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Mucosa color and size may indicate malignant transformation of chicken skin mucosa-positive colorectal neoplastic polyps

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 750-760页

作者： Ying-Jie Zhang Meng-Xia Yuan wu Wen Fan Li Yi jian Chuan-Ming Zhang Ye Yang Feng-Lin Chen Department of Digestive Diseases Chengdu Second People’s HospitalChengdu 610000Sichuan ProvinceChina Graduate school Chengdu Medical CollegeChengdu 610000Sichuan ProvinceChina

BACKGROUND Lipid metabolism reprogramming is suspected to exist in pre-cancerous lesions,including colorectal *** colonoscopy frequently reveals chicken skin mucosa(CSM;white or yellow-white speckled mucosa)surrounding colo-rectal polyps,caused by macrophages engulfing and accumulating the lipids decomposed by colon cells or adjacent ***-positive colorectal polyps are associated with various diseases;however,their prognosis varies *** snare polypectomy is commonly used to resect lesions up to 10 to 15 mm in diameter without signs of submucosal invasion but is controversial for CSM-positive colorectal *** imaging is required to diagnose and treat CSM-positive colorectal *** This retrospective cohort study included 177 patients with CSM-positive colorectal polyps diagnosed using *** patient-related information was extracted from the Goldisc soft-clinic DICOM system or electronic medical record *** on the pathological results,patients were classified as non-neoplastic polyps(five juvenile polyps),neoplastic polyps,non-invasive high-grade neoplasia(NHGN),or submucosal invasive carcinoma(SM stage cancer).We analyzed and compared the clinical features,suspected risk factors for malignant transformation of neoplastic polyps,and early infiltration of sub-mucosal *** The diameters of NHGN and SM polyps were much smaller than those of neoplastic *** NHGN polyps had a deeper red mucosal *** logistic regression analyses,diameter and deeper red mucosal color were independent risk factors for malignant transformation of neoplastic *** 1 CSM was more common in high-grade intraepithelial neoplasia and SM;type 2 CSM was more common in neoplastic *** regression analyses revealed no significant differences in the malignant transformation of neoplastic polyps or early submucosal invasion of CSM-positive colorectal *** in the CSM mucosa surrounding neoplastic

关键词： Chicken skin mucosa Colorectal cancer Colorectal polyps Endoscopic resection Malignant transformation White light endoscopy

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A symmetric geometric measure and the dynamics of quantum discord

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Chinese Physics B 2013年第4期22卷 94-102页

作者：蒋峰建吕海江闫新虎石名俊 Department of Modern Physics University of Science and Technology of China school of information engineering Huangshan University

A symmetric measure of quantum correlation based on the Hilbert–Schmidt distance is presented in this paper. For two-qubit states, we considerably simplify the optimization procedure so that numerical evaluation can be performed efficiently. Analytical expressions for the quantum correlation are attained for some special states. We further investigate the dynamics of quantum correlation of the system qubits in the presence of independent dissipative environments. Several nontrivial aspects are demonstrated. We find that the quantum correlation can increase even if the system state is suffering from dissipative noise. Sudden changes occur, even twice, in the time evolution of quantum correlation. There exists a certain correspondence between the evolution of quantum correlation in the systems and that in the environments, and the quantum correlation in the systems will be transferred into the environments completely and asymptotically.

关键词： quantum correlation geometric measure

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Experimental study of the effect of gas discharge on ionic liquid electrospray

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Plasma science and technology 2024年第4期26卷 37-43页

作者：石文杨鹏飞宋培义吴健 school of Energy science and engineering Harbin Institute of TechnologyHarbin 150001People’s Republic of China FAW-Volkswagen Automotive Co.Ltd. Changchun 130011People’s Republic of China Center for Gravitational Experiments School of PhysicsHuazhong University of Science and TechnologyWuhan 430074People’s Republic of China

Ionic liquid electrospray(ILE) in an atmospheric environment is often accompanied by the gas discharge phenomenon. It interferes with the normal operation of the electrospray and the measurement of experimental parameters. In this study, electrospray experiments were conducted on the ionic liquid EMI-BF4. The observations revealed that the operating modes of the ionic liquid depend on the voltage polarity at high voltages. Additionally, a correspondence between the operating mode of ILE and the current signal in the circuit was established. The shape of the liquid cone formed at the needle tip bore a striking resemblance to the plume of corona discharge, suggesting that the motion trajectory of electrons influenced the curvature of the liquid cone. Steamer theory provided a clear explanation for the change in curvature as the voltage increased.

关键词： ionic liquid electrospray Taylor cone jet corona discharge

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求解连续函数优化问题的改进蚁群算法及仿真

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系统仿真学报 2009年第6期21卷 1685-1688页

作者：周建新杨卫东李擎北京科技大学信息工程学院北京100083

蚁群算法是近几年优化领域中新出现的一种启发式仿生类并行智能进化算法,该算法采用分布式并行计算和正反馈机制,易于与其它方法结合,目前虽然已经在离散空间优化领域中得到了广泛应用,但是在求解连续空间优化问题方面的研究相对较少。... 详细信息

蚁群算法是近几年优化领域中新出现的一种启发式仿生类并行智能进化算法,该算法采用分布式并行计算和正反馈机制,易于与其它方法结合,目前虽然已经在离散空间优化领域中得到了广泛应用,但是在求解连续空间优化问题方面的研究相对较少。在介绍基本蚁群算法机制原理和数学模型的基础上,对信息素更新方式进行了改进,采用动态局部信息素更新方式和自适应调节信息素挥发的全局信息素更新方式相结合,并将各条寻优路径上可能的残留信息素数量限制在一个最大最小区间,以提高改进后蚁群算法的全局收敛性能。仿真实验表明,提出的改进蚁群算法能更快地找到连续空间优化问题更优良的全局解,从而为蚁群算法求解这类问题提供了一条可行有效的新途径。

关键词：蚁群算法连续空间优化信息素旅行商问题

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Orbital angular momentum conversion of acoustic vortex beams via planar lattice coupling

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Chinese Physics B 2024年第9期33卷 413-420页

作者： Qingbang Han Zhipeng Liu Cheng Yin Simeng wu Yinlong Luo Zixin Yang Xiuyang Pang Yiqiu Wang Xuefen Kan Yuqiu Zhang Qiang Yu jian wu College of information science and engineering Hohai UniversityChangzhou 213200China College of Advanced Interdisciplinary Studies Nanhu Laser LaboratoryNational University ofDefense TechnologyChangsha 410073China school of Transportation engineering Jiangsu Shipping CollegeNantong 226010China i-Lab Suzhou Institute of Nano-Tech and Nano-BionicsChinese Academy of SciencesSuzhou215123China

Orbital angular momentum(OAM)conversion is critical in understanding interactions between a structural sound field and a planar ***,we explore the evolution of a monochromatic acoustic vortex beam(AVB)that is scattered by a phononic crystal(PnC)or a correlated random *** phenomenon is ascribed to the enhanced orbit–orbit angular momentum coupling induced by the band *** modifying the coupling condition,accurate and continuous micromanipulation of AVBs can be achieved,including the transverse/lateral gravity shift,the dynamics of the phase singularities,and the spatial distribution of acoustic pressure,*** research provides insight to the inhomogeneous coupling of AVBs with both propagating Bloch waves and localized Anderson modes,and may facilitate development of novel OAM-based acoustic devices for active sound field manipulation.

关键词： acoustic vortex beam phononic crystal Anderson localization Imbert–Fedorov effect

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Glycodiversification of gentamicins through in vivo glycosyltransferase swapping enabled the creation of novel hybrid aminoglycoside antibiotics with potent activity and low ototoxicity

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Acta Pharmaceutica Sinica B 2024年第9期14卷 4149-4163页

作者： Xinyun jian Cheng Wang Shijuan wu Guo Sun Chuan Huang Chengbing Qiu Yuanzheng Liu Peter FLeadlay Dong Liu Zixin Deng Fuling Zhou Yuhui Sun Department of Hematology Zhongnan Hospital of Wuhan UniversitySchool of Pharmaceutical SciencesWuhan UniversityWuhan 430071China Key Laboratory of Combinatorial Biosynthesis and Drug Discovery(Ministry of Education) Wuhan UniversityWuhan 430071China school of Pharmacy Huazhong University of Science and TechnologyWuhan 430030China school of Life sciences Co-Innovation Center of NeuroregenerationNantong Laboratory of Development and DiseasesNantong UniversityNantong 226019China Department of Biochemistry University of CambridgeCambridge CB21GAUK Department of Biochemistry and Molecular Biology Biomedicine Discovery InstituteMonash UniversityClayton VIC 3800Australia ARC Centre of Excellence for Innovations in Protein and Peptide science Monash UniversityClayton VIC 3800Australia

Aminoglycosides(AGs)are a class of antibiotics with a broad spectrum of ***,their use is limited by safety concerns associated with nephrotoxicity and ototoxicity,as well as drug *** address these issues,semi-synthetic approaches for modifying natural AGs have generated new generations of AGs,however,with limited types of modification due to significant challenges in *** study explores a novel approach that harness the bacterial biosynthetic machinery of gentamicins and kanamycins to create hybrid *** was achieved by glycodiversification of gentamicins via swapping the glycosyltransferase(GT)in their producer with the GT from kanamycins biosynthetic pathway and resulted in the creation of a series of novel AGs,therefore referred to as genkamicins(GKs).The manipulation of the hybrid biosynthetic pathway enabled the targeted accumulation of different GK species and the isolation and characterization of six GK *** compounds display retained antimicrobial activity against a panel of World Health Organization(WHO)critical priority pathogens,and GK-C2a,in particular,demonstrates low ototoxicity compared to clinical drugs in zebrafish *** study provides a new strategy for diversifying the structure of AGs and a potential avenue for developing less toxic AG drugs to combat infectious diseases.

关键词： Antibiotic Aminoglycoside biosynthesis Biosynthetic engineering Ototoxicity

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Ant colony algorithm based restoration routing for WDM networks

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微计算机信息 2008年第33期 99-101页

作者： jian Yao-bo RUAN Shuang-chen YANG Chun-yong(Institute of Optoelectronics science and engineering,Huazhong university of science and technology,430074 wuhan china)(College of Electronic science and technology,ShenZhen university,518060 Shenzhen china)(College of Electronics & information engineering,South-central university for Nationalities,430074 wuhan china)

Ant colony algorithm-restoration algorithm(ACA-RA)is a novel simulated evolutionary *** is a population-based approach,which allows positive feedback to be used as the primary search mechanism and provides a new method for compli-cated combinatorial optimization *** this paper,selecting strategy,local searching and information modification are *** improved algorithm is used to search optimal restoration routes in case various failures take place in WDM *** valid result is proven by an algorithm simulation in a practical network chinaNET.

关键词： wavelength division multiplexing ant colony algorithm wavelength routing open shortest path first algorithm breath-first-search algorithm

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Hydrogen production from hydrolysis of NaBH_(4) solution over Co-Fe-B@g-C_(3)N_(4)/NF thin film catalyst

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Rare Metals 2024年第6期43卷 2648-2659页

作者： Yan Wang Jia-Xin Ma jian Ren Di Zhang Feng-Yan Xu Ke Zhang Zhong-Qiu Cao Qiu-Ju Sun Guo-De Li Shi-Wei wu Hong-Hui Chen College of Chemistry and Chemical engineering Shenyang Normal UniversityShenyang 110034China Experimental Center Shenyang Normal UniversityShenyang 110034China Hunan Shande Energy Storage New Materials Research Institute Limited Company Changde 415000China

In this study,the double loaded Co-Fe-B@g-C_(3)N_(4)/NF(NF:Ni foam)thin film catalysts were prepared for the first time via chemical deposition method at room *** optimizing the reducing agent concentration to 0.9 mol·L^(-1),the as-obtained Co-Fe-B@g-C_(3)N_(4)/NF exhibited the twisted ribbon structure with more distinct three-dimensional hierarchy and the smaller particle size,showing the good catalytic property for the hydrolysis of NaBH_(4)*** H_(2)generation rate of Co-Fe-B@g-C_(3)N_(4)/NF and binary Co-B@g-C_(3)N_(4)/NF under visible light irradiation surpassed the value under natural *** apparent activation energy of Co-Fe-B@g-C_(3)N_(4)/NF(45.0 kJ·mol^(-1))under visible light irradiation was obviously reduced when compared with the natural condition(48.4 kJ·mol^(-1))and binary Co-B@g-C_(3)N_(4)/NF(60.6 kJ·mol^(-1))under visible light ***,the catalytic performance of the optimized Co-Fe-B@g-C_(3)N_(4)/NF thin film catalyst was superior to most of the reported non-noble metal and even noble metal ***,it illustrated that the catalytic H_(2)production performance of Co-Fe-B@g-C_(3)N_(4)/NF thin film was distinctly improved after the introduction of light and multicomponent recombination.

关键词： Sodium borohydride Co-Fe-B@g-C_(3)N_(4)/NF catalyst Chemical deposition Hydrogen production

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Tube-Wall Temperature Prediction of a 660-MW Ultra-Supercritical Double-Reheat Boiler under Flexible Peak Shaving

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Journal of Thermal science 2024年第06期33卷 2372-2385页

作者： XU Jiaye FAN Haojie wu Xiaojiang ZHANG jian YE Nina ZHANG Qichao ZHANG Zhongxiao school of Mechanical engineering Shanghai Jiao Tong University

Ultra-supercritical double-reheat boilers employ multiple temperature-regulating methods during flexible peak *** exposes the boiler to significant tube-wall temperature deviations and *** this study,a compartment model was developed to subdivide the overlapping high-temperature heating surfaces of a 660-MW double-reheat boiler into smaller *** model was verified using field experimental data and was applied to calculate the enthalpy and tube-wall temperature distributions under different *** addition,the effects of three temperature-regulating methods(swinging burners,regulating dampers,and flue gas recirculation) on the variation tendency and deviations of the tube-wall temperature were *** results indicated that overtemperatures occurred in the high-temperature superheater under a low *** regulating damper method caused the high-temperature secondary reheater to exceed the permissible temperature by 21.4℃.The tube-wall temperature exhibited a bimodal distribution along the *** 0% flue gas recirculation,the maximum tube-wall temperature deviation attained 13.39℃,exceeding a reasonable value by 3.39℃.The swinging burner method was the least likely to cause tube-wall temperature deviations and *** reasonable regulation ranges for swinging burners,regulating dampers,and flue gas recirculation were-20° to 7°,45% to 60%,and 8% to 24%,*** on different flexible peak shaving constraints,an appropriate temperature-regulating method was selected,and the regulation range was specified.

关键词： compartment model double-reheat boiler enthalpy distribution flexible peak shaving tube-wall temperature

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Product quality prediction based on RBF optimized by firefly algorithm

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Journal of Systems engineering and Electronics 2024年第1期35卷 105-117页

作者： HAN Huihui WANG jian CHEN Sen YAN Manting College of Electronics and information engineering Tongji UniversityShanghai 201804China

With the development of information technology,a large number of product quality data in the entire manufacturing process is accumulated,but it is not explored and used *** traditional product quality prediction models have many disadvantages,such as high complexity and low *** overcome the above problems,we propose an optimized data equalization method to pre-process dataset and design a simple but effective product quality prediction model:radial basis function model optimized by the firefly algorithm with Levy flight mechanism(RBFFALM).First,the new data equalization method is introduced to pre-process the dataset,which reduces the dimension of the data,removes redundant features,and improves the data *** the RBFFALFM is used to predict product *** expe riments conducted on real-world product quality datasets validate that the new model RBFFALFM combining with the new data pre-processing method outperforms other previous me thods on predicting product quality.

关键词： product quality prediction data pre-processing radial basis function swarm intelligence optimization algorithm

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