity toward C_(2+) products. Finally, the opportunities and challenges associated with Cu-based materials in the CO_(2) catalytic reduction applications are presented, along with research directions that can guide for the design of highly active and selective Cu-based materials for CO_(2) reduction processes in the future.

关键词： Photocatalytic CO_(2)reduction Cu-based materials Electrocatalytic CO_(2)reduction

Synergistic Effect of Dual-Doped Carbon on MO_(2)C Nanocrystals Facilitates Alkaline Hydrogen Evolution

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Nano-Micro Letters 2023年第10期15卷 101-111页

作者： min zhou Xiaoli jiang Weijie Kong Hangfei Li Fei Lu Xin zhou Yagang Zhang School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of ChinaChengdu 610054People’s Republic of China College of Physical Science and Technology Yangzhou UniversityYangzhou 225002People’s Republic of China Department of Chemical Engineering Polytechnique MontrealMontrealQC H3C 3A7Canada

Molybdenum carbide(MO_(2)C)materials are promising electrocatalysts with potential applications in hydrogen evolution reaction(HER)due to low cost and Pt-like electronic ***,their HER activity is usually hindered by the strong hydrogen binding ***,the lack of water-cleaving site's makes it difficult for the catalysts to work in alkaline ***,we designed and synthesized a B and N dual-doped carbon layer that encapsulated on MO_(2)C nanocrystals(MO_(2)C@BNC)for accelerating HER under alkaline *** electronic interactions between the MO_(2)C nanocrystals and the multiple-doped carbon layer endow a near-zero H adsorption Gibbs free energy on the defective C atoms over the carbon ***,the introduced B atoms afford optimal H_2O adsorption sites for the water-cleaving ***,the dual-doped MO_(2)C catalyst with synergistic effect of non-metal sites delivers superior HER performances of a low overpotential(99 mV@10 mA cm^(-2))and a small Tafel slope(58.1 mV dec^(-1))in 1 M KOH ***,it presents a remarkable activity that outperforming the commercial 10%Pt/C catalyst at large current density,demonstrating its applicability in industrial water *** study provides a reasonable design strategy towards noble-metal-free HER catalysts with high activity.

关键词： Molybdenum carbide Hydrogen evolution reaction Dual-doped Synergistic effect Superior performances

A new triterpenoid from the roots of Tripterygium wilfordii

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Chinese Chemical Letters 2010年第5期21卷 600-602页

作者： Lin Mei zhou jiang Du Chun min Wu Fujian Institute for Drug Control Fuzhou 350001China Kunming Biovalley Material Medical Research Institute Kunming 650224China

A new triterpenoid 3,4,6-trihydroxy-2-oxo-1(10),3,5,7-tetraen-23,24-nor-D:A-friedooleana-29-oic acid,as well as twelve known terpenes were isolated from the roots of Tripterygium *** structure was established on the b... 详细信息

关键词： Tripterygium wilfordii Chemical constituents Triterpene