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Chinese Physics Letters 2022年第5期39卷 58-62页

作者： jian-keng yuan Shuai A.Chen Peng Ye School of Physics State Key Laboratory of Optoelectronic Materials and Technologiesand Guangdong Provincial Key Laboratory of Magnetoelectric Physics and DevicesSun Yat-sen UniversityGuangzhou 510275China Department of Physics The Hong Kong University of Science and TechnologyHong KongChina

Fractonic superfluids are exotic states of matter with spontaneously broken higher-rank U(1)*** broken symmetry is associated with conserved quantities,including not only particle number(i.e.,charge)but also higher moments,such as dipoles,quadrupoles,and angular *** to the presence of such conserved quantities,the mobility of particles is restricted either completely or ***,we systematically study the hydrodynamical properties of fractonic superfluids,especially focusing on the fractonic superfluids with conserved angular *** constituent bosons are called"lineons"with d components in d-dimensional *** the Euler-Lagrange equation,we derive the continuity equation and Navier-Stokes-like equations,in which the angular moment conservation introduces extra ***,we discuss the current configurations related to the *** the conventional superfluid,we study the critical values of velocity fields and density currents,which gives rise to a Landau-like ***,several future directions are discussed.

关键词： Navier Landau angular

Resistance of Cement-based Grouting Materials with Nano- SiO_(2) Emulsion to Chloride Ion Penetration

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 114-119页

作者： LI Shuiping CHENG jian WEI Chao yuan Bin YU Chengxiao College of Architectural Science and Engineering Yangzhou UniversityYangzhou 225127China

The chloride penetration resistance of cement-based grout materials was improved by nano-silica *** of mixtures containing different nano-silica particles or emulsions were exposed in sodium chloride solutions of specific concentrations with different test *** properties of the mixes were assessed in terms of weight loss and compressive strength.X-ray diffraction(XRD)and scanning electron microscopy(SEM)of mixes were performed to analysis the phase evolution and *** results demonstrated that the introduction of nano-SiO_(2) emulsion significantly decreased the compressive strength loss and calcium hydroxide(CH)crystal content of hydration production,and then enhanced the resistance of cement-based grouting materials to chloride ion *** improvement derives from the filling and pozzolanic effects of nano-SiO_(2) particles,which were incorporated via an emulsion and attributed to a well dispersion in grouting matrix.

关键词： grouting materials nano-SiO_(2)emulsion chloride ion penetration,weight loss strength loss

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： yuan Zhao Yidan Zhang Xin Liu jian Zhang Ya Gao Shuyue Li Cui Chang Xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

Unlocking the future:Mitochondrial genes and neural networks in predicting ovarian cancer prognosis and immunotherapy response

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World Journal of Clinical Oncology 2025年第1期16卷 43-52页

作者： Zhi-jian Tang yuan-Ming Pan Wei Li Rui-Qiong Ma jian-Liu Wang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Cancer Research Center Beijing Chest HospitalBeijing 101149China Department of Thoracic Surgery Sichuan Provincial People's HospitalChengdu 610072Sichuan ProvinceChina

BACKGROUND Mitochondrial genes are involved in tumor metabolism in ovarian cancer(OC)and affect immune cell infiltration and treatment *** To predict prognosis and immunotherapy response in patients diagnosed with OC using mitochondrial genes and neural *** Prognosis,immunotherapy efficacy,and next-generation sequencing data of patients with OC were downloaded from The Cancer Genome Atlas and Gene Expression *** genes were sourced from the MitoCarta3.0 *** discovery cohort for model construction was created from 70% of the patients,whereas the remaining 30% constituted the validation *** the expression of mitochondrial genes as the predictor variable and based on neural network algorithm,the overall survival time and immunotherapy efficacy(complete or partial response)of patients were *** In total,375 patients with OC were included to construct the prognostic model,and 26 patients were included to construct the immune efficacy *** average area under the receiver operating characteristic curve of the prognostic model was 0.7268[95% confidence interval(CI):0.7258-0.7278]in the discovery cohort and 0.6475(95%CI:0.6466-0.6484)in the validation *** average area under the receiver operating characteristic curve of the immunotherapy efficacy model was 0.9444(95%CI:0.8333-1.0000)in the discovery cohort and 0.9167(95%CI:0.6667-1.0000)in the validation *** The application of mitochondrial genes and neural networks has the potential to predict prognosis and immunotherapy response in patients with OC,providing valuable insights into personalized treatment strategies.

关键词： Ovarian cancer Mitochondria Prognosis Immunotherapy Neural network

Output Consensus of Heterogeneous Linear MASs via Adaptive Event-Triggered Feedback Combination Control

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IEEE/CAA Journal of Automatica Sinica 2025年第1期 285-287页

作者： Shuo yuan Chengpu Yu jian Sun the School of Automation Beijing Institute of Technology the Beijing Institute of Technology Chongqing Innovation Center

Dear Editor,This letter studies output consensus problem of heterogeneous linear multiagent systems over directed graphs. A novel adaptive dynamic event-triggered controller is presented based only on the feedback combination of the agent's own state and neighbors' output,which can achieve exponential output consensus through intermittent communication. The controller is obtained by solving two linear matrix equations, and Zeno behavior is excluded.

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方钢管混凝土柱穿入式组合节点耗能机制

Practical Secret Sharing Scheme Realizing Generalized Adversary Structure

工程力学 2025年第1期42卷 116-128页

作者：徐庆元雷建雄丁发兴周期石张华帅邱远光杨建军中南大学土木工程学院湖南长沙410075 中铁城建集团有限公司湖南长沙410075 中铁城建第一工程有限公司湖南长沙410075

开展了4个翼缘削弱的钢管混凝土柱穿入式组合节点抗震性能与三维实体有限元精细化模型分析。在混凝土三轴塑性损伤和钢材混合强化模型基础上，进一步引入钢材的韧性损伤模型，探讨了钢梁削弱程度对节点抗震性能与破坏形式的影响规律，... 详细信息

开展了4个翼缘削弱的钢管混凝土柱穿入式组合节点抗震性能与三维实体有限元精细化模型分析。在混凝土三轴塑性损伤和钢材混合强化模型基础上，进一步引入钢材的韧性损伤模型，探讨了钢梁削弱程度对节点抗震性能与破坏形式的影响规律，结果显示引入钢材韧性损伤的有限元模型分析结果与试验结果更加吻合，且钢梁削弱程度降低了该节点的刚度、承载力和耗能。随后对不同钢梁尺寸和柱端拉筋强构造下的组合节点进行了承载力、刚度和塑性耗能分配与失效机制的影响规律分析，分析结果表明：穿入式节点分别在梁-柱抗弯承载力比介于1.66~2.11、梁-柱线刚度比介于1.90~1.96、梁-柱截面刚度比介于1.16~1.21时，将由梁耗能向柱耗能转变;柱端拉筋强构造技术后，由于拉筋直接约束混凝土，大幅度提升了柱端抗弯承载力和耗能能力，组合节点在高轴压比时仍维持梁端失效破坏模式;根据《建筑抗震设计规范》，梁-柱抗弯承载力比取值小于1时为强柱弱梁，这对穿入式组合节点强柱弱梁的定义较为保守。

关键词：方钢管混凝土柱钢-混凝土组合梁穿入式组合节点韧性损伤塑性耗能

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Journal of Computer Science & Technology 2004年第4期19卷 564-569页

作者： yuan-BoGuo jian-FengMa TheMinistryofEducationKeyLaboratoryofComputerNetworksandInformationSecurity XidianUniversityXi＇an710071P.R.China School.ofComputingandAutomatization TianjinPolytechnicUniversityTianjin300160P.R.China

Most existing secret sharing schemes are constructed to realize generalaccess structure, which is defined in terms of authorized groups of participants, and is unable tobe applied directly to the design of intrusion tolerant system, which often concerns corruptiblegroups of participants instead of authorized ones. Instead, the generalized adversary structure,which specifies the corruptible subsets of participants, can be determined directly by exploit ofthe system setting and the attributes of all participants. In this paper an efficient secret sharingscheme realizing generalized adversary structure is proposed, and it is proved that the schemesatisfies both properties of the secret sharing scheme, i.e., the reconstruction property and theperfect property. The main features of this scheme are that it performs modular additions andsubtractions only, and each share appears in multiple share sets and is thus replicated. The formeris an advantage in terms of computational complexity, and the latter is an advantage when recoveryof some corrupted participants is necessary. So our scheme can achieve lower computation cost andhigher availability. Some reduction on the scheme is also done finally, based on an equivalencerelation defined over adversary structure. Analysis shows that reduced scheme still preserves theproperties of the original one.

关键词： secret sharing generalized adversary structure write structure equivalenceclass reduction

Effect of trace HA on microstructure, mechanical properties and corrosion behavior of Mg-2Zn-0.5Sr alloy

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Journal of Materials Science & Technology 2018年第2期34卷 299-310页

作者： jian-Xing Li yuan Zhang Jing-yuan Li jian-Xin Xie School of Materials Science and Engineering University of Science and Technology Beijing Institute for Advanced Materials and Technology University of Science and Technology Beijing

Effect of the addition of trace HA particles into Mg-2Zn-0.5Sr on microstructure, mechanical properties, and bio-corrosion behavior was investigated in comparison with pure Mg. Microstructures of the Mg-2Zn-0.5Sr-xHA composites （x= 0, 0.1 and 0.3 wt%） were characterized by optical microscopy （OM）, scanning electron microscopy （SEM） equipped with energy dispersion spectroscopy （EDS） and X-ray diffraction （XRD）. Results of tensile tests at room temperature show that yield strength （YS） of Mg- 2Zn-0.5Sr/HA composites increases significantly, but the ultimate tensile strength （UTS） and elongation decrease with the addition of HA particles from 0 up to 0.3 wt%. Bio-corrosion behavior was investigated by immersion tests and electrochemical tests. Electrochemical tests show that corrosion potential （Ecorr） of Mg-2Zn-0.5Sr/HA composites significantly shifts toward nobler direction from -1724 to -1660 mVscE and the corrosion current density decreases from 479.8 to 280.8 ***^-2 with the addition of HA particles. Immersion tests show that average corrosion rate of ***/HA composites decreases from 11.7 to 9.1 mm/year with the addition of HA particles from 0 wt% up to 0.3 wt%. Both microstructure and mechanical properties can be attributed to grain refinement and mechanical bonding of HA particles with second phases and α-Mg matrix. Bio-corrosion behavior can be attributed to grain refinement and the formation of a stable and dense CaHPO4 protective film due to the adsorption of Ca^2＋ on HA particles. Our analysis shows that the Mg-2Zn-0.5Sr/0.3HA with good strength and corrosion resistance can be a good material candidate for biomedical applications.

关键词： Magnesium alloys Bio-composites Hydroxyapatite Microstructure Mechanical property Bio-corrosion behavior

Twin-solute, twin-dislocation and twin-twin interactions in magnesium

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Journal of Magnesium and Alloys 2023年第10期11卷 3427-3462页

作者： yuan Yue jian Wang jian-Feng Nie Department of Materials Science and Engineering Monash UniversityVictoria 3800Australia Department of Mechanical&Materials Engineering University of Nebraska-LincolnLincolnNE 68583USA

Magnesium alloys have received considerable research interest due to their lightweight,high specific strength and excellent ***,their plastic deformation is more complicated compared to cubic materials,primarily because their low-symmetry hexagonal closepacked(hcp) crystal *** twinning is a crucial plastic deformation mechanism in magnesium,and twins can affect the evolution of microstructure by interacting with other lattice defects,thereby affecting the mechanical *** paper provides a review of the interactions between deformation twins and lattice defects,such as solute atoms,dislocations and twins,in magnesium and its *** review starts with interactions between twin boundaries and substitutional solutes like yttrium,zinc,silver,as well as interstitial solutes like hydrogen and *** is followed by twin-dislocation interactions,which mainly involve those between {10■2} tension or {10■1} compression twins and , or type *** following section examines twin-twin interactions,which occur either among the six variants of the same {10■2} or {10■1} twin,or between different types of *** resulting structures,including twin-twin junctions or boundaries,tension-tension double twin,and compression-tension double twin,are discussed in ***,this review highlights the remaining research issues concerning the interactions between twins and lattice defects in magnesium,and provides suggestions for future work in this area.

关键词： Magnesium alloys Twin-solute interactions Twin-dislocation interactions Twin-twin interactions Microstructure Mechanical properties

Atropoenantioselective synthesis of heterobiaryl N-oxides via dynamic kinetic resolution

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Science China Chemistry 2022年第12期65卷 2512-2516页

作者： Xi yuan jian Wang College of Chemistry and Materials Science Anhui Normal UniversityWuhu241002China School of Pharmaceutical Sciences Tsinghua UniversityBeijing100084China

A highly efficient enantioselective construction of heterobiaryl N-oxides was developed.A series of axially chiral heterobiaryl N-oxides were generated via the cascade reaction of aminobenzamides with heterobiaryl aldehydes in the presence of chiral phosphoric acids.A number of atropisomers were afforded in moderate to good yields with excellent enantioselectivities and *** results demonstrate that the heterobiaryl N-oxides can be utilized as efficient chiral ligands in asymmetric catalysis.

关键词： heterobiaryl N-oxides dynamic kinetic resolution chiral phosphoric acids atroposelectivity organocatalysis