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A deep kernel method for lithofacies identification using conventional well logs

Petroleum Science 2023年第3期20卷 1411-1428页

作者： Shao-Qun Dong Zhao-Hui Zhong Xue-Hui Cui Lian-Bo Zeng Xu Yang jian-jun liu Yan-Ming Sun jing-Ru Hao State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China Collge of Science China University of PetroleumBeijing102249China College of Geoscience China University of PetroleumBeijing102249China

How to fit a properly nonlinear classification model from conventional well logs to lithofacies is a key problem for machine learning *** methods(e.g.,KFD,SVM,MSVM)are effective attempts to solve this issue due to abilities of handling nonlinear features by kernel *** mining of log features indicating lithofacies still needs to be improved for kernel ***,this work employs deep neural networks to enhance the kernel principal component analysis(KPCA)method and proposes a deep kernel method(DKM)for lithofacies identification using well *** includes a feature extractor and a *** feature extractor consists of a series of KPCA models arranged according to residual network structure.A gradient-free optimization method is introduced to automatically optimize parameters and structure in DKM,which can avoid complex tuning of parameters in *** test the validation of the proposed DKM for lithofacies identification,an open-sourced dataset with seven con-ventional logs(GR,CAL,AC,DEN,CNL,LLD,and LLS)and lithofacies labels from the Daniudi Gas Field in China is *** are eight lithofacies,namely clastic rocks(pebbly,coarse,medium,and fine sand-stone,siltstone,mudstone),coal,and carbonate *** comparisons between DKM and three commonly used kernel methods(KFD,SVM,MSVM)show that(1)DKM(85.7%)outperforms SVM(77%),KFD(79.5%),and MSVM(82.8%)in accuracy of lithofacies identification;(2)DKM is about twice faster than the multi-kernel method(MSVM)with good *** blind well test in Well D13 indicates that compared with the other three methods DKM improves about 24%in accuracy,35%in precision,41%in recall,and 40%in F1 score,*** general,DKM is an effective method for complex lithofacies *** work also discussed the optimal structure and classifier for *** re-sults show that(m_(1),m_(2),O)is the optimal model structure and linear svM is the optimal classifier.(m_(1),m_(2),O)means there

关键词： Lithofacies identification Deepkernel method Well logs Residual unit Kernel principal component analysis Gradient-free optimization

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Observation of topological charge transformations in acoustic vortex using passive periodic systems

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 140-147页

作者： Di-Chao Chen Xie liu Changqing Xu Da-jian Wu Ying Cheng Xiao-jun liu School of Physics and Technology Nanjing Normal University Key Laboratory of Modern Acoustics School of Physics Nanjing University

Vortex transmutation utilizes a periodic system, which not only enables the alteration of the topological charge(TC) of unstable input vortices but also facilitates their transformation into stable structures. This approach is crucial for investigating the characteristics of vortices in various wave systems. Here, we achieve acoustic vortex TC transmutation by employing a welldesigned dual-structured plate external system(DPES). The interactions between the acoustic vortex and the finite-order discrete rotational symmetry lead to the transformation of its topological charge when complete rotational symmetry is broken to Nthorder discrete symmetry. Our results experimentally demonstrate the acoustic vortex TC transmutation based on passive artificial structures, enabling numerous applications in particle manipulation and information multiplexing as well as advancing our understanding and control over free-space acoustic vortices.

关键词： acoustic vortex topological charge transformation artificial structure

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基于PIV分析的含石量对土石混合体边坡破坏过程及模式的影响

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岩土力学 2017年第3期38卷 696-704页

作者：龚健刘君大连理工大学建设工程学部辽宁大连116024

为了探明含石量对土石混合体边坡渐进破坏的影响,进行了5种不同含石量边坡的静力超载试验。在加载过程中测得作用于边坡顶部的力和位移,同时采集边坡侧面的高清图像。通过对比PIV(particle image velocimetry)分析结果与FLAC^(3D)数值... 详细信息

为了探明含石量对土石混合体边坡渐进破坏的影响,进行了5种不同含石量边坡的静力超载试验。在加载过程中测得作用于边坡顶部的力和位移,同时采集边坡侧面的高清图像。通过对比PIV(particle image velocimetry)分析结果与FLAC^(3D)数值模拟结果揭示了边坡在静力超载作用下的破坏过程并表明PIV分析结果能够体现土石混合体中砾石对剪切带的影响。对比不同含石量边坡的PIV分析结果,发现剪切带都呈"y"型,但含石量对剪切带的发展有重要影响。随着含石量增加,一方面剪切带受砾石影响而逐渐呈现偏转和曲折的特点,并发现剪切带发展过程中的两种"绕石"模式;另一方面,边坡破坏模式从整体破坏到局部分级破坏逐渐过渡,破坏模式的转折点位于含石量30%~53%的区间内。

关键词：土石混合体边坡含石量破坏过程破坏模式 PIV

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Comparison of the autofluorescence bronchoscope and the white light bronchoscope in airway examination

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Chinese Journal of Cancer 2010年第12期29卷 1018-1022页

作者： Yun Li Xiao Li Xi-Zhao Sui Liang Bu Zu-Li Zhou Fan Yang Yan-Guo liu Hui Zhao jian-Feng Li jun liu Guan-Chao jiang jun Wang Department of Thoracic Surgery People's Hospital Peking University Beijing 100044 P. R. China

Background and Objective: The sensitivity and accuracy of white light bronchoscopy (WLB) in airway examination are low. Autofluorescence bronchoscope (AFB) can determine early lesions in bronchial mucosa more sensitively, but it has seldom performed in China. To assess the clinical value of the AFB in airway examination, we compared the sensitivity and specificity of the AFB and WLB in detecting cancer of the airway mucosa. Methods: Between September 2009 and May 2010, bronchoscope examinations using both the AFB and WLB were performed on 136 patients, 95 men and 41 women with a median age of 61.5 years (ranged from 25 to 84 years). There were 46 lesions located in the central airway, 84 in the peripheral lung parenchyma, and 6 in the mediastinal region. All patients received local and general anesthesia and were subsequently examined with the WLB and AFB in tandem. All procedures were completed safely. Abnormal visual findings were recorded, and biopsies of the affected regions were collected for pathologic examination. Results: Of 241 regions sampled for biopsy, 76 sites contained malignant lesions, whereas 165 sites contained benign lesions. The AFB detected 72 of the 76 malignant lesions, but the WLB detected only 50. The sensitivities of the AFB and WLB were 94.7% and 65.8%, respectively, and the specificities were 57.0% and 83.6%, respectively. The negative predictive values of the AFB and WLB were 95.9% and 84.1%, respectively. Conclusions: The AFB is more sensitive than the WLB in detecting cancerous lesions in the mucosa, and is an effective airway examination.

关键词：病理检查支气管气道萤光自体检测灵敏度空军基地色光

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Pathophysiological consequences and treatment strategy of obstructive jaundice

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World Journal of Gastrointestinal Surgery 2023年第7期15卷 1262-1276页

作者： jun-jian liu Yi-Meng Sun Yan Xu Han-Wei Mei Wu Guo Zhong-Lian Li Department of Hepatobiliary and Pancreatic Surgery Tianjin Medical University Nankai HospitalTianjin 300102China Graduate School Tianjin Medical UniversityTianjin 300070China Graduate School Tianjin University of Traditional Chinese MedicineTianjin 301617China

Obstructive jaundice(OJ)is a common problem in daily clinical ***,completely understanding the pathophysiological changes in OJ remains a challenge for planning current and future *** effects of OJ are widespread,affecting the biliary tree,hepatic cells,liver function,and causing systemic *** lack of bile in the intestine,destruction of the intestinal mucosal barrier,and increased absorption of endotoxins can lead to endotoxemia,production of proinflammatory cytokines,and induce systemic inflammatory response syndrome,ultimately leading to multiple organ dysfunction *** management of OJ includes adequate water supply and electrolyte replacement,nutritional support,preventive antibiotics,pain relief,and itching *** surgical treatment of OJ depends on the cause,location,and severity of the *** drainage,surgery,and endoscopic intervention are potential treatment options depending on the patient's *** addition to modern medical treatments,Traditional Chinese medicine may offer therapeutic benefits for OJ.A comprehensive search was conducted on PubMed for relevant articles published up to August *** review discusses in detail the pathophysiological changes associated with OJ and presents effective strategies for managing the condition.

关键词： Jaundice Obstructive Pathophysiology Treatment strategy Traditional Chinese medicine

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Breast Cancer Resistance Protein Expression and 5-Fluorouracil Resistance

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Biomedical and Environmental Sciences 2008年第4期21卷 290-295页

作者： jian-HUI YUAN JIN-QUAN CHENG LONG-YUAN jianG WEI-DONG JI LIANG-FENG GUO jian-jun liu XING-YUN XU JING-SONG HE XIAN-MING WANG ZHI-XIONG ZHUANG Faculty of Preventive Medicine School of Public Health Sun Yat-Sen University Guangzhou 510080Guangdong China Toxicology Laboratory Municipal Center for Disease Control and PreventionShenzhen 518020 Guangdong China Department of Emergency The Second Affiliated Hospital of Sun Yat-Sen University Guangzhou 510120 Guangdong China Department of General Surgery Shenzhen Second People＇s Hospital Shenzhen 518035 Guangdong China

Objective To filtrate breast cancer resistance protein （BCRP）-mediated resistant agents and to investigate clinical relationship between BCRP expression and drug resistance. Methods MTT assay was performed to filtrate BCRP-mediated resistant agents with BCRP expression cell model and to detect chemosensitivity of breast cancer tissue specimens to these agents. A high performance liquid chromatography （HPLC） assay was established, and was used to measure the relative dose of intracellular retention resistant agents. RT-PCR and immunohistochemistry （IHC） were employed to investigate the BCRP expression in breast cancer tissue specimens. Results MTT assay showed that the expression of BCRP increased with the increasing resistance of 5-fluorouracil （5-Fu）（P〈0.05, n=3） in the cell model, while HPLC assay indicated that the intracellular retention dose of 5-Fu was significantly correlated with the expression of BCRP （t=-0.897, P〈0.05, n=3）. A total of 140 breast cancer tissue specimens were collected. BCRP-positive expression was detected in forty-seven specimens by both RT-PCR and IHC. As shown by MTT assay subsequently, the resistance index （RI） of 47 BCRP-positive breast cancer tissue specimens to 5-Fu was 7-12 times as high as that of adjacent normal tissue samples. BCRP expression was related to 5-Fu resistance （R2=0.8124, P〈0.01）. Conclusion Resistance to 5-Fu can be mediated by BCRR Clinical chemotherapy for breast cancer patients can be optimized based on BCRP-positive expression.

关键词： Breast cancer resistance protein 5-fluorouracil Breast cancer Resistance Chemotherapy

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Data processing and initial results from the CE-3 Extreme Ultraviolet Camera

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Research in Astronomy and Astrophysics 2014年第12期14卷 1664-1673页

作者： jian-Qing Feng jian-jun liu Fei He Wei Yan Xin Ren Xu Tan Ling-Ping He Bo Chen Wei Zuo Wei-Bin Wen Yan Su Yong-Liao Zou Chun-Lai Li Key Laboratory of Lunar and Deep Space Exploration National Astronomical ObservatoriesChinese Academy of Sciences Changchun Institute of Optics Fine Mechanics and Physics Chinese Academy of Sciences

The Extreme Ultraviolet Camera （EUVC） onboard the Chang＇e-3 （CE-3） lander is used to observe the structure and dynamics of Earth＇s plasmasphere from the Moon. By detecting the resonance line emission of helium ions （He＋） at 30.4 nm, the EUVC images the entire plasmasphere with a time resolution of 10 min and a spatial resolution of about 0.1 Earth radius （RE） in a single frame. We first present details about the data processing from EUVC and the data acquisition in the commissioning phase, and then report some initial results, which reflect the basic features of the plas- masphere well. The photon count and emission intensity of EUVC are consistent with previous observations and models, which indicate that the EUVC works normally and can provide high quality data for future studies.

关键词： space vehicles: instruments: Extreme Ultraviolet Camera -- Earth: plas-masphere -- method: data processing

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Analysis of the geomorphology surrounding the Chang'e-3 landing site

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Research in Astronomy and Astrophysics 2014年第12期14卷 1514-1529页

作者： Chun-Lai Li Ling-Li Mu Xiao-Duan Zou jian-jun liu Xin Ren Xing-Guo Zeng Yi-Man Yang Zhou-Bin Zhang Yu-Xuan liu Wei Zuo Han Li Key Laboratory of Lunar and Deep Space Exploration National Astronomical ObservatoriesChinese Academy of Sciences

Chang＇e-3 （CE-3） landed on the Mare Imbrium basin in the east part of Sinus Iridum （19.51°W, 44.12°N）, which was China＇s first soft landing on the Moon and it started collecting data on the lunar surface environment. To better understand the environment of this region, this paper utilizes the available high-resolution topography data, image data and geological data to carry out a detailed analysis and research on the area surrounding the landing site （Sinus Iridum and 45 km×70 km of the landing area） as well as on the topography, landform, geology and lunar dust of the area surrounding the landing site. A general topographic analysis of the surrounding area is based on a digital elevation model and digital elevation model data acquired by Chang＇e-2 that have high resolution; the geology analysis is based on lunar geological data published by USGS; the study on topographic factors and distribution of craters and rocks in the surrounding area covering 4km^4km or even smaller is based on images from the CE-3 landing camera and images from the topographic camera; an analysis is done of the effect of the CE-3 engine plume on the lunar surface by comparing images before and after the landing using data from the landing camera. A comprehensive analysis of the results shows that the landing site and its surrounding area are identified as typical lunar mare with flat topography. They are suitable for maneuvers by the rover, and are rich in geological phenomena and scientific targets, making it an ideal site for exploration.

关键词： atlases -- methods: data analysis -- techniques: image processing --techniques: photometric

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Analytical solutions for constant-rate test in bounded confined aquifers with non-Darcian effect

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Journal of Groundwater Science and Engineering 2022年第4期10卷 311-321页

作者： Yi-jie Zong Li-hua Chen jian-jun liu Yue-hui liu Yong-xin Xu Fu-wan Gan Liang Xiao College of Civil Engineering and Architecture Guangxi UniversityNanning 530004China Guangxi Key Laboratory of Disaster Prevention and Engineering Safety Guangxi UniversityNanning 530004China Key Laboratory of Disaster Prevention and Structural Safety of Ministry of Education Guangxi UniversityNanning 530004China Department of Earth Sciences University of the Western CapeCape Town 8000South Africa

This paper proposes a simplified analytical solution considering non-Darcian and wellbore storage effect to investigate the pumping flow in a confined aquifer with barrier and recharge *** mathematical modelling for the pumping-induced flow in aquifers with different boundaries is developed by employing image-well theory with the superposition principle,of which the non-Darcian effect is characterized by Izbash’s *** solutions are derived by Boltzmann and dimensionless ***,the non-Darcian effect and wellbore storage are especially investigated according to the proposed *** results show that the aquifer boundaries have non-negligible effects on pumping,and ignoring the wellbore storage can lead to an over-estimation of the drawdown in the first 10 minutes of *** higher the degree of non-Darcian,the smaller the drawdown.

关键词： Non-Darcian effect Bounded aquifer Wellbore storage Izbash’s equation Analytical solution

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Identification of survival-associated biomarkers based on three datasets by bioinformatics analysis in gastric cancer

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World Journal of Clinical Cases 2023年第20期11卷 4763-4787页

作者： Long-Kuan Yin Hua-Yan Yuan jian-jun liu Xiu-Lian Xu Wei Wang Xiang-Yu Bai Pan Wang Department of Gastrointestinal Surgery Affiliated Hospital of North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina Sichuan Key Laboratory of Medical Imaging North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina

BACKGROUND Gastric cancer(GC)is one of the most common malignant tumors with poor prognosis in terms of advanced ***,the survival-associated biomarkers for GC remains *** To investigate the potential biomarkers of the prognosis of patients with GC,so as to provide new methods and strategies for the treatment of *** RNA sequencing data from The Cancer Genome Atlas(TCGA)database of STAD tumors,and microarray data from Gene Expression Omnibus(GEO)database(GSE19826,GSE79973 and GSE29998)were *** differentially expressed genes(DEGs)between GC patients and health people were picked out using R software(x644.1.3).The intersections were underwent between the above obtained co-expression of differential genes(co-DEGs)and the DEGs of GC from Gene Expression Profiling Interactive Analysis database,and Gene Ontology(GO)analysis,Kyoto Encyclopedia of Gene and Genome(KEGG)pathway analysis,Gene Set Enrichment Analysis(GSEA),Protein-protein Interaction(PPI)analysis and Kaplan-Meier Plotter survival analysis were performed on these *** Immunohistochemistry(IHC)database of Human Protein Atlas(HPA),we verified the candidate Hub *** With DEGs analysis,there were 334 co-DEGs,including 133 up-regulated genes and 201 down-regulated *** enrichment analysis showed that the co-DEGs were involved in biological process,cell composition and molecular function *** enrichment analysis suggested the co-DEGs pathways were mainly enriched in ECM-receptor interaction,protein digestion and absorption pathways,*** pathway analysis showed that co-DEGs mainly concentrated in cell cycle progression,mitotic cell cycle and cell cycle pathways,*** analysis showed 84 nodes and 654 edges for the *** survival analysis illustrated 11 Hub genes with notable significance for prognosis of patients were ***,using IHC database of HPA,we confirmed the above candidate Hub genes,and 10 Hub genes that associated with prognos

关键词： Gastric cancer Survival-associated biomarkers Bioinformatics analysis Hub genes

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