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Stability analysis of tunnel face reinforced with face bolts

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Journal of Mountain Science 2024年第7期21卷 2445-2461页

作者： TIAN Chongming jiang yin YE Fei OUYANG Aohui HAN Xingbo SONG Guifeng School of Highway Chang’an UniversityXi’an 710064China Civil Structural&Environmental EngineeringUniversity College CorkCork T12 YF78Ireland Yunnan Laman Expressway Co.Ltd. Xishuangbanna 666300China

Face bolting has been widely utilized to enhance the stability of tunnel face,particularly in soft soil ***,the influence of bolt reinforcement and its layout on tunnel face stability has not been systematically *** on the theory of linear elastic mechanics,this study delved into the specific mechanisms of bolt reinforcement on the tunnel face in both horizontal and vertical *** also identified the primary failure types of ***,a design approach for tunnel face bolts that incorporates spatial layout was established using the limit equilibrium method to enhance the conventional wedge-prism *** proposed model was subsequently validated through various means,and the specific influence of relevant bolt design parameters on tunnel face stability was ***,design principles for tunnel face bolts under different geological conditions were *** findings indicate that bolt failure can be categorized into three stages:tensile failure,pullout failure,and comprehensive *** cohesion,internal friction angle,bolt density,and overlap length can effectively enhance tunnel face *** to significant variations in stratum conditions,tailored design approaches based on specific failure stages are necessary for bolt design.

关键词： Highway tunnels Tunnel face Face bolts Limit equilibrium method Slice method

Experimental study on mix proportion optimization of anti-calcium dissolution shotcrete for tunnels based on response surface methodology

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Underground Space 2024年第2期15卷 203-220页

作者： Chongming Tian Yueping Tong Junyuan Zhang Fei Ye Guifeng Song yin jiang Meng Zhao School of Highway Chang’an UniversityXi’an 710064China Yunnan Laman Expressway Co. Ltd.Yunnan Xishuangbanna 666300China Hebei Traffic Planning Design Institute Shijiazhuang 050035China

Aiming at the issue of crystallization and blockage of drainage system due to the massive calcium loss from the tunnel shotcrete,a selfdesigned tunnel seepage crystallization modelling system was *** system was produced in conjunction with the initial tunnel support shotcrete construction and drainage pipe installation,and is capable of simulating both the seepage process of groundwater in the shotcrete and the process of crystallization in the drainage *** on three different mechanisms of anti-crystallization,which include absorbing free calcium,reducing the porosity and increasing hydrophobicity,antialkali agent,nano-calcium carbonate,and silane were selected to test,***,the suitable dosing ranges of these three external admixtures for resisting calcium loss in shotcrete were determined by single factor tests,which were 7%–11%,4%–8%,and 0.3%–0.5%,***,the response surface method was employed to evaluate the interaction of antialkali agent,nano-calcium carbonate and silane on calcium loss in shotcrete,and to establish the relationship between them,and thus to determine the admixture ratio that can effectively reduce calcium loss crystallization in shotcrete,with the optimal admixture amounts of antialkali agent being 9.242%,nano-calcium carbonate 4.889%and silane 0.366%.Lastly,the reliability of the model test results was verified by the microscopic analysis,and the results showed that the total amount of calcium dissolution in the optimized group could be reduced by 75%compared with the blank control group,and was basically consistent with that derived from the response surface regression model,validating the high accuracy of the buildup response surface regression *** present study can provide some ideas and references for reducing the seepage crystallization behavior of groundwater in the initial tunnel support shotcrete.

关键词： Tunnel engineering Calcium loss Crystallization blockage Model test Response surface methodology Interaction effect

Building imaginary-time thermal field theory with artificial neural networks

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Chinese Physics C 2024年第10期48卷 23-30页

作者： Tian Xu Lingxiao Wang Lianyi He Kai Zhou yin jiang Physics Department Beihang University37 Xueyuan RdBeijing 100191China Shanghai Research Center for Theoretical Nuclear Physics National Natural Science Foundation of ChinaFudan UniversityShanghai 200438China Department of Physics Tsinghua UniversityBeijing 100084China School of Science and Engineering The Chinese University of Hong KongShenzhenShenzhen 518172China Frankfurt Institute for Advanced Studies Ruth-Moufang-Str.160438 Frankfurt am MainGermany

In this paper,we introduce a novel approach in quantum field theories to estimate actions using artificial neural networks(ANNs).The actions are estimated by learning system configurations governed by the Boltzmann factor,e^(-s),at different temperatures within the imaginary time formalism of thermal field ***,we focus on the 0+1 dimensional quantum field with kink/anti-kink configurations to demonstrate the feasibility of the ***-mixture autoregressive networks(CANs)enable the construction of accurate effective actions with tractable probability density *** numerical results demonstrate that this methodology not only facilitates the construction of effective actions at specified temperatures but also adeptly estimates the action at intermediate temperatures using data from both lower and higher temperature *** capability is especially valuable for detailed exploration of phase diagrams.

关键词： artificial neural network imaginary-time thermal field theory effective model probability estimation

Chemoselective and Living/Controlled Polymerization of Alkenyl Methacrylates by the Phosphonium Ylide/Organoaluminum Lewis Pairs

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Chinese Journal of Polymer Science 2024年第2期42卷 159-167,I0005页

作者： Zhi-Kang Chen Wu-Chao Zhao Yi-Ling Zhao Cong-Lei Liu Liu-yin jiang Yue-Tao Zhang Hong-Ping Zhu State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen361005China State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun130012China

Chemoselective,living/controlled polymerizations of allyl methacrylate(AMA) and vinyl methacrylate(VMA) with/without methyl methacrylate(MMA) by using the phosphonium ylide/organoaluminum based Lewis pairs(LPs) have been *** P-ylide-2/AIMe(BHT)_(2)(Pylide-2=Ph_(3)P=CHMe and BHT=2,6-iBu_(2)-4-MeC_(6)H_(2)O) was demonstrated to be superior by which homopolymers PAMAs(M_(n)=27.6-111.5kg/mol and ■=1.14-1.25) and PVMAs(M_(n)=28.4-78.4 kg/mol and ■=1.12-1.18) and block copolymers PMMA-b-PAMA,PAMA-b-PVMA,PAMA-bPMMA,PMMA-b-PAMA-b-PMMA,PAMA-b-PMMA-b-PAMA,and PAMA-b-PVMA-b-PAMA were *** the polymerizations,all of the monomers were reacted by the conjugated ester vinyl groups leaving intactly the nonconjugated acryloxy *** pendant acryloxy groups attached to the main chain enable further to post-functionalization by the AIBN-induced radical "thiol-ene" reaction using PhCH_(2)*** thiolether side group-containing polymers PAMA-SCH_(2)Ph and PAMA-SCH_(2)Ph-b-PMMA-b-PAMA-SCH_(2)Ph were thus prepared.

关键词： Phosphonium ylide Alkenyl methacrylate Chemoselectivity Living/controlled polymerization Post-functionalization

融合多尺度Transformer的皮肤病变分割算法

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吉林大学学报（工学版） 2024年第4期54卷 1086-1098页

作者：梁礼明周珑颂尹江盛校棋江西理工大学电气工程与自动化学院江西赣州341000 华南理工大学计算机科学与工程学院广东广州510006

针对现有皮肤病变图像分割时缺乏多尺度特征提取,从而导致细节信息缺失和病变区域误分割的问题,本文提出一种融合多尺度Transformer的编解码网络皮肤病变分割算法。首先运用Transformer模块构建分层编码器,分层编码器从全局特征变化角... 详细信息

针对现有皮肤病变图像分割时缺乏多尺度特征提取,从而导致细节信息缺失和病变区域误分割的问题,本文提出一种融合多尺度Transformer的编解码网络皮肤病变分割算法。首先运用Transformer模块构建分层编码器,分层编码器从全局特征变化角度出发,多尺度分析皮肤病变区域;然后利用多尺度融合模块、通道注意力模块和联合层构建融合解码器,多尺度融合模块互补分层编码器中浅层网络信息与深层网络信息,增强空间信息和语义信息间的依赖关系,通道注意力模块能够有效识别特征丰富的通道,提高算法分割精度;最后引入扩展模块恢复图像大小以匹配实际需求。将该算法在ISBI2016、ISBI2017和ISIC2018三个公共数据集上进行实验测试,其像素精度分别为96.70%、94.50%和95.39%,平均交并比分别为91.69%、85.74%和89.29%,算法测试整体性能优于现有算法。仿真实验证明,多尺度Transformer编解码网络能够有效地分割皮肤病变图像。

关键词：计算机应用技术皮肤病变图像分割 Transformer 多尺度融合模块通道注意力模块

Network pharmacology and molecular docking analysis reveal insights into the molecular mechanism of Gualou Qumai Wan in clear cell renal cell carcinoma

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TMR Modern Herbal Medicine 2024年第2期7卷 11-18页

作者： Zhi-Qiang Wang Zhen-Yu Mu Bo Yang Tao Wang Zhi-Yong Su Shan-Chun Guo jiang-Xia yin Department of Urology Shouguang Hospital of Traditional Chinese MedicineShouguang 262700China Medical Insurance Office Shouguang Hospital of Traditional Chinese MedicineShouguang 262700China Intensive Care Unit Shouguang Hospital of Traditional Chinese MedicineShouguang 262700China Department of Anal Surgery Shouguang Hospital of Traditional Chinese MedicineShouguang 262700China Department of Neurosurgery Shouguang Hospital of Traditional Chinese MedicineShouguang 262700China RCMI Cancer Research Center Xavier University of LouisianaLA 1870125USA Department of Medical Oncology Shouguang Hospital of Traditional Chinese MedicineShouguang 262700China

Background:To initially clarify the potential therapeutic targets and pharmacological mechanism regarding Gualou Qumai Wan(GQW),a kind of traditional Chinese medicine(TCM),in clear cell renal cell carcinoma(ccRCC)by virtue of the network pharmacology analysis and molecular docking ***:The screening of bioactive components and targets of GQW was based on the Traditional Chinese Medicine System Pharmacology(TCMSP)and the UniProt platform served for standardizing their *** Mendelian Inheritance in Man(OMIM),PharmGkb,TTD,DrugBank and GeneCards databases were searched to collect the disease targets of *** assisted in constructing herb-compound-target(H-C-T)*** STRING database was searched for constructing the target protein-protein interaction(PPI)networks,while the R programming language served for analyzing GO functional terms and the KEGG pathways related to potential *** of core genes related to survival and tumor microenvironment(TME)were conducted respectively based on the GEPIA2 database and TIMER 2.0 *** Protein Atlas(HPA)and The Cancer Genome Atlas(TCGA)helped to obtain core genes’protein expression as well as transcriptome expression *** Vina software validated the molecular docking regarding GQW components and pivotal ***:The constructed H-C-T networks mainly had 33 compounds and 65 targets.A topological analysis of the PPI network identified that ESR1,AKT1,HIF1A,PTGS2,TP53 and VEGFA serve as core targets in the way GQW affects *** to the GO and KEGG pathway enrichment analyses,the effects of GQW are mediated by genes related to hypoxia and oxidative stress as well as the Chemical carcinogenesis-receptor activation and PI3K-Akt signaling ***1 shows a close relation to the recruitment of various immune cells and can remarkably affect disease prognosis according to *** docking and molecular dynamics simulations showed that diosgenin has

关键词： Gualou Qumai Wan AKT1 PI3K-Akt signaling pathway network pharmacology diosgenin clear cell renal cell carcinoma

鸭疫里默氏杆菌九型分泌系统(T9SS)分泌蛋白B739_0093的功能鉴定

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微生物学报 2024年第7期64卷 2407-2418页

作者：江茵罗睿心程安春刘马峰西南动物疫病防控技术教育部工程研究中心四川成都611130 四川省动物疫病防控国际联合研究中心四川成都611130 动物疫病与人类健康四川省重点实验室四川成都611130 四川农业大学动物医学院禽病防治研究中心四川成都611130

【目的】鸭疫里默氏杆菌是引起鸭浆膜炎的一种革兰氏阴性病原菌,该菌编码的九型分泌系统(type IX secretion system,T9SS)参与滑动、致病等过程。前期研究结果表明,鸭疫里默氏杆菌CH-1株B739_0093基因在限铁培养条件明显上调。序列分析... 详细信息

【目的】鸭疫里默氏杆菌是引起鸭浆膜炎的一种革兰氏阴性病原菌,该菌编码的九型分泌系统(type IX secretion system,T9SS)参与滑动、致病等过程。前期研究结果表明,鸭疫里默氏杆菌CH-1株B739_0093基因在限铁培养条件明显上调。序列分析表明,B739_0093编码蛋白含有一个T9SS分泌蛋白保守的C端结构域,然而其具体功能未知。本研究旨在鉴定该基因编码蛋白是否被T9SS分泌,以及在该菌致病中的作用。【方法】用荧光定量PCR检测B739_0093是否被铁离子和铁转运调节子(ferric uptake regulator,Fur)调控;用大肠杆菌表达重组B739_0093截短蛋白制备多克隆抗体,通过Western blotting检测是否由T9SS分泌;构建B739_0093基因缺失株,通过毒力和定殖试验鉴定B739_0093在鸭疫里默氏杆菌致病中的功能。【结果】荧光定量PCR结果表明,B739_0093基因在铁离子限制性培养基明显上调,此调控是由调控蛋白Fur介导的;Western blotting结果显示,B739_0093基因编码蛋白在亲本株RA CH-1主要定位在分泌物中,而在T9SS缺失株定位在菌体且不能在分泌物被检测到;与亲本株RA CH-1相比,RA CH-1ΔB739_0093对雏鸭的致病力减弱,在雏鸭各组织器官的定殖能力明显降低。【结论】B739_0093基因编码蛋白是由鸭疫里默氏杆菌T9SS分泌的,其表达受铁离子及Fur调控,并且参与了该菌的致病。

关键词：鸭疫里默氏杆菌九型分泌系统毒力

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地幔榴辉岩包体的同位素定年方法研究进展

地球科学与环境学报 2024年第1期46卷 114-126页

作者：蒋蕾茵孙晶黄铖铮吴琪中国石油大学(北京)地球科学学院北京102249 中国石油大学(北京)油气资源与探测国家重点实验室北京102249 自然资源部信息中心北京100812

地幔榴辉岩包体是寄主岩浆从地球深部地幔携带到地表的俯冲洋壳碎片,作为一种高压变质岩,它可能记录着有关大洋地壳原岩、板块俯冲以及后期交代变质过程等重要信息,因此其年龄也显得格外重要。通过统计全球超过500个已发表的地幔榴辉岩... 详细信息

地幔榴辉岩包体是寄主岩浆从地球深部地幔携带到地表的俯冲洋壳碎片,作为一种高压变质岩,它可能记录着有关大洋地壳原岩、板块俯冲以及后期交代变质过程等重要信息,因此其年龄也显得格外重要。通过统计全球超过500个已发表的地幔榴辉岩包体的年龄结果,对比几种常用的地幔榴辉岩包体同位素定年方法,讨论了不同方法的优缺点及适用情况。结果表明:金红石U-Pb和全岩Rb-Sr、Sm-Nd、Lu-Hf全岩等时线法一般给出的是寄主岩浆的年龄或地幔交代的时间,而榴辉岩中的硫化物Re-Os等时线年龄,锆石U-Pb上交点年龄,Sm-Nd、Lu-Hf石榴子石-单斜辉石双矿物等时线年龄以及锆石Hf亏损地幔模式年龄对于其原岩年龄及板块俯冲时代有较为可观的应用前景;地幔榴辉岩包体最古老年龄的峰值分布在3.1~2.8 Ga,与Kaapvaal和西伯利亚克拉通构造拼合的时间吻合,可能代表着全球地幔榴辉岩包体的最早形成时代,也预示着板块构造可能于中太古代开启。

关键词：板块构造地幔榴辉岩包体放射性同位素定年方法锆石U-Pb年龄 Sm-Nd等时线年龄 Lu-Hf等时线年龄硫化物Re-Os等时线年龄

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水-苦草-沉积物系统对聚乙烯微塑料的响应

环境科学 2024年第8期45卷 4610-4618页

作者：李佳依鲁仙赵志淼韩浩宇张饮江上海海洋大学海洋生态与环境学院上海201306 同济大学环境科学与工程学院污染控制与资源化研究国家重点实验室上海200092

水生态系统中的微塑料对生态安全和环境健康造成严重威胁,受到广泛关注.为了揭示水-苦草-沉积物系统对于微塑料暴露的响应,将苦草暴露于不同质量分数(1%~5%,沉积物湿重质量分数)的聚乙烯微塑料(PE-MPs)中,分别研究了PE-MPs对系统中水质... 详细信息

水生态系统中的微塑料对生态安全和环境健康造成严重威胁,受到广泛关注.为了揭示水-苦草-沉积物系统对于微塑料暴露的响应,将苦草暴露于不同质量分数(1%~5%,沉积物湿重质量分数)的聚乙烯微塑料(PE-MPs)中,分别研究了PE-MPs对系统中水质理化指标、沉水植物形态特征、生理性状、抗氧化系统和沉积物中微生物群落结构的影响.结果表明,PE-MPs处理组对于水体理化性质的改变不显著,PE-MPs处理组显著抑制了植株株高、氧化应激指标和抗氧化系统.1%PE-MPs处理组株高的增长仅为对照组的47.44%,叶绿素a含量为对照组的81.04%,过氧化氢酶(CAT)活性、丙二醛(MDA)含量和过氧化物酶(POD)活性较对照组分别提高了233.70%、117.82%和61.62%.不同质量分数的PE-MPs对沉积物中的微生物群落结构存在一定的影响.上述结果有助于完善水-沉水植物-沉积物系统中PE-MPs生态风险的评价体系.

关键词：聚乙烯微塑料生态系统水质指标苦草微生物群落响应