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缂丝“四季西湖”团扇的设计与实践

艺术与设计（理论版） 2017年第4期 135-137页

作者：孙逸梅张建涛李建亮浙江理工大学服装学院杭州310018

文章从杭州旅游文化纪念品的角度出发,选取了著名的西湖十景中代表性的四季风景,运用缂丝的工艺技法制作成精致典雅的团扇,其中以桥为贯穿元素并搭配四季代表性花卉,既演绎了杭州西湖秀美的四季风光,也展现了中国丝绸高超的织造技艺,并... 详细信息

文章从杭州旅游文化纪念品的角度出发,选取了著名的西湖十景中代表性的四季风景,运用缂丝的工艺技法制作成精致典雅的团扇,其中以桥为贯穿元素并搭配四季代表性花卉,既演绎了杭州西湖秀美的四季风光,也展现了中国丝绸高超的织造技艺,并从中引申出对中国缂丝技艺传承与创新的思考。

关键词：缂丝西湖团扇设计

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

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Science China life Sciences 2025年第1期68卷 300-302页

作者： Ze-Min lin Mai Xiang Wen-Hui Wei Shu-Hui Fan li Chen Jie Wang Xiao-Qian Yang Chun-Hao Yang Shi-Jun He jian-Ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

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水下自密实混凝土封底在苏通大桥的应用

施工技术 2005年第S1期34卷 256-258页

作者：宋伟明陶建飞李青中港集团第二航务工程局湖北武汉430000

介绍了水下自密实混凝土的配合比设计,生产,检验方法及验收等一系列问题,总结了苏通大桥承台成功封底的施工工艺,对以后同类施工有一定指导和借鉴。

关键词：水下自密实混凝土水下封底应用

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超声波细胞粉碎法提取东北红松松针总黄酮

中国食品添加剂 2018年第4期29卷 118-127页

作者：刘宁王冉李健刘涛黎晨晨哈尔滨商业大学食品工程学院哈尔滨150076

目的:优化松针总黄酮提取工艺,为合理利用东北松针资源提供理论依据。方法:以黑龙江省小兴安岭红松松针为原料,在单因素实验基础上,结合Box-Benhnken中心组合原理及响应面优化实验条件。结果:最优提取工艺参数:料液比为1∶65 g/mL,超声... 详细信息

目的:优化松针总黄酮提取工艺,为合理利用东北松针资源提供理论依据。方法:以黑龙江省小兴安岭红松松针为原料,在单因素实验基础上,结合Box-Benhnken中心组合原理及响应面优化实验条件。结果:最优提取工艺参数:料液比为1∶65 g/mL,超声波功率比为70%,超声总时间为46 min,乙醇体积分数为55%,工作与间歇时间比为3/2(s/s)。该条件下松针总黄酮得率约为4.88%,为超声波细胞粉碎法提取松针黄酮的最佳工艺条件。结论:超声波细胞粉碎法更省时,可显著提高松针总黄酮得率,该方法为东北红松松针黄酮的提取提供了理论依据。

关键词：细胞破碎提取工艺总黄酮

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试论文化产品的创作动机及其引导策略

韶关学院学报 2016年第7期37卷 22-26页

作者：邓丽琼刘建滔李阳飞广东医学院学报编辑部广东湛江524023

从哲学社会科学、新闻舆论、文艺作品和网络文化四个层面,揭示文化产品创作主体从事创作活动的内部动机(认知需求、创新期望、自由意志、价值认可)和外部动机(政策法规、监控惩处、荣誉赞扬、资金奖励)。在构建文化产品创作动机理论模... 详细信息

从哲学社会科学、新闻舆论、文艺作品和网络文化四个层面,揭示文化产品创作主体从事创作活动的内部动机(认知需求、创新期望、自由意志、价值认可)和外部动机(政策法规、监控惩处、荣誉赞扬、资金奖励)。在构建文化产品创作动机理论模型的基础上,阐述相应的引导策略,包括完善知识产权保护体系、加大原创资金支持力度、提升文化评奖影响力和加强对外文化传播交流。

关键词：文化产品动机引导策略市场经济

Sulfolane‑Based Flame‑Retardant Electrolyte for High‑Voltage Sodium‑Ion Batteries

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Nano-Micro Letters 2025年第2期17卷 498-516页

作者： Xuanlong He Jie Peng Qingyun lin Meng li Weibin Chen Pei liu tao Huang Zhencheng Huang Yuying liu Jiaojiao Deng Shenghua Ye Xuming Yang Xiangzhong Ren Xiaoping Ouyang jianhong liu Biwei Xiao jiangtao Hu Qianling Zhang Graphene Composite Research Center College of Chemistry and Environmental EngineeringShenzhen UniversityShenzhen 518060People’s Republic of China Center of Electron Microscopy State Key Laboratory of Silicon and Advanced Semiconductor MaterialsSchool of Materials Science and EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China GRINM(Guangdong)Research Institute for Advanced Materials and Technology FoshanGuangdong 528051People’s Republic of China College of Energy Engineering Zhejiang UniversityHangzhouZhejiang 310027People’s Republic of China School of Materials Science and Engineering Xiangtan UniversityXiangtan 411105People’s Republic of China Shenzhen Eigen-Equation Graphene Technology Co.Ltd Shenzhen 518000People’s Republic of China

Sodium-ion batteries hold great promise as next-generation energy storage ***,the high instability of the electrode/electrolyte interphase during cycling has seriously hindered the development of *** particular,an unstable cathode–electrolyte interphase(CEI)leads to successive electrolyte side reactions,transition metal leaching and rapid capacity decay,which tends to be exacerbated under high-voltage ***,constructing dense and stable CEIs are crucial for high-performance *** work reports localized high-concentration electrolyte by incorporating a highly oxidation-resistant sulfolane solvent with non-solvent diluent 1H,1H,5H-octafluoropentyl-1,1,2,2-tetrafluoroethyl ether,which exhibited excellent oxidative stability and was able to form thin,dense and homogeneous *** excellent CEI enabled the O3-type layered oxide cathode NaNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2)(NaNMF)to achieve stable cycling,with a capacity retention of 79.48%after 300 cycles at 1 C and 81.15%after 400 cycles at 2 C with a high charging voltage of 4.2 *** addition,its nonflammable nature enhances the safety of *** work provides a viable pathway for the application of sulfolane-based electrolytes on SIBs and the design of next-generation high-voltage electrolytes.

关键词： Sodium-ion batteries Sulfolane-based electrolyte High voltage Layered oxide cathode Flame retardant

FSD1 inhibits glioblastoma diffuse infiltration through restriction of HDAC6-mediated microtubule deacetylation

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Science China life Sciences 2025年

作者： Dake Xiao Haowen Ran lishu Chen Yuanyuan li Yan Cai Songyang Zhang Qinghui Qi Huiran Wu Cheng Zhang Shuailiang Cao Lanjuan Mi Haohao Huang Ji Qi Qiuying Han Haiqing Tu Huiyan li tao Zhou Fangye li Ailing li jianghong Man Nanhu Laboratory National Center of Biomedical Analysis School of Traditional Chinese Medicine Capital Medical University Department of Neurosurgery General Hospital of Central Theater Command of Chinese PLA School of life and Health Sciences Huzhou College Department of Neurosurgery Beijing Fengtai Hospital Department of Neurosurgery First Medical Center of PLA General Hospital

The infiltration of glioblastoma multiforme(GBM) is predominantly characterized by diffuse spread, contributing significantly to therapy resistance and recurrence of GBM. In this study, we reveal that microtubule deacetylation, mediated through the downregulation of fibronectin type III and SPRY domain-containing 1(FSD1), plays a pivotal role in promoting GBM diffuse infiltration. FSD1 directly interacts with histone deacetylase 6(HDAC6) at its second catalytic domain, thereby impeding its deacetylase activity on α-tubulin and preventing microtubule deacetylation and depolymerization. This inhibitory interaction is disrupted upon phosphorylation of FSD1 at its Ser317 and Ser324 residues by activated CDK5, leading to FSD1 dissociation from microtubules and facilitating HDAC6-mediated α-tubulin deacetylation. Furthermore, increased expression of FSD1 or interference with FSD1 phosphorylation reduces microtubule deacetylation, suppresses invasion of GBM stem cells, and ultimately mitigates tumor infiltration in orthotopic GBM xenografts. Importantly, GBM tissues exhibit diminished levels of FSD1 expression, correlating with microtubule deacetylation and unfavorable clinical outcomes in GBM patients. These findings elucidate the mechanistic involvement of microtubule deacetylation in driving GBM cell invasion and offer potential avenues for managing GBM infiltration.

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基于消费者介入理论的在线购买行为影响要素及预测研究

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管理工程学报 2025年第2期39卷 144-161页

作者：陶婉琼王子卓王健浙江工商大学统计数据工程技术与应用协同创新中心浙江杭州310018 浙江大学管理学院浙江杭州310030 浙江吉利控股集团有限公司浙江杭州310051 浙江工商大学管理工程与电子商务学院杭州310018 浙江工商大学现代商贸研究中心杭州310018

本文主要研究消费者在线购买行为的影响。本文首先从参与强度、消费者类型、购物流程类型和广告点击次数四个维度定义了表征消费者在线购买决策心理特征的消费者介入水平,然后基于消费者介入理论分别从群体水平和个体水平的视角分析消... 详细信息

本文主要研究消费者在线购买行为的影响。本文首先从参与强度、消费者类型、购物流程类型和广告点击次数四个维度定义了表征消费者在线购买决策心理特征的消费者介入水平,然后基于消费者介入理论分别从群体水平和个体水平的视角分析消费者介入水平维度对其购物数量和购物时间间隔等行为的影响。以此为基础,本文采用多种机器学习方法构建了消费者在线购买行为预测模型。通过对不同预测模型的比较发现,神经网络回归模型对购物数量预测的误差性最小和拟合度最高,而梯度提升回归模型对购物时间间隔预测的性能最好。同时,通过特征变量的重组设置对比实验,本文验证了在购买行为预测模型中引入介入水平维度的有效性和合理性。研究结果揭示了消费者介入水平对在线购买行为的影响规律,不仅丰富了相关理论,而且对网购平台和商家精确预测消费者购买行为、优化服务策略等方面具有重要的指导意义。

关键词：决策科学电子商务消费者介入在线购买行为预测模型

Degradation of organics using LaFeO_(3)as a persulfate activator under low-intensity ultra-violet-light irradiation:Catalytic performance and mechanism

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Journal of Rare Earths 2022年第7期40卷 1043-1052页

作者： Yumei li jian Fan Xiaonan Feng tao tao School of Environment Huazhong University of Science and TechnologyWuhan 430074China School of Energy and Environment Inner Mongolia University of Science and TechnologyBaotou 014010China

ABO_(3)-type perovskite oxides with abounding defect structures and diverse physical chemistry attributes have been extensively studied in heterogeneous *** LaFeO_(3)perovskites fabricated via the sol-gel method were used as peroxydisulfate(PDS)activators for methylene blue(MB)degradation under low-intensity ultra-violet(UV)-light to evaluate the degradation efficiency of organic pollutants and *** results indicate that under low-intensity UV irradiation,the developed UV/LaFeO_(3)/PDS system shows excellent degradation ability of organic pollutants in a wide pH *** spin resonance and radical quenching experiments verify that SO_(4)^(·-),·OH,h^(+)and ^(1)O_(2)are generated during the activation process,and ^(1)O_(2)plays a dominant role in MB *** of low oxidation state Fe(Ⅱ)and O_(2)^(2-)/O^(-)on the LaFeO_(3)surface shows that oxygen vacancy,as the electron transfer mediator,enhances the redox cycle efficiency of Fe(Ⅱ)/Fe(Ⅲ).Photogenerated electrons of LaFeO_(3)involved in the cyclic transformation of Fe(Ⅱ)/Fe(Ⅲ)and PDS activation further increase the number of active radicals and thus promote the synergistic effect of photocatalytic coupled with sulfate radicalbased advanced oxidation processes.

关键词： LaFeO_(3) Peroxydisulfate Singlet oxygen Low-intensity UV-light Rare earths