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MARS and RNAcmap3:The Master database of All Possible RNA Sequences integrated with RNAcmap for RNA Homology Search

Genomics, Proteomics & Bioinformatics 2024年第1期22卷 143-150页

作者： Ke Chen Thomas Litfin Jaswinder Singh jian Zhan Yaoqi Zhou institute of Systems and Physical Biology Shenzhen Bay LaboratoryShenzhen 518055China Peking University Shenzhen Graduate School Shenzhen 518055China University of Science and Technology of China Hefei 230026China Suzhou institute for Advanced Research University of Science and Technology of ChinaSuzhou 215123China institute for Glycomics Griffith UniversitySouthportQLD 4222Australia

sequences found.in the huge,integrated database of protein sequences(Big Fantastic database).in contrast,the existing nucleotide databases were not consolidated to facilitate wider and deeper homology ***,we built a comprehensive database by incorporating the non-coding RNA(ncRNA)sequences from RNAcentral,the transcriptome assembly and metagenome assembly from metagenomics RAST(MG-RAST),the genomic sequences from Genome Warehouse(GWH),and the genomic sequences from MGnify,in ad.ition to the nucleotide(nt)database and.its subsets in National Center of Biotechnology information(NCBi).The resulting Master database of All possible RNA sequences(MARS)is 20-fold larger than NCBi’s nt database or 60-fold larger than *** new dataset along with a new split-search strategy allows a substantial improvement in homology search over existing state-of-the-art *** also yields more accurate and more sensitive multiple sequence alignments(MSAs)than manually curated MSAs from Rfam for the majority of structured RNAs mapped to *** results indicate that MARS coupled with the fully automatic homology search tool RNAcmap will be useful for improved structural and functional inference of ncRNAs and RNA language models based on *** is accessible at https://***/omix/release/OMiX003037,and RNAcmap3 is accessible at http://***/download/.

关键词： RNA sequence database Homology search Secondary structure MARS RNAcmap3

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investigating Periodic dependencies to improve Short-Term Load Forecasting

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Energy Engineering 2024年第3期121卷 789-806页

作者： Jialin Yu Xiaodi Zhang Qi Zhong jian Feng State Grid Zhejiang Jiaxing Electric Power Co. Ltd.Jiaxing314000China State Grid Zhejiang Electric Power Co. Ltd.Hangzhou310000China

With a further increase in energy flexibility for customers,short-term load forecasting is essential to provide benchmarks for economic dispatch and real-time alerts in power *** electrical load series exhibit periodic patterns and share high associations with metrological ***,current studies have merely focused on point-wise models and failed to sufficiently investigate the periodic patterns of load series,which hinders the further improvement of short-term load forecasting ***,this paper improved Autoformer to extract the periodic patterns of load series and learn a representative feature from deep decomposition and *** ad.ition,a novel multi-factor attention mechanism was proposed to handle multi-source metrological and numerical weather prediction data and thus correct the forecasted electrical *** paper also compared the proposed model with various competitive *** the experimental results reveal,the proposed model outperforms the benchmark models and maintains stability on various types of load consumers.

关键词： Load forecasting transformer attention mechanism power grid

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Evaluation of lightning-induced overvoltage on a 10 kV distribution line based on electromagnetic return-stroke model using finite-difference time-domain

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High Voltage 2024年第2期9卷 356-366页

作者： Pan duan Lianfang Zhang Xiaogang Huang jian Sun Yue Qi Qing Yang School of Automation Chongqing University of Posts and TelecommunicationsChongqingChina Chongqing Power Co Tongnan BurChongqingChina China Southern Power Grid Science Research institute GuangzhouChina State Key Laboratory of Power Transmission Equipment&System Security and New Technology Chongqing UniversityChongqingChina

Accurate simulation of lightning-induced overvoltage for overhead distribution lines is helpful to prevent lightning trip *** electromagnetic return-stroke model was used to represent lightning and then a 3d finite-difference time-domain(FdTd)method was adopted to simulate the lightning-induced overvoltage on a distribution line without a field-line coupling *** lightning-induced overvoltage behave for different ground conductivity and varying distance between the distribution line and the lightning channel was *** results showed that the overvoltage waveforms at the centre point of the line corresponding to lightning strikes on the lossy ground and an ideal ground(σ=∞)were similar;however,the peak amplitudes of the waveform were affected by soil conductivity at a close *** relationship between magnitude of the overvoltage and distance can be described by a second-order exponential decay ***,the overvoltage calculated using the proposed model was compared with those obtained based on Agrawal's model and measurements made using the newly developed.intelligent insulator on *** these comparisons,it could be concluded that the FdTd method with the electromagnetic return-stroke model produces reasonably accurate results of the attenuated oscillation waveform,which can better reproduce the overvoltage on operational distribution lines.

关键词： lightning distribution return

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New model of linkage evolution for the transtensional fault systems in the Nanpu Sag of Bohai Bay Basin: insight from seismic interpretation and analogue modelling

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Petroleum Science 2024年第4期21卷 2287-2310页

作者： Yu-Heng Wang Fu-Sheng Yu Bao-Yin Zhao Ling-jian Meng College of Geosciences China University of Petroleum (Beijing) State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum (Beijing) Jidong Oilfield Company PetroChina Limited Company

The evolution of faults within the same stress field.is frequently influenced by numerous factors,involving the reactivation of pre-existing structures, stress transmission through ductile detachment layers, and the growth, interaction, as well as linkage of new fault segments. This study analyses a complex multi-phase oblique extension fault system in the Nanpu Sag(NPS) of the Bohai Bay Basin(BBB),China. High-resolution three-dimensional(3d) seismic data and analogue modelling indicate that the oblique extensional reactivation of pre-existing structures governs the sequential arrangement of fault segments in the caprock, and they dip synthetically to the reactivated fault at depth. during the NW-SE extension in the Eocene, the predominant movement of the pre-existing fault is strike-slip. Subsequently,during the N-S extension since the Oligocene, inclined at *** the pre-existing fault, forming splay fault segments and ultimately creating large en-echelon arcuate faults linked by relay ramps. Using fault throw-distance(T-d) and laser scanning, we reconstructed the fault evolution model of oblique extension reactivation in the presence of a ductile detachment basement. Our study illustrates that the arcuate faults can be categorized.into linear master fault segments controlled by pre-existing structures, bending splay faults in the termination zone, and normal fault segments responding to the regional stress *** interaction between faults occurs among normal faults and strike-slip faults, and the kinematic unification of the two fault systems is accomplished.in the intersection zone. As the faults continue to evolve, the new fault segments tend to relinquish the control of pre-existing structures and concentrate more on the development of planar and continuous major faults. The ductile detachment layer significantly contributes to the uniform distribution of strain, resulting in narrow shear zones and discontinuous normal faults in its absence.

关键词： Analogue modelling Transtensional deformation Fault linkage Fault intersection zone Nanpu Sag of Bohai Bay basin

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interface strengthening for thermal sprayed WC-10Co4Cr coating subjected to pulsed magnetic treatment

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Rare Metals 2024年第2期43卷 780-795页

作者： Cheng-Kai Qian Qu Liu Heng Wang Ke-jian Li Zhi-Peng Cai department of Mechanical Engineering Tsinghua UniversityBeijing100084China Tianjin Research institute for Advanced Equipment Tsinghua UniversityTianjin300304China State Key Laboratory of Tribology in Advanced Equipment Tsinghua UniversityBeijing100084China

The reliability of the coated.industry components demands ideal fatigue properties of the coating,and.it is mainly determined by the performance of the *** this study,pulsed magnetic treatment(PMT)was applied to the thermal sprayed WC-10Co4Cr coating,and the fatigue lifetime of the coated bolt increased by 219.82%under an imitation of the operating mode *** tests further proved that both the adhesion and cohesion strength were improved after PMT,and they benefit from the interface strengthening *** formation of coherent WC/Co interfaces was characterized by in-situ transmission electron microscopy(TEM),and the molecular dynamic simulations indicate that the work of separation of these interfaces is much higher than the original disordered *** stress was relaxed and distributed more homogeneously after PMT,and.it mainly contributes to the coating/substrate *** work provides a new post-treatment method focusing on the interfaces in the WC-based coating and gives insight into its mechanism so that it is hopeful to be applied to other kinds of coatings.

关键词： Cemented carbide coating Pulsed magnetic treatment interface strengthening Fatigue properties Adhesion strength

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Two-photon polymerization-based 4d printing and.its applications

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international Journal of Extreme Manufacturing 2024年第1期6卷 1-25页

作者： Bingcong jian Honggeng Li Xiangnan He Rong Wang Hui Ying Yang Qi Ge Shenzhen Key Laboratory of Soft Mechanics&Smart Manufacturing Southern University of Science and TechnologyShenzhen 518055People’s Republic of China department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Pillar of Engineering Product development Singapore University of Technology and Design8 Somapah RoadSingapore 487372Singapore

Two-photon polymerization(TPP)is a cutting-edge micro/nanoscale three-dimensional(3d)printing technology based on the principle of two-photon *** surpasses the diffraction limit in achieving feature sizes and excels in fabricating intricate 3d micro/nanostructures with exceptional *** concept of 4d entails the fabrication of structures utilizing smart materials capable of undergoing shape,property,or functional changes in response to external stimuli over *** integration of TPP and 4d printing introduces the possibility of producing responsive structures with micro/nanoscale accuracy,thereby enhancing the capabilities and potential applications of both *** paper comprehensively reviews TPP-based 4d printing technology and.its diverse ***,the working principles of TPP and.its recent advancements are ***,the optional4d printing materials suitable for fabrication with TPP are ***,this review paper highlights several noteworthy applications of TPP-based 4d printing,including domains such as biomedical microrobots,bioinspired microactuators,autonomous mobile microrobots,transformable devices and robots,as well as anti-counterfeiting *** conclusion,this paper provides valuable insights into the current status and future prospects of TPP-based4d printing technology,thereby serving as a guide for researchers and practitioners.

关键词： two-photonpolymerization 4d printing nano/micro fabrication microrobot

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Metal–Organic Framework‑Based Photodetectors

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Nano-Micro Letters 2024年第11期16卷 675-703页

作者： Jin‑Biao Zhang Yi‑Bo Tian Zhi‑Gang Gu jian Zhang State Key Laboratory of Structural Chemistry Structure of MatterFujian Institute of ResearchChinese Academy of SciencesFuzhouFujian 350002People’s Republic of China College of Chemistry and Materials Science Fujian Nornal UniversityFuzhou 350007FujianPeople’s Republic of China Fujian Science&Technology innovation Laboratory for Optoelectronic information of China Fuzhou 350108FujianPeople’s Republic of China University of Chinese Academy of Science Beijing 100049People’s Republic of China

The unique and.interesting physical and chemical properties of metal–organic framework(MOF)materials have recently attracted extensive attention in a new generation of photoelectric *** this review,we summarized and discussed the research progress on MOF-based *** methods of preparing MOF-based photodetectors and various types of MOF single crystals and thin film as well as MOF composites are introduced.in ***,the photodetectors applications for X-ray,ultraviolet and.infrared light,biological detectors,and circularly polarized light photodetectors are ***,summaries and challenges are provided for this important research field.

关键词： Metal-organic frameworks Semiconductor Photodetectors

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Structural analysis of conformational changes in the mpox virus A7 protein

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Virologica Sinica 2024年第2期39卷 331-334页

作者： Xincheng Ni Kai Wang Yinze Han jian Lei National Clinical Research Center for Geriatrics and State Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu610041China

dear Editor,The mpox(formerly known as monkeypox)disease caused by the mpox virus(MPXV)has infected more than 89,700 people and.is linked to 157 deaths in 114 countries world.ide as of September 2023(***).Mpox is a zoonotic disease,the first human case of which was reported.in 1970(Breman et al.,1980).Common symptoms in mpox-infected.individuals include fever,myalgia,fatigue,headache,and a characteristic rash(isidro et al.,2022).Current treatments for mpox remain limited,and an in-depth investigation of essential viral protein(s)will help to explore novel drug targets.

关键词： infected headache

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Clinical efficacy of modified Kamikawa anastomosis in patients with laparoscopic proximal gastrectomy

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 113-123页

作者： Chu-Ying Wu jian-An Lin Kai Ye department of Gastrointestinal Surgery The Second Affiliated Hospital of Fujian Medical UniversityQuanzhou 362000Fujian ProvinceChina

BACKGROUNd With the increasing incidence of proximal gastric cancer,laparoscopic proximal gastrectomy has been ***,reflux esophagitis often occurs after traditional esophagogastric *** order to solve this problem,several methods of digestive tract reconstruction have emerged,but the most satisfying method remains to be ***,we modified traditional Kamikawa anastomosis to investigate the appropriate digestive tract reconstruction in laparo-scopic proximal *** the patients were successfully operated on without conversion to *** duration of operation and digestive tract reconstruction were 203.500(150-224)min and 87.500(73-111)min,*** intraoperative amount of bleeding was 20.500 mL±0.696 *** time of postoperative first flatus,the first postoperative fluid.intake,and the postoperative length of stay were 2(1-3)d,4(3-5)d,and 9(8-10)d,*** the patients were followed up for 12-23 *** body mass index at 6 and 12 months after surgery were 22.577 kg/m2±3.098 kg/m2 and 22.594 kg/m2±3.207 kg/m2,*** nutrition risk screening 2002 score,the patient-generated subjective global assessment score,and the gastroesophageal reflux disease scale score were good at 6 and 12 months after *** esophagitis and anastomotic stenosis were not observed.in any of the patients during their 12-month postoperative gastroscopy or upper gastrointestinal tract *** the patients exhibited no tumor recurrence or *** The modified Kamikawa anastomosis is safe and feasible for laparoscopic proximal gastrectomy and has good antireflux effects and nutritional status.

关键词： Modified Kamikawa anastomosis Laparoscopy Proximal gastrectomy Antireflux

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development of a novel staging classification for Siewert Ⅱ adenocarcinoma of the esophagogastric junction after neoadjuvant chemotherapy

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2541-2554页

作者： jian Zhang Hao Liu Hang Yu Wei-Xiang Xu department of Gastrointestinal Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina

BACKGROUNd Stage classification for Siewert Ⅱ adenocarcinoma of the esophagogastric junction(AEG)treated with neoadjuvant chemotherapy(NAC)has not been *** To investigate the optimal stage classification for Siewert Ⅱ AEG with *** A nomogram was established based on Cox regression model that analyzed variables associated with overall survival(OS)and disease-specific survival(dSS).The nomogram performance in terms of discrimination and calibration ability was evaluated using the likelihood-ratio test,Akaike information criterion,Harrell concordance index,time-receiver operating characteristic curve,and decision curve *** data from 725 patients with Siewert type Ⅱ AEG who underwent neoadjuvant therapy and gastrectomy were obtained from the Surveillance,Epidemiology,and End Results *** and multivariate analyses revealed that sex,marital status,race,ypT stage,and ypN stage were independent prognostic factors of OS,whereas sex,race,ypT stage,and ypN stage were independent prognostic factors for *** factors were incorporated.into the OS and dSS *** novel nomogram model performed better in terms of OS and dSS prediction compared to the 8th American Joint Committee of Cancer pathological staging system for esophageal and gastric ***,a user-friendly web application was developed for clinical *** The nomogram established specifically for patients with Siewert type Ⅱ AEG receiving NAC demonstrated good prognostic *** using external data is warranted before its widespread clinical application.

关键词： Stage classification Prognosis Esophagogastric junction cancer Neoadjuvant chemotherapy Siewert type

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