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Biomedical and Environmental Sciences 2023年第6期36卷 553-556页

作者： gu jian Chang SONG Ji Wu LIU Yun WANG Xiao Lan XU Shuang Shuang ZHANG Liang Liang LIU Yun Xia DING Gang School of Stomatology Weifang Medical UniversityWeifang 261053ShandongChina Department of Stomatology Weifang People’s HospitalFirst Affiliated Hospital of Weifang Medical UniversityWeifang 261053ShandongChina Department of Dentistry Affiliated Hospital of Weifang Medical UniversityWeifang 261035ShandongChina

Oral cancer is the most common malignant tumor of the head and *** is characterized by high rates of recurrence and distant metastasis and usually has a poor *** advances in cancer diagnosis and treatment,the overall ... 详细信息

关键词： diagnosis cancer Cancer

Level Statistics for the Nilsson Single-Particle Levels

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Chinese Physics Letters 2010年第3期27卷 52-55页

作者：陈芳祁周先荣顾建中 Department of Physics and Institute of Theoretical Physics and Astrophysics Xiamen University Xiamen 361005 China Institute of Atomic Energy P.O. Box 275(18) Beijing 102413

We perform level statistics of the Nilsson single-particle levels. The effects of the l2 and l ＆#12539; s; s terms are discussed as well as their interplay with the deformations. The results show that when the l2 term is added to the harmonic oscillator potential, chaotic motion occurs. The strength ranges of the l2 term in which chaotic motion exists are related to the deformation of the harmonic oscillator potential. The calculations of the localization length in different bases demonstrate that it is the spherical or axial symmetries that govern the chaotic motion. The degree of chaoticity increases significantly with the l ＆#12539; s; s term included.

关键词： Nuclear physics

Superhydrophilic nickel hydroxide ultrathin nanosheets enable high-performance asymmetric supercapacitors

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Rare Metals 2024年第1期43卷 138-147页

作者： Yi-Ran Wang Fei Zhang jian-Min gu Xiao-Yu Zhao Ran Zhao Xing Wang Tian-Hui Wu Jing Wang Ji-Dong Wang De-Song Wang State Key Laboratory of Metastable Materials Science and Technology(MMST) Hebei Key Laboratory of Applied ChemistryYanshan UniversityQinhuangdao 066004China Department of Food and Pharmaceutical Engineering Suihua UniversitySuihua 152000China School of Chemical Science and Engineering Tongji UniversityShanghai 200092China School of Sciences Hebei University of Science and TechnologyShijiazhuang 050018China

Superhydrophilic surfaces have been applied for supercapacitor;however,during energy storage reaction,how the wettability affects the process of electrochemical reaction specifically is still ***,we demonstrate superhydrophilic surface for promotion of electrochemical reactions by liquid affinity and further explain the mechanism,where the transition of the wettability state caused by the change in surface free energy is the main reason for the obvious increase in specific *** citric acid assistance strategy,an intrinsically hydrophobic Ni(OH)_(2)thick nanosheets(HNHTNs,16 nm)can be transitioned into superhydrophilic Ni(OH)_(2)ultrathin nanosheets(SNHUNs,6.8 nm),where the water contact angle was 0°and the surface free energy increased from 8.6to 65.8 mN·m^(-1),implying *** with HNHTNs,the specific capacitance of SNHUNs is doubled:from 1230 F·g^(-1)(HNHTNs)to 2350 F·g^(-1)(2A·g^(-1))and,even at 20 A·g^(-1),from 833 F·g^(-1)(HNHTNs)to 1670 F·g^(-1).The asymmetric capacitors assembled by SNHUNs and activated carbon show 52.44 Wh·kg^(-1)at 160W·kg^(-1)and excellent stability with~90%retention after5000 cycles(~80%retention after 9500 cycles).The promotion of electrochemical performances is ascribed to the change of surface wettability caused by surface free energy,which greatly increase affinity of electrode to the surrounding liquid environment to reduce the interface resistance and optimize the electron transport path.

关键词： Asymmetric supercapacitor Superhydrophilic interface Transition metal hydroxides Ultrathin nanosheets High specific capacitance

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水锤作用下饱和地基蓄排水隧道的动力响应

岩土力学 2024年第12期45卷 3802-3814页

作者：黄超钱建固同济大学地下建筑与工程系上海200092 同济大学土木工程防灾减灾全国重点实验室上海200092 新疆大学建筑工程学院新疆乌鲁木齐830047

针对饱和土地基中深埋蓄排水隧道在水锤作用下的三维动力响应问题,建立了流体-衬砌-饱和土地基系统的频域有限元与边界元耦合模型。隧道内流体视为无黏性、微可压缩性流体,将隧道衬砌结构模拟为弹性介质,用弹性多孔介质模拟饱和土地基... 详细信息

针对饱和土地基中深埋蓄排水隧道在水锤作用下的三维动力响应问题,建立了流体-衬砌-饱和土地基系统的频域有限元与边界元耦合模型。隧道内流体视为无黏性、微可压缩性流体,将隧道衬砌结构模拟为弹性介质,用弹性多孔介质模拟饱和土地基。采用频域有限元法分别求解隧道内流体和衬砌的动力控制方程;采用频域边界元方法求解饱和土地基的动力控制方程。基于流体-衬砌接触面和衬砌-饱和土地基接触面的位移一致、面力平衡及完全不透水边界条件,实现了频域有限元与边界元模型的耦合求解。与以往研究的对比验证了新建模型的正确性。利用该模型计算了蓄排水隧道在水锤作用下的内水压(水锤荷载)和周边饱和土体的位移及孔隙水压力响应。结果表明:(1)水锤作用下的动力响应呈现出显著的周期性和衰减性;(2)土体径向位移幅值显著大于轴向位移幅值;(3)将地基简化为单相弹性介质会导致动力响应评估不准确;(4)水锤作用会对隧道周边广大的区域内造成显著的影响;(5)土体的渗透性越差,隧道内流体压力、土体位移和孔隙水压力的峰值越小。

关键词：水锤蓄排水隧道有限元-边界元饱和土动力响应

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基于微观渗流机理的宏观油藏数值模拟研究

中国石油大学学报（自然科学版） 2006年第1期30卷 77-81,85页

作者：谷建伟中国石油大学石油工程学院山东东营257061

处于高含水开发期油藏的剩余油分布主要受流体性质和岩石孔隙结构的影响,而经典数值模拟并没有考虑微观孔喉特征的影响。为此建立了描述微观孔喉特征的地层孔隙网络模型,并对构成网络的基本连线单元进行改进,使网络模型能更细致地描述... 详细信息

处于高含水开发期油藏的剩余油分布主要受流体性质和岩石孔隙结构的影响,而经典数值模拟并没有考虑微观孔喉特征的影响。为此建立了描述微观孔喉特征的地层孔隙网络模型,并对构成网络的基本连线单元进行改进,使网络模型能更细致地描述油水分布特征和水驱油微观机理。利用逾渗理论计算了基于微观渗流机理的相对渗透率曲线,并将其应用到经典数值模拟计算中,实现了微观渗流机理与宏观数值模拟计算的结合。实例分析表明,利用该数值模拟计算方法得到的基于微观特征的剩余油分布更符合地下实际流体分布,其结果可为调剖堵水、化学驱提供技术参数。

关键词：微观渗流机理逾渗理论网络模型剩余油分布高含水开发期宏观油藏数值模拟

Protective effect of inactivated hepatitis A vaccine against the outbreak of hepatitis A in an open rural community

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World Journal of Gastroenterology 2008年第17期14卷 2771-2775页

作者： Yue-Gen Shen Xie-Jun gu jian-Hong Zhou Xiuzhou DistrictConter for Disease Control and Prevention Jiaxing 314001Zhejiang Province China

AIM： To evaluate the protective effect of inactivated hepatitis A vaccine （Healive） against hepatitis A outbreak in an emergency vaccination campaign. METHODS： During an outbreak of hepatitis A in Honghe Town, Xiuzhou District, Jiaxing City, Zhejiang Province, two nonrandomized controlled trials were conducted in September 2006. The first trial was to vaccinate 108 anti-HAV negative individuals with close contacts of the patients from September with 1 dose of an inactivated hepatYds A vaccine, HeaUve. The control group comprised of 115 individuals with close contacts of the patients before September. The second trial was to vaccinate 3365 primary and secondary school students who volunteered to receive a dose of Healive and 2572 students who did not receive Healive serving as its controls. An epidemiological survey was conducted to evaluate the pmtectk, e efficacy of the vaccine. RESULTS： A total of 136 hepatitis A cases were reported during an outbreak that started in June, peaked in August and September, and ended after December of 2006. After a massive vaccination of school children in September, the number of cases declined significantly. No hepatitis A was detected in the 108 vaccinated individuals with dose contacts of patients, whereas 4 cases of hepatitis A were found in the controls. The infection rate of hepatitis A was not significantly different in the individuals with close contacts of patients whether or not they received the vaccine （P = 0.122）. No hepatitis A was detected in the 3365 students who received the vaccine, four cases of hepatitis A were found in the controls. The infection rate of students with or without vaccination was significantly diffeent in the students who received the vaccine （0/3365 vs 4/2572, P = 0.035）. The protective efficacy of the vaccine was 100%.CONCLUSION： Inactivated hepatitis A vaccine demonstrates a good protective effect against an outbreak of hepatitis A.

关键词： Hepatitis A Outbreak Inactivated hepatitis Avaccine Emergency vaccination Protective efficacy

Provocation Test-Confirmed Chlorhexidine-Induced Anaphylaxis in Dental Procedure

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Chinese Medical Journal 2018年第23期131卷 2893-2894页

作者： jian-Qing gu Shuang Liu Yu-Xiang Zhi Department of Allergy Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Institute of Clinical Medicine Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

To the Editor:Chlorhexidine (CHL)is a widely used broad-spectrum antiseptic and *** used as a topical antimicrobial agent,CHL is now available in different forms and is present in various settings.[1] CHL has the potential to cause Type I and Type IV hypersensitivity reactions,varying from mild cutaneous reactions to anaphylaxis.[2] An increased recognition of CHL-induced hypersensitivity parallels the increased use of CHL in medical care and the increased awareness of allergy.[3]

关键词： Anaphylaxis Dental Procedure

Olfactory ensheathing cells promote nerve regeneration and functional recovery after facial nerve defects

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Neural Regeneration Research 2019年第1期14卷 124-131页

作者： jian gu He Xu Ya-Ping Xu Huan-Hai Liu Jun-Tian Lang Xiao-Ping Chen Wei-Hua Xu Yue Deng Jing-Ping Fan Department of Otolaryngology Shanghai Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Department of Otolaryngology Head and Neck Surgery Changzheng Hospital Second Military Medical University Department of Otolaryngology Head and Neck Surgery Gongli Hospital Second Military Medical University

Olfactory ensheathing cells from the olfactory bulb and olfactory mucosa have been tbund to increase axonal sprouting and pathfinding and promote the recovery of vibrissae motor performance in facial nerve transection injured rats. However, it is not yet clear whether olfactory ensheathing cells promote the reparation of facial nerve defects in rats. In this study, a collagen sponge and silicone tube neural conduit was implanted into the 6-mm defect of the buccal branch of the facial nerve in adult rats. Olfactory ensheathing cells isolated from the olfactory bulb of newborn Sprague-Dawley rats were injected into the neural conduits connecting the ends of tile broken nerves, the morphology and function of the regenerated nerves were compared between the rats implanted with olfactory ensheathing cells with the rats injected with saline. Facial paralysis was assessed. Nerve electrography was used to measure facial nerve-induced action potentials. Visual inspection, anatomical microscopy and hematoxylin-eosin staining were used to assess the histomorphology around the trans planted neural conduit and the morphology of the regenerated nerve. Using fluorogold retrograde tracing, toluidine blue staining and lead uranyl acetate staining, we also measured the number of neurons in the anterior exterior lateral f：acial nerve motor nucleus, the number of myelinated nerve fibers, and nerve fiber diameter and myelin sheath thickness, respectively. After surgery, olfactory ensheathing cells de- creased facial paralysis and the latency of the facial nerve-induced action potentials. There were no differences in the general morphology of the regenerating nerves between the rats implanted with olfactory ensheathing cells and the rats injected with saline. Between-group results showed that olfactory ensheathing cell treatment increased the number of regenerated neurons, improved nerve fiber morphology, and increased the number of myelinated nerve fibers, nerve fiber diameter, and myel

关键词： nerve regeneration facial nerve defects olfactory ensheathing cells nerve fibers myelination neurons nerve muscle action potentials facial nerve motor nucleus neural regeneration

A NOVEL REDUCTIVE TETRAALLYLATION OF PYRIDINE

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Chinese Chemical Letters 1995年第10期6卷 833-834页

作者： Xian Mou ZENG Jia Qiang CAI and Yi jian gu(Dalian institute of Chemical Physics, Academia Sinica 161 Zhongshan Rcad Dalian 116012) Acad Sinica Dalian Inst Chem Phys Dalian 116012 Peoples R China

Pyridine and 4-picoline undergo reductive tetraallylation with allyl bromide and zinc dust in THF at room temperature to afford regio-selectively 1,2,3,6-tetraallyl-1,2,3,6-tetrahydropyridine and 1,2,3,6-tetraallyl-1,...

关键词：

Effects of Different Temperature and Time Durations of Virus Inactivation on Results of Real-time Fluorescence PCR Testing of COVID-19 Viruses

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Current Medical Science 2020年第4期40卷 614-617页

作者： Ze-gang WU Hong-yun ZHENG jian gu Feng LI Rui-long LV Ya-yun DENG Wan-zhou XU Yong-qing TONG Department of Clinical Laboratory Rentnin Hospital of Wuhan UniversityWuhan 430060China

Summary:The novel coronavirus SARS-CoV-2 caused an outbreak of pneumonia in Wuhan,Hubei province of China in January *** study aims to investigate the effects of different temperature and time durations of virus inactivation on the results of PCR testing for *** patients at the Renmin Hospital of Wuhan University suspected of being infected with SARS-CoV-2 were selected on February 13,2020 and throat swabs were *** swabs were stored at room tempcrature(20-25℃),then divided into aliquots and subjected to different temperature for different periods in order to inactivate the viruses(56℃for 30,45,60 min;65,70,80℃for 10,15,20 min).Control aliquots were stored at room temperature for 60 *** all aliquots were tested in a real-time fluorescence PCR using primers against *** of inactivation temperature and time,7 of 12 cases(58.3%)tested were positive for SARS-CoV-2 by PCR,and cycle threshold values were *** results suggest that virus inactivation parameters exert minimal infuence on PCR test *** at 65℃for 10 min may be sufficient to ensure safe,reliable testing.

关键词： SARS-CoV-2 COVID-19 throat swabs real-time fluorescence PCR