检索结果-南通市图书馆

Synthesis of highly stable Ni nanoparticles via electrostatic self-assembly for enhanced hydrogen storage of MgH_(2)

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第9期43卷 4356-4366页

作者： Qin-Ke Tang jiang-chuan liu Rui Shi Yun-Feng Zhu Ji-Guang Zhang Ya-Na liu Jun Wang Yao Zhang Xiao-Hui Hu Zhi-Bin liu Li-Quan Li College of Materials Science and Engineering Jiangsu Collaborative Innovation Centre for Advanced Inorganic Function CompositesNanjing Tech UniversityNanjing 211816China School of Materials Science and Engineering Southeast UniversityNanjing 211189China

Magnesium-based hydrides have been widely recognized as an appropriate choice for solid-state hydrogen ***,its undesirable thermodynamics and sluggish hydrogenation/dehydrogenation kinetics are major bottlenecks for its ***,a highly stable and highly dispersed Ni-based catalyst(Ni/Al_(2)O_(3)/GN)was fabricated to promote the hydrogen storage performance of MgH_(2)via the electrostatic effect of NiAl-LDH/GN precursor with a co-calcination reduction ***_(2)-5wt%Ni/Al_(2)O_(3)/GN exhibits excellent hydrogen storage performance,releasing about 5.7 wt%hydrogen in 3500 s at 250℃,and can reach a saturation hydrogen absorption of about 6.15 wt%in 3000 s at 100℃.Furthermore,it also shows low dehydrogenation apparent activation energy of 89.1 and 118.2 kJ·mol^(-1).Impressively,the catalyst ensures the stability of both the physical phase and structure during ball milling and cycling *** role of each phase in Ni/Al_(2)O_(3)/GN on the hydrogen storage performance of MgH_(2)was also discussed through experiments and theoretical calculation,and the synergistic catalytic mechanism of Ni/Al_(2)O_(3)/GN was clearly *** work provides a unique perspective for the preparation of highly stable and highly dispersible catalysts.

关键词： Magnesium hydride Ni/Al_(2)O_(3)/GN Hydrogen storage performance Catalytic mechanism

miR-29a up-regulation in AR42J cells contributes to apoptosis via targeting TNFRSF1A gene

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2016年第20期22卷 4881-4890页

作者： Qiang Fu Tao Qin Lin Chen chuan-jiang liu Xu Zhang Yu-Zhu Wang Ming-Xing Hu Hao-Yuan Chu Hong-Wei Zhang Department of Hepatobiliary Pancreatic Surgery People’s Hospital of Zhengzhou University School of Medicine Zhengzhou University

AIM: To investigate the expression of mi R-29 a in rat acute pancreatitis and its functional role in AR42 J cell ***: Twelve SD rats were divided into a control group and an acute edematous pancreatitis(AEP) group randomly. AEP was induced by intraperitoneal injection of L-arginine(150 mg/kg) in the AEP group and equal volume of 0.9% Na Cl was injected in the control group. The apoptosis of acinar cells in pancreatic tissue was determined by TUNEL assay. mi RNA chip assay was performed to examine the expression of mi RNAs in two groups. Besides, to further explore the role of mi R-29 a in apoptosis in vitro, recombinant rat TNF-α(50 ng/m L) was administered to treat the rat pancreatic acinar cell line AR42 J for inducing AR42 J cell apoptosis. Quantitative real-time PCR(q RT-PCR) was adopted to measure mi R-29 a expression. Then, mi RNA mimic, mi RNA antisense oligonucleotide(AMO) and control vector were used to transfect AR42 J cells. The expression of mi R-29 a was confirmed by q RT-PCR andthe apoptosis rate of AR42 J cells was detected by flow cytometry analysis. Western blot was used to detect the expression of activated caspase3. Moreover, we used bioinformatics software and luciferase assay to test whether TNFRSF1 A was the target gene of mi R-29 a. After transfection, q RT-PCR and Western blot was used to detect the expression of TNFRSF1 A in AR42 J cells after ***: The expression of mi R-29 a was much higher in the AEP group compared with the control group as displayed by the mi RNA chip assay. After inducing apoptosis of AR42 J cells in vitro, the expression of mi R-29 a was significantly increased by 1.49 ± 0.04 times in comparison with the control group. As revealed by q RT-PCR assay, the expression of mi R-29 a was 2.68 ± 0.56 times higher in the mi R-29 a mimic group relative to the control vector group, accompanied with an obviously increased acinar cell apoptosis rate(42.83 ± 1.25 vs 24.97 ± 0.15, P < 0.05). Moreover, th

关键词： Acute edematous pancreatitis mi R-29a Apoptosis AR42J Target gene TNFRSF1A

Glucocorticoid receptor regulates expression of microRNA-22 and downstream signaling pathway in apoptosis of pancreatic acinar cells

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2018年第45期24卷 5120-5130页

作者： Qiang Fu chuan-jiang liu Xu Zhang Zhen-Sheng Zhai Yu-Zhu Wang Ming-Xing Hu Xian-Ling Xu Hong-Wei Zhang Tao Qin Department of Hepatobiliary and Pancreatic Surgery People’s Hospital of Zhengzhou University (Henan Provincial People’s Hospital) School of Medicine Zhengzhou University

AIM To elucidate the underlying mechanism that microRNA-22(miR-22) promotes the apoptosis of rat pancreatic acinar cells(AR42 J) and the elements that regulate the expression of *** One hundred nanomoles per liter of caerulein(Cae)was administrated to induce the apoptosis of AR42 J cells and the apoptosis rate was detected by flow cytometry analysis. An amylase assay kit was used to measure the amylase expression level in the supernatant. Quantitative real-time PCR(qRT-PCR)was adopted to measure miR-22 expression. We used online tools to predict the potential transcription promoter of miR-22 and the binding sites, which was further identified by using luciferase reporter analysis,chromatin immunoprecipitation(ChIP) and ChIPqP CR assays. Then, a mimic of miR-22, Nr3 c1 plasmid encoding the glucocorticoid receptor(GR), and siNr3 c1 were used to transfect AR42 J cells, *** mRNA expression of miR-22, Nr3 c1, and Erb-b2 receptor tyrosine kinase 3(ErbB3) was confirmed by qRT-PCR and the apoptosis rate of AR42 J cells was detected by flow cytometry analysis. Western blot was used to detect the expression of ErbB3, GR, PI3 k, PI3 kp85α, Akt, p-Akt, Bad, Bax, Bcl-xl, Bcl-2, and cleaved *** After inducing apoptosis of AR42 J cells in vitro, the expression of miR-22 was significantly increased by2.20 ± 0.26 and 4.19 ± 0.54 times, respectively, at3 h and 6 h in comparison with the control *** revealed by qRT-PCR assay, the expression of miR-22 was 78.25 ± 6.61 times higher in the miR-22 mimic group relative to the miRNA control group,accompanied with an obviously increased acinar cell apoptosis rate(32.53 ± 1.15 vs 18.07 ± 0.89, P =0.0006). The upregulation of miR-22 could suppress its target gene, ErbB3, and the phosphorylation of PI3 k and Akt. Furthermore, we predicted the potential transcription promoter of miR-22 and the binding sites using online tools. Luciferase reporter analysis and sitedirected mutagenesis indicated that the b

关键词： MicroRNA-22 Apoptosis Pancreatic acinar cells Erb-b2 receptor tyrosine kinase 3 Glucocorticoid receptor

Traditional Chinese Medicine Based on Zheng Differentiation versus Angiotensin Receptor Blocker/Angiotensin?converting Enzyme Antagonist in Efficacy of Treating Diabetic Kidney Disease: A Meta?analysis of Randomized Clinical Trials

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Traditional Chinese Medicine 2019年第1期5卷 18-28页

作者： Wei-Jun Huang Tao Yang chuan-jiang liu Yong-Hua Xiao Qiang Fu Qing Gong Hua Zhang Fan Shao Hong Yue Shi-Dong Wang Jin-Xi Zhao Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing Second Department of Endocrinology and Nephropathy Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

Objective: To compare the efficacy of traditional Chinese medicine(TCM) based on Zheng differentiation with angiotensin receptor blocker/angiotensin-converting enzyme inhibitor(ARB/ACEI) in treating diabetic kidney disease(DKD) from the aspects of decreasing urinary microalbumin, declining 24-h urinary protein, reducing endpoint events, and renal function protection. Methods: The Chinese Biomedical Literature Database(CBM), the Chinese Academy of Sciences database(CNKI), the VIP Chinese journal database, Wanfang DATA, Medline database, Cochrane library, excerpt medical database(Embase), and Web of science were used for literature searching. The reviewer manager5.3 software was utilized to analyze the data. Results: Twenty-four studies including 1956 participants were involved in this review. Results showed that TCM had a better effect(mean difference [MD],-23.20, 95% confidence interval [CI],-30.60 to-15.79, P 24 weeks) subgroup. TCM worked as well as ACEI/ARB in reducing endpoint events(relative risk, 0.67, 95% CI, 0.20–2.224, P = 0.51)and decreasing urinary albumin concentration(UAC)(MD,-16.50, 95% CI,-46.28–13.28, P = 0.28). As for protecting renal function, TCM had an equal effect to AECI/ARB in improving creatinine clearance ratio(MD,-3.30, 95% CI,-6.66–0.03, P = 0.05) or estimated glomerular filtration rate(MD, 1.00, 95% CI,-0.59–2.58, P = 0.22). However, TCM had a better effect in releasing the glomerular hyperfil

关键词： Angiotensin receptor antagonists angiotensin-converting enzyme inhibitors diabetic kidney disease meta-analysis traditional Chinese medicine

A quantum-search-based multi-classifier for image recognition

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 21-31页

作者： Lu liu Xingyu Wu Lufan Zhang chuan Wang School of Artificial Intelligence Beijing Normal University Applied Optics Beijing Area Major Laboratory Beijing Normal University

The multi-class classification of images is a pivotal challenge within the realm of image processing. As the volume of visual data continues to expand, there is a burgeoning interest in harnessing the unique capabilities of quantum computation to augment the efficiency of classification tasks. However, many existing methods for training quantum image multi-classifiers parallel classical machine learning techniques, where the requisite circuit measurements increase linearly with the volume of training data. This work introduces a novel approach for training a quantum image multi-classifier based on the quantum search algorithm. We have meticulously conducted rigorous experiments on a handwritten digit dataset, a classic benchmark in the field. The results have been meticulously compared with previous works, and the comparative analysis not only validates the efficiency of our proposed approach, requiring only O(N/b) measurements during training, but also highlights a significant quadratic speedup of the algorithm.

关键词： quantum computation image recognition quantum search algorithm

多功能果蔬保鲜装置的研制及大白菜真空预冷实验

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

制冷学报 2017年第1期38卷 107-112页

作者：申江张川刘升丁峰天津商业大学天津市制冷技术重点实验室天津300134 北京市农林科学院蔬菜研究中心国家蔬菜工程技术研究中心北京100097

本文介绍了一种兼具"真空预冷、减压贮藏、冰温真空干燥"三个功能于一体的果蔬保鲜装置及其工作原理,并对该装置的真空系统、制冷系统、加湿换气系统、控制系统的组成及工作过程进行了详细介绍与分析。利用该装置做了大白菜真空预冷及... 详细信息

本文介绍了一种兼具"真空预冷、减压贮藏、冰温真空干燥"三个功能于一体的果蔬保鲜装置及其工作原理,并对该装置的真空系统、制冷系统、加湿换气系统、控制系统的组成及工作过程进行了详细介绍与分析。利用该装置做了大白菜真空预冷及减压贮藏实验,结果表明,随着舱内压力的降低大白菜真空预冷过程可分为三个阶段:温度缓降、温度骤降及温度持平阶段;以大白菜失水率3.34%等实验数据分析了此装置的技术特点和独特优势。该装置可以从预冷、贮藏两个阶段缩短冷链物流的运转周期,减少果蔬搬运造成的机械损伤,从而将在商业化普及应用中创造更多的经济效益。

关键词：保鲜装置真空预冷与贮藏大白菜失水率

在线全文

学校读者我要写书评

暂无评论

基于脉冲涡流技术的柔性平面差分探头设计

仪表技术与传感器 2022年第10期 1-5页

作者：杨冉翟国富徐博蒋川流哈尔滨工业大学电器与电子可靠性研究所黑龙江哈尔滨150001

针对涡流探头对导电材料的表面和内部裂纹检测能力的不足,基于脉冲涡流检测技术设计了柔性平面差分探头,结合脉冲涡流检测的宽频谱和柔性平面差分线圈高信噪比的特点,可以在较大提离下检测表面缺陷以及检测更大埋深的内部缺陷。对铝试... 详细信息

针对涡流探头对导电材料的表面和内部裂纹检测能力的不足,基于脉冲涡流检测技术设计了柔性平面差分探头,结合脉冲涡流检测的宽频谱和柔性平面差分线圈高信噪比的特点,可以在较大提离下检测表面缺陷以及检测更大埋深的内部缺陷。对铝试件表面及内部缺陷检测进行了仿真与试验研究。仿真结果表明柔性平面探头产生的涡流能够有效渗透至试件底部,缺陷造成的涡流扰动产生时间随缺陷深度增加而增大。检测信号的电压峰值大小与峰值时间仍可用于识别缺陷深度,时间剖面曲线的正负相反峰波形信号特征可用于识别裂纹。实验结果表明柔性平面探头能够检测8.55 mm提离下的表面裂纹以及无提离下埋深4.8 mm的内部裂纹。同时,检测电压信号峰值对不同试件的裂纹深度进行定量,仿真与试验结果一致。

关键词：脉冲涡流柔性平面线圈缺陷检测深度定量

在线全文

学校读者我要写书评

暂无评论

HLS-Ⅱ恒温冷却水控制系统的设计与实现

原子能科学技术 2018年第6期52卷 1139-1143页

作者：孙晓康宋一凡李川蒋思远刘功发中国科学技术大学国家同步辐射实验室安徽合肥230029

HLS-Ⅱ恒温冷却水控制系统用于控制冷却水的温度变化,减少外部环境对设备的影响,以提高光源运行的稳定性。该系统是基于EPICS设计的分布式控制系统,采用串口以太网转换器MOXA6450将数字指示调节器UT55A-20接入到控制局域网中,温度控制在... 详细信息

HLS-Ⅱ恒温冷却水控制系统用于控制冷却水的温度变化,减少外部环境对设备的影响,以提高光源运行的稳定性。该系统是基于EPICS设计的分布式控制系统,采用串口以太网转换器MOXA6450将数字指示调节器UT55A-20接入到控制局域网中,温度控制在UT55A-20中实现,IOC运行在VMWare虚拟机上。系统自2015年以来运行稳定可靠,冷却水温度控制精度达到了±0.5℃的设计指标,为HLS-Ⅱ的稳定供光提供了必要的技术支持。

关键词：冷却水恒温控制 PID 分布式控制系统 EPICS

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao De-En Xu Ming-Lei Wu Ji-chuan liu Zi-Ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response