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Transcervical Approach for Resection of Lateral Skull Base Tumors

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Journal of Otology 2007年第2期2卷 102-108页

作者： LIU jian-feng1, zhang Qiu-hang1, 2, YANG Da-zhang1, QU Qiu-yi2 1 Department of Otorhinolaryngology, China Japan Friendship Hospital, Beijing, China 2 Department of Otorhinolaryngology Head & Neck Surgery, Xuanwu Hospital, Capital University of Medical Science, Beijing, 100053, China Department of Otorhinolaryngology China Japan Friendship Hospital Beijing China Department of Otorhinolaryngology Head & Neck Surgery Xuanwu Hospital Capital University of Medical Science Beijing 100053 China

Objectives Conventional approaches for removal of lateral skull base tumors, including transmandibular, infratemporal fossa, preauricular transzygmatic subtemporal approaches, are major invasive procedures that often sacrifice hearing and cause abnormal occlusion and cosmetic defects. Reports of the transcervical approach for resection of skull base tumors are rare, although it was described for resection of clival chordomas in as early as 1966. The purpose of this study is to review our experiences in management of lateral skull base tumors using the transcervical approach. Study Design Retrospective chart review. Methods Six lateral skull base tumor cases treated with transcervical approach procedures were reviewed, including the medical records. Results There were 4 males and 2 females. Age ranged from 12 through 52 years. Histopathological diagnoses included malignant schwannoma(n = 1), malignant carotid body tumor(n = 1), heamangioma(n=1), schwannoma (n=2) and pleomorphic adenoma (n = 1). Transcervical techniques were used in all cases with the use of microscope in the lateral skull base area. Complete tumor removal was achieved in all cases. Postoperative radiotherapy was implemented in 1 case of malignant schwannoma and 1 case of malignant carotid body tumor. Jugular foramen syndrome occurred as a surgical complication in 1 case of malignant Schwannoma of the vagus nerve. There was no tumor recurrence during the 10 - 42 month follow-up period. Conclusion Compared with conventional approaches, the transcervical approach provides a easy, safe, minimal invasive and effective procedure for removal of selected lateral skull base tumors.

关键词： skull base tumor transcervical approach excision

盾构地中对接冻结加固模型试验(Ⅰ)——冻结过程中地层冻结温度场的分布特征

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岩土力学 2017年第2期38卷 368-376页

作者：石荣剑岳丰田张勇陆路中国矿业大学深部岩土力学与地下工程国家重点实验室江苏徐州221116 中国矿业大学力学与土木工程学院江苏徐州221116

针对软土地层中盾构地中对接冻结加固施工边界条件复杂、形成冻结壁体积小且形状不规则的特点,以上海地区某盾构对接冻结加固工程为原型,按照相似理论设计进行了冻结加固模型试验,分析了冻结过程中地层温度场的分布规律,获得以下结论:... 详细信息

针对软土地层中盾构地中对接冻结加固施工边界条件复杂、形成冻结壁体积小且形状不规则的特点,以上海地区某盾构对接冻结加固工程为原型,按照相似理论设计进行了冻结加固模型试验,分析了冻结过程中地层温度场的分布规律,获得以下结论:在盾构壳体内表面保温的条件下,冻结管内部冻土的平均发展速度是冻结管外部的1.5倍左右;冻结28 h后,冻结管内部冻结壁的温度分布基本稳定,盾构壳体与土体交接面的温度均处于-20℃左右,内部冻结壁的平均温度约为外部的1.9倍。在同圈冻结管的叠加作用下,冻结过程中冻结壁主面和界面的温度变化规律基本一致,仅在冻结初期有少许差别。在外圈冻结管的低温屏蔽作用下,内圈冻结管对外部土体基本不发挥冻结作用,在不同冻结管排间距及多根冻结管交叉冻结的情况下,冻结管外部的冻土扩展规律基本相同,仅两排冻结管之间的土体温度分布存在差别。研究结果表明,盾构地中对接冻结加固形成的冻结壁形状与外圈冻结管的布置形式相似,形成的冻结壁厚度及平均温度在冻结28 h后基本稳定。

关键词：人工冻结冻结壁温度场盾构对接模型试验

High-dense nanocrystalline W-based alloy prepared by hot isostatic pressing with uniform microstructure, ultrahigh hardness and good thermal stability

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Tungsten 2025年第1期7卷 120-136页

作者： Zao-Ming Wu Lin He Lin-Sen Ye Xiao-feng Yang Jia-Jia zhang Hong-Bo Lei Institute of Materials China Academy of Engineering Physics

High-density uniform microstructure nanocrystalline W-10wt.% Cr-5wt.% Y（W-10Cr-5Y） alloy with an average grain size of 85 nm and a relative density of 99.8% was successfully prepared.W-Cr-Y alloys with different amounts of second-phase particles were prepared by high-energy ball milling and hot isostatic pressing *** effects of composition design,ball milling parameters,and sintering parameters on the microstructure of W-Cr-Y alloys were studied.A feasible technology for controlling the synthesis of high-density nanocrystalline W-based alloys has been *** microstructure analysis of nanocrystalline W-10Cr-5Y alloy shows that there are two types of doping in the second phase:intergranular doping and intragranular *** "uniform distribution YOx-rich particles" effectively suppresses the grain growth of W and leads to the formation of nanocrystalline W-10Cr-5Y alloy.W-10Cr-5Y has an ultra-high hardness,with a Vickers hardness of 1312±12 kgf·***-temperature annealing treatment shows that W-10Cr-5Y has good thermal stability at 1000 and1100℃,as demonstrated by the comparison of Vickers hardness and grain size between annealed and unannealed alloys.

关键词： Hot isostatic pressing Microstructure Nanocrystalline tungsten Thermal stability Vickers hardness

氟化氢铵洗孔工艺及其在谢米兹拜伊铀矿床的应用

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中国矿业 2016年第10期25卷 128-132,136页

作者：李建东张峰原渊中广核铀业发展有限公司北京100029 核工业北京化工冶金研究院北京101149

钻孔清洗不仅是钻孔成孔过程的重要工艺,也是地浸矿山生产阶段最为繁重的工作。在研究谢米兹拜伊铀矿床地质与水文地质条件的基础上,本文主要介绍了该矿床的一种洗孔工艺-氟化氢铵洗孔工艺。其基本原理是将氟化氢铵与硫酸注入到钻孔内,... 详细信息

钻孔清洗不仅是钻孔成孔过程的重要工艺,也是地浸矿山生产阶段最为繁重的工作。在研究谢米兹拜伊铀矿床地质与水文地质条件的基础上,本文主要介绍了该矿床的一种洗孔工艺-氟化氢铵洗孔工艺。其基本原理是将氟化氢铵与硫酸注入到钻孔内,利用两者反应生成氢氟酸,溶解矿层中的二氧化硅胶体来改善渗透性。同时开展了现场试验,探索了该洗孔工艺的应用条件与效果。现场试验结果显示:该洗孔工艺效果良好,钻孔抽注液量比洗孔前得到大幅度提升。

关键词：洗孔工艺氟化氢铵地浸采铀

Advances in the Development of Gradient Scaffolds Made of Nano‑Micromaterials for Musculoskeletal Tissue Regeneration

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Nano-Micro Letters 2025年第3期17卷 455-500页

作者： Lei Fang Xiaoqi Lin Ruian Xu Lu Liu Yu zhang feng Tian Jiao Jiao Li Jiajia Xue Beijing Laboratory of Biomedical Materials Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China School of Biomedical Engineering Faculty of Engineering and ITUniversity of Technology SydneySydneyNSW 2007Australia

The intricate hierarchical structure of musculoskeletal tissues,including bone and interface tissues,necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered *** has led to growing interest in the development of gradient bone scaffolds with hierarchical structures mimicking the extracellular matrix of native tissues to achieve improved therapeutic *** on the anatomical characteristics of bone and interfacial tissues,this review provides a summary of current strategies used to design and fabricate biomimetic gradient scaffolds for repairing musculoskeletal tissues,specifically focusing on methods used to construct compositional and structural gradients within the *** latest applications of gradient scaffolds for the regeneration of bone,osteochondral,and tendon-to-bone interfaces are ***,the current progress of testing gradient scaffolds in physiologically relevant animal models of skeletal repair is discussed,as well as the challenges and prospects of moving these scaffolds into clinical application for treating musculoskeletal injuries.

关键词： Gradient scaffolds Musculoskeletal tissues Advanced manufacturing Biomaterials Tissue regeneration

Atmospheric reductive catalytic fractionation of lignocellulose integrated with one-pot catalytic conversion of carbohydrate yielding valuable lignin monomers and platform chemicals from corn straw

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Green Energy & Environment 2025年第1期10卷 161-172页

作者： Meng-Ying Liu Zhe-Hui zhang Xue-Qi Wang Qian Sun Chen zhang Yu Li Zhuohua Sun Katalin Barta feng Peng Tong-Qi Yuan State Key Laboratory of Efficient Production of Forest Resources Beijing Forestry UniversityBeijing100083China Beijing Key Laboratory of Lignocellulosic Chemistry Beijing Forestry UniversityBeijing100083China Department of Chemistry Organic and Bioorganic ChemistryUniversity of GrazHeinrichstrasse 28/II8010 GrazAustria

Developing a cost-effective and environmentally friendly process for the production of valuable chemicals from abundant herbal biomass receives great attentions in recent ***,taking advantage of the“lignin first”strategy,corn straw is converted to valuable chemicals including lignin monomers,furfural and 5-methoxymethylfurfural via a two steps *** key of this research lies in the development of a green and low-cost catalytic process utilizing magnetic Raney Ni catalyst and high boiling point ethylene *** utilization of neat ethylene glycol as the sole slovent under atmospheric conditions obviates the need for additional additives,thereby facilitating the entire process to be conducted in glass flasks and rendering it highly convenient for scaling *** the initial step,depolymerization of corn straw lignin resulted in a monomer yield of 18.1 wt%.Subsequently,in a dimethyl carbonate system,the carbohydrate component underwent complete conversion in a one-pot process,yielding furfural and 5-methoxymethylfurfural as the primary products with an impressive yield of 47.7%.

关键词： Atmospheric reductive catalytic fractionation Corn straw Ethylene glycol Raney Ni 5-Methoxymethylfurfural

纤维素纳米晶模板法制备有序介孔材料研究进展

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功能材料 2017年第3期48卷 3035-3041页

作者：黄兴冯坚张思钊冯军宗姜勇刚国防科学技术大学新型陶瓷纤维及其复合材料重点实验室长沙410073

纤维素纳米晶(cellulose nanocrysals,CNCs)是一种新型的模板材料,利用其自组装形成的手性结构可以实现CNCs模板法制备有序介孔材料。该法直接采用先驱体与具有自组装效应的CNCs复合并选择性去除模板或先驱体得到有序介孔,避免了预先制... 详细信息

纤维素纳米晶(cellulose nanocrysals,CNCs)是一种新型的模板材料,利用其自组装形成的手性结构可以实现CNCs模板法制备有序介孔材料。该法直接采用先驱体与具有自组装效应的CNCs复合并选择性去除模板或先驱体得到有序介孔,避免了预先制备介孔模板,缩短了工艺,并且对介孔结构可调性好。对应的介孔材料比表面积大、孔隙率高,介孔结构有序,为可控制备有序介孔材料提供了参考路径。介绍了CNCs的制备及其自组装,并且综述了近年来利用CNCs模板法制备有序介孔材料的研究进展,最后,对该领域未来研究方向进行了展望。

关键词：纤维素纳米晶模板法自组装介孔材料

An Efficient Boron Source Activation Strategy for the Low‑Temperature Synthesis of Boron Nitride Nanotubes

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Nano-Micro Letters 2025年第1期17卷 548-558页

作者： Ying Wang Kai zhang Liping Ding Liyun Wu Songfeng E Qian He Nanyang Wang Hui Zuo Zhengyang Zhou feng Ding Yue Hu Jin zhang Yagang Yao National Laboratory of Solid State Microstructures College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional Materialsand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093People’s Republic of China School of Electronic Information and Artificial Intelligence Shaanxi University of Science&TechnologyXian 710000People’s Republic of China College of Bioresources Chemical and Materials Engineering Shaanxi University of Science&TechnologyXian 710000People’s Republic of China Key Laboratory of Carbon Materials of Zhejiang Province College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325000People’s Republic of China Shenzhen Institutes of Advanced Technology Chinese Academy of SciencesShenzhen 518000People’s Republic of China College of Chemical and Molecular Engineering Peking UniversityBeijing 100871People’s Republic of China

Lowering the synthesis temperature of boron nitride nanotubes(BNNTs)is crucial for their *** primary reason for adopting a high temperature is to enable the effective activation of highmelting-point solid *** this study,we developed a novel approach for efficiently activating boron by introducing alkali metal compounds into the conventional MgO–B *** approach can be adopted to form various low-melting-point AM–Mg–B–O growth *** growth systems have improved catalytic capability and reactivity even under low-temperature conditions,facilitating the synthesis of BNNTs at temperatures as low as 850℃.In addition,molecular dynamics simulations based on density functional theory theoretically demonstrate that the systems maintain a liquid state at low temperatures and interact with N atoms to form BN *** findings offer novel insights into the design of boron activation and are expected to facilitate research on the low-temperature synthesis of BNNTs.

关键词： Boron nitride nanotubes Low-temperature Boron activation Density functional theory

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高浓度壳聚糖溶液酶解条件优化

食品工业科技 2018年第7期39卷 126-131页

作者：吴健锋张立彦华南理工大学食品科学与工程学院广东广州510640

在研究了壳聚糖酶的温度和p H稳定性的基础上,通过在溶解过程中加酶对高浓度壳聚糖溶液酶解条件进行优化,考查了加酶时间及加酶量对8%壳聚糖溶液酶解效率和酶解液粘度的影响,并对优化前后目标溶液中几种壳寡糖的含量进行分析。结果表明... 详细信息

在研究了壳聚糖酶的温度和p H稳定性的基础上,通过在溶解过程中加酶对高浓度壳聚糖溶液酶解条件进行优化,考查了加酶时间及加酶量对8%壳聚糖溶液酶解效率和酶解液粘度的影响,并对优化前后目标溶液中几种壳寡糖的含量进行分析。结果表明:壳聚糖酶在45~55℃及p H4.5~5.5范围内保持稳定;对8%壳聚糖溶液体系,在滴加盐酸浓度达到0.17 mol/L时,加入2 U/g壳聚糖的酶液,当盐酸浓度达到0.48 mol/L时再补加3 U/g壳聚糖的酶液,这种方案可以有效降低体系粘度并保持酶活力;薄层色谱和高效液相色谱分析结果表明,通过以上方式的优化,聚合度2~6的壳寡糖总含量及壳五糖和壳六糖的含量均显著增加(p<0.05),分别达到42.7、5.5和3.9 mg/m L,大大提高了生产效率和降低浓缩成本。

关键词：高浓度壳聚糖壳聚糖酶酶解条件优化壳寡糖