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Experimental Study on Engineering Behavior of Solidified Soil for Scour Repair and Protection

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China Ocean Engineering 2024年第4期38卷 625-635页

作者： WU Xiao-ni li Ru-yu SHU jian TANG Chao CHEN Jin-jian WANG Hui-li jianG Hai-li WANG Xiao State Key Laboratory of Ocean Engineering Department of Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China Shanghai Road and Bridge Group Co. Ltd.Shanghai 200433China Shanghai Engineering Research Center of Urban Infrastructure Renewal Shanghai 200032China jiangsu Kunze Technology Co. Ltd.Nanjing 210000China

A new scour countermeasure using solidified slurry for offshore foundation has been proposed *** solidified slurry is pumped to seabed area around foundation for scour protection or pumped into the developed scour holes for scour repair as the fluidized material solidifies *** the pumping operation and solidification,the engineering behaviors of solidified slurry require to be considered synthetically for the reliable application in scour repair and protection of ocean engineering such as the pumpability related flow value,flow diffusion behavior related rheological property,anti-scour performance related retention rate in solidification and bearing capacity related strength property after *** this study,a series of laboratory tests are conducted to investigate the effects of mix proportion(initial water content and binder content)on the flow value,rheological properties,density,retention rate of solidified slurry and unconfined compressive strength(UCS).The results reveal that the flow value increases with the water content and decreases with the binder *** the solidified slurry exhibits Bingham plastic behavior when the shear rate is larger than 5 s^(-1).The Bingham model has been employed to fit the rheology test results,and empirical formulas for obtaining the density,yield stress and viscosity are established,providing scientific support for the numerical assessment of flow and diffusion of solidified *** rate of solidified slurry decreases with the water flow velocity and flow value,which means the pumpability of solidified slurry is contrary to anti-scour *** unconfined compressive strength after solidification reduces as the water content increases and binder content decreases.A design and application procedure of solidified soil for scour repair and protection is also proposed for engineering reference.

关键词： scour repair and protection solidified soil pumpability strength flow properties anti-scour performance

Interpretation of Chinese Expert Consensus on the Diagnosis and Management Strategy of Patients with Statin Intolerance: A guiding file for helping to lipid management for Chinese population

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Journal of Geriatric Cardiology 2024年第7期21卷 713-715页

作者： jian-Jun li Cardiometabolic Center National Center for Cardiovascular DiseaseChinese Academy of Medical ScienceFuwai HospitalBeijingChina

It is well-known that elevated low-density lipoprotein cholesterol(LDL-C)is a causal risk factor for atheroscler-otic cardiovascular disease(ASCVD),statins are cornerstone drugs for the cause-based treatment of ASCVD,which has created a new era for ASCVD ***,statin intolerance is not clinically uncommon,which there are several issues with confu-sion and ***,a file named Chinese Expert Consensus on the Diagnosis and Management Strategy of Pa-tients With Statin Intolerance,like a navigator,has recently been published written by a team of experts from the Cardiovascular Metabolic Medicine Professional Committee,Expert Committee of the National Center for Cardiovascular Diseases aiming to en-hance the standardized clinical application of statins and improve the prevention and clinical *** this article,author briefly summarized the key points of above consensus in order to helping to comprehending the content of the consensus sugges-tions.

关键词： Expert Strategy corners

On Affine Hypersurfaces with Parallel Cubic Form Relative to Affineα-connection

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Acta Mathematica Sinica,English Series 2024年第4期40卷 1099-1114页

作者： Ce Ce li Cheng xing Hui Yang XU School of Mathematics and Statistics He’nan University of Science and TechnologyLuoyang 471023P.R.China School of Mathematical Sciences and LPMC Nankai UniversityTianjin 300071P.R.China

Similar to Nomizu-Pinkall's geometric characterization of the Cayley surface and Hu-li-Zhang's characterization of the Cayley hypersurface,how can one characterize the generalized Cayley hypersurfaces?In this paper,by the affineα-connection of statistical manifolds,we study affine hypersurfaces with parallel cubic form relative to the affineα-*** the main results,we complete the classification of such hypersurfaces if its affine metric is either definite,or Lorentzian withα≠-***,we give a new characterization of the generalized Cayley hypersurfaces to answer the question.

关键词： Affine hypersurface parallel cubic form affineα-connection Einstein metric

Time-delay effect and design of closed-loop control system of circulation control airfoil

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Chinese Journal of Aeronautics 2024年第10期37卷 50-67页

作者： lingxiao li Heyong XU Zheng xing Abdul Samad KHAN School of Aeronautics Northwestern Polytechnical UniversityXi’an 710072China National Key Laboratory of Aircraft Configuration Design Xi’an 710072China

In this paper,unsteady numerical simulation of jet Circulation Control(CC)is carried out with the NACA0012-CC airfoil as the research *** dynamic process from the opening of jet slot and adjustment of jet intensity to the stable state of jet control effect is *** time-delay effect and flow mechanism of jet are *** mechanism of jet momentum coefficient and moment coefficient fluctuating with time is *** fluctuation of jet momentum coefficient is caused by the change of the pressure coefficient distribution on the Coanda surface or the structure of the wave system inside the jet,and the oscillation frequency of the wave system structure of the under-expansion supersonic jet reaches 1481 Hz at the opening *** on the aerodynamic model and Proportional-Integral-Derivative(PID)control theory,the closed-loop control system of CC airfoil is *** parameters of PID control system are adjusted by the Genetic Algorithm(GA),which significantly improves the response ability of the control system to step,ramp and sine signals,and improves the dynamic performance of the *** at the special time-delay effect of jet control,Long Short-Term Memory(LSTM)neural network module is added to the control system to predict the target input signal,which strengthens the prediction ability of GA-PID control system to the target signal at the next time *** using LSTM neural network correction,the control hysteresis caused by jet time-delay effect is alleviated,and the response ability of the control system is effectively ***,the designed LSTM-GA-PID control system is applied to the NACA0012-CC airfoil for the pitch control simulation *** test results show that the control system designed in this paper has good dynamic performance and can respond quickly and accurately to complex input signals,which confirms the effectiveness of the control system.

关键词： Circulation control Unsteady numerical simulation Time-delay effect Control system Long short-term memory

An aptamer-driven DNA nanodevice for improved delivery of synthetic immunostimulants

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Nano Research 2024年第10期17卷 9078-9083页

作者： Dejie Lu Zhenghan Di Lele li jian Zhao li Zheng Guangxi Engineering Center in Biomedical Materials for Tissue and Organ Regeneration Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and ApplicationGuangxi Key Laboratory of Regenerative MedicineThe First Affiliated Hospital of Guangxi Medical UniversityGuangxi Medical UniversityNanning 530021China CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety National Center for Nanoscience and TechnologyBeijing 100190China

Efficient delivery of therapeutics to immune cells remains a formidable challenge for cancer *** this work,we demonstrate that an aptamer-driven DNA nanodevice,constructed through linkage of a synthetic immunostimulant(Toll-like receptor 9 agonist:CpG motif)to an aptamer,could significantly enhance the immunostimulatory activity by facilitating the uptake and retention of therapeutics in *** administration of the DNA nanodevice results in efficient tumor growth inhibition in both breast cancer and melanoma mouse *** studies suggest that the DNA nanodevice leads to reeducation of tumor-associated macrophages and ultimately to reversing the tumor immune *** strategy for aptamer-mediated and vehicle-free delivery of immunostimulatory oligonucleotides provides a potential platform for cancer immunotherapy.

关键词： aptamer immunostimulatory oligonucleotides DNA nanodevice tumor-associated macrophages cancer therapy

link Prediction Method Fusion with Local Structural Entropy for Directed Network

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Chinese Journal of Electronics 2024年第1期33卷 204-216页

作者： Shuxin liU Hongchang CHEN Lan WU Kai WANG xing li People’s liberation Army Strategic Support Force Information Engineering University

link prediction utilizes accessible network information to complement or predict the network *** is an important prerequisite for link prediction which means links more likely occurs between two similar nodes. Existing methods utilize the similarity of nodes but neglect of network structure. However the link direction leads to a far more complex structure and contains more information useful than the undirected networks. Most classic methods are difficult to depict the distribution of the network structure with incidental direction so the similarity characteristics of the network structure itself are lost. In this respect, a new method of local structure entropy is proposed to depict the directed structural distribution characteristics, which can be used to evaluate the degree of local structural similarity of nodes and then applied to link prediction methods. Experimental results on 8 real directed networks show that this method is effective for both area under the receiver operating characteristic curve(AUC)and ranking-score measures, and improved predictive capacity of the baseline methodology.

关键词： Correlation Current measurement Area measurement Prediction methods Receivers Benchmark testing Entropy

Impact of Mo/Ni alloying on microstructural modulation and low-temperature toughness of high-strength low-alloy steel

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Journal of Iron and Steel Research International 2024年第7期31卷 1746-1762页

作者： Wei liu Hong-li Zhao Bing-xing Wang Yong Tian State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819LiaoningChina

The high-strength low-alloy steel plates with varying Ni/Mo contents were manufactured using the thermos-mechanical control *** investigation was conducted to explore the effect of Ni/Mo microalloying on microstructure evolution and mechanical properties of the *** results revealed that the increase in Ni content from 1 to 2 wt.%reduced the transition temperature of ferrite and the growth range of ferritic grain was narrowed,which promoted grain *** optimized combination of grain size,high-angle grain boundaries(HAGBs),and martensite-austenite(M-A)islands parameter contributed to the excellent impact toughness of S1 steel at-100℃(impact absorbed energy of 218.2 J at-100℃).As the Mo increases from 0 to 2 wt.%,the matrix structure changes from multiphase structure to granular bainite,which increases the average effective grain size to~4.62 pm and reduces HAGBs proportion to~36.22%.With these changes,the low-temperature impact toughness of S3 steel is *** addition,based on the analysis of the characteristics of crack propagation path,it was found that M-A islands with low content(~2.21%)and small size(~1.76 pm)significantly retarded crack propagation,and the fracture model of M-A islands with different morphologies was further ***,correlation between behaviour of delamination and toughness was further analysed by observing delamination size and impact energy parameters.

关键词： High-strength low-alloy steel Microstructural regulation Ni addition Mo addition Crack propagation Low-temperature toughness

Rockburst prediction and prevention in underground space excavation

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Underground Space 2024年第1期14卷 70-98页

作者： jian Zhou Yulin Zhang Chuanqi li Haini He Xibing li School of Resources and Safety Engineering Central South UniversityChangsha 410083China Laboratory 3SR CNRS UMR 5521Grenoble Alpes UniversityGrenoble 38000France

The technical challenges associated with deep underground space activities have become increasingly *** these challenges,one major concern is the assessment of rockburst risks and the instability of rock *** research has been conducted by numerous scholars to mitigate the risks and prevent occurrences of rockburst through various assessment *** incidents commonly occur during the excavation of hard rock in underground environments,posing severe threats to personnel safety,equipment integrity,and operational ***,it is crucial to systematically document real cases of rockburst,allowing for a comprehensive understanding of the underlying mechanisms and triggering *** understanding will contribute to the advancement of rockburst prediction and prevention *** selection of an appropriate rockburst assessment method is a fundamental aspect in underground ***,there is a limited number of studies that summarize and compare different prediction and prevention methods of *** paper aims to address this gap by analyzing global trends using CiteSpace software since *** discusses rockburst classification and characteristics,comprehensively reviews research findings related to rockburst prediction,including empirical,simulation,mathematical modeling,and microseismic monitoring ***,the paper presents a compilation of current rockburst prevention ***,the paper emphasizes the significance of control strategies,which provide key insights into the effective utilization of stored energy within ***,the paper concludes by suggesting six directions for implementing intelligent management techniques to mitigate hazards during underground operations and reduce the probability of rockburst incidents.

关键词： Rockburst Underground space Scientometric analysis Characteristic analysis Rockburst prediction Rockburst prevention

Application of Optical Hydrogels in Environmental Sensing

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Energy & Environmental Materials 2024年第3期7卷 311-336页

作者： Shuo Yang Shruti Sarkar xing Xie Dan li jianmin Chen Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention(LAP3) Department of Environmental Science and EngineeringFudan UniversityShanghai 200438China School of Civil and Environmental Engineering Georgia Institute of TechnologyAtlanta Georgia 30332USA

The ever-increasing complexity of environmental pollutants urgently warrants the development of new detection *** based on the optical properties of hydrogels enabling fast and easy in situ detection are attracting increasing *** this paper,the data from 138 papers about different optical hydrogels(OHs)are extracted for statistical *** detection performance and potential of various types of OHs in different environmental pollutant detection scenarios were evaluated and compared to those obtained using the standard detection *** on this analysis,the target recognition and sensing mechanisms of two main types of OHs are reviewed and discussed:photonic crystal hydrogels(PCHs)and fluorescent hydrogels(FHs).For PCHs,the environmental stimulus response,target receptors,inverse opal structures,and molecular imprinting techniques related to PCHs are reviewed and ***,the different types of fluorophores(i.e.,compound probes,biomacromolecules,quantum dots,and luminescent microbes)of FHs are ***,the potential academic research directions to address the challenges of applying and developing OHs in environmental sensing are proposed,including the fusion of various OHs,introduction of the latest technologies in various fields to the construction of OHs,and development of multifunctional sensor arrays.

关键词： environmental sensors fluorescent hydrogel optical hydrogel photonic crystal hydrogel pollution detection