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Multifactor analysis of patients with oral sensory complaints in a case-control study

Chinese Medical Journal 2020年第23期133卷 2822-2828页

作者： jian-qiu jin Hong-Mei Cui Ying Han Sha Su Hong-Wei Liu Department of Oral Medicine Peking University School and Hospital of StomatologyBeijing 100081China Department of Stomatology Beijing HospitalNational Center of GerontologyBeijing 100730China Department of Stomatology Suzhou Vocational Health CollegeSuzhouJangsu 215009China Department of Stomatology Beijing Friendship HospitalCapital Medical UniversityBeijing 100069China

Background:There are an increasing number of patients with oral sensory complaints(OSCs)presenting to our dental *** most dentists,it is difficult to distinguish burning mouth syndrome(BMS)from other oral mucosal diseases that may cause symptoms such as burning *** is beneficial to effectively distinguish OSC patients to reduce misdiagnosis and eliminate burning symptoms as much as ***:Patients with oral burning sensations in the oral mucosal disease clinic were collected from the Peking University Hospital of Stomatology between September 1,2014 and December 31,*** excluding oral candidiasis,anemic stomatitis,dental material allergy,and other diseases from patients with oral sensory complaints,basic conditions such as gender,age,education level,job status,hyperglycemia,hypertension,hyperlipidemia,history of brain abnormalities,history of cervical spondylitis,history of thyroid disease,history of thyroid disease and insomnia were *** BMS patients were compared with the control *** t test and Chi-square test were used for statistical analysis to compare the clinical symptoms of these diseases and explore the risk factors for ***:In this case-control study,395 patients(321 females and 74 males,mean age 55.26±10.51 years)with oral sensory complaints and 391 healthy controls(281 females and 110 males,mean age 47.11±13.10 years)were enrolled,among which,8.4%(33/395)had oral candidiasis,1.3%(5/395)had dental material allergy,0.8%(3/395)had anemic stomatitis and 0.5%(2/395)had lichen planus.A total of 352 patients were eventually diagnosed with *** and depression were more severe in BMS patients,as were the incidences of sleep disorders and brain *** regression analysis showed that age(odds ratio[OR]=2.79,95%confidence interval[CI]:1.61-4.83,P<0.001),total cholesterol level(OR=2.92,95%CI:1.32-6.50,P=0.009)and anxiety score(OR=1.75,95%CI:1.01-2.77,P=0.017)significantly increased the incidence

关键词： Oral sensory complaints Burning mouth syndrome Patch test Candida Anemia Anxiety Depression

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Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

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Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： Xiaoqin Li jian Xiang Lu qiu Xiaohan Chen Yinkun Zhao Yujue Wang Qu Yue Taotao Gao Wenlong Liu Dan Xiao Zhaoyu jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

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Knowledge Management and Innovation

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厦门大学学报（自然科学版） 2002年第S1期41卷 240-页

作者： qiu Yuan-fu, GU Xin-jian, qiu jin-dong (Institute of Production Engineering, Zhejiang University, Hangzhou 31 0027, China)

The 21 st century is an era of knowledge, know le dge is said to be particularly important. Knowledge and information have become the economy’s primary raw material and its most important outcome. Under increas ingly competitive pressure, many enterprises are examining how they can better m anage their knowledge. During the last years, another concept has gained increas ing interest: knowledge management. The emerging field of knowledge management a ddresses the broad processes of locating, organizing, transferring and more effi ciently using knowledge and expertise within an enterprise. An enterprise’s and its employees’ knowledge is regarded as the most important corporate capital in the arising global information society. Knowledge management therefore aims towa rds improving an enterprise’s ability to acquire, develop, preserve, distribute and use knowledge. This paper describes a conceptual model of knowledge manageme nt and innovation, focusing on analyzing the knowledge management and innovation process, trying to make knowledge more productive and create knowledge more eff iciently. In this paper, an integral and conceptual model of knowledge management and inno vation is presented first; then, the knowledge work process is analyzed, which i s conceptualized as a knowledge spiral; subsequently, knowledge management proce ss is conceptualized into knowledge development, knowledge acquisition, knowledg e transfer, knowledge sharing, knowledge utilization and knowledge evaluatio n, all of which can be conceptualized as a knowledge cycle; furthermore, the fac ilitating conditions for implementing knowledge management are analyzed; in the end, the input-output model of knowledge innovation is given as well as the mai n tools for assisting knowledge management are summarized.

关键词： knowledge management knowledge innovation

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复杂软土地区深基坑内支撑与锚索共同作用初探

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岩土工程学报 2014年第S2期36卷 396-399页

作者：周赞良付艳斌丘建金赵军贺闯深圳市勘察测绘院有限公司广东深圳518028 深圳大学土木工程学院广东深圳518060 深圳市鹏瑞地产开发有限公司广东深圳518054

针对填海软土地区深基坑采用的排桩加上部内支撑、下部预应力锚索复合支护结构进行了分析,基坑上部刚度较大的内支撑的存在有效减小了基坑的变形、优化了围护结构的受力,下部预应力锚索可以为桩基提供施工所需空间、减小支撑与地下室施... 详细信息

针对填海软土地区深基坑采用的排桩加上部内支撑、下部预应力锚索复合支护结构进行了分析,基坑上部刚度较大的内支撑的存在有效减小了基坑的变形、优化了围护结构的受力,下部预应力锚索可以为桩基提供施工所需空间、减小支撑与地下室施工的相互影响。通过现场监测情况分析及数值模拟初步探索了内支撑与锚索的共同作用,体现了上撑下锚复合支护结构在软土地区的施工便利性及造价优越性,可为类似工程提供参考。

关键词：软土深基坑内支撑锚索共同作用

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AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis

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Neural Regeneration Research 2025年第8期20卷 2408-2419页

作者： Ruiqi qiu Mingzhu Yang Xiuxiu jin jingyang Liu Weiping Wang Xiaoli Zhang jinfeng Han Bo Lei Henan Eye Hospital Henan Provincial People’s HospitalPeople’s Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Eye Institute Henan Academy of Innovations in Medical ScienceZhengzhouHenan ProvinceChina Branch of National Clinical Research Center for Ocular Disease Henan Provincial People’s HospitalZhengzhouHenan ProvinceChina Academy of Medical Science Zhengzhou UniversityZhengzhouHenan ProvinceChina

Retinitis pigmentosa is a group of inherited diseases that lead to retinal degeneration and photoreceptor cell ***,there is no effective treatment for retinitis pigmentosa caused by PDE6B ***-associated virus(AAV)-mediated gene therapy is a promising strategy for treating retinitis *** aim of this study was to explore the molecular mechanisms by which AAV2-PDE6B rescues retinal *** do this,we injected retinal degeneration 10(rd10)mice subretinally with AAV2-PDE6B and assessed the therapeutic effects on retinal function and structure using dark-and light-adapted electroretinogram,optical coherence tomography,and ***-independent acquisition-mass spectrometry-based proteomic analysis was conducted to investigate protein expression levels and pathway enrichment,and the results from this analysis were verified by real-time polymerase chain reaction and western ***2-PDE6B injection significantly upregulated PDE6βexpression,preserved electroretinogram responses,and preserved outer nuclear layer thickness in rd10 *** expressed proteins between wild-type and rd10 mice were closely related to visual perception,and treating rd10 mice with AAV2-PDE6B restored differentially expressed protein expression to levels similar to those seen in wild-type *** Encyclopedia of Genes and Genome analysis showed that the differentially expressed proteins whose expression was most significantly altered by AAV2-PDE6B injection were enriched in phototransduction ***,the phototransductionrelated proteins Pde6α,Rom1,Rho,Aldh1a1,and Rbp1 exhibited opposite expression patterns in rd10 mice with or without AAV2-PDE6B ***,Bax/Bcl-2,p-ERK/ERK,and p-c-Fos/c-Fos expression levels decreased in rd10 mice following AAV2-PDE6B *** data suggest that AAV2-PDE6B-mediated gene therapy promotes phototransduction and inhibits apoptosis by inhibiting the ERK signaling pathway and upr

关键词： apoptosis AAV2-PDE6B ERK1/2 gene therapy phototransduction proteomics rd10 retinitis pigmentosa

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深圳地区软弱地基处理若干问题分析

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土工基础 2004年第5期18卷 26-29,43页

作者：丘建金深圳市勘察测绘院广东深圳518028

对近年来深圳地区软弱地基处理中若干热点问题进行论述,并结合工程实例就有关设计和施工中存在的问题进行分析说明。

关键词：软弱地基加固方法滨海软土排水固结法强夯块石墩法

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搅拌水泥土抗压强度特性试验

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土工基础 2010年第4期24卷 91-94页

作者：骆以道丘建金郭敏燕深圳市勘察测绘院广东深圳518028 武汉大学土木与建筑学院武汉430072

对深圳市某滨海软土区淤泥进行了不同水泥掺入比的搅拌水泥土抗压强度室内试验,试验结果可为类似滨海相淤泥搅拌水泥土抗压强度特性研究积累一些经验数据,也可为搅拌水泥土强度试验方法提供参考。

关键词：水泥土搅拌法滨海软土抗压强度地基处理室内试验

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多种支护结构在深大基坑工程中的应用

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广州建筑 2009年第4期37卷 35-39页

作者：田玉山周赞良丘建金深圳市勘察测绘院有限公司深圳518028

针对深圳市怡景中心城基坑工程(基坑深约22.0m)的地质情况、周围环境条件,采用了咬合桩与锚索、复合土钉墙及桩锚支护等多种围护方案,通过现场监测结果表明,地铁联络线隧道轨面沉降观测点变形在1.0～-6.82mm之间,各点变形基本稳定,满足... 详细信息

针对深圳市怡景中心城基坑工程(基坑深约22.0m)的地质情况、周围环境条件,采用了咬合桩与锚索、复合土钉墙及桩锚支护等多种围护方案,通过现场监测结果表明,地铁联络线隧道轨面沉降观测点变形在1.0～-6.82mm之间,各点变形基本稳定,满足隧道轨面变形不超过7.0mm的要求;地铁联络线顶地面沉降观测点沉降量基本稳定,累计沉降量在2.18～4.46mm之间,咬合桩等多种支护结构能较好地适应该地层深基坑工程,是一种在类似工程中值得推广的围护结构。

关键词：深基坑咬合桩复合土钉墙桩锚

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支撑监视喉镜下声带息肉摘除术和电子喉镜治疗声带息肉的效果对比

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中国当代医药 2017年第21期24卷 44-46页

作者：苏志坚陈秋桓金焕庭叶继才邱海东广东省肇庆市高要区人民医院耳鼻喉科广东肇庆526114

目的探讨支撑监视喉镜下声带息肉摘除术和电子喉镜治疗声带息肉的临床效果。方法回顾性分析2015年1月~2016年12月在我院接受治疗的120例声带息肉患者的临床资料,按照手术方式分为对照组和研究组,各60例。对照组采用电子喉镜下声带息肉... 详细信息

目的探讨支撑监视喉镜下声带息肉摘除术和电子喉镜治疗声带息肉的临床效果。方法回顾性分析2015年1月~2016年12月在我院接受治疗的120例声带息肉患者的临床资料,按照手术方式分为对照组和研究组,各60例。对照组采用电子喉镜下声带息肉摘除术,研究组给予支撑监视喉镜下声带息肉摘除术。比较两组的临床疗效及并发症发生情况。结果研究组的临床治疗效果显著优于对照组,差异有统计学意义(P0.05)。结论支撑监视喉镜下声带息肉摘除术治疗声带息肉的效果确切,值得临床推广应用。

关键词：带蒂声带息肉广基声带息肉支撑监视喉镜电子喉镜

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Spatiotemporal evolution of ecosystem service value and topographic gradient effect in the Da-Xiao Liangshan Mountains in Sichuan Province,China

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Journal of Mountain Science 2023年第8期20卷 2344-2357页

作者： jin Tao CHEN Yang SHU Bo GAO Min qiu jian School of Architecture Southwest Jiaotong UniversityChengdu 611756China Leshan Municipal Bureau of Planning and Natural Resources Leshan 614000China School of Architecture and Civil Engineering Xihua UniversityChengdu 610039China

The Da-Xiao Liangshan mountains are critical ecological function areas and essential ecological barriers in the upper reaches of the Yangtze River in *** study selected a total of six periods of land use land cover(LULC)data from 1995 to 2020,to estimate the ecosystem service value(ESV)and analyzed its spatiotemporal evolution and topographic gradient *** results showed that:(1)The ESV increased by 1.1 billion yuan,with an increase rate of 1.47%from 1995 to *** time periods,2005–2010 and 2015–2020,showed more significant increases than other periods.(2)The elevation and slope of mountainous areas determine the type of land use and further influence the spatial pattern of ESV.(3)Although woodland and grassland are the main land use types of the study area(more than 90%),the hydrological regulation function of the water area partially compensated for the impact of the encroachment of the built-up area on the ESV of grassland.(4)The spatial distribution of ESVs showed an inverted V-shaped characteristic as the topographic gradient increased,with the dominant position being the 5th topographic gradient ***,this study provided relevant recommendations for ecosystem protection and *** findings of this study clarified the influence of topographical factors on the spatial differentiation of ESV and provided novel insights into ecosystem protection.

关键词： Ecosystem service value(ESV) Dynamic evolution Terrain gradient effect Spatial pattern Liangshan Yi region

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