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Evolution and current status of the subclassification of intermediate hepatocellular carcinoma

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World Journal of Gastrointestinal Surgery 2020年第3期12卷 85-92页

作者： Peng-Sheng Yi Hong Wang jian-shui Li Department of Hepato-biliary-pancrease Affiliated Hospital of North Sichuan Medical CollegeNanchong 637000Sichuan ProvinceChina Department of Orthopedics Affiliated Hospital of Guizhou Medical UniversityGuiyang 550001Guizhou ProvinceChina

The staging and treatment of intermediate hepatocellular carcinoma(HCC)remains *** to the recommendations of Barcelona Clinic Liver Cancer staging system,patients with intermediate HCC are candidates for transcatheter arterial ***,not all patients with intermediate HCC benefit from transcatheter arterial ***,it is meaningful to propose a novel staging system of intermediate HCC in order to allocate different treatments for different *** et al proposed the first subclassification system of intermediate ***,investigators performed studies to validate the feasibility of Bolondi’s criteria and proposed several novel staging *** present study reviewed the literatures and provided a general overview of the evolution and current status of the subclassification of intermediate *** propose to expand the indication of liver resection and add radical treatments as the first option of the treatment for patients with intermediate HCC.

关键词： Subclassification Intermediate hepatocellular carcinoma Treatment Staging Transcatheter arterial chemoembolization Liver resection

High level of ezrin expression in colorectal cancer tissues is closely related to tumor malignancy

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World Journal of Gastroenterology 2009年第16期15卷 2016-2019页

作者： Hong-jian Wang Jin-shui Zhu Qiang Zhang Qun Sun Hua Guo Department of Gastroenterology The Sixth People's Hospital Affiliated to Shanghai Jiao Tong University Shanghai 200233 China

AIM:To investigate the ezrin expression in normal colorectal mucosa and colorectal cancer tissues, and study the correlation between ezrin expression in colorectal cancer tissues and tumor invasion and ***: Eighty paraffin-embedded cancer tissue samples were selected from primary colorectal adenocarcinoma. Twenty-eight patients had well-differentiated, 22 had moderately differentiated and 30 had poorly differentiated adenocarcinoma. Forty-five patients and 35 patients had lymph node metastasis. Forty-five patients were of Dukes A to B stage, and 35 were of C to D stage. Another 22 paraffi n-embedded tissue blocks of normal colorectal epithelium (>5 cm away from the edge of the tumor) were selected as the control group. All patients with colorectal cancer were treated surgically and diagnosed histologically, without preoperative chemotherapy or radiotherapy. The immunohistochemistry was used to detect the ezrin expression in paraffin-embedded normal colorectal mucosa tissues and colorectal cancer tissue ***: Ezrin expression in colorectal cancer was significantly higher than in normal colorectal mucosa (75.00% vs 9.09%, P<0.01), and there was a close relationship between ezrin expression and the degree of tumor differentiation, lymph node metastasis and Dukes stage (88.46% vs 50.00%, P<0.01; 94.28% vs 51.11%, P<0.01; 94.28% vs 51.11%, P<0.01).CONCLUSION: Ezrin expression is obviously higher in colorectal cancer tissues than in normal colorectal mucosa tissues, and the high level of ezrin expression is closely related to the colorectal cancer invasion and metastasis process.

关键词： Colorectal cancer Ezrin Malignant tumor Invasion Metastasis Immunohistochemistry

Chirped Fiber Bragg Gratings for Optieal Fiber Dispersion Compensation

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Chinese Physics Letters 1996年第11期13卷 848-850页

作者： CHEN Gen-xiang LI Xun YANG Ling jian shui-sheng GE Huang WANG Wei Institute of Lightwave Technology Northern Jiaotong UniversityBeijing 100044 Department of Electronical and Computer Engineering University of WaterlooWaterlooOntarioCanada N2L 3G1 National Research Center for Optoelectronics Technology Institute of SemiconductorChinese Academy of SciencesBeijing 100083

The use of α-power chirped fiber Bragg gratings for dispersion Cancellation in an optical fiber link is *** and theoretical investigation of recompressing the dispersion-broadened pulse by usingα-power chirped gratings is made,which shows that,the dispersion-broadened Gaussian pulse after l00km standard fiber(with zero dispersion atλ=1.3μm)trnasmission atλ=1.55μm with initial width of T_(FWHM)=33ps(full width at half maximum)can be perfectly recompressed with the peak reflectivity of 82%by using a 30mm longα-power chirped fiber grating with properαvalue and optimal grating parameters.

关键词： fiber pulse dispersion

Retrospective analysis of 88 patients with pancreatic duct stone

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Hepatobiliary & Pancreatic Diseases International 2007年第2期6卷 208-212页

作者： Li, jian-shui Zhang, Zhao-Da Tang, Yong jiang, Rong N Sichuan Med Coll Dept Gen Surg Affiliated Hosp Nanchong 637000 Peoples R China Sichuan Univ W China Hosp Dept Gen Surg Chengdu 610041 Peoples R China

BACKGROUND: Pancreatic duct stone is a rare disease, but there appears to be a rising trend in its incidence in recent years. Its pathogenesis remains unknown. The causes, diagnosis and treatment of pancreatic duct stone are reviewed through a retrospective analysis of the cases treated in our hospital. METHODS: The medical records of 88 patients with pancreatic duct stone treated in West China Hospital, Sichuan University from January 1, 1998 to November 30, 2004 were analyzed retrospectively in terms of clinical characteristics, diagnosis and treatment. RESULTS: Epigastric pain was the most common symptom in the 88 patients with an average age of 45.44 +/- 6.72 years. Various other symptoms were also observed. Eighty-one patients were subjected to B-ultrasonography, 51 to CT, and 47 to magnetic resonance cholangiopancreatography (MRCP). Fifty-six patients (63.64%) were operated on, 25 (28.41%) were treated with Chinese and Western medicine, and 7 (7.95%) abandoned treatment. Chronic pancreatitis was pathologically confirmed in all patients undergoing operation. CONCLUSIONS: B-ultrasonography is the first choice to check for pancreatic duct stone, while MRCP proves instructively useful for the diagnosis and treatment. Chronic pancreatitis is the most important cause of pancreatic duct stone, but whether there is not a direct correlation between stone formation and alcohol abuse needs further study in China. Surgery is the most curative method for pancreatic duct stone patients with severe symptoms or suspected pancreatic carcinoma, while individual treatment is emphasized, and microtraumatic surgery may be a developing option for treating pancreatic stone.

关键词： pancreatic duct stone diagnosis treatment MRCP

Spectral Properties of Fabry-Pérot Laser Diodes and Conventional Semiconductor Optical Amplifiers

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The Journal of China Universities of Posts and Telecommunications 2006年第1期13卷 63-66页

作者： CHEN Gen-xiang LI Wei XU Cheng-lin HUANG Wei-ping jian shui-sheng Key Laboratory of All Optical and Advanced Telecommunication Networks Beijing Jiaotong University Beijing 100044 P.R. China Department of Chemical and Engineering Physics University of Wisconsin-PlatteviUe Platteville 53818 WI USA Department of Electrical and Computer Engineering McMaster University Hamilton I..8S 4K1 Ontario Canada

This paper presents an unified comprehensive model for the analysis of the spectral properties of Fabry-Perot laser diodes and conventional semiconductor optical amplifiers. We develop the model by considering the wide-band amplified spontaneous emission fields and the input optical signal fields in a general frame. Specifically, this paper discusses theoretical aspects of the model in details, which are based upon the spectra of material gain and spontaneous emission power, nonlinear gain suppression, and longitudinal spatial hole burning. This paper also presents simulation results of the model for the case of conventional semiconductor optical amplifier and the case of Fabry-Perot laser diode to demonstrate its capabilities.

关键词： semiconductor optical amplifier laser diode amplified spontaneous emission traveling-wave model

Emission and Fixation of CO_2 from Soil System as Influenced by Long-Term Application of Organic Manure in Paddy Soils

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Agricultural Sciences in China 2006年第6期5卷 456-461页

作者： CHEN Yi WU Chun-yan shui jian-guo WANG Jia-yu Institute of Environmental Resources ＆ Soil Fertilizer Zhejiang Academy of Agricultural Sciences Hangzhou 310021 P.R.China

The observations of 25-yr long-term experiment in Zhejiang paddy soils showed that the soil organic matter could increase continuously with applying organic manure, and the increase in rate enhanced along with the application rates of organic manure. By mathematical modeling, the soil organic matter increased by 22 kg when 1 t of fresh FYM was applied. The CO2 emission resulting from the mineralization of soil organic matter increased with the increase in the application rate of the organic manure as well as the increase in the root residues. It is expected that the CO2 emission will be at 10.04-21.61 t ha-1 yr-1 when 16.5-49.5 t ha-1 yr-1 of fresh FYM is applied. The soil organic carbon from mineralization and release of applied organic carbon (fresh FYM and root residues) will affect the CO2 concentration in the atmosphere. So, the higher the application rate of organic manure, the more is the fixed organic carbon. The CO2 fixation will be at 1.885-3.463 t ha-1 yr-1 when 16.5-49.5 t ha-1 yr-1 of fresh FYM is applied. Thus, the CO2 fixation will increase by 46.7 kg by applying 1 t fresh FYM. To apply organic manure continuously in rice fields may reduce the contribution to the increase of CO2 concentration in the atmosphere.

关键词： paddy soil organic manure carbon cycle carbon dioxide global climatic changes

Ecological and Economic Benefits of Vegetation Management Measures in Citrus Orchards on Red Soils

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Pedosphere 2008年第2期18卷 214-221页

作者： shui jian-Guo WANG Qiu-Zhen LIAO Gen-Qing J. AU J. L. ALLARD Institute of Environmental Resources and Soil Fertilizer Zhejiang Academy of Agricultural Sciences Hangzhou 310021 （China） College of Management Zhejiang University Hangzhou 310027 （China） Soil ＆ Fertilizer Station of Wucheng District Jinhua 321000 （China） Syngenta （China） Investment Co. Ltd. Shanghai 200041 （China） Syngenta Asia Pacific Pte. Ltd. 250 North Bridge Road Singapore 179101 （Singapore）

A three-year experiment was conducted to investigate and compare the economic and ecological benefits of six types of vegetation management measures in citrus orchards of the hilly red soil region of the eastern part of *** vegetation treatments,including tillage without herbicide(clean tillage)and no tillage without herbicide(sod culture) and with herbicide paraquat(paraquat),glyphosate(glyphosate),glyphosate-glyphosate-paraquat(G-G-P),and paraquat- paraquat-glyphosate(P-P-G),were applied in the citrus orchards on a clayey red soil with slopes of 8°and 13°and a sandy soil with slope of 25°.The results showed that the sod culture,paraquat,glyphosate,G-G-P,and P-P-G treatments reduced surface runoff by 38.8%,42.5%,18.7%,28.7%,and 37.5%,then the soil-water losses by 55.5%,51.7%,39.9%,46.8%, and 50.0%,and the N,P,and K nutrient losses by 60.3%,50.2%,37.0%,41.8%,and 45.4%,respectively,as compared with the clean tillage *** weed regeneration ratios with the treatments of clean tillage without herbicide,paraquat, glyphosate,G-G-P,and P-P-G were reduced by 55.1%,67.2%,30.3%,36.8%,and 51.2%,respectively,as compared with the sod *** sod culture,paraquat,glyphosate,G-G-P,and P-P-G treatments could increase the soil fertility (annual accumulation of N,P,K,and OM)by 7.1%,6.9%,5.3%,6.2%,and 6.6%,respectively,whereas the clean tillage treatment without herbicide reduced soil fertility by 4.4% after the three-year *** citrus fruit yields in the treatments of paraquat,glyphosate,G-G-P,and P-P-G increased by 7%-10%;the soluble solid,total sugar,total acidity,sugar-acid ratio,and single fruit weight of citrus fruits of all treatments except sod culture significantly(P>0.05) exceeded that of the clean tillage *** general,the paraquat treatment showed the best economic and ecological benefits among the six treatments;therefore,it could be regarded as the best available vegetation management measure in citrus orchards of hilly red soil region

关键词： benefits citrus herbicide red soil vegetation management

Design and Optimization of a novel structure for efficient side-coupling of high power double-cladding fiber lasers

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Optoelectronics Letters 2007年第5期3卷 349-352页

作者： ZHANG Fan WANG Chun-can RUI Geng jian shui-sheng Institute of Lightwave Technology Beijing Jiaotong University Beijing 100044 China

A novel structure for efficient side-coupling of high power double-cladding fiber lasers is presented. The maximum cou- pling efficiency of this structure is more than 90% for TM-polarization in the +1 and -1 order but is only 40% for TE- polarization. Thus, a multi-layer stair-structure is introduced and optimized by combining transmission algorithm and genetic algorithm to obtain higher coupling efficiencyηfor TE-polarization and the maximum coupling efficiency almost reaches to 70%.

关键词：光学纤维激光器偏振结构传播途径

Multi-Beam Interference Transmission Spectrum Observed from an Eccentric Core Single-Mode Fiber

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Chinese Physics Letters 2011年第2期28卷 122-125页

作者： FAN Lin-Yong jianG Wei-Wei ZHAO Rui-Feng PEI Li jian shui-Sheng Institute of Lightwave Technology Beijing Jiaotong UniversityBeijing 100044 Key Lab of All Optical Network and Advanced Telecommunication Network of EMC Beijing Jiaotong UniversityBeijing 100044

An eccentric core single-mode fiber,whose core is away from the axis of the fiber,is fabricated by using the fiber preform goniometric-groove method and the stack-and-draw *** eccentric core single-mode fiber without coating is spliced between two single-mode *** mode and cladding modes are excited at one splicing point between the eccentric core single-mode fiber and the single-mode fiber,and propagate in the eccentric core single-mode fiber,then interfere with each other at the other splicing ***-beam interference transmission spectrum is *** in-line fiber interferometric strain sensor based on the eccentric core single-mode fiber is realized.

关键词： fiber mode cladding