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The first two cases of transcatheter mitral valve repair with ARTO system in Asia

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World Journal of Emergency Medicine 2020年第1期11卷 33-36页

作者： Kai-da Ren Zhao-xia Pu Lei Yu Feng gao Li-han Wang Stella Ng Ju-bo jiang Hua-jun Li Yong Xu Wei He Min Yan Xian-bao Liu jian-an Wang Cardiovascular Department the Second Affiliated Hospital Zhejiang University School of Medicine

BACKGROUND:MAVERIC(Mitral Valve Repair Clinical Trial)validates the safety and effi cacy of the ARTO *** here report the fi rst two successful cases of utilizing the ARTO system in patients with symptomatic heart failure(HF)with functional mitral regurgitation(FMR)in ***:Two patients,aged 70 and 63,had severe HF with *** echocardiography confirmed that the left ventricular ejection fractions were less than 50%with severe mitral regurgitation(MR)in both *** drug treatment could not mitigate their ***,we used the ARTO system to repair the mitral valve for these patients on March 5 and 6,2019,***:Mitral valve repairs using the ARTO system were successfully performed under general anaesthesia for these two *** was decreased immediately after the procedures in both *** 30-day and 3-month transthoracic echocardiography(TTE)revealed a moderate to severe MR in both patients,and the New York Heart Association(NYHA)scales were also partially ***:The first two cases in Asia indicate that the ARTO system is feasible for patients with heart failure with FMR,and the patient selection appears to be crucial.

关键词： Mitral regurgitation Mitral valve repair ARTO system

Multi-hop teleportation in a quantum network based on mesh topology

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Frontiers of physics 2018年第5期13卷 311-317页

作者： Xiao-Qin gao Zai-Chen Zhang Bin Sheng National Mobile Communications Research Laboratory Southeast University Nanjing 210096 China

In this paper, we propose a mesh-topology-based multi-hop teleportation scheme for a quantum net- work. By using the proposed scheme, quantum communication can be realized between two arbitrary nodes, even when they do not share a direct quantum channel. Einstein-Podolsky-Rosen pairs are used as quantum channels. The source node （initial sender） and all intermediate nodes make Bell measurements independently. They send the results to the destination node （final receiver） by classical channels. The quantum state can be determined from the Bell measurement result, and only the desti- nation node is required for simple unitary transformation. This method of simultaneous measurement contributes significantly to quantum network by reducing the hop-by-hop transmission delay.

关键词： multi-hop teleportation quantum network mesh topology

A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasis

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Protein & Cell 2023年第12期14卷 888-907页

作者： Daoyuan Huang Yuesheng Zuo Chen Zhang Guoqiang Sun Ying Jing Jinghui Lei Shuai Ma Shuhui Sun Huifen Lu Yusheng Cai Weiqi Zhang fei gao Andy Peng Xiang Juan Carlos Izpisua Belmonte Guang-Hui Liu Jing Qu Si Wang Advanced Innovation Center for Human Brain Protection National Clinical Research Center for Geriatric DisordersXuanwu Hospital Capital Medical UniversityBeijing100053China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Aging Translational Medicine Center International Center for Aging and CancerBeijing Municipal Geriatric Medical Research CenterXuanwu HospitalCapital Medical UniversityBeijing 100053China State Key Laboratory of Membrane Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Beijing Institute for Stem Cell and Regenerative Medicine Beijing 100101China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academy of SciencesBeijing 100101China Institute for Stemcell and Regeneration CAsBeijing100101China China National Center for Bioinformation Beijing 100101China The Fifth People's Hospital of Chongqing Chongqing 400062China 11Sino-Danish College University of Chinese Academy of SciencesBeijing 101408China Sino-Danish Center for Education and Research Beijing 101408China Center for Stem Cell Biology and Tissue Engineering Key Laboratory for Stem Cells and Tissue EngineeringMinistry of EducationSun Yat-sen UniversityGuangzhou510000China Department of Biochemistry Zhongshan School of MedicineSun Yat-sen UniversityGuangzhou 510000China Altos Labs Inc.San DiegoCA 92121USA and Aging Biomarker Consortium China

The testis is pivotal for male reproduction,and its progressive functional decline in aging is associated with ***,the regulatory mechanism underlying primate testicular aging remains largely ***,we resolve the aging-related cellular and molecular alterations of primate testicular aging by establishing a single-nucleus transcriptomic ***-expression patterns along the spermatogenesis trajectory revealed molecular programs associated with attrition of spermatogonial stem cell reservoir,disturbed meiosis and impaired spermiogenesis along the sequential ***,Sertoli cell was identified as the cell type most susceptible to aging,given its deeply perturbed age-associated transcriptional ***,downregulation of the transcription factor Wilms'Tumor 1(WTi),essential for Sertoli cell homeostasis,was associated with accelerated cellular senescence,disrupted tight junctions,and a compromised cell identity signature,which altogether may help create a hostile microenvironment for ***,our study depicts in-depth transcriptomic traits of non-human primate(NHP)testicular aging at single-cell resolution,providing potential diagnostic biomarkers and targets for therapeutic interventions against testicular aging and age-related male reproductive diseases.

关键词： single-nucleus RNA sequencing primate testis aging WT1

Numerical simulation for macrosegregation in direct-chill casting of 2024 aluminum alloy with an extended continuum mixture model

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Transactions of Nonferrous Metals Society of China 2018年第5期28卷 1007-1015页

作者： Hai-jun LUO Wan-qi JIE Zhi-ming gao Yong-jian ZHENG State Key Laboratory of Solidification Processing Northwestern Polytechnical University Xi＇an 710072 China Chair of Simulation and Modeling of Metallurgical Processes Montan Universitaet Leoben 8700 Leoben Austria

An extended continuum mixture model for macrosegregation is applied to predicting Cu and Mg segregation in large-size ingot of 2024 aluminum alloy during direct chill casting（DC）. A microsegregation model using the approximate phase diagram data was coupled with macroscopic transport equations for macrosegregation profiles. Then, the impacts of transport mechanisms on the formation of macrosegregation were discussed. It is found that copper and magnesium have a similar segregation configuration from the billet center to surface. Negative segregation is observed in the centerline and subsurface, whereas positive segregation is obtained in the surface and somewhat underestimated positive segregation in the middle radius. Further, the discrepancy between the predicted and experimental results was discussed in detail. The results show that the magnesium to some extent alleviates the copper segregation in ternary alloy, compared with that in binary alloy. The predicted results show good agreement with measured experimental data obtained from literatures.

关键词： direct-chill casting macrosegregation numerical simulation continuum model 2024 aluminum alloy

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基于路由表分析的路由一致性检查

小型微型计算机系统 2000年第5期21卷 458-461页

作者：高毓航龚俭东南大学计算机系南京210096

本文提出了一种新的路由一致性检查方法 ,它基于对路由器中网络运行最新痕迹的分析实现 ,可更为合理地给出大规模互联网络的连通性信息 .文中详细地介绍了该方法的设计思想 ,以及采用 Java语言和 Web技术的实现手段和实现技巧 .

关键词：路由表路由选择一致性检查计算机网络

利用真空预压实测孔隙水压力推算土体固结度的计算方法探讨

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中国港湾建设 2005年第1期25卷 13-15页

作者：侯健飞天津港建设公司天津300456

根据大量真空预压实际工程中孔隙水压力观测结果,提出了一套由实测孔隙水压力时程曲线,直接确定总超静水压力,进而计算孔隙水应力固结度的方法,回避了理论计算时被测点的应力增加总值、加固过程固结系数变化以及固结理论的基本假设和实... 详细信息

根据大量真空预压实际工程中孔隙水压力观测结果,提出了一套由实测孔隙水压力时程曲线,直接确定总超静水压力,进而计算孔隙水应力固结度的方法,回避了理论计算时被测点的应力增加总值、加固过程固结系数变化以及固结理论的基本假设和实际地基差异等因素造成的理论固结度与实际情况的差异。该方法经实际应用,效果较好。

关键词：真空预压法孔隙水压力孔隙水压力固结度计算

吻合口加固修补组件背衬面料的选择与防漏性能评价

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纺织学报 2021年第4期42卷 69-73,79页

作者：蒋君莹高晶张剑东华大学纺织学院上海201620 上海长征医院普外科上海200001

针对外科手术中,吻合器吻合常会出现脆弱组织被吻合钉撕裂,产生吻合口瘘、吻合口出血、漏气以及渗液等问题,设计了一种吻合口加固修补组件使加固片平整地覆盖在吻合口上,为待修补组织提供足够的强度。首先对加固修补组件进行复合设计,... 详细信息

针对外科手术中,吻合器吻合常会出现脆弱组织被吻合钉撕裂,产生吻合口瘘、吻合口出血、漏气以及渗液等问题,设计了一种吻合口加固修补组件使加固片平整地覆盖在吻合口上,为待修补组织提供足够的强度。首先对加固修补组件进行复合设计,并对背衬面料和修补组件的性能进行评价,最后通过体外肺部漏气实验对吻合口加固修补组件的防漏性能进行模拟测试。结果表明:当锦纶/氨纶(80/20)为纬平针结构时,其具有适宜吻合口加固修补组件背衬面料的性能;加固修补组件体外肺部实验表明,其可有效预防肺部吻合口渗漏,对于预防术后吻合口并发症提供了安全有效的措施。

关键词：吻合口瘘加固修补组件背衬面料体外模拟实验防漏性能医用纺织品

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生态文明建设要点探索

生态与农村环境学报 2014年第5期30卷 545-551页

作者：高吉喜栗忠飞环境保护部南京环境科学研究所江苏南京210042 西南林业大学环境科学与工程学院云南昆明650224

生态文明是继工业文明之后更高层次的文明,而环境保护是生态文明建设的主要内容。在综合分析生态文明建设的目标、任务、本质、路径、关键和保障等理论问题的基础上,提出生态文明建设的要点:生态文明建设的目标是人与自然和谐,核心任务... 详细信息

生态文明是继工业文明之后更高层次的文明,而环境保护是生态文明建设的主要内容。在综合分析生态文明建设的目标、任务、本质、路径、关键和保障等理论问题的基础上,提出生态文明建设的要点:生态文明建设的目标是人与自然和谐,核心任务是生态环境保护,本质是发展方式的转变,关键是科技创新驱动,保障是制度建设。认为通过生态文明建设,可最终实现人类社会的可持续发展。

关键词：生态文明建设生态环境人与自然

二阶椭圆边值问题的一种新型稳定化非协调混合有限元方法

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工程数学学报 2013年第6期30卷 846-854页

作者：荆菲菲苏剑陈浩西安交通大学数学与统计学院西安710049 西安交通大学能动学院西安710049

基于Poisson方程的新型混合变分形式,本文采用最低等阶非协调有限元对,并利用局部Gauss积分之差对其离散格式加以稳定,建立了求解Poisson方程的新型稳定化非协调混合有限元方法,通过验证离散的LBB条件证明了有限元逼近解的存在惟一性,... 详细信息

基于Poisson方程的新型混合变分形式,本文采用最低等阶非协调有限元对,并利用局部Gauss积分之差对其离散格式加以稳定,建立了求解Poisson方程的新型稳定化非协调混合有限元方法,通过验证离散的LBB条件证明了有限元逼近解的存在惟一性,以及该非协调有限元方法下压力关于L2,H1范数的最优误差估计,通量关于L2范数的次优误差估计.最后,给出数值算例验证了本文理论分析的正确性与所给方法的有效性.

关键词： Poisson方程混合变分形式非协调有限元稳定化误差估计