检索结果-南通市图书馆

Bond length and interface failure mechanism of anchor cable under continuous radial pressure conditions

在线全文

学校读者我要写书评

暂无评论

International Journal of Mining Science and Technology 2025年第2期35卷 231-247页

作者： jian Ouyang Xiuzhi Shi Xianyang qiu Zongguo Zhang Zeyu Li School of Resources and Safety Engineering Central South UniversityChangsha 410083China

The anchoring capacity of the anchor cable is closely related to the bonding length and radial pressure *** field pull-out tests,theoretical analysis,numerical simulation,and industrial tests,this study clarifies the relationship between radial pressure and bonding length for the ultimate pullout force and reveals the microscopic failure process of the resin-rock interface in the anchoring *** results show that the ultimate load increases with the increase of bonding length in three different stages:rapid,slow,and uniform *** new mechanical model developed considering radial pressure describes the inverse relationship between radial pressure and the plastic zone on the bonding section,and quantifies the reinforcing effect of confining pressure on the anchoring *** the pull-out process of the anchor cable,the generation of failure cracks is in the order of orifice,bottom,and middle of the *** pressure can effectively enhance the ultimate pull-out force,alleviate the oscillation increase of pull-out force,and inhibit resin cracking,but will produce an external crushing *** also reveals the synergistic effect between bonding length and radial pressure,and successfully carries out industrial tests of anchor cable support,which ensures the stability of the stope roof and provides an important reference for the design of anchor cable support in deep high-stress mines.

关键词： Radial pressure Anchor cable Bond length Numerical simulation Interface failure Microscopic process

Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Life Sciences) 2025年第1期68卷 103-115页

作者： Xizi Luo nan Zhang Yuntao Liu Beibei Du Xuan Wang Tianxu Zhao Bingqiang Liu Shishun Zhao Jiazhang qiu Guoqing Wang State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Basic MedicineJilin UniversityChangchun 130012China College of Mathematics Jilin UniversityChangchun 130021China Department of Cardiology China-Japan Union HospitalJilin UniversityChangchun 130033China Bioinformatic Lab School of MathematicsShandong UniversityJinan 250100China State Key Laboratory for Diagnosis andTreatmentof Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministryof EducationCollegeof Veterinary MedicineJilin UniversityChangchun 130062China

The coronavirus disease 2019(COVID-19)outbreak caused by the severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)developed into a global health *** microthrombus caused by SARS-CoV-2 infection is a common complication in patients with *** microthrombosis as a complication of SARS-CoV-2 infection is the primary cause of cardiac injury and death in patietns with severe *** this study,we performed single-cell sequencing analysis of the right ventricular free wall tissue from healthy donors,patients who died during the hypercoagulable period of characteristic coagulation abnormality(CAC),and patients who died during the fibrinolytic period of *** collected 61,187 cells enriched in 24 immune cell subsets and 13 cardiac-resident cell *** found that in the course of SARS-CoV-2 infected heart microthrombus,MYO1 Ehigh RASGEF1 Bhighmonocyte-derived macrophages promoted hyperactivation of the immune system and initiated the extrinsic coagulation pathway by activating chemokines CCL3,*** series of events is the main cause of cardiac microthrombi following SARS-CoV-2 *** a SARS-CoV-2 infected heart microthrombus,excessive immune activation is accompanied by an increase in cellular iron content,which in turn promotes oxidative stress and intensifies intercellular *** induces cells to alter their metabolic environment,resulting in increased sugar uptake via the glycosaminoglycan synthesis *** addition,high levels of reactive oxygen species generated by elevated iron levels promote increased endogenous malondialdehyde synthesis in a subpopulation of cardiac endothelial *** exacerbates endothelial cell dysfunction and exacerbates the coagulopathy process.

关键词： SARS-CoV-2 cardiac microthrombosis immune hyperactivation cell competition

Adaptive Early Warning Method of Cascading Failures Caused by Coordinated Cyber-Attacks

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2025年第1期11卷 406-423页

作者： Yufei Wang June Li jian qiu Yangrong Chen Key Laboratory of Aerospace Information Security and Trusted Computing Ministry of EducationSchool of Cyber Science and EngineeringWuhan UniversityWuhan Hubei430072China China Electric Power Research Institute Beijing102209China Electric Power Planning&Engineering Institute Beijing 100120China

In order to accurately receive early warning of the cascading failures caused by coordinated cyber-attacks(CFCC)in grid cyber-physical systems(GCPS),an adaptive early warning method of CFCC is ***,the evolutionary mechanism of CFCC is analyzed from the attackers'view,the CFCC mathematical model is established,and the transition processes of GCPS running states under the influence of CFCC staged failures are ***,the mathematical model of the adaptive early warning method is ***,the mathematical model of the adaptive early warning method is mapped as an adaptive control process with tolerating staged failures damage,and the solving process is presented to infer the CFCC and its next evolution trend.A decision-making idea for the optimal active defense scheme is proposed considering the costs and gains of various defense ***,to verify the effectiveness of the adaptive early warning method,the warning and defense processes of a typical CFCC are simulated in a GCPS experimental system based on CEPRI-36 BUS.

关键词： Adaptive control theory cascading failures coordinated cyber-attacks early warning grid cyber-physical systems.

A novel method for simultaneous measurement of^(222)Rn and^(220)Rn progeny concentrations measured by an alpha spectrometer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2025年第1期36卷 127-139页

作者： Zhong-Kai Fan Jia-Le Sun Hao-Xuan Li Xiang-Ming Cai Hui Yang Shou-Kang qiu Yan-Liang Tan jian Shan School of Nuclear Science and Technology University of South ChinaHengyang 421001China College of Physics and Electronic Engineering Hengyang Normal UniversityHengyang 421008China

The accumulation of^(222)Rn and^(220)Rn progeny in poorly ventilated environments poses the risk of natural radiation exposure to the public.A previous study indicated that satisfactory results in determining the^(222)Rn and^(220)Rn progeny concentrations by measuring the total alpha counts at five time intervals within 560 min should be expected only in the case of high progeny concentrations in *** complete the measurement within a relatively short period and adapt it for simultaneous measurements at comparatively lower^(222)Rn and^(220)Rn progeny concentrations,a novel mathematical model was proposed based on the radioactive decay *** model employs a nonlinear fitting method to distinguish nuclides with overlapping spectra by utilizing the alpha particle counts of non-overlapping spectra within consecutive measurement cycles to obtain the concentrations of^(222)Rn and^(220)Rn progeny in *** verification experiments were conducted using an alpha *** experimental results demonstrate that the concentrations of^(222)Rn and^(220)Rn progeny calculated by the new method align more closely with the actual circumstances than those calculated by the total count method,and their relative uncertainties are all within±16%.Furthermore,the measurement time was reduced to 90 min,representing an acceleration of 84%.The improved capability of the new method in distinguishing alpha particles with similar energies emitted from ^(218)Po and^(212)Bi,both approximately 6 MeV,contributed to realizing more accurate *** proposed method has the potential advantage of measuring relatively low concentrations of^(222)Rn and^(220)Rn progeny in air more quickly via air filtration.

关键词： ^(222)Rn ^(220)Rn Progeny concentration Nonlinear fitting method Alpha spectrometer

Modified Pulsatilla decoction alleviates 5-fluorouracil-induced intestinal mucositis by modulating the TLR4/MyD88/NF-κB pathway and gut microbiota

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第7期31卷 110-129页

作者： Yi-Tong qiu Xin-Yi Luo Ya-Feng Deng Xue Zheng jian-Guo qiu Lin-Sheng Zhang Xiao-Qi Huang Xue-Bao Zheng Hai-Yang Huang School of Pharmaceutical Sciences Guangzhou University of Chinese MedicineGuangzhou 525000Guangdong ProvinceChina Druggability Research Team Dongguan Institute of Guangzhou University of Chinese MedicineDongguan 523808Guangdong ProvinceChina Institute of Traditional Chinese Medicine Dongguan Hospital of Traditional Chinese MedicineDongguan 523000Guangdong ProvinceChina

BACKGROUND Modified Pulsatilla decoction(PD),a PD with licorice and ejiao,is a classic Traditional Chinese Medicine formula with significant efficacy in treating intestinal mucositis(IM)induced by tumor ***,its specific molecular and biological mechanisms remain *** To investigate the therapeutic effect and mechanism of modified PD in *** This study used an IM mouse model established using 5-fluorouracil injections to investigate the effects of the modified PD(3,6,and 12 g/kg)in *** primary chemical components of the modified PD were identified using liquid chromatography-mass *** weight loss,diarrhea scores,intestinal length,histopathological scores,and inflammatory cytokine levels were measured to evaluate the effects of the modified PD in *** on the TLR4/MyD88/NF-κB pathway were evaluated using western blot *** intestinal microbiota was characterized using Illumina NovaSeq *** The results showed that modified PD significantly improved weight loss and diarrhea and shortened the intestines in IM ***,modified PD suppressed the TLR4/MyD88/NF-κB pathway and downregulated the expression of reactive oxygen species,lipopolysaccharides,and pro-inflammatory cytokines(IL-1β,TNF-α,IFN-γ,IL-6,IL-8,and IL-17),while increasing the expression of the anti-inflammatory cytokine ***,modified PD protected the intestinal mucosal barrier by increasing the expression of tight junction proteins(occludin-1,claudin-1,and ZO-1)and ***,16S rDNA sequencing revealed that modified PD improved intestinal *** Our research offers new insights into the potential mechanism of modified PD in alleviating IM and provides experimental evidence supporting its pharmaceutical application in clinical IM treatment.

关键词： Modified Pulsatilla decoction Intestinal mucositis Oxidative stress Gut microbiota,TLR4/MyD88/NF-κB pathway Inflammatory response

Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： Xiaoqin Li jian Xiang Lu qiu Xiaohan Chen Yinkun Zhao Yujue Wang Qu Yue Taotao Gao Wenlong Liu Dan Xiao Zhaoyu Jin Panpan Li Institute for Advanced Study Chengdu UniversityChengdu 610106SichuanChina School of Mechanical Engineering Chengdu UniversityChengdu 610106SichuanChina College of Food and Biological Engineering Chengdu UniversityChengdu 610106SichuanChina Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 611731SichuanChina College of Materials Science and Engineering Sichuan UniversityChengdu 610065SichuanChina

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries(AZIBs). These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose(Xylo) molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn^(2+)ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Aqueous Zn-ion battery Electrolyte additive Solvation structure Electrode/electrolyte interface Zn anode

Mixture of Bacillus Amyloliquefaciens and Bacillus Pumilus Modulates Community Structures of Rice Rhizosphere Soil to Suppress Rice Seedling Blight

在线全文

学校读者我要写书评

暂无评论

Rice science 2025年第1期32卷 118-130,I0067-I0070页

作者： jianG nan qiu Jiehua TIAN Dagang SHI Huanbin LIU Zhiquan WEN Hui XIE Shuwei CHEN Huizhe WU Meng KOU Yanjun State Key Laboratory of Rice Biology and Breeding China National Rice Research InstituteHangzhou 311400China Biotechnology Research Institute Fujian Academy of Agricultural SciencesFuzhou 350003China State Key Laboratory of Soil and Sustainable Agriculture the Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China

Rice seedling blight,caused by various fungi,including Fusarium oxysporum,poses a severe threat to rice *** awareness grows regarding the environmental and safety hazards associated with the application of fungicides for managing rice seedling blight,there has been a shift in focus towards biological control *** this study,we isolated biocontrol bacteria from paddy fields that significantly inhibited the growth of *** in vitro and identified the strains as Bacillus amyloliquefaciens T40 and Bacillus pumilus ***,our findings indicated that the combined application of these Bacillus strains in soil was more effective in reducing the incidence of rice seedling blight than their individual *** of 16S and internal transcribed spacer rRNA gene sequencing data revealed that the mixture of the T40 and T208 strains exhibited the lowest average clustering coefficients,which were negatively correlated with the biomass of ***-inoculated rice ***,this mixture led to higher stochastic assembly(average|βNTI|<2)and reduced selection pressures on rice rhizosphere bacteria compared with individual strain *** mixture of the T40 and T208 strains also significantly increased the expression of defense-related *** conclusion,the mixture of the T40 and T208 strains effectively modulates microbial community structures,enhances microbial network stability,and boosts the resistance against rice seedling *** study supports the development and utilization of biological resources for crop protection.

关键词： application strategy disease control disease resistance microbial community structure microbial community assembly process Oryza sativa

The circadian clock affects starvation resistance through the pentose phosphate pathway in silkworm,Bombyx mori

在线全文

学校读者我要写书评

暂无评论

Insect Science 2025年第1期32卷 55-68页

作者： Tai-Ming Dai jian-Feng qiu Cheng Luo Wen-Zhao Cui Kai Liu jiang-Lan Li Ruji Peng Yang-Hu Sima Shi-Qing Xu School of Life Sciences Suzhou Medical College of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Agricultural Biotechnology&Ecology(IABE) Soochow UniversitySuzhouJiangsu ProvinceChina

Disruption of the circadian clock can affect starvation resistance,but the molecular mechanism is still ***,we found that starvation resistance was significantly reduced in the core gene BmPer deficient mutant silkworms(Per−/−),but the mutant's starvation resistance increased with larval *** natural physiological conditions,the weight of mutant 5th instar larvae was significantly increased compared to wild type,and the accumulation ability of triglycerides and glycogen in the fat bodies was ***,under starvation conditions,the weight consumption of mutant larvae was increased and cholesterol utilization was *** analysis showed that beta-oxidation was significantly upregulated under starvation conditions,fatty acid synthesis was inhibited,and the expression levels of genes related to mitochondrial function were significantly *** investigations revealed that the redox balance,which is closely related to mitochondrial metabolism,was altered in the fat bodies,the antioxidant level was increased,and the pentose phosphate pathway,the source of reducing power in cells,was *** findings suggest that one of the reasons for the increased energy burden observed in mutants is the need to maintain a more robust redox balance in metabolic *** necessitates the diversion of more glucose into the pentose phosphate pathway to ensure an adequate supply of reducing power.

关键词： Bombyx mori circadian clock oxidative stress pentose phosphate pathway starvationresistance

Methods and mechanisms for enhancing the water retention properties of Jiuzhaigou disintegrated rubble soils

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mountain Science 2025年第2期22卷 729-746页

作者： WEI Zeming XI Hongchao PEI Xiangjun ZHANG Xiaochao qiu Mao HUANG Tiao WANG Zhaocheng jianG Junlian DU Jie jian Daijun State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of TechnologyChengdu 610059China Tianfu Yongxing Laboratory Research Center for Carbon Sequestration and Ecological Restoration Chengdu 610213China Jiuzhaigou Administration Aba 623400China

Rubble deposits with a high concentration of rock debris were created after the powerful earthquakes in *** of the restricted soil resources,water leaks,and nutrient deficits,these deposits pose serious obstacles for vegetation *** purpose of this study was to investigate the main mechanisms controlling soil water retention and evaluate the effects of different amendments on the hydraulic characteristics and water-holding capacity of collapsed rubble *** soil,forest humus,crushed straw,and organic components that retain water were added to the altered soils to study the pore structure images and soil-water characteristic *** understory humus to other supplements,the results showed a considerable increase in the soil's saturated and wilting water *** saturated water content and wilting water content rose by 17.9%and 4.3%,respectively,when the percentage of understory soil reached 30%.Additionally,the enhanced soil's microporosity and total pore volume increased by 45.33%and 11.27%,respectively,according to nuclear magnetic *** was shown that while clay particles and organic matter improved the soil's ability to adsorb water,they also increased the soil's total capacity to store *** particulate matter did this by decreasing macropores and increasing capillary *** results offer an essential starting point for creating strategies for soil repair that would encourage the restoration of plants on slopes that have been damaged.

关键词： Pile-ups Amendments Crumbling rubble soils Water holding capacity Soil-water characteristic curves