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一种主变压器热点温度实时计算解析模型

电力自动化设备 2016年第11期36卷 147-151页

作者：杨志超吴奕王坚崔莉蒋春容朱海兵葛乐南京工程学院江苏省配电网智能技术与装备协同创新中心江苏南京211167 国网江苏省电力公司江苏南京210024

基于油浸式变压器的顶层油温-绕组等效热路,提出了一种主变压器绕组热点温度的解析模型,该模型能够根据当前采集的主变负载系数和顶层油温数据,实时计算热点温度。相应提出了绕组时间常数的确定方案。通过对某334 MV·A/500 k V主变压... 详细信息

基于油浸式变压器的顶层油温-绕组等效热路,提出了一种主变压器绕组热点温度的解析模型,该模型能够根据当前采集的主变负载系数和顶层油温数据,实时计算热点温度。相应提出了绕组时间常数的确定方案。通过对某334 MV·A/500 k V主变压器进行实例计算与分析,并将结果与通过GB/T 15164—1994标准中的热点温度计算公式计算的结果进行比较,验证了所提出热点温度模型及计算方法的有效性和正确性,同时指出了GB/T 15164—1994标准中热点温度计算公式存在的缺陷。

关键词：变压器主变压器等效热路热点温度顶层油温绕组时间常数解析模型

基于改进细胞链表算法的分子动力学模拟性能优化模型

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计算机科学 2013年第2期40卷 12-15页

作者：金明灿胡长军李建江苗庆松北京科技大学计算机与通信工程学院北京100083 中国科学院计算技术研究所计算机体系结构国家重点实验室北京100083 平壤机械大学信息工程学院平壤70050

在改进的细胞链表算法中,细胞大小的减少会降低该算法的通信量和粒子之间距离计算的次数,同时会增加邻居细胞的数量。多细胞分子动力学算法是分子动力学模拟中普遍使用的并行算法。将改进细胞链表算法的基本思想应用到多细胞分子动力学... 详细信息

在改进的细胞链表算法中,细胞大小的减少会降低该算法的通信量和粒子之间距离计算的次数,同时会增加邻居细胞的数量。多细胞分子动力学算法是分子动力学模拟中普遍使用的并行算法。将改进细胞链表算法的基本思想应用到多细胞分子动力学算法中,推导出了一个分子动力学模拟性能评价模型,并据此提出一个优化模型来加速分子动力学模拟。实验结果表明,根据该优化模型确定的细胞大小可以提高分子动力学模拟程序的性能。

关键词：并行计算细胞链表算法多细胞分子动力学算法性能评价细胞大小的优化

Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

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World Journal of Clinical Oncology 2025年第1期16卷 43-52页

作者： Zhi-jian Tang Yuan-Ming Pan Wei li Rui-Qiong Ma jian-liu Wang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Cancer Research Center Beijing Chest HospitalBeijing 101149China Department of Thoracic Surgery Sichuan Provincial People's HospitalChengdu 610072Sichuan ProvinceChina

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment *** To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural *** Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression *** genes were sourced from the MitoCarta3.0 *** discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation *** the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were *** In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy *** average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation *** average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation *** The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

关键词： Ovarian cancer Mitochondria Prognosis Immunotherapy Neural network

Feasible synthesis of porous h-BN by Mg^(2+)induced lattice dislocations for hydrogen and ammonia storage

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Nano Research 2025年第1期18卷 94-99页

作者： Xiaojia Huang Zihao Wang Yihan Kong li jiang Baolin Wang jiangtao Jia Heping Ma Guangshan Zhu Key Laboratory of Polyoxometalate and Reticular Material Chemistry of Ministry of Education Northeast Normal UniversityChangchun 130024China School of Chemical Engineering and Technology Xi’an Jiaotong University Xi’an 710049China

Hexagonal boron nitride(h-BN)is a two-dimensional(2D)layered material with a structure similar to graphite and it has potential as a hydrogen and ammonia storage ***,dense packing in the standard h-BN structure limits its surface area and prevents the B and N from being adsorption *** this study,the addition of Mg^(2+)during h-BN synthesis facilitated the growth of lattice dislocations and led to a crosslinked three-dimensional(3D)porous structure.A proposed formation mechanism for porous h-BN was confirmed by several characterization routes,most clearly by high-resolution transmission electron microscopy(HRTEM).Porous Mg/BNs exhibited high H_(2)and NH_(3)uptakes and showed potential for H_(2)and NH_(3)storage.

关键词： hexagonal boron nitride porous material dislocation gas storage

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急倾斜极软厚煤层走向长壁综放开采技术研究

煤炭学报 2017年第2期42卷 286-292页

作者：王家臣赵兵文赵鹏飞杨胜利安建华江志义中国矿业大学(北京)资源与安全工程学院北京100083 放顶煤开采煤炭行业工程研究中心北京100083 冀中能源峰峰集团有限公司河北邯郸056000

以峰峰集团山西大远煤业1201急倾斜工作面为背景,系统研究了急倾斜厚煤层走向长壁综放开采的基本问题,指出支架的合理设计是该类煤层成功开采的首要条件,支架设计要充分考虑急倾斜厚煤层综放开采的顶板活动规律,以工作面上部顶板的冲击... 详细信息

以峰峰集团山西大远煤业1201急倾斜工作面为背景,系统研究了急倾斜厚煤层走向长壁综放开采的基本问题,指出支架的合理设计是该类煤层成功开采的首要条件,支架设计要充分考虑急倾斜厚煤层综放开采的顶板活动规律,以工作面上部顶板的冲击载荷确定支架的工作阻力。同时急倾斜支架要有足够的抗侧向挤压能力,结合工作面采放工艺确定侧护板的抗挤压能力。急倾斜厚煤层综放开采的顶煤放出体与煤岩分界面具有明显的不对称性。结合顶煤放出规律、支架稳定性等综合确定采放工艺,提出"下行动态分段、段内上行放煤"的采放工艺,适用于急倾斜厚煤层走向长壁综放开采,可最大限度地减少采放过程中对支架的不利影响,并可获得较高的顶煤采出率。工作面安装前需对软弱底板进行加固。

关键词：急倾斜厚煤层走向长壁综放开采顶煤放出规律采放工艺支架设计

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模板浸润法制备聚苯乙烯纳米管阵列

功能材料与器件学报 2005年第2期11卷 139-142,148页

作者：宋国君佘希林李建江袁芳北京化工大学材料学院北京100029 青岛大学化工学院青岛266071 青岛大学高职学院青岛266071

采用一种简单的物理技术—聚合物溶液或熔体浸润多孔阳极氧化铝(AAO)模板的方法,在孔径仅为200nm的AAO模板中制备聚苯乙烯(PS)纳米管阵列。SEM和TEM测试结果表明:熔体法制备的纳米管壁厚约为110nm;5.0wt%和10.0wt%的PS溶液制备的纳米管... 详细信息

采用一种简单的物理技术—聚合物溶液或熔体浸润多孔阳极氧化铝(AAO)模板的方法,在孔径仅为200nm的AAO模板中制备聚苯乙烯(PS)纳米管阵列。SEM和TEM测试结果表明:熔体法制备的纳米管壁厚约为110nm;5.0wt%和10.0wt%的PS溶液制备的纳米管壁厚分别为70nm和80nm。并初步探索了模板法制备聚合物纳米管的多次浸润机理。

关键词：聚合物纳米管模板浸润法常规分子量PS 多孔阳极氧化铝

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新疆冰上运动项目教练员队伍现状分析

吉林体育学院学报 2014年第3期30卷 61-64页

作者：李建疆张兆新疆大学体育教学研究部新疆乌鲁木齐830046

运用文献资料法、问卷调查法、专家访谈法对新疆冰上运动项目教练员队伍现状进行调查和分析研究,找出差距和问题所在,提出发展对策和建议,从而为提高新疆冰上运动项目教练员队伍水平提供科学详实依据,为新疆冰上运动项目健康持续发展提... 详细信息

运用文献资料法、问卷调查法、专家访谈法对新疆冰上运动项目教练员队伍现状进行调查和分析研究,找出差距和问题所在,提出发展对策和建议,从而为提高新疆冰上运动项目教练员队伍水平提供科学详实依据,为新疆冰上运动项目健康持续发展提供客观参考。

关键词：新疆冰上运动项目教练员

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浸润AAO模板组装一维聚合物纳米阵列

现代化工 2007年第11期27卷 34-36页

作者：佘希林宋国君彭智王树龙李建江马永为周迪青岛大学高分子材料研究所山东青岛266071

以孔径为200 nm的多孔氧化铝膜(AAO)为模板,采用聚合物溶液或熔体浸润模板纳米孔的物理技术,进行了多种一维聚合物纳米阵列的制备研究。结果表明PA66、PP、ABS、TPU、PVDF、PA11等多种聚合物纳米管都能形成规整的阵列。探讨了聚合物性... 详细信息

以孔径为200 nm的多孔氧化铝膜(AAO)为模板,采用聚合物溶液或熔体浸润模板纳米孔的物理技术,进行了多种一维聚合物纳米阵列的制备研究。结果表明PA66、PP、ABS、TPU、PVDF、PA11等多种聚合物纳米管都能形成规整的阵列。探讨了聚合物性质、制备工艺与一维纳米管结构的关系和机理。

关键词：聚合物纳米管 AAO 机理

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang Xin liu jian Zhang Ya Gao Shuyue li Cui Chang Xiang liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein