检索结果-南通市图书馆

Chemical Research in Chinese Universities 2002年第3期18卷 287-289页

作者： LUO Xu yang zhao jian zhang LIN Ying jie LIU Zai qun College of Chemistry Jilin UniversityChangchun 130023P.R.China

The hemolysis of human red blood cells was initiated by a water soluble free radical initiator, 2,2′ azobis (2 amidinopropane hydrochloride)(AAPH), at 37 ℃ in phosphate buffered saline(pH=7.4). The respective addition of 1 [ N (o hydroxybenzylidene)amino]tetradecane(TDCA), 1,2 di[ N (o hydroxybenzylidene)amino]cyclohexane(DACH), 4 [ N (o hydroxybenzylidene)amino]benzoic acid(PABA), 4 nitro[ N (o hydroxybenzylidene)]aniline(APNA) or N (o hydroxybenzylidene)aniline(APA) can all prolong the inhibition period of hemolysis, indicating that the above Schiff bases play an antioxidative role in free radical induced hemolysis. It can be concluded that Schiff base with an alkyl group or a conjugated system in the molecule protect red blood cells against free radical induced hemolysis efficiently. This information may be useful for antioxidant drug design.

关键词： Red blood cell Hemolysis Schiff base Free radical

Synthesis and Crystal Structure of [Cd(NBA)(μ_3-OH)(4,4′-bipy)_(1/2)]_n

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2007年第8期26卷 917-919页

作者： SHEN Yi-Cheng zhang jian LI zhao-Ji zhang Lei YIN Pei-Xiu YAO Yuan-Gen State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter The Chinese Academy of Sciences Fuzhou Fujian 350002 China

A new cadmium polymer [Cd（NBA）（μ3-OH）（4,4＇-bipy）1/2]n 1 （NBA=m-nitrobenzoic acid and 4,4＇-bipy=4,4-bipyridine） has been synthesized by hydrothermal reaction. Its structure was determined by single-crystal X-ray diffraction method, and characterized by elemental analysis and IR spectrum. The crystal is of monoclinic, space group C2/c, with a=15.6912（9）, b=25.9394（15）, c=6.7332（4）A, β=114.7700（10）°, V=2488.4（3）A^3, C12H9CdN2O5, Mr=373.61, Z=8, Dc=1.995 g/cm^3,μ=1.776 mm^-1, F（000）=1464, R=0.0411 and wR=0.1128 for 2130 observed reflections （I 〉 2σ（I））.X-ray diffraction studies reveal that the compound features a layered structure, in which 4,4＇-bipy ligands bridge Z type of double chains [Cd（μ3-OH）]n and NBA ligands locate at the two sides of the layer. The π-π interactions between the benzene rings of NBA ligands of two adjacent layers lead to the 3D framework.

关键词： cadmium polymer 4 4'-bipyridine m-nitrobenzoic acid crystal structure

Disease Risks of Childhood Obesity in China

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2005年第6期18卷 401-410页

作者： YAN-PING LI XIAO-GUANG YANG FENG-YING ZHAI jian-HUA PIAO WEN-HUA zhao jian zhang GUAN-SHENG MA National Institute for Nutrition and Food Safety Chinese Center for Disease Control and Prevention 29 Nanwei Road Beijing 100050 China

Objective To estimate the relative risks of dyslipidemia, hypertension, diabetes mellitus, and metabolic syndromes among overweight and obese Chinese children compared with their normal weight counterparts. Methods Overweight and obesity were defined by age- and sex-specific BMI classification reference for Chinese children and adolescents. Pediatric metabolic syndrome （MetS） and each risk factor for MetS were defined using the criteria for US adolescents. Definition of hyper-TC, LDL, and dyslipidemia for adults was applied as well. General linear model factor analysis and chi-square test were used to compare the difference in metabolic indicators among normal weight, overweight, and obese groups. Multiple logistic regression analysis was performed to estimate the odds ratio of metabolic abnormalities between obesity, overweight, and normal weight children, after adjustment for living area, family economic level, age, sex, and daily exercise time and TV watching time, as well as different dietary indices in the model. Results Significant increases in blood lipids, glucose, and blood pressure were found among overweight and obese children as compared with their counterparts with normal weight. By applying WGOC-recommended BMI classification, the risks for hypertriglyceridemia, low HDL and dyslipidemia among overweight children were 1.9, 1.4, and 1.5 times, and was 3.3, 1.5, and 1.8 times among obese groups compared to their counterparts with normal weight after adjustment for age, sex, region, socioeconomic status, physical activity, and dietary intakes. The overweight and obese children （15-17.9 years） had a high-risk of developing hypertension, which was 2.3 and 2.9 times higher than their counterparts with normal weight. Above 90% obese adolescents had abdominal obesity, while less than 1% normal weight ones had abdominal obesity. No obese adolescents were free from any risk factors for MetS, while 36.9% of normal weight adolescents were from the risk factors. 83.

关键词： Chinese obese children Metabolic syndrome (MetS) Hypertension Lipids Relative risk

Chemoselective Catalytic Hydrogenation of α,β-Unsaturated Ketones and α,β-Unsaturated Carboxylic Esters

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 1998年第2期14卷 17-22页

作者： zhang Jing-wen zhao jian-zhang zhang Xiao-long jianG Yu-lin MA Xiu-li SUN Yun-xiu jianG Wen-pu LI Yao-xian XU Zhi-luo Department of Chemistry Jilin UniversityChangchun130023

The effect of catalysts P-2 00-Ni(Nickel boride) and P-2 00-Ni-M(M: Co, Fe, Cu, Sn), prepared by adopting a modified recipe, on the chemoselective hydrogenation of carbon carbon double bonds in α,β- unsaturated ketones, and the activity of catalysts P-1.80-Ni, P-2 00-Ni or P-1.80(2 00) -Ni-M(M: Pd, Co, Cu) in the selective hydrogenation of carbon carbon double bonds in α,β-unsaturated carboxylic esters, were investigated systematically. According to the experimental results, the selectivities of these catalysts toward the hydrogenation of the carbon carbon double bonds of α,β-unsaturated keones or α,β-unsaturated carboxylic esters are 96%—100% or 100%, respectively.

关键词： α β-Unsaturated ketone Nickel boride α β-Unsaturated carboxylic ester

Deceptive jamming discrimination based on range-angle localization of a frequency diverse array

在线全文

学校读者我要写书评

暂无评论

Frontiers of Information Technology & Electronic Engineering 2017年第9期18卷 1437-1446页

作者： zhao-jian zhang Jun-wei XIE Chuan SHENG Zhun TANG Air and Missile Defense College Air Force Engineering University Xi 'an 710051 China

We propose a method to suppress deceptive jamming by frequency diverse array （FDA） in radar electronic coun- termeasure environments. FDA offers a new range-angle-dependent beam pattern through a small frequency increment across elements. Due to the coupling between the angle and range, a mismatch between the test angle and physical angle occurs when the slant range on which the beam focuses is not equal to the slant range of the real target. In addition, the range of the target can be extracted by sum-difference beam except for time-delay testing, because the beam provides a range resolution in the FDA that cannot be deceived by traditional deceptive jamming. A strategy of using FDA to transmit two pulses with zero and nonzero frequency increments, respectively, is proposed to ensure that the angle of a target can be obtained by FDA. Moreover, the lo- calization performance is examined by analyzing the Cramer-Rao lower bound and detection probability. Effectiveness of the proposed method is confirmed by simulation results.

关键词： Frequency diverse array (FDA) Deceptive jamming Range-angle coupling Sum-difference beam Double-pulse

Identification of Novel Stress-responsive Transcription Factor Genes in Rice by cDNA Array Analysis

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2006年第10期48卷 1216-1224页

作者： Cong-Qing Wu Hong-Hong Hu Ya Zeng Da-Cheng Liang Ka-Bin Xie jian-Wei zhang zhao-Hui Chu Li-Zhong Xiong National Key Laboratory of Crop Genetic Improvement National Plant Gene Research Center Huazhong Agricultural University Wuhan 430070 China

Numerous studies have shown that array of transcription factors has a role in regulating plant responses to environmental stresses. Only a small portion of them however, have been Identified or characterized. More than 2 300 putative transcription factors were predicted In the rice genome and more than half of them were supported by expressed sequences. With an attempt to Identify novel transcription factors involved in the stress responses, a cDNA array containing 753 putative rice transcription factors was generated to analyze the transcript profiles of these genes under drought and salinity stresses and absclsic acid treatment at seedling stage of rice. About 80% of these transcription factors showed detectable levels of transcript in seedling leaves. A total of 18 up-regulated transcription factors and 29 down-regulated transcription factors were detected with the folds of changes from 2.0 to 20.5 in at least one stress treatment. Most of these stress-responsive genes have not been reported and the expression patterns for five genes under stress conditions were further analyzed by RNA gel blot analysis. These novel stress-responsive transcription factors provide new opportunities to study the regulation of gene expression In plants under stress conditions.

关键词： abiotic stress cDNA array Oryza sativa transcription factor

Synthesis of Enantiom eric Planar Square Ni^(2+) -and Cu^(2+) -Schiff Base Com plexes

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 1999年第3期15卷 248-252页

作者： zhao jian-zhang WANG Shu-gang WANG Xu LIU Ju-zheng QIAO Xiao-guang LI Yao-xian WANG Hua Department of Chemistry Jilin UniversityChangchun 130023P.R.China Third Clinical College&China Japan Union Hospital of Norman Bethune Unviersity of Me dical Sciences Changchun 130023P.R.China

Enantiomeric four chelated planar square schiff base Cu 2+ and Ni 2+ complexes were synthesized using ( 1R,trans ) and ( 1S,trans) N,N  bis(2 hydroxyphenyl methylene) 1,2 diaminocyclohexane. The chirality could not be shown by usual UV Vis spectra. The intrinsic chiral difference of the enantiomeric complexes can be displayed by circular dichroism(CD) spectra. The Cotton effect of every polarlight sensitive absorption of one enantiomer will be the opposite of that of the other enantiomer. It was found that no tetrahedron form exists for Ni 2+ complexes, which was determined with UV Vis spectra and Electron Paramagnetic Resonance(EPR) measures.

关键词： Chiral transition metal schiff base complex Circular dichroism(CD) Enantiomeric

Transforming waste particles into valuable adsorbents via amyloid-mediated molecular engineering

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第1期68卷 317-328页

作者： Qingmin Yang jian zhao Yujia zhang Xingyu Zhou Hao Ren Bowen Hu Zhongli Lei Lixin Chen Peng Yang School of Material and Chemical Engineering Bengbu University Anhui Provincial Engineering Laboratory of Silicon-Based Materials School of Chemistry and Chemical Engineering Northwestern Polytechnical University Key Laboratory of Applied Surface and Colloid Chemistry Ministry of Education School of Chemistry and Chemical EngineeringShaanxi Normal University Xi'an Key Laboratory of Polymeric Soft Matter School of Chemistry and Chemical Engineering Shaanxi Normal University International Joint Research Center on Functional Fiber and Soft Smart Textile School of Chemistry and Chemical EngineeringShaanxi Normal University

The high-value utilization of industrial solid waste using a facile and eco-friendly process is of great interest and significance in reducing environmental pollution and developing a green circular economy. Herein, we propose an amyloid-mediated molecular engineering strategy to transform particulate waste into valuable adsorbents for metal ions. Our method has the advantage of aqueous solution fabrication under mild conditions without the use of high-temperature hydrothermal methods and toxic chemical reagents. Amyloid-mediated molecular engineering manipulates the phase transition of bovine serum albumin(BSA)on particulate waste surfaces, resulting in a remarkable ～3.1 times improvement in the adsorption capacity of fly ash, a typical industrial solid waste for gold ions after modification with the phase-transitioned BSA(PTB). The resultant adsorption ability was 69–1,980 times higher than those of conventional and emerging adsorbent materials such as ion exchange resins, activated carbon(AC), covalent organic frameworks(COFs), and metal-organic frameworks(MOFs). We further demonstrated the application of our PTB-modified materials in the recovery of precious metals from low-grade gold ore and electronic waste leachates. Consequently, this strategy could increase the value of waste materials nearly 27 times. In addition, this method is generally extendable to other conventional industrial adsorbents such as resin, clay, and Al2O3, and enhances their adsorption capabilities at least twofold. Overall, this work provides a simple and green approach for improving the adsorption performance of solid particles, and is expected to develop into a universal strategy for transforming waste particles into high-value-added products.

关键词： amyloid-like protein aggregates surface engineering fly ash solid waste adsorption

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan zhao Yidan zhang Xin Liu jian zhang Ya Gao Shuyue Li Cui Chang Xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

An Efficient System TiCl_4-Al for the Homocoupling Reaction of Aromatic Aldehydes

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2000年第4期16卷 320-323页

作者： LI Ting-you, WANG Li-ping, CUI Wei, zhao jian-zhang and WANG Zong-mu (College of Life Science, Jilin University, Changchun 130023, P. R. China) 吉林大学吉林长春 130023

The reduction of TiCl4(THF)2 with Al in CH2Cl2 gave a green solution of [Ti2(μ-Cl)2Cl4· (THF)4] (1) which was found to promote the reductive homocoupling of aromatic aldehydes to yield symmetrical 1, 2-diols with hi... 详细信息

关键词： Pinacol coupling reaction Aromatic aldehyde Diastereoselectivity