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Some Analyses on Effects of Site Classification on Ground Motion Characteristics in the Chi-Chi,Taiwan Earthquake

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Earthquake Research in China 2006年第4期20卷 435-448页

作者： Dong Di Yang jian liu rui Institute of Engineering Seismology of Qingdao City Qingdao 266003 China

According to the epicenter distance and the site classification, the 404 groups of earthquake recordings of the main shock of the Chi-Chi, Taiwan China earthquake in 1999 are catalogued. Based on these data, we analyze the statistical features of duration, PGA, envelopes and the response spectra ratio of the horizontal and vertical components of the acceleration recordings. The results of these analyses show that the effect of site classification on the acceleration of various components is obvious; furthermore, fault direction also has certain effects on the characteristics of the horizontal components of ground motion. The detailed research results are as follows：（ 1 ） the duration of the horizontal components of acceleration records increases with the softening of the site; （2） the direction of fault slip has some effects on PGA＇s attenuation features; （3） the average envelopes of acceleration records at different distances and site dames are basically single peak functions of time and the envelopes of horizontal and vertical components of ground motion are obviously different; （4） with the same epicenter distance, EW/NS response spectrum ratios tend to approximate 1.0 as the site becomes softer and the period shorter. V/H response spectrum ratios in short periods （〈 0. 1s） increase with the softening of site, however, V/H ratios within the long-period range （〉 characteristic period） decrease with the softening of the site, and the decrease of V/EW ratio speeds up relatively.

关键词： Site Duration Envelope Response spectrum ratio

Formation Process and Properties of Phytic Acid Conversion Coatings on Magnesium

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Journal of Surface Engineered Materials and Advanced Technology 2011年第1期1卷 15-21页

作者： jian-rui liu Yi-Na Guo Wei-Dong Huang 不详

A chromium-free conversion coating treatment for magnesium by phytic acid solution was studied. The formation process of phytic acid conversion coating was studied through measuring the open circuit potential (OCP) and weight change of the pure magnesium in the different conversion treatment time. The morphologies and compositions of the coatings were determined by SEM and EDS respectively. The conversion coating has the multideck structure with netlike morphology which is similar to the chromate conversion coating, and is mainly composed of Mg, P, O and C. The contents of C and P and the size of the cracks in different layers decrease from the external layer to the inner layer. The hydroxyl groups and phosphate carboxyl groups in the coating which have the similar properties to organic paintcoat are beneficial to the combination of substrate and organic paintcoat. The formation mechanism and thickness variation of the conversion coatings are also discussed.

关键词： Magnesium Chemical Conversion Coatings Phytic Acid Formation Mechanism

Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

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World Journal of Clinical Oncology 2025年第1期16卷 43-52页

作者： Zhi-jian Tang Yuan-Ming Pan Wei Li rui-Qiong Ma jian-liu Wang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Cancer Research Center Beijing Chest HospitalBeijing 101149China Department of Thoracic Surgery Sichuan Provincial People's HospitalChengdu 610072Sichuan ProvinceChina

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment *** To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural *** Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression *** genes were sourced from the MitoCarta3.0 *** discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation *** the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were *** In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy *** average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation *** average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation *** The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

关键词： Ovarian cancer Mitochondria Prognosis Immunotherapy Neural network

Effect of Two Kinds of Different Combined Oral Contraceptives Used on Bone Mineral Density in Women of Reproductive Age

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Journal of Reproduction and Contraception 2011年第3期22卷 145-151页

作者： rui-jian liu Ling GAI Yi-fang JIA Ping GAI Xiao-jie YU Provincial Hospital affiliated to Shandong University Jinan 250014 China Key Laboratory for Improving Birth Outcome Technique Shandong Provincial Institute of Science and Technology for Family Planning Jinan 250002 China

Objective To compare bone mineral density （BMD） among users of ethinylestradiol/ desogestrel, ethinylestradiol/cyproterone acetate and nonhormonal control subjects. Methods The study included 154 women aged 25-40 years. Forty-six women were using ethinylestradiol/desogestrel （group A） and 55 women using ethinylestradiol/cyproterone acetate （group B）for 24 months and 53 women using nonhormonal contraception as control subjects （group C）. BMD of the lumbar spine and femoral neck were obtained using dual energy X-ray absorptiometry, comparing mean BMD changes in combined oral contraceptives （COCs） users with nonusers. Results For 24 months of treatment, lumbar spine and femoral neck BMD values in women who used ethinylestradiol/desogestrel and ethinylestradiol/cyproterone acetate were not significantly different compared with the baseline and the values of subjects in nonuser （P〉0.05）. Conclusion There was no statistical difference in BMD between the users of ethinylestradiol/desogestrel or ethinylestradiol/cyproterone acetate and nonusers.

关键词： combined oral contraceptives (COC) ethinylestradiol/desogestrel ethinylestradiol/ cyproterone acetate bone mineral density (BMD)

Observation of topological charge transformations in acoustic vortex using passive periodic systems

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 140-147页

作者： Di-Chao Chen Xie liu Changqing Xu Da-jian Wu Ying Cheng Xiao-Jun liu School of Physics and Technology Nanjing Normal University Key Laboratory of Modern Acoustics School of Physics Nanjing University

Vortex transmutation utilizes a periodic system, which not only enables the alteration of the topological charge(TC) of unstable input vortices but also facilitates their transformation into stable structures. This approach is crucial for investigating the characteristics of vortices in various wave systems. Here, we achieve acoustic vortex TC transmutation by employing a welldesigned dual-structured plate external system(DPES). The interactions between the acoustic vortex and the finite-order discrete rotational symmetry lead to the transformation of its topological charge when complete rotational symmetry is broken to Nthorder discrete symmetry. Our results experimentally demonstrate the acoustic vortex TC transmutation based on passive artificial structures, enabling numerous applications in particle manipulation and information multiplexing as well as advancing our understanding and control over free-space acoustic vortices.

关键词： acoustic vortex topological charge transformation artificial structure

Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders:drug stability,targeting efficiency,and safety

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Neural Regeneration Research 2025年第7期20卷 1883-1899页

作者： Mingyu Zhang Chunyu Xiang Renrui Niu Xiaodong He Wenqi Luo Wanguo liu rui Gu Department of Orthopedic Surgery China-Japan Union Hospital of Jilin UniversityChangchunJilin ProvinceChina

Various nanoparticle-based drug delivery systems for the treatment of neurological disorders have been widely ***,their inability to cross the blood–brain barrier hampers the clinical translation of these therapeutic *** are nanoparticles composed of lipid bilayers,which can effectively encapsulate drugs and improve drug delivery across the blood–brain barrier and into brain tissue through their targeting and ***,they can potentially treat traumatic and nontraumatic central nervous system *** this review,we outlined the common properties and preparation methods of liposomes,including thin-film hydration,reverse-phase evaporation,solvent injection techniques,detergent removal methods,and microfluidics ***,we comprehensively discussed the current applications of liposomes in central nervous system diseases,such as Alzheimer's disease,Parkinson's disease,Huntington's disease,amyotrophic lateral sclerosis,traumatic brain injury,spinal cord injury,and brain *** studies related to liposomes are still in the laboratory stage and have not yet entered clinical ***,their application as drug delivery systems in clinical practice faces challenges such as drug stability,targeting efficiency,and ***,we proposed development strategies related to liposomes to further promote their development in neurological disease research.

关键词： Alzheimer's disease amyotrophic lateral sclerosis brain tumors central nervous system Huntington's disease liposome drug delivery neurological disorders Parkinson's disease spinal cord injury traumatic brain injury

Multi-receptive field interaction network for shape from polarization

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Science China(Information Sciences) 2025年第1期 394-395页

作者： Yini PENG rui liu Zhiyuan ZHANG Zhongyuan WANG Jiayi MA Xin TIAN Electronic Information School Wuhan University Computer Science School Wuhan University Wuhan Institute of Quantum Technology

Shape from polarization (SfP) method can use the polarization information in reflected light to estimate the surface normal of the target,which can further reconstruct the shape of the *** a simple image capture process,it can use low-cost equipment to meet a high precision imaging requirement,which can be used in remote scenes and other applications.

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论七、九、十部乐与隋唐政治、音乐之关系

吕梁学院学报 2016年第4期6卷 1-10页

作者：李建栋刘睿安徽师范大学中国诗学中心安徽芜湖241002

七、九、十部乐与隋唐政治关系密切。就各部乐的演奏次序而言,隋唐两朝前期七、九、十部乐多按"清乐型部乐→胡乐型部乐"的次序演奏,重在突出政治上的华夷之别。两朝后期则多按"胡乐型部乐→清乐型部乐"的次序演奏,其政治功能明显让位... 详细信息

七、九、十部乐与隋唐政治关系密切。就各部乐的演奏次序而言,隋唐两朝前期七、九、十部乐多按"清乐型部乐→胡乐型部乐"的次序演奏,重在突出政治上的华夷之别。两朝后期则多按"胡乐型部乐→清乐型部乐"的次序演奏,其政治功能明显让位于娱乐功能;就演奏频次而言,在隋唐国力上升时期,七、九、十部乐演奏频繁,反之,演奏频次明显减少,诸部乐演奏频次可视为考虑国家强弱的风向标。七、九、十部乐又属于隋唐音乐体系中重要的一支。就发展历程而言,七、九、十部乐的发展历程与唐大曲的发展历程关系密切。隋唐七、九、十部乐多经历了"套曲→大曲"的发展历程,这也是唐大曲形成的一种模式;就曲式结构而言,七、九、十部乐以"歌、舞曲→解曲"的曲式结构为主,这无疑是唐大曲"散拍器乐曲或歌舞曲→缓拍器乐曲或歌舞曲→促拍器乐曲或歌舞曲"曲式结构的一个重要渊源。

关键词：部乐政治音乐大曲

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang Xin liu jian Zhang Ya Gao Shuyue Li Cui Chang Xiang liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein