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Nano Research 2024年第4期17卷 3130-3138页

作者： Zedong Hu Juanjuan Lu Hongyi Dou jianan shen James PBarnard Juncheng Liu Xinghang Zhang Haiyan Wang School of Electrical and Computer Engineering Purdue UniversityWest LafayetteIN 47906USA School of Materials Engineering Purdue UniversityWest LafayetteIN 47906USA

Oxide-metal based nanocomposite thin films have attracted great interests owing to their unique anisotropic structure and physical properties.A wide range of Au-based oxide-metal nanocomposites have been demonstrated,while other metal systems are scarce due to the challenges in the initial nucleation and growth as well as possible interdiffusions of the metallic nanopillars.In this work,a unique anodic aluminum oxide(AAO)template was used to grow a thin Co seed layer and the following self-assembled metal-oxide(Co-BaTiO_(3))vertically aligned nanocomposite thin film layer.The AAO template allows the uniform growth of Co-seeds and successfully deposition of highly ordered Co pillars(with diameter<5 nm and interval between pillars<10 nm)inside the oxide matrix.Significant magnetic anisotropy and strong magneto-optical coupling properties have been observed.A thin Au-BaTiO_(3) template was also later introduced for further enhanced nucleation and ordered growth of the Co-nanopillars.Taking the advantage of such a unique nanostructure,a large out-of-plane(OP)coercive field(Hc)of~5000 Oe has been achieved,making the nanocomposite an ideal candidate for high density perpendicular magnetic tunneling junction(p-MTJ).A strong polar magneto-optical Kerr effect(MOKE)has also been observed which inspires a novel optical-based reading method of the MTJ states.

关键词： vertically aligned nanocomposite(VAN) Co BaTiO_(3) thin film magneto-optical coupling magnetic anisotropy

A generalized synthesis method for freestanding multiferroic twodimensional layered supercell oxide films via a sacrificial buffer layer

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Nano Research 2023年第7期16卷 10559-10566页

作者： jianan shen Benson Kunhung Tsai Ke Xu Anyu Shang James PBarnard Yizhi Zhang Rahul Tripathi Zhihong Chen Xinghang Zhang Haiyan Wang School of Materials Engineering Purdue UniversityWest LafayetteIndiana 47907USA Elmore Family School of Electrical and Computer Engineering Purdue UniversityWest LafayetteIndiana 47907USA Birck Nanotechnology Center Purdue UniversityWest LafayetteIndiana 47907USA

Multiferroics are an intriguing family of materials due to the simultaneous presence of two ferroic orderings,namely,ferroelectricity and ferromagnetism.They are scientifically and technologically important and have numerous potential applications,such as four-state logic memories and multiferroic tunneling junctions.However,the growth of epitaxial singlephase multiferroic thin films typically requires single crystalline oxide substrates,which hinders their future integration with Sibased devices.In this study,we report a generalized synthesis method that uses the polydimethylsiloxane(PDMS)-assisted wetetching method with an Sr_(3)Al_(2)O_(6)(SAO)sacrificial layer to transfer freestanding single-phase multiferroic Bi_(2)NiMnO_(6)(BNMO)films from conventional SrTiO_(3)(STO)substrates onto a Si wafer.The structures and properties of the films have been characterized before and after the transfer.These transferred films possess good multiferroic properties on Si wafers,indicating full compatibility with modern Si technology.This method can be generally applicable to other Bi-based multiferroic materials as well.Lastly,the original STO substrates after the transfer process have been recycled for preparing new batches of freestanding BNMO films,indicating a low-cost and sustainable method for manufacturing large-volume freestanding complex oxide thin films.

关键词： multiferroics freestanding films wet-transfer SAO sacrificial layer recyclable substrates sustainable

Novel self-assembled two-dimensional layered oxide structure incorporated with Au nanoinclusions towards multifunctionalities

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Nano Research 2023年第1期16卷 1465-1472页

作者： Di Zhang Xingyao Gao Juanjuan Lu Ping Lu Julia Deitz jianan shen Hongyi Dou Zihao He Zhongxia Shang C.Austin Wade Xinghang Zhang Aiping Chen Haiyan Wang School of Materials Engineering Purdue UniversityWest LafayetteIN 47907USA Center for Integrated Nanotechnologies(CINT) Los Alamos National LaboratoryLos AlamosNM 87545USA Sandia National Laboratories AlbuquerqueNM 87185USA School of Electrical and Computer Engineering Purdue UniversityWest LafayetteIN 47907USA Thermo Fisher Scientific HillsboroOR 97124USA

Two-dimensional(2D)layered oxides have recently attracted wide attention owing to the strong coupling among charges,spins,lattice,and strain,which allows great flexibility and opportunities in structure designs as well as multifunctionality exploration.In parallel,plasmonic hybrid nanostructures exhibit exotic localized surface plasmon resonance(LSPR)providing a broad range of applications in nanophotonic devices and sensors.A hybrid material platform combining the unique multifunctional 2D layered oxides and plasmonic nanostructures brings optical tuning into the new level.In this work,a novel self-assembled Bi2MoO6(BMO)2D layered oxide incorporated with plasmonic Au nanoinclusions has been demonstrated via one-step pulsed laser deposition(PLD)technique.Comprehensive microstructural characterizations,including scanning transmission electron microscopy(STEM),differential phase contrast imaging(DPC),and STEM tomography,have demonstrated the high epitaxial quality and particle-in-matrix morphology of the BMO-Au nanocomposite film.DPC-STEM imaging clarifies the magnetic domain structures of BMO matrix.Three different BMO structures including layered supercell(LSC)and superlattices have been revealed which is attributed to the variable strain states throughout the BMO-Au film.Owing to the combination of plasmonic Au and layered structure of BMO,the nanocomposite film exhibits a typical LSPR in visible wavelength region and strong anisotropy in terms of its optical and ferromagnetic properties.This study opens a new avenue for developing novel 2D layered complex oxides incorporated with plasmonic metal or semiconductor phases showing great potential for applications in multifunctional nanoelectronics devices.

关键词： layered oxides plasmonic strain anisotropy multifunctionality

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测耙数量对进气道稳态畸变特性测量的影响

空气动力学学报 2024年第1期42卷 26-32,I0001页

作者：王霄沈天荣潘英郭佳男任智博沈阳飞机设计研究所沈阳110035 中国飞行试验研究院西安710089 沈阳发动机研究所沈阳110015

在现代战斗机进气道相关试验中,受低速辅助进气门打开和隐身大S弯管道、大迎角侧滑角飞行姿态等复杂因素影响,进气道流场畸变较大,不同测耙数量的测试结果相差较大。国内外对进气道出口流场稳态畸变的测量及计算有较多研究,但鲜有测耙... 详细信息

在现代战斗机进气道相关试验中,受低速辅助进气门打开和隐身大S弯管道、大迎角侧滑角飞行姿态等复杂因素影响,进气道流场畸变较大,不同测耙数量的测试结果相差较大。国内外对进气道出口流场稳态畸变的测量及计算有较多研究,但鲜有测耙数量对进气道稳态畸变测量影响的全面对比研究。本文采用测耙测量进气道大压力梯度区和低压区并计算其稳态畸变,针对进气道风洞试验、全尺寸进发联合台架试验和进发匹配试飞,对常用的6支耙和8支耙形式测量结果进行对比研究。结果表明,对于形状复杂的战斗机进气道而言,进气道出口流场的测试需要尽可能采用8支测耙的测量方式,才能取得满意的结果。特别是舰载战斗机在舰面环境下,受舰首来流及偏流板反射等因素影响,进气道流场更加复杂,且发动机工作在特殊加力状态,对进发匹配稳定性要求也更加苛刻,更有必要采用8支测耙的测量方式。

关键词：进气道进发匹配试飞测试风洞试验畸变测耙进发相容性

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基于思维链的大语言模型知识蒸馏

数据采集与处理 2024年第3期39卷 547-558页

作者：李荣涵浦荣成沈佳楠李栋栋苗启广西安电子科技大学计算机科学与技术学院西安710000 武警工程大学反恐指挥信息工程教育部重点实验室(立项) 西安710086

思维链(Chain of thought,CoT)提示使大语言模型能够按照具体推理步骤处理复杂的任务,让大语言模型在常识推理、数学逻辑推理和可解释性等方面表现出更强的能力。然而,CoT方法的主要缺点在于其对庞大语言模型的依赖,这些模型通常拥有数... 详细信息

思维链(Chain of thought,CoT)提示使大语言模型能够按照具体推理步骤处理复杂的任务,让大语言模型在常识推理、数学逻辑推理和可解释性等方面表现出更强的能力。然而,CoT方法的主要缺点在于其对庞大语言模型的依赖,这些模型通常拥有数百亿的参数,在大规模部署方面面临挑战。为此,本文提出一种基于思维链的大模型知识蒸馏方法,主要目标在于充分利用大型语言模型的思维推理能力,通过知识蒸馏技术,引导小模型解决复杂任务。以大型模型为教师模型,小型模型为学生模型,通过获取教师模型的推理数据来微调学生模型。通过更改数据生成方式、基于聚类的问答示例采样、示例启发式纠错以及答案的自适应生成等一系列精心设计的方法,使教师模型的生成过程更高效,生成的推理数据质量更高、数量更多,从而更好地微调学生模型,使其获得强大的推理能力,实现高效的知识蒸馏。这一研究框架旨在建立一个有效的知识传递机制,使得大模型的深度思考能够有效指导小模型,为解决复杂任务提供更为智能且高效的解决方案。通过这种方式,希望能够克服大模型部署的挑战,并促进语言模型在现实世界中的应用和进步。

关键词：思维链逻辑推理知识蒸馏微调

“艾武大模型+”:一种军事大模型系统的开发与实证

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数据采集与处理 2024年第3期39卷 588-597页

作者：崔翛龙高志强姬纬通沈佳楠张敏邱鑫源武警工程大学反恐指挥信息工程教育部重点实验室(立项) 西安710086

智能化指挥是新型指挥控制理论研究的重要方向,大模型是智能交互、任务规划和辅助决策等智能化指挥能力实现的重要支撑。本文兼顾理论与实践,梳理大模型军事能力需求,设计面向智能化指挥的大模型应用框架,提出“艾武大模型+”的系统架... 详细信息

智能化指挥是新型指挥控制理论研究的重要方向,大模型是智能交互、任务规划和辅助决策等智能化指挥能力实现的重要支撑。本文兼顾理论与实践,梳理大模型军事能力需求,设计面向智能化指挥的大模型应用框架,提出“艾武大模型+”的系统架构、信息流程和协同架构,梳理工程实现的关键技术,以智能化指挥实证案例及选型分析验证“艾武大模型+”系统在多模态交互和特定任务军语理解的能力优势,拓展有/无人平台的末端协同和指令控制,为重大国防军事专项、智能化指挥研究与落地应用提供参考。

关键词：军事大模型提示工程智能化指挥专用语料多模态交互

Interaction between reactive oxygen species and hormones during the breaking of embryo dormancy in Sorbus pohuashanensis by exogenous nitric oxide

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Journal of Forestry Research 2022年第2期33卷 435-444页

作者： Hao Wang Shuoran Tang jianan Wang Hailong shen Ling Yang State Key Laboratory of Tree Genetics and Breeding School of ForestryNortheast Forestry UniversityHarbin 150040People’s Republic of China

The breaking of dormancy mediated by reac-tive nitrogen species(RNS)is related to the accumulation of reactive oxygen species(ROS)in germinating embryos but the underlying mechanism is unclear.The objectives of this study were:(1)to explore the relationship between RNS-mediated dormancy release and ROS accumulation in germinating embryos of Sorbus pohuashanensis;and,(2)to investigate the relationships among germination time,ROS metabolism,and endogenous hormone synthesis.We studied the effects of exogenous nitric oxide(NO)donor sodium nitroprusside(SNP),the NO scavenger(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide(PTIO),abscisic acid(ABA),the exogenous ethylene donor ethrel,and the ethylene receptor inhibitor 2,5-norbornadien(NBD)on embryo germination and seedling growth.Embryos were released from dormancy by pretreatment with NO or ethylene, which was related to increased ethylene biosyn-thesis and decreased ABA levels. Breaking of dormancy by SNP was related to increased levels of ethylene, hydrogen peroxide, and glutathione, increased activities of superoxide dismutase and glutathione peroxidase, and decreased levels of ABA, superoxide anions, and malondialdehyde. These effects of nitric oxide were especially significant in seedling hypocotyls and radicles. These results demonstrate that NO can break S. pohuashanensis embryo dormancy by induc-ing ethylene biosynthesis, and that this signalling pathway is closely related to ROS accumulation and the antioxidant defence response.

关键词： NO-dependent dormancy Hydrogen peroxide Ethylene Embryo germination Mountain ash(Sorbus pohuashanensis)

软式康复机器人手套对脑卒中患者上肢及手功能影响Meta分析

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康复学报 2024年第2期34卷 167-175页

作者：余婷婷沈宇薇万国盟励建安南京医科大学康复医学院江苏南京210029 南京医科大学第一附属医院江苏南京210029

目的通过Meta分析探讨软式康复机器人手套(SRG)对脑卒中后患者上肢-手运动功能的影响。方法计算机检索PubMed、Web of Science、The Cochrane Library、Embase、中国知网(CNKI)、万方数据库(Wanfang Data)、中国生物医学文献服务系统(... 详细信息

目的通过Meta分析探讨软式康复机器人手套(SRG)对脑卒中后患者上肢-手运动功能的影响。方法计算机检索PubMed、Web of Science、The Cochrane Library、Embase、中国知网(CNKI)、万方数据库(Wanfang Data)、中国生物医学文献服务系统(CBMdisc)、维普中文科技期刊数据库(VIP)等数据库有关SRG干预脑卒中后上肢-手运动功能障碍患者的临床随机对照试验(RCTs),检索时限为建库至2023年8月。主要结局指标包括Fugl-Meyer评定量表上肢部分(FMA-UE)评分、改良Barthel指数(MBI)评分、Wolf运动功能(WMFT)评分、握力、箱盒测试(BBT)评分、上肢动作研究量表(ARAT)评分。数据提取和文献质量评价由2名研究员独立进行,采用RevMan 5.4软件进行Meta分析。连续性变量采用均数差(MD)或标准化均数差(SMD)表示,计算其95%置信区间(CI)。根据I 2值判断异质性大小,若P≥0.10,I 2≤50%,各研究间不存在异质性或异质性较小,采用固定效应模型;若P50%,各研究间异质性较大,采用随机效应模型。结果本研究共纳入13篇文献,共计653例患者。Meta分析结果显示,与对照组比较,试验组FMAUE评分明显更高[MD=8.05,95%CI(7.01,9.09),Z=15.20,P<0.000 01],MBI评分明显更高[MD=9.91,95%CI(2.65,17.17),Z=2.68,P=0.007],WMFT评分明显更高[MD=8.39,95%CI(6.99,9.78),Z=11.81,P<0.000 01],握力明显更高[SMD=0.39,95%CI(0.11,0.67),Z=2.75,P=0.006],ARAT评分明显更高[MD=11.18,95%CI(9.10,13.26),Z=10.53,P<0.000 01],BBT评分差异无统计学意义[(MD=0.53,95%CI(-1.47,2.53),Z=0.52,P=0.60)]。结论 SRG可以提高脑卒中患者上肢-手运动功能和日常生活活动能力,但今后仍需纳入更多大样本、高质量的RCTs以进一步验证其疗效。

关键词：脑卒中上肢运动功能手功能软式康复机器人手套日常生活活动能力 Meta分析

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失效模式与效应分析结合“三圈层”管控模式在二级医院发热门诊感染管控中的应用

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中西医结合护理（中英文） 2024年第1期10卷 154-156页

作者：沈佳楠季沈慧徐灵玲启东市第三人民医院江苏南通226200 启东市第五人民医院江苏南通226231 启东市妇幼保健院江苏南通226200

目的探讨失效模式与效应分析(FMEA)理论结合“三圈层”管控模式在二级医院发热门诊感染管控中的应用价值。方法选取2020年1月至2021年12月于启东市第三人民医院发热门诊就诊的100例患者作为本次研究的研究对象,依据随机抽样法将患者等... 详细信息

目的探讨失效模式与效应分析(FMEA)理论结合“三圈层”管控模式在二级医院发热门诊感染管控中的应用价值。方法选取2020年1月至2021年12月于启东市第三人民医院发热门诊就诊的100例患者作为本次研究的研究对象,依据随机抽样法将患者等分为观察组和对照组,各50例。对照组接受常规管控,观察组接受FMEA理论结合“三圈层”管控。比较2组的物体表面洁净度、院内感染发生情况及感染防控质量评分。结果观察组的物体表面合格率为75.51%,明显高于对照组的56.12%(P<0.05)。观察组的院内感染发生率为4.00%,略低于对照组的16.00%(P<0.05)。观察组的各项感染防控质量评分及加权总分均明显高于对照组(P均<0.05)。结论FMEA理论结合“三圈层”管控模式可有效改善发热门诊的就诊环境,提高物体表面的洁净度,降低院内感染发生率,提高感染防控质量。

关键词：发热门诊失效模式与效应分析 “三圈层”管控院内感染

柴胡纳米乳的制备工艺、质量评价及退热药效学研究

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中国现代应用药学 2024年第1期41卷 42-47页

作者：石佳楠宋信莉刘兴德陈欢欢杨小双杨胜磊沈丽万开龙贵州中医药大学贵阳550000

目的筛选柴胡纳米乳的处方和制备方法,并对其进行质量评价和退热药效作用的研究。方法对乳化剂和助乳化剂进行初步筛选,再通过伪三元相图筛选处方,并对制备的柴胡纳米乳的外观性状、粒径分布、结构类型、稳定性及含量进行质量评价。... 详细信息

目的筛选柴胡纳米乳的处方和制备方法,并对其进行质量评价和退热药效作用的研究。方法对乳化剂和助乳化剂进行初步筛选,再通过伪三元相图筛选处方,并对制备的柴胡纳米乳的外观性状、粒径分布、结构类型、稳定性及含量进行质量评价。进一步将Wistar大鼠随机分成空白对照组,模型对照组,阳性对照组(阿司匹林组),柴胡纳米乳高、中、低剂量组(18.00,9.00,3.00 g·kg^(-1));除空白对照组外,其余各组大鼠制备发热大鼠病理模型。按照预定的实验要求分别给予相应的药物,于0.5,1,1.5,2,3 h记录各组大鼠的体温变化情况,观察柴胡纳米乳的退热作用。结果柴胡纳米乳的最佳处方为吐温-80 6 g与正丁醇3 g,柴胡提取物溶于纯水为水相20 mL,柴胡油为油相2 g。室温下制剂为黄褐色澄清透明液体,水包油型纳米乳,平均粒径为(77.21±3.66)nm,多分散系数为0.28±0.04,Zeta电位为(–18.81±1.42)mV,所含柴胡皂苷为3.071 mg·mL^(-1),具备良好的稳定性。动物实验中,与模型对照组比较,阿司匹林组、柴胡纳米乳高剂量组首次给药后的各时间段肛温明显降低(P<0.01),柴胡纳米乳中剂量组首次给药2,3 h后肛温明显降低(P<0.01)。结论所制备的柴胡纳米乳外观透明,稳定性好,并且对发热大鼠模型具有较好的解热作用。

关键词：柴胡纳米乳制备工艺伪三元相图质量评价药效学研究