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Microfluidic technology for multiphase emulsions morphology adjustment and functional materials preparation

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Chinese Journal of Chemical Engineering 2016年第6期24卷 677-692页

作者： XuehuiGe Hong Zhao Tao Wang jian chen jianhong Xu Guangsheng Luo The State Key Lab of Chemical Engineering Department of Chemical Engineering Tsinghua University Beijing 100084 China

Multiphase emulsions could be used as templates in considerable fields such as coating, optical materials, stan- dard particles and biomedicine. Among various emulsion forming methods, microfluidic technology, with good monodispersity, high controllability and operation simplicity, has been widely used in the preparation of multi- phase emulsions with different systems. This review would focus on the basic principles of forming multiphase emulsions, the recent progress in controlling multiphase flow in microfluidics, and preparation of functional ma- terials with microfluidics mainly by the authors＇ research group. We believe that the review will contribute to the readers in this prospective area very well. ~ 2016 The Chemical Industry and Engineering Society of China, and Chemical Industry Press. All rights reserved.

关键词： Multiphase emulsionsMicrofluidicsFlow controlFunctional microspheres

Experimental study on the multiscale scattering of high-velocity heterogeneous bodies

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Applied Geophysics 2022年第1期19卷 1-10,143页

作者： qin Zhen-Chao Wei jian-Xin Di Bang-Rang Wang Di State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing 102249China CNPC Key Laboratory of Geophysical Exploration China University of Petroleum(Beijing)Beijing 102249China.

There are complex heterogeneous entities in the underground medium,and the heterogeneous scale has a substantial impact on wave *** this study,we used a set of 11 samples of glass beads as high-velocity heterogeneous bodies to evaluate the impact of such heterogeneous bodies on the propagation of *** vary the heterogeneous scale by changing the diameter of the glass beads from 0.18 to 11 mm while keeping the same volume proportion(10%)of the beads for the set of 11 *** pulse transmission method was used to record measurements at the ultrasonic frequencies of 0.34,0.61,and 0.84 MHz in the homogeneous *** relationship between P-wave fi eld features and heterogeneity scale,P-wave velocity,and the multiple of the wave number and heterogeneous scale(ka)was observed in the laboratory,which has sparked widespread interest and *** scale affects P-wave propagation,and its wave field changes are *** waveform,amplitude,and velocity of the recorded P-waves correlate with the heterogeneous *** the forward scattering while large-scale heterogeneities,noticeable direct and diff racted waves are observed in the laboratory,which indicates that the infl uence of direct and diff racted waves cannot be ignored for large-scale *** relationship between velocity and ka shows frequency dependence;the reason is that the magnitude of change in velocity caused by wave number is diff erent from that caused by heterogeneous *** to the change in the recorded waveform,amplitude variation,or the relationship between the velocity measured at diff erent frequencies and the heterogeneous scale,the identifi ed turning points of the ray approximation are all around ka=*** ka is less than 1,the velocity changes slowly and gradually approaches the eff ective medium *** ray velocity measured for heterogeneous media with large velocity perturbations in the laboratory is signifi cantly smaller than the

关键词： heterogeneous bodies multiscale scattering velocity dispersion pulse transmission method

A Shrinkage Estimator for Combination of Bioassays

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Acta Mathematicae Applicatae Sinica 2007年第3期23卷 467-476页

作者： jian Xiong D.G. chen Zhen-hai Yang College of Applied Sciences Beijing University of Technology Beijing 100022 China School of Mathematics and Information Science Guangzhou University Guangzhou 510006 China Department of Mathematics and Statistics South Dakota State University Brookings SD 57007 USA

A shrinkage estimator and a maximum likelihood estimator are proposed in this paper for combination of bioassays. The shrinkage estimator is obtained in closed form which incorporates prior information just on the common log relative potency after the homogeneity test for combination of bioassays is accepted. It is a practical improvement over other estimators which require iterative procedure to obtain the estimator for the relative potency. A real data is also used to show the superiorities for the newly-proposed procedures.

关键词： Common log relative potency parallel-line bioassay slope-ratio bioassay prior information,posterior distribution marginal sufficiency

Ni–P coating on AZ31 magnesium alloy and its crystallization

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Rare Metals 2013年第5期32卷 465-468页

作者： Chun-Mei Wang jian-qing Wang Bing Zhang Run-Bing Niu Jin-Ku Yu qin Jing State Key Laboratory of Metastable Materials Science and Technology Yanshan University North China Institute of Aerospace Engineering

Amorphous Ni-P coating was plated on AZ31 magnesium alloy via the electroless plating technique, and the plated alloy was subsequently annealed. X-ray dif- fraction （XRD）, scanning electron microscopy （SEM）, energy dispersive spectroscopy （EDS）, and differential scanning calorimetry （DSC） were used to characterize the coating. The results show that the hardness of the coating is much higher than that of bare magnesium alloy, which further increases after crystallization. The electrochemical polarization and salt spray tests show that the coating exhibits a much higher corrosion resistance than that of the bare magnesium alloy. Moreover, the crystallized coating still exhibits a much stronger corrosion resistance than that of the bare magnesium alloy, although its corrosion resistance is lower than that of the as-plated one.

关键词： Ni-P coating Magnesium alloy Crystallization Corrosion resistance

2015-2021年重庆市肺结核患者发现延误及影响因素分析

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中国防痨杂志 2024年第2期46卷 183-189页

作者：陈健石林雷蓉蓉余雅汪清雅吴成果刘小秋中国疾病预防控制中心中国现场流行病学培训项目北京100050 重庆市结核病防治所防治科重庆400050 中国疾病预防控制中心结核病预防控制中心北京102206

目的:分析2015-2021年重庆市肺结核患者发现延误情况及影响因素,为减少患者发现延误提供科学依据。方法:从“中国疾病预防控制信息系统”子系统“传染病报告信息管理系统”收集2015-2021年重庆市肺结核患者相关信息,包括报告时间、患者... 详细信息

目的:分析2015-2021年重庆市肺结核患者发现延误情况及影响因素,为减少患者发现延误提供科学依据。方法:从“中国疾病预防控制信息系统”子系统“传染病报告信息管理系统”收集2015-2021年重庆市肺结核患者相关信息,包括报告时间、患者的人口学特征(性别、年龄、职业)、地区、患者来源、疾病诊断、发病日期和诊断日期,共获得174 067例患者信息。2015-2021年肺结核患者发现延误率的变化采用Joinpoint回归模型进行趋势分析,采用多因素logistic回归分析发现延误的影响因素。结果:2015-2021年重庆市肺结核患者发现延误时间中位数为31(10,73) d,年均发现延误率为53.25%(92 695/174 067);由2015年的58.20%(15 093/25 935),下降至2021年的50.18%(11 026/21 974)。2015-2021年发现延误率总体呈下降趋势(AAPC=-2.5%,t=-2.095,P=0.036),2015-2019年发现延误率下降趋势差异有统计学意义(APC=-4.1%,t=-4.313,P=0.049),2019-2021年发现延误率变化差异无统计学意义(APC=0.8%,t=0.248,P=0.827)。多因素logistic回归分析显示,女性(OR=1.036,95%CI:1.015~1.059)、45~64岁年龄组(OR=1.095,95%CI:1.065~1.125)、无业(离退)人群(OR=1.233,95%CI:1.177~1.294)、农(牧、渔)民(工)(OR=1.624,95%CI:1.546~1.710)、学龄前儿童(OR=3.581,95%CI:2.271~5.761)、工人(OR=1.134,95%CI:1.062~1.213)、渝东北地区(OR=1.270,95%CI:1.244~1.312)、重庆市外(OR=1.136,95%CI:1.087~1.187)、病原学阳性(OR=1.033,95%CI:1.013~1.055)是肺结核患者出现发现延误的危险因素。结论:重庆市肺结核患者的发现延误现象较为严重,随时间变化总体呈下降趋势。需要重点关注重点地区和重点人群发现延误情况,并采取综合性措施。

关键词：结核肺因素分析重庆市

Fracture Network Volume Fracturing Technology in High-temperature Hard Formation of Hot Dry Rock

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Acta Geologica Sinica(English Edition) 2021年第6期95卷 1828-1834页

作者： chen Zuo XU Guoqing ZHOU jian LIU jiankun SINOPEC Research Institute of Petroleum Engineering Beijing 102206China

It is more difficult for a hot dry rock to form a fracture network system than shale due to its special lithology, physical and mechanical properties under high temperature. The essential characteristics, rock mechanics and in-situ stress characteristics of a hot rock mass have been systematically studied by means of laboratory tests and true tri-axial physical simulation. The fracture initiation and propagation characteristics under different geological and engineering conditions are physically simulated, and the main controlling factors for the formation of a complex fracture network are revealed. The technology of low displacement for enhancing thermal cracking, gel fluid for expanding fracture and variable displacement cyclic injection for increasing a fracture network has been applied in the field, and good results have been achieved. Microseismic monitoring results demonstrate that complex fractures were formed in the field test, and the stimulation volume for heat exchanging reaches more than 3 million cubic meters. The research results play an important role in the stimulation technology of an enhanced geothermal system(EGS) and realize a breakthrough for power generation.

关键词： hot dry rock granite fracture network natural fractures thermal cracking cyclic injection volume stimulation Gonghe Basin

Generalized Competition Index of Primitive Digraphs

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Acta Mathematicae Applicatae Sinica 2017年第2期33卷 475-484页

作者： Li-hua YOU Fang chen jian SHEN Bo ZHOU School of Mathematical Sciences South China Normal University Department of Mathematics Texas State University

For any positive integers k and m, the k-step m-competition graph C^（D） of a digraph D has the same set of vertices as D and there is an edge between vertices x and y if and only if there are distinct m vertices vi, v2, .., Vm in D such that there are directed walks of length k from x to vi and from y to vi for all 1 ≤ i≤ m. The m-competition index of a primitive digraph D is the smallest positive integer k such that Ckm（D） is a complete graph. In this paper, we obtained some sharp upper bounds for the m-competition indices of various classes of primitive digraphs.

关键词： competition index m-competition index scrambling index primitive digraph

Diagnostic strategies for diseases with fever in dental clinics

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2023年第4期24卷 352-358页

作者： jian YUAN Chuanxia LIU Zaiye LI Qianming chen Stomatology Hospital School of StomatologyZhejiang University School of MedicineClinical Research Center for Oral Diseases of Zhejiang ProvinceKey Laboratory of Oral Biomedical Research of Zhejiang ProvinceCancer Center of Zhejiang UniversityHangzhou 310006China Department of Oral Medicine West China Hospital of StomatologySichuan UniversityState Key Laboratory of Oral DiseasesNational Clinical Research Center for Oral DiseasesChengdu 610041China

Fever is an increase in body temperature beyond the normal range,acting as a protective inflammatory *** article summarizes diseases with fever encountered in dental clinics,including what is known about pyrexia in coronavirus infection,and further proposes a“six steps in one”identification and analysis strategy to guide the clinical work of *** to the mechanism of occurrence,fever is divided into pyrogenic and nonpyrogenic types.

关键词： fever mechanism diseases

汉语母语孤独症谱系障碍“日历计算专家”认知加工特征与脑机制分析

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康复学报 2024年第2期34卷 161-166页

作者：陈健徐曙天邬钰玮陈松美单春雷上海市徐汇区田林街道社区卫生服务中心上海200233 上海中医药大学康复医学院上海201203 上海中医药大学附属岳阳中西医结合医院上海200437 上海市第三康复医院上海200436 上海交通大学医学院康复研究院上海200025 上海交通大学医学院附属同仁医院上海200336

目的分析汉语母语孤独症谱系障碍(ASD)“日历计算专家”(SCC)认知加工特征,并结合头颅磁共振成像(MRI)分析相关脑机制。方法对1例具有SCC特征的汉语母语ASD患者进行随机正常日历计算测试、调整新日历强记能力测试、数字计算能力测试... 详细信息

目的分析汉语母语孤独症谱系障碍(ASD)“日历计算专家”(SCC)认知加工特征,并结合头颅磁共振成像(MRI)分析相关脑机制。方法对1例具有SCC特征的汉语母语ASD患者进行随机正常日历计算测试、调整新日历强记能力测试、数字计算能力测试、线方向判断(JLO)测试、失用症检查(口面失用、言语失用和意念运动性失用检查)、额叶功能(FAB)测试和蒙特利尔认知功能评估(MoCA)。采用MRI头颅检查SCC患者,并与健康受试者比较,探讨其脑器质性损伤情况。结果 (1)日历计算能力测试:SCC患者“随机正常日历计算”正确率为80%,平均每题答题时间11.8 s,而健康受试者“随机正常日历计算”平均正确率仅为16%。(2)日历强记能力测试:SCC患者“调整新日历计算”正确率仅为20%。(3)数字计算能力:SCC患者加法和除法计算正确率均为100%,平均耗时分别为10.67 s和58.19 s;减法和乘法计算正确率均为93.8%,平均耗时分别23.51 s和34.88 s。(4) JLO测试:SCC患者JLO测试得分为27分。(5)失用症检查:部分口面失用,言语失用检查基本正常,但存在意念运动性失用(得分32分)。(6) FAB和MoCA评分:SCC患者FAB评分13分,主要表现为相似性测验和言语流畅度等方面功能受损。MoCA评分17分,主要表现为认知功能障碍,抽象、语言功能缺失明显。(7) MRI检查:与健康受试者比较,SCC患者左侧颞叶前方蛛网膜囊肿,两侧海马体积小,以左侧更为明显,左侧顶枕叶皮质萎缩伴皮质下白质胶质增生。结论该汉语母语孤独症谱系障碍存在“日历计算专家”能力,除视空间能力较好外,额叶功能、左顶叶功能(数字计算能力降低、意念运动性失用)均受损;“日历计算专家”能力可能与左侧颞叶蛛网膜囊肿后右侧顶叶的功能性代偿有关。

关键词：孤独症谱系障碍学者综合征日历计算专家认知功能脑机制

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