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Effects of ulinastatin combined with dexmedetomidine on cognitive dysfunction and emergence agitation in elderly patients who underwent total hip arthroplasty

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World Journal of Psychiatry 2024年第1期14卷 26-35页

作者： Qi-Fan Huo Li-Juan Zhu jian-wei guo Yan-An jiang Jing Zhao Department of Anesthesiology Shaanxi Provincial People’s HospitalXi’an 710068Shaanxi ProvinceChina

BACKGROUND With the continuous growth of the modern elderly population,the risk of fracture *** fracture is a common type of fracture in older *** hip arthroplasty(THA)has significant advantages in relieving chronic pain and promoting the recovery of hip joint *** To investigate the effect of ulinastatin combined with dexmedetomidine(Dex)on the incidences of postoperative cognitive dysfunction(POCD)and emergence agitation in elderly patients who underwent *** A total of 397 patients who underwent THA from February 2019 to August *** conducted a three-year retrospective cohort study in Shaanxi Provincial People’s *** demographic data were obtained from the electronic medical record *** collected preoperative,intraoperative,and postoperative *** hundred twenty-nine patients who were administered Dex during the operation were included in the Dex *** hundred fifty patients who were intravenously injected with ulinastatin 15 min before anesthesia induction were included in the ulinastatin *** hundred eighteen patients who were administered ulinastatin combined with Dex during the operation were included in the Dex+ulinastatin *** patients’perioperative conditions,hemodynamic indexes,postoperative Mini-Mental State Examination(MMSE)scores,Ramsay score,incidence of POCD,and serum inflammatory cytokines were *** There was a significant difference in the 24 h visual analogue scale score among the three groups,and the score in the Dex+ulinastatin group was the lowest(P<0.05).Compared with the Dex and ulinastatin group,the MMSE scores of the Dex+ulinastatin group were significantly increased at 1 and 7 d after the operation(all P<0.05).Compared with those in the Dex and ulinastatin groups,incidence of POCD,levels of serum inflammatory cytokines in the Dex+ulinastatin group were significantly decreased at 1 and 7 d after the operation(all P<0.05).The observer’s assessment of th

关键词： Ulinastatin Dexmedetomidine Postoperative cognitive dysfunction Inflammatory cytokines Total hip arthroplasty

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PPA复合改性对沥青-集料黏附及其水稳定性影响研究

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中国公路学报 2024年第6期37卷 317-330页

作者：周育名张凯郭云龙岳浩王迪彭竹仪刘朝晖魏建国长沙理工大学道路结构与材料交通行业重点实验室湖南长沙410114 长沙理工大学交通运输工程学院湖南长沙410114 江苏东交智控科技集团股份有限公司江苏南京210046 山东高速交通建设集团有限公司山东济南250014 渥太华大学土木工程学院渥太华K1N 6N5

为探究多聚磷酸(PPA)对沥青-集料之间黏附及其水稳定性的影响,提出了以基质沥青、PPA改性沥青、SBS/PPA和SBR/PPA复合改性沥青与石灰岩、玄武岩和花岗岩集料组合的沥青混合料设计方案。采用分子动力学模拟方法,构建沥青-集料界面模型,... 详细信息

为探究多聚磷酸(PPA)对沥青-集料之间黏附及其水稳定性的影响,提出了以基质沥青、PPA改性沥青、SBS/PPA和SBR/PPA复合改性沥青与石灰岩、玄武岩和花岗岩集料组合的沥青混合料设计方案。采用分子动力学模拟方法,构建沥青-集料界面模型,并通过原子力显微镜(AFM)、接触角试验、动态剪切流变试验(DSR)以及浸水马歇尔试验和冻融劈裂试验探究了PPA掺加后对沥青-集料黏附及其水稳定性的影响。结果表明:随着PPA改性剂的添加,沥青表面自由能显著增大,沥青与集料间黏附功提高,交互能力增强,沥青混合料的水稳定性更优;通过3种集料的试验结果对比,发现碱性集料对改性沥青-集料的黏附与水稳定性改善效果更好;PPA加入后,使SBS、SBR聚合物改性沥青与集料间的黏附功略有下降,但综合水稳定性得到明显改善;因此,推荐采用SBS/PPA复合改性沥青及石灰岩集料进行混合料组合设计,此组合可以得到最佳的黏附性及水稳定性。

关键词：路面工程多聚磷酸改性沥青试验分析黏附性能水稳定性沥青-集料界面

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数字普惠金融与我国农村居民消费研究——基于信贷供给的中介效应分析

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武汉理工大学学报（社会科学版） 2024年第1期37卷 88-95,124页

作者：姜慧魏建国武汉理工大学经济学院武汉430070

基于2011-2021年省级面板数据,构建双向固定效应模型和中介效应模型,以此探究数字普惠金融对我国农村居民消费规模、消费结构的影响,并对农村地区的土地制度、农业生产、农户创业、产业结构进行分析。研究结果表明:(1)数字普惠金融显著... 详细信息

基于2011-2021年省级面板数据,构建双向固定效应模型和中介效应模型,以此探究数字普惠金融对我国农村居民消费规模、消费结构的影响,并对农村地区的土地制度、农业生产、农户创业、产业结构进行分析。研究结果表明:(1)数字普惠金融显著提高了我国农村居民的消费规模,但这种作用存在明显区域异质性,检验表明其作用在东部地区更加显著;(2)数字普惠金融能够改善农村居民消费结构;(3)数字普惠金融的发展,能够通过缓解信贷约束这一途径促进农村居民消费。最后提出了加强数字普惠金融发展助力农村消费的建议,包括制定农村数字普惠金融发展战略,强化数字普惠金融助农理念,加强数字化基础设施建设,建立多元化数字推进机制等。

关键词：数字普惠金融农村居民消费中介效应信贷支持

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王书臣教授辨证治疗肺痿经验

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世界中西医结合杂志 2024年第2期19卷 266-269,301页

作者：韦建国易亮王书臣中国中医科学院西苑医院急诊科北京100091

特发性肺间质纤维化(Idiopathic pulmonary fibrosis, IPF)已成为国际化难题,患者多病情进展迅速、生活质量低下、生存期短,单用西医激素和免疫抑制剂或细胞因子抑制剂治疗,难以延缓或逆转肺纤维化的进展,同时诸多药物反应限制其应用。... 详细信息

特发性肺间质纤维化(Idiopathic pulmonary fibrosis, IPF)已成为国际化难题,患者多病情进展迅速、生活质量低下、生存期短,单用西医激素和免疫抑制剂或细胞因子抑制剂治疗,难以延缓或逆转肺纤维化的进展,同时诸多药物反应限制其应用。通过中医辨证论治结合现代中药药理,王书臣教授对特发性肺间质纤维化的中医病名、病因病机及治疗原则形成了自己独特的见解,认为重症患者当以“肺痿”命名更佳,提出“治肺痿如治中风”“治肺痿当祛风”“治痿当兼顾脾胃”“肺肾同治”等观点,临床中用于患者治疗,疗效确切,为提高患者生活质量提供了宝贵经验。

关键词：特发性肺间质纤维化肺痿药理治疗体会验案

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Unraveling the macroevolution of horseshoe bats(Chiroptera: Rhinolophidae: Rhinolophus)

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Zoological Research 2023年第1期44卷 169-182页

作者： wei-jian guo Yi Wu Kai He Yi-Bo Hu Xiao-Yun Wang Wen-Hua Yu Key Laboratory of Conservation and Application in Biodiversity of South China School of Life SciencesGuangzhou UniversityGuangzhouGuangdong 510000China CAS Key Laboratory of Animal Ecology and Conservation Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China

Unraveling the diversification mechanisms of organisms is a fundamental and important macroevolutionary question regarding the diversity,ecological niche, and morphological divergence of life. However, many studies have only explored diversification mechanisms via isolated factors. Here,based on comparative phylogenetic analysis, we performed a macroevolutionary examination of horseshoe bats(Chiroptera: Rhinolophidae:Rhinolophus), to reveal the inter-relationships among diversification, intrinsic/extrinsic factors, and climatic ecological niche characteristics. Results showed a general slowing trajectory during diversification, with two dispersal events from Asia into Southeast Asia and Africa playing key roles in shaping regional heterogeneous diversity. Morphospace expansions of the investigated traits(e.g., body size,echolocation, and climate niche) revealed a decoupled pattern between diversification trajectory and trait divergence, suggesting that other factors(e.g., biotic interactions) potentially played a key role in recent diversification. Based on ancestral traits and pathway analyses, most Rhinolophus lineages belonging to the same region overlapped with each other geographically and were positively associated with the diversification rate, implying a competitive prelude to speciation. Overall, our study showed that multiple approaches need to be integrated to address diversification history. Rather than a single factor, the joint effects of multiple factors(biogeography, environmental drivers, and competition) are responsible for the current diversity patterns in horseshoe bats, and a corresponding multifaceted strategy is recommended to study these patterns in the future.

关键词： Diversification Rhinolophus Historical biogeography Abiotic/Biotic factors Climatic niche characteristics Competition

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Processing of a low-costγ-γ'NiPtAl coating with improved oxidation resistance

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Rare Metals 2024年第6期43卷 2832-2841页

作者： Yan jiang Liang-Liang wei jian He Hong-Bo guo School of Materials Science and Engineering Beihang UniversityBeijing 100191China Key Laboratory of High-Temperature Structural Materials and Protective Coatings Ministry of Industry and Information TechnologyBeihang UniversityBeijing 100191China

A novelγ-γ'(Ni solid solution—Ni_(3)Al)NiPtAl coating was produced on advanced single-crystal(SC)superalloy N5 by electroplating of a thin Pt coating with~3μm in thickness followed by heat treatment at 1000℃in *** comparison,a traditionalγ-γ'NiPtAl coating was also produced by electroplating of a thick Pt coating with~6μm in thickness followed by heat treatment at 1100℃in *** novel coating has a mass gain of~0.5 mg·cm^(-2)after 100 h 1-h cyclic oxidation at 1150℃,showing better oxidation resistance than the traditional *** oxide scale mostly consisting ofα-Al_(2)O_(3)grew on the novel coating because the element Cr from the SC alloy substrate contributes to the formation ofα-Al_(2)O_(3).Pt content in the novel coating has significant effect on the oxidation *** optimized Pt content in the coating is about 16 at%,which is helpful to reduce the diffusion of harmful elements from the substrate into the coating but also to reduce the cost of the coating.

关键词： γ-γ'NiPtAl coating Platinum Oxidation Al_(2)O_(3) Superalloy

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Harnessing data using symbolic regression methods for discovering novel paradigms in physics

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Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 1-11页

作者： jianyang guo Wan-jian Yin College of Energy Soochow Institute for Energy and Materials Innovations(SIEMIS)Jiangsu Provincial Key Laboratory for Advanced Carbon Materials and Wearable Energy TechnologiesSoochow UniversitySuzhou 215006China Shanghai Qi Zhi Institute Shanghai 200232China Light Industry Institute of Electrochemical Power Sources Soochow UniversitySuzhou 215006China

In recent years,machine-learning methods have profoundly impacted research in the interdisciplinary fields of ***,most machine-learning models lack interpretability,and physicists doubt the credibility of their conclusions because they cannot be combined with prior physical ***,this review focuses on symbolic regression,which is an interpretable machine-learning ***,the relevant concepts of machine learning are introduced in conjunction with ***,we provide an overview of symbolic regression ***,the recent directions for the application of symbolic regression methods in different subfields of physics are outlined,and an overview of the ways in which the applications of symbolic regression have evolved in the realm of physics is *** major aim of this review is to introduce the basic principles of symbolic regression and explain its applications in the field of physics.

关键词： machine learning genetic programming symbolic regression

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Progress in preparation of AlN-reinforced magnesium matrix composites:A review

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China Foundry 2024年第1期21卷 1-10页

作者： Lu Chen Shu-lin Lü Di-jia Zhao wei guo jian-yu Li Shu-sen Wu State Key Lab of Materials Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China

As a ceramic material,AlN has very good thermophysical and mechanical *** addition,AlN is an effective refining agent for Mg alloys because it has a lattice constant similar to that of ***,AlN is an ideal reinforcement for magnesium matrix composites(MMCs),and is attracting increasing *** review addresses the development of preparation technologies for AlN-reinforced Mg matrix *** mainstream preparation techniques include stir casting,melt infiltration,powder metallurgy,and in-situ *** addition,the advantages and disadvantages of these techniques are analyzed in depth,and it is pointed out that the next direction for the preparation of high-performance AlN-reinforced MMCs is less aluminization and multiple technologies integration.

关键词： AlN MMCs preparation thermophysical property mechanical property

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Investigation of the role of aziridine bonding agents on the aging of the composite solid rocket propellant(CSRP)

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航空动力学报 2008年第11期23卷 2101-2106页

作者： Amged A Ali ZHANG jian-wei CAI guo-biao School of Astronautics Beijing University of Aeronautics and Astronautics Beijing 100191 China

The role of bonding agents on the aging characteristics is one of the important research *** program of the prepared propellant samples was conducting as follows:Five samples,two free of bonding agents,and three containing an aziridine based bonding agents(MAPO,HX-752,MAT4),four samples based on different bonding and curing agents all were aged at 70 ℃.The prepared bonding agent "MAT4" gave remarkable improvements and resulted in highly stable mechanical properties comparing with HX-752 or *** selected bonding agents family inhibited the rate of decomposition of the propellants during the aging periods and supported the propellant matrix against decomposition at the elevated temperatures.

关键词：氮丙啶黏结剂老化现象复合固体火箭推进剂航空动力系统

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Hydrazone derivatives in agrochemical discovery and development

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Chinese Chemical Letters 2024年第3期35卷 104-113页

作者： Ya Wang Shengxin guo Lijiao Yu wei Zhang Zhenchao Wang Yonggui Robin Chi jian Wu National Key Laboratory of Green Pesticide Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationGuizhou UniversityHuaxi DistrictGuiyang 550025China Division of Chemistry&Biological Chemistry School of Physical&Mathematical SciencesNanyang Technological UniversitySingapore 637371Singapore

As a common active substructure,hydrazone has attracted increasing attention and is considered essential for pesticide *** has been widely regarded as a potential insecticidal,antibacterial,antifungal,antiviral,and herbicidal *** this review,we highlight the pesticide versatility of hydrazone fragments and provide a comprehensive summary of the biological activity,structure-activity relationship analysis(SARs),and primary mechanism of their *** profile is expected to give valuable information for discovering new pesticides.

关键词： Hydrazone Agrochemicals Biological activity Structure-activity relationship Preliminary mechanism

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