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Predicting protein subchloroplast locations:the 10th anniversary

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Frontiers of Computer Science 2021年第2期15卷 1-11页

作者： jian SUN Pu-Feng du College of Intelligence and Computing Tianjin UniversityTianjin300350China

Chloroplast is a type of subcellular organelle in green plants and *** is the main subcellular organelle for conducting photosynthetic *** proteins,which localize within the chloroplast,are responsible for the photosynthetic process at molecular *** chloroplast can be further divided into several *** in different compartments are related to different steps in the photosynthetic *** the molecular function of a protein is highly correlated to the exact cellular localization,pinpointing the subchloroplast location of a chloroplast protein is an important step towards the understanding of its role in the photosynthetic *** process for determining protein subchloroplast location is always costly and time ***,computational approaches were developed to predict the protein subchloroplast locations from the primary *** the last decades,more than a dozen studies have tried to predict protein subchloroplast locations with machine learning *** sequence features and various machine learning algorithms have been introduced in this research *** this review,we collected the comprehensive information of all existing studies regarding the prediction of protein subchloroplast *** compare these studies in the aspects of benchmarking datasets,sequence features,machine learning algorithms,predictive performances,and the implementation *** summarized the progress and current status in this special research *** also try to figure out the most possible future works in predicting protein subchloroplast *** hope this review not only list all existing works,but also serve the readers as a useful resource for quickly grasping the big picture of this research *** also hope this review work can be a starting point of future methodology studies regarding the prediction of protein subchloroplast locations.

关键词： subchloroplast locations sequence features performance measures online services machine learning

Use of liquid crystal to study the interactions of alkyl polyglycosides with gelatin and bovine serum albumin

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Chinese Chemical Letters 2016年第6期27卷 852-856页

作者： Zhi-jian Liao Si-Nan du yang Luo Fang Zuo jian-Bin Luo College of Chemistry & Environment Protection Engineering Southwest University for Nationalities

In this study, liquid crystal（LC） was used to study the interactions of alkyl polyglycosides（APG） with gelatin and bovine serum albumin（BSA） at the LC-aqueous interface. The LC easily undergo an orientational transition from a homeotropic to a planar state after proteins were in contact to the LCaqueous interface decorated with APG, thus inducing an optical change from dark to bright. The optical image analysis reveals that the rearrangement rate of APG monolayer is tightly dependent on the concentration and chemical structure of the protein of interest. For example, the rearrangement rate of APG monolayer increases with an increasing gelatin concentration. We also find that the chemical structure of the proteins has a significant impact on the difference in the growth behavior of bright domains in LC.

关键词： Liquid crystal Alkyl polyglycoside Optical image Orientational transition

Reducing defect of inorganic perovskite film by sulphur-containing Lewis base for robust photodetectors

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Journal of Energy Chemistry 2021年第10期30卷 163-169,I0005页

作者： jian du Jialong duan Xiya yang Qingwei Zhou Yanyan duan Tingting Zhang Qunwei Tang Institute of New Energy Technology College of Information Science and TechnologyJinan UniversityGuangzhou 510632GuangdongChina State Centre for International Cooperation on Designer Low-Carbon and Environmental Material(SCICDLCEM) School of Materials Science and EngineeringZhengzhou UniversityZhengzhou 450001HenanChina Guangdong Provincial Key Laboratory of Development and Education for Special Needs Children Lingnan Normal UniversityZhanjiang 524048GuangdongChina

Sluggish charge transfer in perovskite film induced by inherent defects such as uncoordinated Pb2+undoubtedly hinders the rapid response of self-powered photovoltaic-typed *** on interaction between Lewis acids and bases,herein,we employ thiourea molecule as a multifunctional Lewis base to significantly improve the quality of all-inorganic CsPbIBr2 perovskite *** careful characterizations,the quality of perovskite film has been well *** from the reduced defect and the reinforced the interfacial charge extraction owing to the strong interaction between uncoordinated Pb2+ions and the-C=S groups in thiourea and the formation of hydrogen bond at perovskite/TiO_(2) interface,an enhanced responsivity of 0.335 A W-1 and specific detectivity of 3.92×10^(12) Jones has been achieved for the self-powered,carbon-electrode based photodetector,which is comparable to the state-of-theart device based on CsPbIBr2 *** importantly,the device free of encapsulation remains 82.8%of initial performance after storage over 56 days in ambient atmosphere,promoting the practical deployment of perovskite products.

关键词： All-inorganic perovskite Self-powered photodetector Defect passivation Charge transfer Stability

Corrosion Mechanism of 5083 Aluminum Alloy in Seawater Containing Phosphate

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Journal of Ocean University of China 2021年第2期20卷 372-382页

作者： WANG Jiaming yang Haodong du Min HOU jian PENG Wenshan LIN Cunguo The Key Laboratory of Marine Chemistry Theory and Technology Ministry of EducationCollege of Chemistry and Chemical EngineeringOcean University of ChinaQingdao 266100China State Key Laboratory for Marine Corrosion and Protection Luoyang Ship Material Research Institute(LSMRI)Qingdao 266237China

As a material with good corrosion resistance,5083 aluminum alloy has a great application prospect in marine *** this work,the corrosion characteristics of 5083 aluminum alloy in seawater containing phosphate were investigated with Potentiodynamic Polarization,Electrochemical Impedance Spectroscopy (EIS),Scanning Electron Microscope (SEM),Energy Dispersive Spectroscopy Analysis (EDSA),X-ray Photoelectron Spectroscopy (XPS) and Laser Confocal *** results indicated that the effects of phosphate in seawater were ***,phosphate slightly accelerated the corrosion of 5083 in seawater in the early stage of ***_4~(2-)competed with OH~-in the adsorption process on the alloy surface,which weakened the contact between OH~-and Al~(3+)near the interface of the alloy,and inhibited the formation as well as the self-repair of the passive film,thus accelerating the activation dissolution *** with the natural seawater,the charge transfer resistance of 5083 in the seawater containing phosphate decreased faster during the early stage of corrosion,and the corrosion current density i_(corr) was higher in seawater containing *** the other hand,the addition of phosphate would not affect the cluster distribution of the second phase of 5083 in seawater,but it changed the composition of the corrosion product layer and had an obvious inhibitory effect on the local corrosion of 5083 in *** 16-day exposure,shallower and more sparsely distributed pits could be observed on the derusted surface of 5083 in the seawater containing phosphate,and the pitting coefficient in the seawater containing phosphate was significantly lower than that in natural *** reduction of pitting tendency could be realized mainly through two ***,the HPO_4~(2-)adsorbed on the surface of the passive film in the early stage of corrosion and repeled the corrosive anions such as Cl~-.Second,phosphate participated in the construction of th

关键词： 5083 aluminum alloy seawater containing phosphate pitting corrosion passive film Cl~-

Vagus nerve stimulation in cerebral stroke:biological mechanisms,therapeutic modalities,clinical applications,and future directions

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Neural Regeneration Research 2024年第8期19卷 1707-1717页

作者： Li du Xuan He Xiaoxing Xiong Xu Zhang Zhihong jian Zhenxing yang Department of Anesthesiology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina Department of Neurosurgery Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Stroke is a major disorder of the central nervous system that poses a serious threat to human life and quality of *** stro ke victims are left with long-term neurological dysfunction,which adversely affects the well-being of the individual and the broader socioeconomic ***,poststroke brain dysfunction is a major and difficult area of *** nerve stimulation is a Food and Drug Administration-approved exploratory treatment option for autis m,refractory depression,epilepsy,and Alzheimer’s *** is expected to be a novel therapeutic technique for the treatment of stroke owing to its association with multiple mechanisms such as alte ring neurotransmitters and the plasticity of central neuro *** animal models of acute ischemic stroke,vagus nerve stimulation has been shown to reduce infarct size,reduce post-stroke neurological damage,and improve learning and memory capacity in rats with stroke by reducing the inflammatory response,regulating bloodbrain barrier permeability,and promoting angiogenesis and *** present,vagus nerve stimulation includes both invasive and non-invasive vagus nerve *** studies have found that invasive vagus nerve stimulation combined with rehabilitation therapy is effective in im proving upper limb motor and cognitive abilities in stroke *** clinical studies have shown that non-invasive vagus nerve stimulation,including ear/ce rvical vagus nerve stimulation,can stimulate vagal projections to the central nervous system similarly to invasive vagus nerve stimulation and can have the same *** this paper,we first describe the multiple effects of vagus nerve stimulation in stroke,and then discuss in depth its neuroprotective mechanisms in ischemic *** go on to outline the res ults of the current major clinical applications of invasive and non-invasive vagus nerve ***,we provide a more comprehensive evaluation of the advantages and disadvantages of di

关键词： cerebral stroke neuroplasticity non-invasive vagus nerve stimulation rehabilitation vagus nerve stimulation

A novel active-passive protection strategy endows carbonyl iron with excellent intelligent anti-corrosion and microwave absorption dual functional characteristics

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Nano Research 2025年第1期18卷 487-500页

作者： Wei Tian Quanyuan Feng Linbo Zhang Yinfan Liu Xian jian Longjiang Deng Institute of Microelectronics School of Information Science and TechnologySouthwest Jiaotong UniversityChengdu 611756China National Engineering Researching Centre of Electromagnetic Radiation Control Materials Key Laboratory of Multi-Spectral Absorbing Materials and Structures of Ministry of EducationState Key Laboratory of Electronic Thin Films and Integrated DevicesSchool of Electronic Science and EngineeringUniversity of Electronic Science and Technology of ChinaChengdu 611731China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 611731China The yangtze Delta Region Institute(Huzhou)&School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaHuzhou 313001China

Carbonyl iron absorbers(CI)face significant challenges in practical applications,such as corrosion,interface bonding failure,detachment,and high maintenance ***,we have developed intelligent self-healing technology based on proactive/passive mechanisms via in situ synthesis of self-healing factors(polydopamine/benzotriazole(PDA/BTA))and physical barrier layers(SiO_(2)/1,1,1,3,3,3-hexamethyl disilazane,SiO_(2)/HMDS)to enhance corrosion resistance,while also being compatible with efficient microwave absorption *** unique multiscale structure gives full play to the utilization of the roles of each functional layer,including the intelligent self-healing features of PDA/BTA,physical shielding and spatial confinement characteristics of SiO_(2)/HMDS,and magnetic-dielectric synergistic mechanism resulted from the good impedance matching characteristics,the conduction loss,the interfacial polarization loss and natural *** asfabricated composites achieved an exceptional minimum reflection loss value of-55.4 dB at 10.7 GHz and the effective absorption band of 7.6 ***,it still exhibits obvious self-healing and corrosion resistance characteristics after 360 h corrosion treatment,ascribed to the self-healing mechanism of PDA/BTA and the blocking intervention effect of SiO_(2)/*** work is considered to pave the way for the synthesis of high-performance magnetic absorbers,especially in enhancing their intelligent self-healing ability in corrosive environments.

关键词： microwave absorption intelligent self-healing technology carbonyl iron multiscale structure magneticdielectric synergistic mechanism

Snake-worm: A Bi-modal Locomotion Robot

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Journal of Bionic Engineering 2022年第5期19卷 1272-1287页

作者： Zhouwei du Hongbin Fang jian Xu School of Aerospace Engineering and Applied Mechanics Tongji UniversityShanghai 200092China Institute of AI and Robotics Fudan UniversityShanghai 200433China Engineering Research Center of AI and Robotics Ministry of EducationFudan UniversityShanghai 20043China Shanghai Engineering Research Center of AI and Robotics Fudan UniversityShanghai 200433China

Inspired by the morphology characteristics and the locomotion mechanisms of the earthworm,and the snakes’morphology characteristics and motivated by the demands for multi-modal locomotion robots in variable working environments,this paper presents a novel bi-modal robot named as Snake-Worm Locomotion Robot(SWL-Robot).Two fundamentally different locomotion mechanisms,the earthworm’s peristaltic rectilinear locomotion and the snake’s lateral undulation,are synthesized in the SWL-Robot *** detail,the SWL-Robot consists of six earthworm-like body segments interconnected by rotational joints and a head segment equipped with a couple of independently driven *** actuating the segments following a peristaltic wave-like gait,the robot as a whole could perform earthworm-like rectilinear *** robot could also perform snake-like undulatory locomotion driven by differential motions of the wheels at the head *** understand the relationship between the design parameters and the robotic locomotion performance,kinematic models of the SWL-Robot corresponding to the two locomotion modes are *** locomotion behaviors of the SWL-Robot are achieved,including the peristaltic locomotion inside a tube,multiple planar motions on a flat surface,and a hybrid motion that switches between the tube and the flat *** shows that the measured trajectories of the SWL-Robot agree well with the theoretical *** SWL-Robot is promising to be implemented in tasks where both tubular and flat environments may be encountered.

关键词： Multi-modal locomotion Peristaltic locomotion Planar locomotion Worm-like robot Snake-like robot

The performance of China's biomedical innovation:a scientometric analysis

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Science China(Life Sciences) 2016年第10期59卷 1074-1082页

作者： Xiaoli Tang jian du Institute of Medical Information & Library Chinese Academy of Medical Sciences

Recognizing the importance of innovation in science and technology （S＆T） as a driver of continued economic growth, China has introduced new policies to facilitate and encourage innovation and made significant progress in S＆T innovation in the past decade. The total volume of innova- tion resources is steadily growing. Commensurate with its status as the second largest economy in the world, China ranks second globally now in research and development （R＆D） investment.

关键词：科技创新计量分析生物医学中国绩效研究与开发持续增长资源总量

Characterization of a native whitefly vitellogenin gene cDNA and its expression pattern compared with two invasive whitefly cryptic species

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Journal of Integrative Agriculture 2016年第8期15卷 1808-1815页

作者： GUO jian-yang du Yu-ping WAN Fang-hao YE Gong-yin Key Laboratory of Agricultural Entomology Ministry of Agriculture/Institute of Insect Sciences Zhejiang University State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection Chinese Academy of Agricultural Sciences

supported by grants from the National Basic Research Program of China （2014CB138404）;the China National Science Fund for Innovative Research Groups of Biological Control （31321063）;the National Basic Research Program of China （973 Program, 2009CB119203）;the National Natural Science Foundation for Young Scientists in China （31101674）

关键词： vitellogenin gene Bemisia tabaci MED Asia Ⅱ 1 MEAM1 vitellogenesis displacement