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An accelerated direct demodulation method for image reconstruction using spherical data from the hard X-ray modulation telescope

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Research in Astronomy and Astrophysics 2013年第8期13卷 991-1012页

作者： Zhuo-Xi Huo jian-feng zhou Department of Engineering Physics and Center for Astrophysics Tsinghua University Key Laboratory of Particle & Radiation Imaging (Tsinghua University) Ministry of Education Key Laboratory of High Energy Radiation Imaging Fundamental Science for National Defense

The hard X-ray modulation telescope （HXMT） mission is mainly devoted to performing an all-sky survey at 1- 250 keV with both high sensitivity and high spatial resolution. The observed data reduction as well as the image reconstruction for HXMT can be achieved by using the direct demodulation method （DDM）. However the original DDM is too computationally expensive for multi-dimensional data with high resolution to be employed for HXMT data. We propose an accelerated direct demodulation method especially adapted for data from HXMT. Simulations are also presented to demonstrate this method.

关键词： methods data analysis methods numerical techniques image processing instrumentation high angular resolution

CAR T Cell Therapy for Hematological Malignancies

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Current Medical Science 2019年第6期39卷 874-882页

作者： Xin YANG Gao-xiang WANG jian-feng zhou Department of Hematology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

As a rapidly progressing field in oncology,the adoptive transfer of T cells that have been genetically modified with chimeric antigen receptors(CARs)has shown striking efficacy in the management of hematological malignancies and has been reported in a number of clinical *** note,CAR T cell therapy has shown extraordinary potential,especially in relapsed/refractory ***,there are still challenges regarding the further development of this strategy,spanning from engineering and manufacturing issues,to limited applications,to accompanying *** this review,we will summarize the general knowledge of this novel method,including receptor composition,applications,adverse events and ***,we will propose several comprehensive recommendations.

关键词： immune therapy chimeric antigen receptor T cells hematological malignancies

Solvent-free and catalyst-free method for the synthesis of 2,4,5-triarylimidazoles under microwave irradiation

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Chinese Chemical Letters 2009年第10期20卷 1198-1200页

作者： jian feng zhou Gui Xia Gong Hui Qin Zhu feng Xia Zhu a Department of Chemistry Huaiyin Teachers CollegeJiangsu Key Laboratory for Chemistry of Low-Dimensional Materials Huaian 223300 China School of Chemistry and Chemical Engineering Key Laboratory of Organic Synthesis of Jiangsu Province Suzhou University Suzhou 215123 China

A facile procedure for the synthesis of 2,4,5-lriarylimidazoles is being reported starting from benzil, aromatic aldehyde and ammonium acetate. The reactions were carried out with catalyst-free, solvent-free and under microwave irradiation conditions in high yield （80-99%） with short time （3-5 min） and environmental benign, as well as convenient operation. The structures of the compounds have been confirmed on the basis of their IR, 1H NMR, and/or 13C NMR, MS, and elemental analyzer.

关键词： Triarylimidazole Benzil Catalyst-free Solvent-free Microwave irradiation

Microwave promoted one-pot synthesis of 3-(2′-amino-3′-cyano-4′-arylpyrid-6′-yl)coumarins

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Chinese Chemical Letters 2009年第1期20卷 37-39页

作者： jian feng zhou Gui Xia Gong feng Xia Zhu San Jun Zhi Department of Chemistry Huaiyin Teachers College Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials Huaian 223300 China School of Chemistry and Chemical Engineering Key Laboratory of Organic Synthesis of Jiangsu Province Suzhou University Suzhou 215123 China

A facile procedure for the synthesis of 3-（2′-amino-3′-cyano-4′-arylpyrid-6′-yl） coumarins are being reported starting from 3- acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR, ^1H NMR, and mass spectral data.

关键词： 3-(2′-Amino-3′-cyano-4′arylpyrid-6′-yl) coumarin Aromatic aldehyde 3-Acetylcoumarin Microwave irradiation

Point source detection performance of Hard X-ray Modulation Telescope imaging observation

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Research in Astronomy and Astrophysics 2015年第11期15卷 1905-1916页

作者： Zhuo-Xi Huo Yi-Ming Li Xiao-Bo Li jian-feng zhou Department of Physics Tsinghua University Centre for Astrophysics Tsinghua University Laboratoire de l'Accélérateur Linéaire Institute of High Energy Physics Chinese Academy of Sciences Department of Engineering Physics Tsinghua University

The Hard X-ray Modulation Telescope（HXMT） will perform an all-sky survey in the hard X-ray band as well as deep imaging of a series of small sky *** expect various compact objects to be detected in these imaging observations. Point source detection performance of HXMT imaging observation depends not only on the instrument but also on the data analysis method that is applied since images are reconstructed from HXMT observed data with numerical methods. The denoising technique used plays an important part in the HXMT imaging data analysis pipeline along with demodulation and source detection. In this paper we have implemented several methods for denoising HXMT data and evaluated the point source detection performances in terms of sensitivities and location accuracies. The results show that direct demodulation with 1-fold cross-correlation should be the default reconstruction and regularization method, although both sensitivity and location accuracy could be further improved by selecting and tuning numerical methods in data analysis used for HXMT imaging observations.

关键词： regularization reconstructed selecting demodulation pixel wavelet pipeline neighborhood tuning histogram

Catalyst-free and solvent-free method for the synthesis of quinoxalines under microwave irradiation

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Chinese Chemical Letters 2009年第6期20卷 672-675页

作者： jian feng zhou Gui Xia Gong Kun Bao Shi San Jun Zhi Department of Chemistry Huaiyin Teachers College Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials Huaian 223300 China School of Chemistry and Chemical Engineering Key Laboratory of Organic Synthesis of Jiangsu Province Suzhou University Suzhou 215123 China

A facile procedure for the synthesis, of quinoxalines is being reported starting from benzil and 1,2-diaminobenzene. The reactions were carried out catalyst-free, solvent-free and under microwave irradiation conditions in high yield （84-98%） with short time （3-6 min） and environmental benign, as well as convenient operation. The structures of all the compounds have been confirmed on the basis of their IR, 1H NMR, and/or 13C NMR, mass spectral data.

关键词： Quinoxaline Benzil 1,2-Diaminobenzene Catalyst-free Solvent-free Microwave irradiation

Mosaic Trisomy 21 and Trisomy 14 as Acquired Cytogenetic Abnormalities without GATA1 Mutation in A Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia

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Chinese Journal of Cancer Research 2011年第3期23卷 239-241页

作者： Yi Xiao Jia Wei Jin-huan Xu jian-feng zhou Yi-cheng Zhang Department of Hematology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

One case of acute megakaryoblastic leukemia （AMKL） with trisomy 21,trisomy 14 and unmutated GATA1 gene in a phenotypically normal girl was *** patient experienced transient myelodysplasia before the onset of *** bone marrow blasts manifested typical morphology of megakaryoblast both by the May-Giemsa staining and under the electronic *** cells were positive for CD13,CD33,CD117,CD56,CD38,CD41 and CD61 in flow cytometry *** study showed karyotype of 48,XX,＋14,＋21 in 40% *** mutations of GATA1 gene in Down syndrome or acquired trisomy 21 were not detected in this case.

关键词： Acute megakaryoblastic leukemia Myelodysplasia Cytogenetics GATA1

Multiple Coatings can Improve the Bond Durability of One-step Self-etching Adhesive to Primary Dentin

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Chinese Medical Sciences Journal 2012年第2期27卷 106-111页

作者： Lin Ma jian-feng zhou Quan Jing Ji-zhi Zhao Kuo Wan Department of Stomatology Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Department of Prosthodontics Peking University School&Hospital of StomatologyBeijing 100081China

Objective To investigate whether multiple coatings can improve the bond durability of one-step self-etching adhesive to primary dentin. Methods Twelve caries-free human primary molars were randomly divided into 2 groups. In group 1, each tooth was hemisected into 2 halves. One half was assigned to the control subgroup 1, which was bonded with a commercially available one-step self-etching adhesive according to the manufacturer＇s instruc- tions; the other half was assigned to experimental subgroup 1, in which the adhesive was applied three times before light curing. In group 2, one split half tooth was bonded with a commercially available one-step self-etching adhesive according to the manufacturer＇s instructions; for the other half, three layers of adhesive were applied with each successive layer of light curing. Specimens were stored in 0.9% NaC1 containing 0.02% sodium azide at 37℃ for 18 months and then were subjected to microtensile bond strength test and the fracture mode analysis. Results When the adhesive was applied three times before light curing, the bond strength of the ex- perimental subgroup 1 was significantly higher than that of the control subgroup 1 （47.46__＋13.91 vs. 38.12＋11.21 MPa, P〈O.05）. When using the technique of applying multiple layers of adhesive with each successive layer of light curing, no difference was observed in bond strength between the control subgroup and the experimental subgroup （39.40＋8.87 vs. 40.87-＋9.33 MPa, P〉O.05）. Conclusion Multiple coatings can improve the bond durability of one-step self-etching adhesive to primary dentin when using the technique of light-curing after applying 3 layers of adhesive.

关键词： self-etching adhesive microtensile bond strength test primary dentin multiple coatings

Analysis on Surface Longitudinal Cracking of Q345D Slab

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Journal of Iron and Steel Research International 2014年第S1期21卷 108-112页

作者： Bo ZHANG Zheng-liang XUE Zhi LIAO Shen-de WANG Hua-wei ZHENG jian-feng zhou The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and Technology Technology Center of Liangang Group Lianyuan Iron and Steel Corporation of Hunan Hualing

The surface longitudinal cracking of peritectic steel Q345 D slab was studied by means of metallographic microscopy and scanning electron microscopy. The results show that the surface longitudinal cracking is caused by the shell repeatedly tearing and healing under the action of stress, which is due to disruption of the steel matrix continuity with inclusion aggregation on the shell surface. The relative precautions of reducing the cracking are raised according to the practical situation.

关键词： peritectic steel slab continuous casting surface longitudinal cracking