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基于两级分层优化的能源存储系统模型预测控制

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全球能源互联网 2025年第1期8卷 36-47页

作者：李阿勇李坚吴佳国网冀北电力有限公司北京市西城区100054

为了实现配电网的经济高效运行,提出了一种基于两级分层优化的能源存储系统模型预测控制方法。首先提出了一种字典优化方案,通过最小化变压器功率极限限制和飞轮能量损失来定义飞轮功率设定点;然后导出了表示飞轮功率损耗及其最大功率... 详细信息

为了实现配电网的经济高效运行,提出了一种基于两级分层优化的能源存储系统模型预测控制方法。首先提出了一种字典优化方案,通过最小化变压器功率极限限制和飞轮能量损失来定义飞轮功率设定点;然后导出了表示飞轮功率损耗及其最大功率的凸函数,并引入两级分层控制框架,从而处理预测误差和模型精度的方式操作变压器飞轮系统;最后通过仿真和实验结果验证了所提出的能量管理和控制方案在现实条件下提供调峰服务的有效性。

关键词：分层优化储能系统模型 FESS建模预测控制线性规划

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社会参与对中老年人认知衰弱的影响效应分析

现代预防医学 2025年第2期52卷 315-321页

作者：吴锦萍田函张妍吴炳义董惠玲周建裕山东第二医科大学管理学院山东第二医科大学护理学院

目的探讨社会参与对中老年人认知衰弱的影响，为提升或维持中老年人认知健康水平提供参考。方法选取2018年中国老年健康影响因素跟踪调查(CLHLS)数据中6 645名50岁以上中老年人作为研究对象，采用简易精神状态评价量表(MMSE)和衰弱指... 详细信息

目的探讨社会参与对中老年人认知衰弱的影响，为提升或维持中老年人认知健康水平提供参考。方法选取2018年中国老年健康影响因素跟踪调查(CLHLS)数据中6 645名50岁以上中老年人作为研究对象，采用简易精神状态评价量表(MMSE)和衰弱指数(FI)评价认知衰弱。采用多元logistic回归模型分析社会参与类型及强度对认知衰弱的影响。结果中老年人的家庭活动、个人活动、群体活动参与度越高，表现出的认知衰弱发生率越低；家庭活动高参与对轻度(OR=0.271,95%CI:0.228～0.321)、中度(OR=0.463,95%CI:0.361～0.592)和重度(OR=0.079,95%CI:0.043～0.146)认知衰弱的影响程度最高；女性中老年人在家庭活动高参与中对认知衰弱发生率起负向调节作用(OR=2.263,95%CI:1.579～3.244),城镇中老年人在群体活动中参与(OR=0.459,95%CI:0.289～0.727)和高参与(OR=0.490,95%CI:0.331～0.725)中对认知衰弱发生率起负向调节作用。结论提高中老年人对社会参与的积极性，尤其是家庭活动，对延缓认知衰弱水平的下降具有重要意义。

关键词：社会参与认知衰弱老年人

影响牙髓干细胞成骨及成牙本质分化的相关物理因素及作用机制

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中国组织工程研究 2025年第7期29卷 1531-1540页

作者：孙玉婷吴家媛张剑遵义医科大学口腔医学院贵州省遵义市563000

背景:牙髓干细胞是口腔颌面部组织工程中极具应用潜力的干细胞之一,较骨髓间充质干细胞具有采集方便、伦理问题少以及增殖分化潜能高等优势。目前,除了生物化学等因素外,物理刺激对于牙髓干细胞的成骨/成牙本质分化也起着关键性的作用... 详细信息

背景:牙髓干细胞是口腔颌面部组织工程中极具应用潜力的干细胞之一,较骨髓间充质干细胞具有采集方便、伦理问题少以及增殖分化潜能高等优势。目前,除了生物化学等因素外,物理刺激对于牙髓干细胞的成骨/成牙本质分化也起着关键性的作用。目的:综述影响牙髓干细胞成骨/成牙本质分化的相关物理因素以及可能涉及的信号传导通路作用机制,寻找影响其分化的最佳诱导条件。方法:检索PubMed和中国知网数据库,以“牙髓干细胞,成骨分化,成牙本质分化,低氧,机械力,激光,磁场,微重力”为中文检索词,以“dental pulp stem cells(DPSCs),osteogenesis differentiation,odontoblastic differentiation,hypoxia,mechanical force,laser therapy,magnetic fields,microgravity”为英文检索词,选取与影响牙髓干细胞成骨/成牙本质分化相关物理因素有关的79篇文献进行综述。结果与结论:(1)微环境中直接或间接的物理信号在调控牙髓干细胞定向分化方面展现出了广阔的应用前景。低氧、力学刺激(动静水压力、机械牵张力及剪切力等)、激光、微重力和磁场等相关物理因素对牙髓干细胞的影响以促进成骨/成牙本质分化为主,因口颌系统拥有复杂的力学环境,力学刺激是细胞环境改变的关键物理因素,同时也是组织工程的一个前沿领域,深入探讨牙髓干细胞对力学环境的响应为口腔疾病的诊断及治疗提供新思路。(2)因该领域比较“年轻”,相关因素涉及的设备参数尚未统一,相关结果存在不一致性,未能达成共识,之后应进一步探索及优化相关物理因素的最佳诱导参数及作用条件。(3)支架材料作为组织工程的三要素之一,在牙髓干细胞成骨/成牙本质分化方面也起到了促进作用,同时也推动了材料学的发展及临床技术的进步。(4)其中涉及到的信号通路有Notch,Wnt,MAPK等,关于物理刺激如何调控牙髓干细胞行为的相关生物学基础尚未明确,未来将进一步探究其具体作用机制,为物理因素影响下的牙髓再生及骨组织工程提供新思路。

关键词：牙髓干细胞成骨分化成牙本质分化物理因素力学因素信号通路干细胞组织工程

基于机器学习筛选猪活体肌内脂肪含量间接选育和构建预测模型的关键性状

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南京农业大学学报 2025年第1期48卷 161-170页

作者：吴建杨文孟孜查成万吴望军南京农业大学动物科技学院江苏南京210095

[目的]本研究旨在探究猪断奶重、屠宰前活体重、背膘厚等性状因素对猪肌内脂肪(intramuscular fat,IMF)含量的影响,确定影响猪IMF含量的关键性状因素。[方法]以805头皮特兰×[杜洛克×(长白×大白)]四元商品猪群为试验对象,记录性别,测... 详细信息

[目的]本研究旨在探究猪断奶重、屠宰前活体重、背膘厚等性状因素对猪肌内脂肪(intramuscular fat,IMF)含量的影响,确定影响猪IMF含量的关键性状因素。[方法]以805头皮特兰×[杜洛克×(长白×大白)]四元商品猪群为试验对象,记录性别,测定初生重、断奶重、屠宰前活体重和IMF含量等14个性状,然后通过相关性分析从14个性状中初步筛选出影响IMF含量的性状因素,再通过随机森林模型评估各性状因素对IMF含量影响的重要性,进一步通过LASSO回归和逐步回归筛选出影响IMF含量的关键性状因素;在此基础上,利用广义线性模型(generalized linear model,GLM)分析关键性状因素不同水平对IMF含量的影响。[结果]相关性分析结果显示,猪IMF含量与断奶重(r=0.13, P0.05)。胸腰椎结合处背膘厚大于26 mm组的平均IMF含量(2.73%)显著高于其他背膘厚组(P0.05)。[结论]本研究通过机器学习确定了性别、断奶重、屠宰前活体重和胸腰椎结合处背膘厚4个与IMF含量显著相关的活体可测定性状,并发现平均IMF含量随着屠宰前活体重和胸腰椎结合处背膘厚的增加呈明显的上升趋势。

关键词：猪肌内脂肪间接选择模型构建机器学习活体可测定性状

不同类型油藏非均相驱均衡驱替方式及效果评价

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工程科学学报 2025年第3期47卷 419-429页

作者：吴德君侯健刘丽杰周康安志斌中国石化胜利油田分公司勘探开发研究院东营257000 中国石油大学(华东)石油工程学院青岛266580 山东科技大学能源与矿业工程学院青岛266590

非均相驱协同矿场调整措施在孤岛油田中一区Ng3单元取得了良好的降水增油效果.然而,由于实际地层非均质性复杂、层间井网部署的差异及不同层位化学剂注入量不同,非均相驱在动用平面和纵向分布剩余油的过程中会相互影响,很难明确不同方... 详细信息

非均相驱协同矿场调整措施在孤岛油田中一区Ng3单元取得了良好的降水增油效果.然而,由于实际地层非均质性复杂、层间井网部署的差异及不同层位化学剂注入量不同,非均相驱在动用平面和纵向分布剩余油的过程中会相互影响,很难明确不同方式均衡驱替贡献力度,难以阐明不同类型剩余油的动用机制.为此,本文采用数值模拟方法,基于目标区块实际地层参数,建立了五种不同类型剩余油油藏机理模型,通过受效剩余油分布、洗油效率、波及系数、平面含水饱和度变异系数及纵向吸水不均衡系数等指标,评价了非均相驱平面及纵向均衡驱替效果,阐明了剩余油动用机制.数值模拟研究表明,非均相驱协同井网调整或分层配注等矿场调整措施,能最大程度扩大波及、提升均衡驱替效果.针对不同类型剩余油油藏,明确了均衡驱替方式贡献力度及实施优先级,实际应用时应根据油藏类型和矿场实施条件,选取适宜的均衡驱替方式.本研究为矿场非均相驱动用不同类型剩余油提供了合理的解释,对非均相驱在矿场不同类型油藏的进一步推广应用提供参考.

关键词：非均相驱均衡驱替剩余油动用数值模拟井网调整分层配注

饲养方式对牦牛肌肉脂肪酸组成和挥发性风味物质的影响研究进展

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动物营养学报 2025年第1期37卷 87-100页

作者：王莉魏健吴斌王玉涛喀什大学生命与地理科学学院新疆帕米尔高原生物资源与生态重点实验室喀什844000 石河子大学石河子832003

肌肉脂肪酸组成和挥发性风味物质是呈现牦牛肉质的关键指标。饲养方式(饲粮组成)对牦牛肌肉脂肪酸组成有较大影响,而肌肉脂肪酸组成差异则是影响其挥发性风味物质种类、组成及含量的主要直接因素。本文主要总结分析了牦牛肉脂肪酸对挥... 详细信息

肌肉脂肪酸组成和挥发性风味物质是呈现牦牛肉质的关键指标。饲养方式(饲粮组成)对牦牛肌肉脂肪酸组成有较大影响,而肌肉脂肪酸组成差异则是影响其挥发性风味物质种类、组成及含量的主要直接因素。本文主要总结分析了牦牛肉脂肪酸对挥发性风味物质形成的作用及饲养方式对牦牛肌肉脂肪酸组成及挥发性风味物质的影响效应,旨在为牦牛肉品质调控提升及高质化利用提供参考借鉴。

关键词：饲养方式牦牛肉脂肪酸组成挥发性风味物质

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DNA2 knockout aggravates cerebral ischemia/reperfusion injury by reducing postsynaptic Homer1a

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Zoological Research 2025年第01期 87-102页

作者： Ting Ma Yu-Meng Li Peng-Yu Ren Shi-Quan Wang Xiang-Long Liu Wen-Bo Lv wu-Gang Hou Wen-Qiang Zuo Wei-Qiang Lin jian Sima An-Qi Geng Laboratory of Aging Neuroscience and Neuropharmacology School of Basic Medicine and Clinical Pharmacy China Pharmaceutical University Research & Development Institute of Northwestern Polytechnical University in Shenzhen Xi'an Key Laboratory of Stem Cell and Regenerative Medicine Xi'an Key Laboratory of Special Medicine and Health Engineering Institute of Medical Research Northwestern Polytechnical University Sanhang Institute for Brain Science and Technology Northwestern Polytechnical University Department of Anesthesiology and Perioperative Medicine Xijing Hospital Fourth Military Medical University College of Pharmacy Shaanxi University of Chinese Medicine International Institutes of Medicine Fourth Affiliated Hospital School of Medicine Zhejiang University

DNA2, a multifunctional enzyme with structure-specific nuclease, 5'-to-3' helicase, and DNA-dependent ATPase activities, plays a pivotal role in the cellular response to DNA damage. However, its involvement in cerebral ischemia/reperfusion(I/R) injury remains to be *** study investigated the involvement of DNA2 in cerebral I/R injury using conditional knockout(cKO) mice(Nestin-Cre) subjected to middle cerebral artery occlusion(MCAO), an established model of cerebral I/R. Results demonstrated a gradual up-regulation of DNA2 expression,peaking at 72 h post-MCAO. Notably, DNA2 cKO mice exhibited more pronounced brain injury, neurological deficits, and neuronal apoptosis within the penumbra following MCAO. Additionally, DNA2 expression was elevated in an oxygen-glucose deprivation/reoxygenation(OGD/R) cell culture model, and DNA2 knockdown(KD)exacerbated neuronal apoptosis and oxidative *** analysis of ischemic penumbra tissues via RNA sequencing revealed significant down-regulation of Homer1 in DNA2 cKO mice. Furthermore, in vitro experiments demonstrated that overexpression of Homer1a ameliorated DNA2 KD-induced neuronal apoptosis. Collectively, these findings demonstrate that DNA2 deficiency exacerbates cerebral I/R injury through the down-regulation of Homer1a, highlighting a novel regulatory axis in ischemic neuroprotection.

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Prevalence of Helicobacter pylori infection in Chinese military personnel:A cross-sectional,multicenter-based study

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World Journal of Gastroenterology 2025年第3期31卷 42-49页

作者： Han-Chen Min Chun-Yan Zhang Fang-Yu Wang Xiao-Hui Yu Shan-Hong Tang Hong-wu Zhu Ya-Gang Zhao Ji-Luo Liu jian Wang Jing-Han Guo Xiao-Mei Zhang Yun-Sheng Yang Chinese People’s Liberation Army Medical School Chinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology and Hepatology The First Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Sixth Healthcare Department The Second Medical CenterChinese People’s Liberation Army General HospitalBeijing 100853China Department of Gastroenterology The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation ArmyLanzhou 730050Gansu ProvinceChina Department of Gastroenterology General Hospital of Western Theater CommandChengdu 610011Sichuan ProvinceChina Department of Gastroenterology General Hospital of Southern Theater CommandGuangzhou 510010Guangdong ProvinceChina Department of Epidemiology Naval Medical UniversityShanghai 200433China School of Medicine Nankai UniversityTianjin 300071China National Clinical Research Center for Geriatric Diseases Chinese People’s Liberation Army General HospitalBeijing 100853China

BACKGROUND Helicobacter pylori(***)infection is a prevalent disease encountered in military internal medicine and recognized as the main cause of dyspepsia,gastritis,and peptic ulcer,which are common diseases in military *** guidelines in China state all patients with evidence of active infection with *** are offered ***,the prevalence of *** infection and its regional distribution in the military population remain unclear,which hinders effective prevention and treatment *** the prevalence of *** infection in the military population will aid in the development of customized strategies to better manage this infectious *** To investigate the prevalence of *** infection in the Chinese military population in different geographic *** This multicenter,retrospective study included 22421 individuals from five tertiary hospitals located in north,east,southwest,and northwest cities of *** infection was identified using the urea breath test,which had been performed between January 2020 and December *** Of the 22421 military service members,7416(33.1%)were urea breath *** highest prevalence of *** was in the 30-39 years age group for military personnel,with an infection rate of 34.9%.The majority of infected subjects were younger than 40-years-old,accounting for 70.4%of the infected *** individuals serviced in Lanzhou and Chengdu showed a higher infection prevalence than those in Beijing,Nanjing,and Guangzhou,with prevalence rates of 44.3%,37.9%,29.0%,31.1%,and 32.3%,*** *** infection remains a common infectious disease among military personnel in China and has a relatively high prevalence rate in northwest China.

关键词： Helicobacter pylori Prevalence Military personnel Urea breath test Multicenter study

Inclusions modification by rare earth in steel and the resulting properties: A review

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Journal of Rare Earths 2024年第3期42卷 431-445,I0001页

作者： Xiaoqiang Wang Zhiwei wu bing Li Wenxiong Chen Jun Zhang jian Mao College of Materials Science and Engineering Sichuan UniversityChengdu610065China Chengdu Advanced Metal Materials Industry Technology Research Institute Co. Ltd.Chengdu610303China State Key Laboratory of Metal Material for Marine Equipment and Application Anshan114009China

Rare earth(RE) elements are excellent modifiers for non-metallic inclusions that inevitably appear in steel and affect steel properties. This paper reviews the research status of inclusions modification by RE elements and the changes it cause on steel properties. First, the inclusion changes caused by RE modification are described. Generally, after adding pure RE, the main evolution of inclusions occurs as M →M + RE-Al-O → RE-Al-O + RE_(2)O_(2)S → RE_(2)O_(2)S + RE—S/RE_(2)O_(2)S + RE-O with an increase in the RE content(M represents the inclusions before RE addition). The type of final inclusion obtained after RE modification is related to the relative contents of S and O in the steel. Moreover, fine, regular, and uniformly distributed inclusions can be obtained with appropriate RE addition. However, the effectiveness of inclusions modification by adding both RE and non-RE elements is closely related to the order of their addition. Second, the applications and advantages of thermodynamic calculations in the study of RE-modified inclusions are introduced. Third, the changes in the corrosion resistance, impact properties,and other properties of steel caused by the modification of inclusions by RE are reviewed. Finally, the perspectives and trends of inclusions modified by RE elements in the steel industry are presented.

关键词： Rare earths Inclusions Modification Thermodynamic calculation Properties change