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Study on the Stabilizing Conditions of W/O Microemulsion

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Journal of Shanghai University(English Edition) 2001年第4期5卷 338-340页

作者： PAN Qing yi, LU Qing, CHENG Zhi xuan, ZHANG jian ping, dong Xiao wen Department of Chemistry, College of Sciences, Shanghai University, Shanghai 200436, China Department of Chemistry College of Sciences Shanghai University Shanghai China

The stabilizing conditions of W/O microemulsion of Tx 6～C 4H 9OH/c C 6H 12 /H 2O system were studied by visual observation. The result shows that when the weight ratio of Tx 6 to C 4H 9OH is 4∶1,the W/O microemulsion system has stabilizing and extensive regions, and the system is insensitive to the values of pH and in the range of room *** accordance with the theoretical value of HLB,the suitable value of HLB for Tx 6 and C 4H 9OH to compose microemulsion is greater than 9,less than or equal to 10.

关键词： Tx 6 C 4H 9OH W/O microemulsion

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不同紫花苜蓿品种瘤胃降解特性比较

草地学报 2016年第6期24卷 1323-1330页

作者：孙建平董宽虎山西农业大学动物科技学院山西太谷030801

为研究不同紫花苜蓿(Medicago sativa L.)品种在牛瘤胃中的降解规律,本试验以10个紫花苜蓿品种为材料,以3头装有永久性瘘管的晋南牛作为试验动物,采用尼龙袋法测定不同紫花苜蓿品种干物质(DM)、粗蛋白质(CP)、中性洗涤纤维(NDF)和酸性... 详细信息

为研究不同紫花苜蓿(Medicago sativa L.)品种在牛瘤胃中的降解规律,本试验以10个紫花苜蓿品种为材料,以3头装有永久性瘘管的晋南牛作为试验动物,采用尼龙袋法测定不同紫花苜蓿品种干物质(DM)、粗蛋白质(CP)、中性洗涤纤维(NDF)和酸性洗涤纤维(ADF)的瘤胃降解率和降解参数。结果表明:不同紫花苜蓿品种DM,CP,NDF和ADF的降解率随着其在瘤胃内培养时间的延长,均呈升高趋势,但不同品种在同一培养时间段内的降解率存在显著差异;不同紫花苜蓿品种的有效降解率(ED)的差异较大,‘WL-319HQ DM’的ED最高,显著高于‘中苜一号’和‘首领’(P<0.01);‘金皇后’CP的ED显著高于除‘赛迪’之外的其他品种;‘WL-168HQ’、‘中苜一号’NDF的ED显著高于除‘首领’之外的其他品种;‘三得利’、‘皇后’ADF的ED显著高于其他品种(P<0.05)。由此可见,不同紫花苜蓿品种在瘤胃内的降解特性不同。

关键词：紫花苜蓿尼龙袋法瘤胃降解

Long-term effects of biodegradable versus durable polymer-coated sirolimus-eluting stents on coronary arterial wall morphology assessed by virtual histology intravascular ultrasound

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Chinese Medical Journal 2011年第6期124卷 836-844页

作者： LIU Hui-liang JIN Zhi-geng LUO jian-ping MA dong-xing YANG Sheng-li LIU Ying HAN Wei JING Li-min MENG Rong-ying ZHANG Jiao Department of Cardiology General Hospital of Chinese People's Armed Police Forces Beijing 100039 China

Background The durable presence of polymer coating on drug-eluting stent （DES） surface may be one of the principal reasons for stent thrombosis. The long-term coronary arterial response to biodegradable polymer-coated sirolimus-eluting stent （BSES） in vivo remained *** Forty-one patients were enrolled in this study and virtual histology intravascular ultrasound （VH-IVUS） was performed to assess the native artery vascular responses to BSES compared with durable polymer-coated SES （DSES） during long-term follow-up （median： 8 months）. The incidence of necrotic core abutting to the lumen was evaluated at *** With similar in-stent late luminal loss （0.15 mm （0.06-0.30 mm） vs. 0.19 mm （0.03-0.30 mm）, P=0.772）, the overall incidence of necrotic core abutting to the lumen was significantly less in BSES group than in DSES group （44% vs.63%, P 〈0.05）（proximal 18%, stented site 14% and distal 12% in BSES group, proximal 19%, stented site 28% and distal 16% in DSES group）. The DSES-treated segments had a significant higher incidence of necrotic core abutting to the lumen through the stent struts （73% vs. 36%, P 〈0.01）. In addition, more multiple necrotic core abutting to the lumen was observed in DSES group （overall： 63% vs. 36%, P 〈0.05）. Furthermore, when the stented segments with necrotic core abutting to the lumen had been taken into account only, DSES-treated lesions tended to contain more multiple necrotic core abutting to the lumen through the stent struts than BSES-treated lesions （74% vs. 33%）, although there was no statistically significant difference between them （P=0.06）.Conclusions By VH-IVUS analysis at follow-up, a greater frequency of stable lesion morphometry was shown in lesions treated with BSESs compared with lesions treated with DSESs. The major reason was BSES produced less toxicity to the arterial wall and facilitated neointimal healing as a result of polymer coating on DES surface biodegraded as time went by.

关键词： biodegradable polymers drug-eluting stents virtual histology intravascular ultrasound

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直肠癌前切除术后吻合口漏危险因素分析

中国实用外科杂志 2018年第10期38卷 1174-1176页

作者：潘博周建平董明中国医科大学附属第一医院胃肠外科辽宁沈阳110001

目的探讨直肠癌前切除术后发生吻合口漏的危险因素。方法回顾性分析2014年1月至2018年6月中国医科大学附属第一医院胃肠外科行直肠癌前切除术的262例病人的临床资料,对资料中的31个变量与吻合口漏的关系进行单因素和多因素分析,以探讨... 详细信息

目的探讨直肠癌前切除术后发生吻合口漏的危险因素。方法回顾性分析2014年1月至2018年6月中国医科大学附属第一医院胃肠外科行直肠癌前切除术的262例病人的临床资料,对资料中的31个变量与吻合口漏的关系进行单因素和多因素分析,以探讨发生吻合口漏的危险因素。结果行直肠癌前切除术的262例病人中有41例(15.6%)发生吻合口漏,单因素分析结果显示,远端直肠切割闭合器触发数(P=0.040)、吻合方式(P=0.030)、围手术期输血(P<0.001)、术后腹泻(P<0.001)与术后吻合口漏明显相关;多因素分析发现,吻合方式(P=0.008)、围手术期输血(P<0.001)、术后腹泻(P<0.001)是术后发生吻合口漏的独立危险因素。结论直肠癌前切除术中建议尽量减少吻合器击发次数,避免不必要的围手术期输血,并重视术后早期腹泻,有利于降低吻合口漏的发生率。

关键词：直肠癌前切除术吻合口漏危险因素

Study on functional connections between supraoptic nucleus and stomach in rats

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Study on functional connections between supraoptic nucleus a...

Dielectric-ion-conductive ZnNb2O6 layer enabling rapid desolvation and diffusion for dendrite-free Zn metal batteries

中国生理学会第23届全国会员代表大会暨生理学学术大会

作者： Chang-Liang LU,Zhao-ping LI,jian-ping ZHU,dong-Qin ZHAO,Hong-Bin AI~* College of Life Sciences,Shandong Normal University,Jinan,250014

＜正＞Objective:Many evidences support the standpoint that there are functional connections between the hypothalamic paraventricular nucleus（PVN） and the stomach,then what about the supraoptic nucleus（SON） which is similar with the PVN in the localization and the neurons organization is *** question was probed in the present ***:The rats were anesthetized and then divided into four groups randomly. GroupⅠ,the neuronal discharge was recorded extracellularly in the NTS,DMV or SON before and after the cold normal saline（4℃） was perfused into the stomach from esophagus and effused from the duodenum for 5 min. GroupⅡ,the rats were stimulated by cold saline as GroupⅠ,and 60 min later,the Fos expression of the NTS,DMV and SON was examined via immunohistochemistry technique,***Ⅲwas the control to GroupⅡand was not perfused with cold saline（4℃）.GroupⅣ,gastric motility was recorded continuously by inserting a latex balloon into pylorus through the forestomach which connected with pressure *** the amplitude, duration,frequency and motility index of gastric contraction waves within 10 min before and after microinjection of L-Glu into the SON were *** data represent the mean±***:In GroupⅠ,the discharge frequency caused by the gastric lower temperature increased in all the three nuclei,but differed in *** and SON had significant difference（P＜0.05） than before the perfusion of cold saline[e.g.,SON,（6.85±1.71） spikes/s vs （4.5±0.68） spikes/s,n=7],but NTS had no significant *** GroupⅡ,Fos expression in NTS,DMV and SON was respectively greater than that of GroupⅢ（P＜0.05 or＜0.01）（*** SON,the number of Fos-positive neurons is 188.23±16.45 vs 102.82±7.39,n=5）.In GroupⅣ,microinjection of L-Glu（5 nmol/L,n=7） into SON significantly inhibited gastric motility,motility index before injection was 1482.1±708.2 and 1185.5±639.2 after injection （P＜0.05）.Conclusion:These data strongly suggest that there are functional c

关键词： supraoptic nucleus neuronal discharge c-Fos expression gastric motility

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Journal of Energy Chemistry 2025年第1期100卷 693-701页

作者： Haifeng Yang jian Wang Panpan Zhang Xiaomin Cheng Qinghua Guan Jing dong Bixian Chen Lujie Jia Jing Zhang Yongzheng Zhang Yunjian Liu Hongzhen Lin School of Materials Science and Engineering Jiangsu University i-Lab & CAS Key Laboratory of Nanophotonic Materials and Devices Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of Sciences Helmholtz Institute Ulm (HIU) Karlsruhe Institute of Technology (KIT) School of Materials Science and Engineering Xi'an University of Technology State Key Laboratory of Chemical Engineering East China University of Science and Technology

Rechargeable aqueous zinc-metal batteries （AZMBs） are promising candidates for large-scale energy storage systems due to their low cost and high ***,their performance and sustainability are significantly hindered by the sluggish desolvation kinetics at the electrode/electrolyte interface and the corresponding hydrogen evolution reaction where active water molecules tightly participate in the Zn（H2O）62+solvation ***,learnt from self-generated solid electrolyte interphase （SEI） in anodes,the dielectric but ion-conductive zinc niobate nanoparticles artificial layer is constructed on metallic Zn surface （ZNB@Zn）,acting as a rapid desolvation *** zincophilic and dielectric-conductive properties of ZNB layer accelerate interfacial desolvation/diffusion and suppress surface corrosion or dendrite formation,achieving uniform Zn plating/stripping behavior,as confirmed by electronic/optical microscopies and interface spectroscopical measurements together with theoretical ***,the as-prepared ZNB@Zn electrode exhibits excellent cycling stability of over 2000 h and robust reversibility （99.54%） even under high current density and depth of discharge ***,the assembled ZNB@Zn-based full cell displays high capacity-retention rate of 80.21%after 3000 cycles at 5 A g-1and outstanding rate performance up to 10 A *** large-areal pouch cell is stabilized for hundreds of cycles,highlighting the bright prospects of the dielectric but ion-conductive layer in further application of AZMBs.

关键词： Zn metal battery Dielectric artificial layer Rapid ion diffusion Zincophilic diffusion Active water inhibition

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引入药物经济学评价指数的医药营销组合策略

上海交通大学学报 2007年第S1期41卷 117-120页

作者：李建平董正英上海交通大学安泰经济与管理学院上海200052

面对环境的变化,医药营销模式必将随着医疗模式的改变而进行彻底的变革.通过综合分析,尝试在市场营销组合策略中引入药物经济学评价指数,构造新的医药营销组合策略(从4P→5P),以期为医药市场营销活动提供新的思路和途径.

关键词：药物经济学信息不对称博弈医疗模式

Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats

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World Journal of Gastroenterology 2025年第1期31卷 93-109页

作者： ping Zhang Ying Zhu Pu Chen Tong Zhou Zhe-Yi Han Jun Xiao jian-Feng Ma Wen Ma Peng Zang Ying Chen Graduate School Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina Key Laboratory of Aerospace Nutrition and Food Engineering China Astronaut Research and Training CenterBeijing 100094China Department of Gastroenterology The Air Force Medical CenterBeijing 100142China Department of Blood Transfusion Air Force Medical CenterBeijing 100142China

BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility *** pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal ***,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal *** cells are the pacemakers of gastrointestinal *** To investigate the effects of Bifidobacterium lactis(***)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit *** The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 *** tail group was given *** BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/***&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and *** fecal flora and mucosal flora of rats in each group were detected by 16S *** Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic *** microgravity reduced the expressions of SCF and c-kit,and increased the express

关键词： Simulated microgravity Rat Intestinal flora Gastrointestinal motility Stem cell factor/c-kit signaling pathway

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下肢外伤后皮肤放线菌病1例

中国皮肤性病学杂志 2017年第1期31卷 65-66页

作者：蒋小云何剑萍王永东程浩浙江大学医学院附属邵逸夫医院浙江杭州310016

患者男,49岁。右膝关节外伤后7年,局部肿胀结节伴疼痛5年。患者曾至多家医院就诊,被考虑为皮肤软组织感染,予以不同抗生素治疗,效果不佳。我院行皮肤组织活检,发现放射状排列的菌丝,周围有嗜酸性透明物质,予有效抗生素治疗的反应良好。

关键词：皮肤放线菌病诊断组织病理治疗